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The map label for this gene is yhaO [H]

Identifier: 78222438

GI number: 78222438

Start: 1378512

End: 1379642

Strand: Direct

Name: yhaO [H]

Synonym: Gmet_1223

Alternate gene names: 78222438

Gene position: 1378512-1379642 (Clockwise)

Preceding gene: 78222437

Following gene: 78222439

Centisome position: 34.49

GC content: 63.04

Gene sequence:

>1131_bases
ATGACCATCCGTATTCTCCATACCGCCGATCTCCATTTGGGCTCTTCCCTGAAGAATTTTGGGGAATTGGCCCGGGAACG
CCGGCGCGATTTTCTCAAGACCTTCGACCGGATCGTGAACCTCGCCATCAAGCGCGAAGTCGATTGCCTCCTGGTGGCTG
GCGATCTCTTTGATGCCACACAGGTGGACGCCGAAACCGTGGGGCGCGTTCAGGACGGCTTTGAACGCCTCTCGGGACGT
GGCATCAGCGTGGTTCTTATCCCCGGTACCCACGACAACGTGGTCTCAGCCGAAAGCGTCTACAACCGTACTACCTTCGC
CGGCGCCCATATCCTGAAAGATCCTGTGGTGACGGACCCCTTCGCGCTGGAAATTCGGGGGGCGACGGTCCATTTCTACG
GGTTCGCCTACCGCTCCGACCGCTCCCGGGAGGCCTTGGAATCGATGCGACGCCGCGAGGGAGGGGGGATTCACGTGGGG
CTCCTCCACGGCTCTCTCAAGGGAAGCCCCGAGTGGGAAATGCGGAAGAAGGATATCCCGTTTACGACGGCGGAACTGGC
GGCACTGGGGCTCGACTATATCGCCCTCGGCCACTATCACAACGTGGGGTGCCTGGAGGATCAGGGACGGGTCGTTGCCT
GCTATCCCGGCTCCCCCGAGGGAAAGAAGTTCGGCGAGAACGGCGAGCGCCACGTCCTCATTGTCGAGGTGGGGGAGGGG
AGCGCAGTTGTCGAGAAGGTGCCGGTGCAGAGCCGCATCATGGACGAGTTGACGGTTGACGCCTCCCTCTTCCCCGAGGC
GGGTGCCCTGGAGGGAGAACTTGCGCGGCTCGCCTCTCCTGATCTCATTGCCCGCATCCGGCTCGCGGGCACCGTGGAGG
ACCCCCTCGACATCGCGAATCTGGCGGGCCGGCTCCAGGGGACGTACGCCTGGCTCGAGCTTCTGGACGAGACCGAGATC
TACAACAGCGACCATGTGAAGCGGATGGAACGGGAGGACTCGATCCGGGGGCTCTTCATCCGGAAGGTCCATGCCCGGTT
CGAGAAAGCGGAATCCGAGGCCGAGCAGGAACTCTGCCGCGATGCCCTGAAGCTCGTCATGGGCCGCTTCATGCGAGGGG
GGGGAGACTGA

Upstream 100 bases:

>100_bases
TCGCCGATTCTCGGGCCGAAGGGGAACCGGGAATTTCTGATCCATCTGATTAAACGGCACATTTCCCCTAATTCATAACC
TCAAACCCATCACATCGATT

Downstream 100 bases:

>100_bases
TGCTCTGGATAACCTCCGTGCAACTCCCCGCCTTTGGCCGTTTCGGGGGGGAGGAGTTCACCTTCCGCCGGGGTATGAAC
CTGGTGTGCGGCAAGAACGA

Product: metallophosphoesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MTIRILHTADLHLGSSLKNFGELARERRRDFLKTFDRIVNLAIKREVDCLLVAGDLFDATQVDAETVGRVQDGFERLSGR
GISVVLIPGTHDNVVSAESVYNRTTFAGAHILKDPVVTDPFALEIRGATVHFYGFAYRSDRSREALESMRRREGGGIHVG
LLHGSLKGSPEWEMRKKDIPFTTAELAALGLDYIALGHYHNVGCLEDQGRVVACYPGSPEGKKFGENGERHVLIVEVGEG
SAVVEKVPVQSRIMDELTVDASLFPEAGALEGELARLASPDLIARIRLAGTVEDPLDIANLAGRLQGTYAWLELLDETEI
YNSDHVKRMEREDSIRGLFIRKVHARFEKAESEAEQELCRDALKLVMGRFMRGGGD

Sequences:

>Translated_376_residues
MTIRILHTADLHLGSSLKNFGELARERRRDFLKTFDRIVNLAIKREVDCLLVAGDLFDATQVDAETVGRVQDGFERLSGR
GISVVLIPGTHDNVVSAESVYNRTTFAGAHILKDPVVTDPFALEIRGATVHFYGFAYRSDRSREALESMRRREGGGIHVG
LLHGSLKGSPEWEMRKKDIPFTTAELAALGLDYIALGHYHNVGCLEDQGRVVACYPGSPEGKKFGENGERHVLIVEVGEG
SAVVEKVPVQSRIMDELTVDASLFPEAGALEGELARLASPDLIARIRLAGTVEDPLDIANLAGRLQGTYAWLELLDETEI
YNSDHVKRMEREDSIRGLFIRKVHARFEKAESEAEQELCRDALKLVMGRFMRGGGD
>Mature_375_residues
TIRILHTADLHLGSSLKNFGELARERRRDFLKTFDRIVNLAIKREVDCLLVAGDLFDATQVDAETVGRVQDGFERLSGRG
ISVVLIPGTHDNVVSAESVYNRTTFAGAHILKDPVVTDPFALEIRGATVHFYGFAYRSDRSREALESMRRREGGGIHVGL
LHGSLKGSPEWEMRKKDIPFTTAELAALGLDYIALGHYHNVGCLEDQGRVVACYPGSPEGKKFGENGERHVLIVEVGEGS
AVVEKVPVQSRIMDELTVDASLFPEAGALEGELARLASPDLIARIRLAGTVEDPLDIANLAGRLQGTYAWLELLDETEIY
NSDHVKRMEREDSIRGLFIRKVHARFEKAESEAEQELCRDALKLVMGRFMRGGGD

Specific function: Sbccd Cleaves DNA Hairpin Structures. These Structures Can Inhibit DNA Replication And Are Intermediates In Certain DNA Recombination Reactions. The Complex Acts As A 3'->5' Double Strand Exonuclease That Can Open Hairpins. It Also Has A 5' Single-Strand

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallophosphoesterase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR014576 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 41624; Mature: 41493

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRILHTADLHLGSSLKNFGELARERRRDFLKTFDRIVNLAIKREVDCLLVAGDLFDAT
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCH
QVDAETVGRVQDGFERLSGRGISVVLIPGTHDNVVSAESVYNRTTFAGAHILKDPVVTDP
HCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHCCCCCCCC
FALEIRGATVHFYGFAYRSDRSREALESMRRREGGGIHVGLLHGSLKGSPEWEMRKKDIP
EEEEEECCEEEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHCCCCC
FTTAELAALGLDYIALGHYHNVGCLEDQGRVVACYPGSPEGKKFGENGERHVLIVEVGEG
CCHHHHHHHHHHHEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEEECCC
SAVVEKVPVQSRIMDELTVDASLFPEAGALEGELARLASPDLIARIRLAGTVEDPLDIAN
CEEHHHCCHHHHHHHHHHCCHHCCCCCCCCCHHHHHHCCCCHHEEEEECCCCCCHHHHHH
LAGRLQGTYAWLELLDETEIYNSDHVKRMEREDSIRGLFIRKVHARFEKAESEAEQELCR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DALKLVMGRFMRGGGD
HHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TIRILHTADLHLGSSLKNFGELARERRRDFLKTFDRIVNLAIKREVDCLLVAGDLFDAT
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCH
QVDAETVGRVQDGFERLSGRGISVVLIPGTHDNVVSAESVYNRTTFAGAHILKDPVVTDP
HCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHCCCCCCCC
FALEIRGATVHFYGFAYRSDRSREALESMRRREGGGIHVGLLHGSLKGSPEWEMRKKDIP
EEEEEECCEEEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHCCCCC
FTTAELAALGLDYIALGHYHNVGCLEDQGRVVACYPGSPEGKKFGENGERHVLIVEVGEG
CCHHHHHHHHHHHEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEEECCC
SAVVEKVPVQSRIMDELTVDASLFPEAGALEGELARLASPDLIARIRLAGTVEDPLDIAN
CEEHHHCCHHHHHHHHHHCCHHCCCCCCCCCHHHHHHCCCCHHEEEEECCCCCCHHHHHH
LAGRLQGTYAWLELLDETEIYNSDHVKRMEREDSIRGLFIRKVHARFEKAESEAEQELCR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DALKLVMGRFMRGGGD
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]