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The map label for this gene is phoP [H]

Identifier: 78222505

GI number: 78222505

Start: 1451204

End: 1451926

Strand: Reverse

Name: phoP [H]

Synonym: Gmet_1291

Alternate gene names: 78222505

Gene position: 1451926-1451204 (Counterclockwise)

Preceding gene: 78222506

Following gene: 78222488

Centisome position: 36.32

GC content: 60.58

Gene sequence:

>723_bases
ATGACCGAAGAAAAACCCCACATCCTCCTGGTTGAAGACGAGATGCACCTGGCCCGGGGGATATGTTTCAACCTCGAAAT
GGAAGGATACCGGGTAAGTCACGTGGAGAGCGGCGAAGAGGCCCTGGAGCGCCTTGCCTACGACCGCTTCGCCCTCATCA
TTCTCGATGTCATGCTCCCGGGGATGGACGGATTCGCGGTCTGCGAACGGATCCGCACCATGGACAGCCGCGTGCCGGTG
CTGATCCTGACCGCCCGTTCCGATGAGGGGGCACGGGTCACGGGGCTCCAAAGCGGCGCCGACGACTACCTCACCAAGCC
TTTCAGCCTGAACGAGTTTCTCTTAAGGGTCGGCGGGATGCTGCGGCGCTCCTCCTGGTACCGGCCGGAACCGGTGGAGG
AAGCCTACCGGTTCGGCGACAACGAAGTATTCCTCCTCTCCTATCACGCCCGGACCGCCCAGGGCGAAATCGATCTGACG
GAACTGGAGGTAAAGATGCTCTCCCTTTTCTTCCAGCGGGAGGGAGAGGCGATCAGCCGCCGGGAGATCCTGGAAAACGT
CTGGGGATACACCTCCGACACCGAAACCCGGACCCTCGACAACTTCATCGTACGGCTCCGGAAATACTTCGAGCCGAACC
CGGCCAGACCGATCTACTTTCACACCGTTCGGGGACTGGGCTACCGCTTTAGCAGGAAAGGGAGCGAGATAGTGAGATCG
TGA

Upstream 100 bases:

>100_bases
AGGAGCACGGCGGAACCGTAACCGCCACGAGCGCGGGTATCGGAGAGGGGACTAGCTTCATCATCAGCCTCCCCCTCCCC
CGCCGTAAGAGGGGCTCCCC

Downstream 100 bases:

>100_bases
AGGAGTAGGATACAAAAGGAGAAAAGGCCGGGTGACGCAAAGTCATCCGGCCTTTTTACTATCTCGCTACTTACTATCTT
ACTATCTCGCTAGATTCCCG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTEEKPHILLVEDEMHLARGICFNLEMEGYRVSHVESGEEALERLAYDRFALIILDVMLPGMDGFAVCERIRTMDSRVPV
LILTARSDEGARVTGLQSGADDYLTKPFSLNEFLLRVGGMLRRSSWYRPEPVEEAYRFGDNEVFLLSYHARTAQGEIDLT
ELEVKMLSLFFQREGEAISRREILENVWGYTSDTETRTLDNFIVRLRKYFEPNPARPIYFHTVRGLGYRFSRKGSEIVRS

Sequences:

>Translated_240_residues
MTEEKPHILLVEDEMHLARGICFNLEMEGYRVSHVESGEEALERLAYDRFALIILDVMLPGMDGFAVCERIRTMDSRVPV
LILTARSDEGARVTGLQSGADDYLTKPFSLNEFLLRVGGMLRRSSWYRPEPVEEAYRFGDNEVFLLSYHARTAQGEIDLT
ELEVKMLSLFFQREGEAISRREILENVWGYTSDTETRTLDNFIVRLRKYFEPNPARPIYFHTVRGLGYRFSRKGSEIVRS
>Mature_239_residues
TEEKPHILLVEDEMHLARGICFNLEMEGYRVSHVESGEEALERLAYDRFALIILDVMLPGMDGFAVCERIRTMDSRVPVL
ILTARSDEGARVTGLQSGADDYLTKPFSLNEFLLRVGGMLRRSSWYRPEPVEEAYRFGDNEVFLLSYHARTAQGEIDLTE
LEVKMLSLFFQREGEAISRREILENVWGYTSDTETRTLDNFIVRLRKYFEPNPARPIYFHTVRGLGYRFSRKGSEIVRS

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=37.280701754386, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=38.2222222222222, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=36, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=34.1772151898734, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=33.7837837837838, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=36.6071428571429, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1788394, Length=240, Percent_Identity=32.0833333333333, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=33.6206896551724, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=32.5991189427313, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=32.579185520362, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787229, Length=212, Percent_Identity=34.4339622641509, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=34.1991341991342, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=28.6995515695067, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693140, Length=243, Percent_Identity=27.9835390946502, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790437, Length=140, Percent_Identity=32.8571428571429, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1790299, Length=105, Percent_Identity=36.1904761904762, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788550, Length=121, Percent_Identity=30.5785123966942, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788905, Length=125, Percent_Identity=32, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788713, Length=108, Percent_Identity=32.4074074074074, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789149, Length=166, Percent_Identity=31.3253012048193, Blast_Score=60, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322000, Length=114, Percent_Identity=31.5789473684211, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27802; Mature: 27671

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEEKPHILLVEDEMHLARGICFNLEMEGYRVSHVESGEEALERLAYDRFALIILDVMLP
CCCCCCCEEEEECCHHHHCCEEEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHC
GMDGFAVCERIRTMDSRVPVLILTARSDEGARVTGLQSGADDYLTKPFSLNEFLLRVGGM
CCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCCCHHHHCCCCCHHHHHHHHHHH
LRRSSWYRPEPVEEAYRFGDNEVFLLSYHARTAQGEIDLTELEVKMLSLFFQREGEAISR
HHHCCCCCCCCHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHH
REILENVWGYTSDTETRTLDNFIVRLRKYFEPNPARPIYFHTVRGLGYRFSRKGSEIVRS
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCEECCCCCHHHHCC
>Mature Secondary Structure 
TEEKPHILLVEDEMHLARGICFNLEMEGYRVSHVESGEEALERLAYDRFALIILDVMLP
CCCCCCEEEEECCHHHHCCEEEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHC
GMDGFAVCERIRTMDSRVPVLILTARSDEGARVTGLQSGADDYLTKPFSLNEFLLRVGGM
CCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCCCHHHHCCCCCHHHHHHHHHHH
LRRSSWYRPEPVEEAYRFGDNEVFLLSYHARTAQGEIDLTELEVKMLSLFFQREGEAISR
HHHCCCCCCCCHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHH
REILENVWGYTSDTETRTLDNFIVRLRKYFEPNPARPIYFHTVRGLGYRFSRKGSEIVRS
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCEECCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]