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The map label for this gene is mtnN [H]

Identifier: 78222488

GI number: 78222488

Start: 1435253

End: 1436047

Strand: Reverse

Name: mtnN [H]

Synonym: Gmet_1274

Alternate gene names: 78222488

Gene position: 1436047-1435253 (Counterclockwise)

Preceding gene: 78222505

Following gene: 78222481

Centisome position: 35.92

GC content: 61.76

Gene sequence:

>795_bases
TTGCCGCACGGGGTTCCCTTTGGTACAGTGCCGCCCATGGGTACTATCGGACTTATTGCGGCAATGCCCGACGAGATACG
GCCTTTCCTCCGACTGGCAAGCCCTGCGGCACGCTTGCACGGCGGGAGATTCCCCATTTGGCGGTTGCGGGTCGGCAATG
ATGACATCGTTCTCGTGGAATCAGGGATGGGGATCGACAGGGCGACAGCGGCAACCGATGCGCTCGTGGCTGCAGCCTCG
CCGGTCGCCATCCTTTCCTTCGGTTTTGGTGGTGCCGCGTTGCCCGGCCTCAAAGTGGGAGACCTGGCGGTGGGAATGAC
AAGCTGGTTTGCCGGTACGGAGGGGATTGTCCTCCGCAGGGGAATCGACCGGAACCTGGCCGAAAAGCTGGCCGAAGAGC
TCAACAGGATATGCAACGGGGTCACCCGGGGTGAAATTATCACATCCGCCCGGATTCTCAAGAAGGGCGATCTGGCTCAT
TCACTCCCGAACGGAATATCCTCGCCGATTCTCGACATGGAAACGGCCGCAGTGGCCGAGGCAGCCCACCGGCGCGGGAT
ACCAATCGTGGCCCTTCGCGCCATCAGCGACGACGCTGAAGAAGAGCTTTCCTTCTCCCTCGACGAATTCACCGACGATG
ACATGGCAATCCGCCCCCGGAAAGTGCTGGCGACCATCGCCCGAAAGCCCTGGATCATCCCCCAGCTTCTGAGGCTTGCC
CGCAACTCCCGCATCGCCGGCAAACGGCTCGCCCAGGGGGTTCTGGCAACCGCAGAGTTTCTTTCCCGCGGATAA

Upstream 100 bases:

>100_bases
TGGGGGCAAAAGATTTGCTGCTGCTAGGATTGTGTCCCTTCGGCAGGTGGGACGGATAACGCTACCTCAAAGGCCGTAGC
GTGTCAAGGGATGAAATGCG

Downstream 100 bases:

>100_bases
GGGGCGGGACAGTCCCTCCGTCTATCCCTTGCGGGCCGATGCGACAGACCAGGGGAAGTCCCTCAGATGTTCCGCCAGTT
CCTCCTTACGGTATCGGTTA

Product: purine phosphorylase family protein 1

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MPHGVPFGTVPPMGTIGLIAAMPDEIRPFLRLASPAARLHGGRFPIWRLRVGNDDIVLVESGMGIDRATAATDALVAAAS
PVAILSFGFGGAALPGLKVGDLAVGMTSWFAGTEGIVLRRGIDRNLAEKLAEELNRICNGVTRGEIITSARILKKGDLAH
SLPNGISSPILDMETAAVAEAAHRRGIPIVALRAISDDAEEELSFSLDEFTDDDMAIRPRKVLATIARKPWIIPQLLRLA
RNSRIAGKRLAQGVLATAEFLSRG

Sequences:

>Translated_264_residues
MPHGVPFGTVPPMGTIGLIAAMPDEIRPFLRLASPAARLHGGRFPIWRLRVGNDDIVLVESGMGIDRATAATDALVAAAS
PVAILSFGFGGAALPGLKVGDLAVGMTSWFAGTEGIVLRRGIDRNLAEKLAEELNRICNGVTRGEIITSARILKKGDLAH
SLPNGISSPILDMETAAVAEAAHRRGIPIVALRAISDDAEEELSFSLDEFTDDDMAIRPRKVLATIARKPWIIPQLLRLA
RNSRIAGKRLAQGVLATAEFLSRG
>Mature_263_residues
PHGVPFGTVPPMGTIGLIAAMPDEIRPFLRLASPAARLHGGRFPIWRLRVGNDDIVLVESGMGIDRATAATDALVAAASP
VAILSFGFGGAALPGLKVGDLAVGMTSWFAGTEGIVLRRGIDRNLAEKLAEELNRICNGVTRGEIITSARILKKGDLAHS
LPNGISSPILDMETAAVAEAAHRRGIPIVALRAISDDAEEELSFSLDEFTDDDMAIRPRKVLATIARKPWIIPQLLRLAR
NSRIAGKRLAQGVLATAEFLSRG

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 28063; Mature: 27932

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHGVPFGTVPPMGTIGLIAAMPDEIRPFLRLASPAARLHGGRFPIWRLRVGNDDIVLVE
CCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCHHHHCCCCCCEEEEEECCCCEEEEE
SGMGIDRATAATDALVAAASPVAILSFGFGGAALPGLKVGDLAVGMTSWFAGTEGIVLRR
CCCCCCHHHHHHHHHHHHCCCHHEEEECCCCCCCCCCEECHHHHHHHHHHCCCCCEEEEC
GIDRNLAEKLAEELNRICNGVTRGEIITSARILKKGDLAHSLPNGISSPILDMETAAVAE
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHH
AAHRRGIPIVALRAISDDAEEELSFSLDEFTDDDMAIRPRKVLATIARKPWIIPQLLRLA
HHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
RNSRIAGKRLAQGVLATAEFLSRG
HCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PHGVPFGTVPPMGTIGLIAAMPDEIRPFLRLASPAARLHGGRFPIWRLRVGNDDIVLVE
CCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCHHHHCCCCCCEEEEEECCCCEEEEE
SGMGIDRATAATDALVAAASPVAILSFGFGGAALPGLKVGDLAVGMTSWFAGTEGIVLRR
CCCCCCHHHHHHHHHHHHCCCHHEEEECCCCCCCCCCEECHHHHHHHHHHCCCCCEEEEC
GIDRNLAEKLAEELNRICNGVTRGEIITSARILKKGDLAHSLPNGISSPILDMETAAVAE
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHH
AAHRRGIPIVALRAISDDAEEELSFSLDEFTDDDMAIRPRKVLATIARKPWIIPQLLRLA
HHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
RNSRIAGKRLAQGVLATAEFLSRG
HCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]