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The map label for this gene is tolC [C]

Identifier: 78222588

GI number: 78222588

Start: 1537900

End: 1539207

Strand: Reverse

Name: tolC [C]

Synonym: Gmet_1376

Alternate gene names: 78222588

Gene position: 1539207-1537900 (Counterclockwise)

Preceding gene: 78222589

Following gene: 78222587

Centisome position: 38.51

GC content: 62.92

Gene sequence:

>1308_bases
ATGCAGAACAACCAGAATGCACCCATTCCTCAATCGACAGTACCGAGACTCCTTGCGGCCCTGGCGGCGGTTCTCTCCCT
GGCGGGAACGGCACGCGCCGAAACCCTTTCCCTTGCTGAGTGCCTGCGCCGGGCAGCCGCCGGCAACTATGACCTGACCG
TAACGGCCCATGACACGCGCATCGCCGCCGAGAACATTTCCCAGGCCAAGAGCGGCTTTCTCCCCCGCCTCGATTTCCAG
GGGGGATACACCGCCCAGGCCAGGCCCCAGGCTTTTTCCTTCGCGGGACGCGAAACCGAAACCCAGGACGCCACTTACGG
ATTCTTCAACGTCACTGCCACCCAGACCATCTACGACTTCGGCCACACCTCTTCCCGCACCAGGAGGGCATCGCTCCTCC
AGGAGGCGATCACACACAGCTACGACGCACGGGAGAAGGATGTCTTCCTCCAGGTGGTGGAGGCCTACTACGGGATCCTT
GAAGCGAAAAAGGTTCTCGGCGCCGCCGACGAAGAGATCGTACAGCGCACCGACCATCTGGGAGTGGCCCAAAACCTGTA
CGAACAGGGAGTGGTGACCCGTAACGACCTTCTCCAGGCCGAGGTGAAGCTGGCCGACAGCCGGCAGAGGCGTCTCGCGG
CGGCAAACTTCGTTGAGAACCGCTGGCTTTTCCTCAACTATCTGACGGGACGCCCTCTCCCGTTCCGGGCCAACCTGGAG
GAGAAGGATACCCCGGCGTCCCTTCCGCCACTTGAAACAGCCGAAGAGAAGGCCCTGGCGAACCGCCCCGAGCTCGCCTC
TCTCACCAGGACGGTGGAGGCAGGAGAAGCAGGGGTATCCGAAGCCCGGACCGGCTTCTACCCGGAGATCTTCGCCCAGG
GGACCATCGACTACATGGAGAACAGCAAGGCGCGGGAGCAGGCCATCTATGCTGCCACCGTGGGGTTGCGCGTCAACCTC
TTTGATGGCTTCGCCACCACGTCGCGATACCGCCAGGCAGTGGCAAACCTGAGGAAGCAGCGGGACAGCCTCCGTCAGGC
CCGGGAACAGATCCGCCTTGAACTGGCAACGTCCCTGAACGATGCCAGGGTTGCCGCCGAGCGGATCAGGACCGTGGAAA
CGGCAATCAAGCAGGGGGAAGAGAATCTGCGCATCAACCGCGACCGCTATCAGGCCCAGGTGGGGACCGCGACCGACGTC
ATCGACGCCCAGACGCTCCTTACCCAGATCAGGACCGACTATTTCCGCGCCGTCTTCGACTACCAGGTGGCGGCGGCGCG
GGTCAGAAAAGCGATGGGAGAACTGTAG

Upstream 100 bases:

>100_bases
CCCGGGTGACGGAAACATTCCTTTCTCCCCTCACCGCAGAGGAATGTGCCGCCCTGCGCTTCACCCTCAAGAAACTGCGC
CAGTAACGGGAGGATTCTCC

Downstream 100 bases:

>100_bases
TCATGGCAGTGGAAGAATCGAAGGAAAATCAAGGGGCGGGAGAAACCGCCAGAACCGCAACGGATACGGCCGGCCCAGCG
GGCAAGCAGCGGGGAGGGAA

Product: Outer membrane efflux protein

Products: NA

Alternate protein names: LC Family Type I Secretion Outer Membrane Protein; Type I Secretion Outer Membrane Protein lC Family; Outer Membrane Protein; Type I Secretion Outer Membrane Protein lC; Type I Secretion Outer Membrane Protein; Outer Membrane Efflux Family Protein; Outer Membrane Protein lC; Agglutination Protein; RND Family Efflux Pump Outer Membrane Protein; Outer Membrane Channel Protein; Outer Membrane Macrolide Efflux Protein; Acriflavin Resistance Protein; Outer Membrane Secretion Protein; Efflux System Outer Membrane Protein; Outer Membrane Efflux Protein Domain Protein; RND Family Outer Membrane Efflux Protein; Outer Membrane Protein-Like; Outer Membrane Transport/Efflux Protein; RND Family Efflux Pump Inner Membrane Protein; Type I Secretion Outer Membrane Protein lc Family; ABC Export System Outer Membrane Protein; Tranporter Outer Membrane Factor Family; Secretion Protein; Outer Membrane Export Factor

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MQNNQNAPIPQSTVPRLLAALAAVLSLAGTARAETLSLAECLRRAAAGNYDLTVTAHDTRIAAENISQAKSGFLPRLDFQ
GGYTAQARPQAFSFAGRETETQDATYGFFNVTATQTIYDFGHTSSRTRRASLLQEAITHSYDAREKDVFLQVVEAYYGIL
EAKKVLGAADEEIVQRTDHLGVAQNLYEQGVVTRNDLLQAEVKLADSRQRRLAAANFVENRWLFLNYLTGRPLPFRANLE
EKDTPASLPPLETAEEKALANRPELASLTRTVEAGEAGVSEARTGFYPEIFAQGTIDYMENSKAREQAIYAATVGLRVNL
FDGFATTSRYRQAVANLRKQRDSLRQAREQIRLELATSLNDARVAAERIRTVETAIKQGEENLRINRDRYQAQVGTATDV
IDAQTLLTQIRTDYFRAVFDYQVAAARVRKAMGEL

Sequences:

>Translated_435_residues
MQNNQNAPIPQSTVPRLLAALAAVLSLAGTARAETLSLAECLRRAAAGNYDLTVTAHDTRIAAENISQAKSGFLPRLDFQ
GGYTAQARPQAFSFAGRETETQDATYGFFNVTATQTIYDFGHTSSRTRRASLLQEAITHSYDAREKDVFLQVVEAYYGIL
EAKKVLGAADEEIVQRTDHLGVAQNLYEQGVVTRNDLLQAEVKLADSRQRRLAAANFVENRWLFLNYLTGRPLPFRANLE
EKDTPASLPPLETAEEKALANRPELASLTRTVEAGEAGVSEARTGFYPEIFAQGTIDYMENSKAREQAIYAATVGLRVNL
FDGFATTSRYRQAVANLRKQRDSLRQAREQIRLELATSLNDARVAAERIRTVETAIKQGEENLRINRDRYQAQVGTATDV
IDAQTLLTQIRTDYFRAVFDYQVAAARVRKAMGEL
>Mature_435_residues
MQNNQNAPIPQSTVPRLLAALAAVLSLAGTARAETLSLAECLRRAAAGNYDLTVTAHDTRIAAENISQAKSGFLPRLDFQ
GGYTAQARPQAFSFAGRETETQDATYGFFNVTATQTIYDFGHTSSRTRRASLLQEAITHSYDAREKDVFLQVVEAYYGIL
EAKKVLGAADEEIVQRTDHLGVAQNLYEQGVVTRNDLLQAEVKLADSRQRRLAAANFVENRWLFLNYLTGRPLPFRANLE
EKDTPASLPPLETAEEKALANRPELASLTRTVEAGEAGVSEARTGFYPEIFAQGTIDYMENSKAREQAIYAATVGLRVNL
FDGFATTSRYRQAVANLRKQRDSLRQAREQIRLELATSLNDARVAAERIRTVETAIKQGEENLRINRDRYQAQVGTATDV
IDAQTLLTQIRTDYFRAVFDYQVAAARVRKAMGEL

Specific function: Required For Proper Expression Of Outer Membrane Protein Genes Such As Ompf, Nmpc, Protein 2, Hemolysin, Colicin V, Or Colicin E1. May Be Specialized For Signal Sequence Independent, Extracellular Secretion In Gram-Negative Bacteria. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Outer Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 48339; Mature: 48339

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNNQNAPIPQSTVPRLLAALAAVLSLAGTARAETLSLAECLRRAAAGNYDLTVTAHDTR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCH
IAAENISQAKSGFLPRLDFQGGYTAQARPQAFSFAGRETETQDATYGFFNVTATQTIYDF
HHHHHHHHHHHCCCCCEECCCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEHHHHHHHC
GHTSSRTRRASLLQEAITHSYDAREKDVFLQVVEAYYGILEAKKVLGAADEEIVQRTDHL
CCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GVAQNLYEQGVVTRNDLLQAEVKLADSRQRRLAAANFVENRWLFLNYLTGRPLPFRANLE
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCC
EKDTPASLPPLETAEEKALANRPELASLTRTVEAGEAGVSEARTGFYPEIFAQGTIDYME
CCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCHHHHCCCCCHHHHHCCCHHHHH
NSKAREQAIYAATVGLRVNLFDGFATTSRYRQAVANLRKQRDSLRQAREQIRLELATSLN
CCHHHHHHHHHEEECEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DARVAAERIRTVETAIKQGEENLRINRDRYQAQVGTATDVIDAQTLLTQIRTDYFRAVFD
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
YQVAAARVRKAMGEL
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MQNNQNAPIPQSTVPRLLAALAAVLSLAGTARAETLSLAECLRRAAAGNYDLTVTAHDTR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCH
IAAENISQAKSGFLPRLDFQGGYTAQARPQAFSFAGRETETQDATYGFFNVTATQTIYDF
HHHHHHHHHHHCCCCCEECCCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEHHHHHHHC
GHTSSRTRRASLLQEAITHSYDAREKDVFLQVVEAYYGILEAKKVLGAADEEIVQRTDHL
CCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GVAQNLYEQGVVTRNDLLQAEVKLADSRQRRLAAANFVENRWLFLNYLTGRPLPFRANLE
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCC
EKDTPASLPPLETAEEKALANRPELASLTRTVEAGEAGVSEARTGFYPEIFAQGTIDYME
CCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCHHHHCCCCCHHHHHCCCHHHHH
NSKAREQAIYAATVGLRVNLFDGFATTSRYRQAVANLRKQRDSLRQAREQIRLELATSLN
CCHHHHHHHHHEEECEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DARVAAERIRTVETAIKQGEENLRINRDRYQAQVGTATDVIDAQTLLTQIRTDYFRAVFD
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
YQVAAARVRKAMGEL
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA