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The map label for this gene is corA [H]

Identifier: 78222404

GI number: 78222404

Start: 1320817

End: 1321914

Strand: Direct

Name: corA [H]

Synonym: Gmet_1189

Alternate gene names: 78222404

Gene position: 1320817-1321914 (Clockwise)

Preceding gene: 78222403

Following gene: 78222410

Centisome position: 33.04

GC content: 58.29

Gene sequence:

>1098_bases
ATGCCCGGAGGCGCTAACGCAACCCCCATGAGGAACAAGCTCGTCACAAAGCGTTCCGCCAAGGCGGGGCTTCCCCCCGG
CACCCTCGTTCACATCGGCGAACGGCACCGCGAAGCGGCCCGGGTCTCCATTATCGCCTATGACGAGAAAGGCGTTTACG
AACAGGCTTCCGACGACCTTGCCGCCTGTTTCCCTCTGCGCAACCAGCCGGAAGTCAGCTGGATCAATGTGGAGGGAATC
CACAGCATCGAACTCCTTCAGAAACTGGGCGAATGTTACGGCATCCACCCTCTGGTGCTGGAAGACATTCTCAATACCGA
CCAGCGCCCGAAGCGGGAGGACTACGGCGCCTACCTCTTCATCGTTCTCAAGATGCTCTCCCTCAAAAACGGCAACAAAG
GGGTGGCTGCCGAACAGATGAGTCTCATTCTGGGTGAGAACTTCGTGCTCTCCTTCCAGGAGGGGCTTGCGGGGGATCCC
TTCGACCCGGTTCGTGAGCGGCTGCGGGCCGGTCGTGGGAAAATCCGCTCCCTGGGAGCCGATTATCTCGTCTACTCCCT
CATCGACGCCATTATTGACAACTACTTCGTTATCCTCGAAAGCCTGGCGGAGCGGATCGAGCGGCTCGAAGAAGAGCTGG
TGGCCAATCCGGTGCGCGAAACCGTCGGCAGGCTCCACATCCTCAAGCGGGAAGTGATTTTTCTGCGCAAATCAATCTGG
CCCCTCCGCGAGGTGATCAGCGGCCTCGAACGGCGTGAATCGTCCCTCGTCCGCGAAGAGACCGCCATCTACCTGCGCGA
TGTCTATGACCATACCGTGCAGATCATTGACACCGTGGAAACCTTCCGCGATATCCTTTCGGGGCTCCTCGACATCTACC
TTTCCACCCTCAGCAACCGCACCAACGAAGTCATGAAGGTGCTGACCATCATCGCCACCCTCTTCATGCCCCTTACCTTC
ATTGCCGGTCTCTACGGCATGAACTTCCACTATATGCCCGAGCTCAACTGGCGCTGGGGCTACCCCGCCGTGCTCATCCT
CATGCTTCTGGTGATCGGGGGGATGCTCGTCTTTTTCAGAAGGAAGAAATGGATATAG

Upstream 100 bases:

>100_bases
TGCGCAAGCGCAAGGTAGCCATCGCCTGCGGTGAAGGTATGGTGCACGGAAACTATCTTCACCTTGAAGACCAGTTCGGC
ATCGGGCTCAAGCCATTCTG

Downstream 100 bases:

>100_bases
GCCGGCCCCCTATTTGTTCGACTTGAGTTGATCCGGGCTCGTGATACGTACTCCCTGATGGTCGAGAAGCTCGCCGGTGT
CGCGCCACAGCTTCGAGACG

Product: magnesium/cobalt transporter CorA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MPGGANATPMRNKLVTKRSAKAGLPPGTLVHIGERHREAARVSIIAYDEKGVYEQASDDLAACFPLRNQPEVSWINVEGI
HSIELLQKLGECYGIHPLVLEDILNTDQRPKREDYGAYLFIVLKMLSLKNGNKGVAAEQMSLILGENFVLSFQEGLAGDP
FDPVRERLRAGRGKIRSLGADYLVYSLIDAIIDNYFVILESLAERIERLEEELVANPVRETVGRLHILKREVIFLRKSIW
PLREVISGLERRESSLVREETAIYLRDVYDHTVQIIDTVETFRDILSGLLDIYLSTLSNRTNEVMKVLTIIATLFMPLTF
IAGLYGMNFHYMPELNWRWGYPAVLILMLLVIGGMLVFFRRKKWI

Sequences:

>Translated_365_residues
MPGGANATPMRNKLVTKRSAKAGLPPGTLVHIGERHREAARVSIIAYDEKGVYEQASDDLAACFPLRNQPEVSWINVEGI
HSIELLQKLGECYGIHPLVLEDILNTDQRPKREDYGAYLFIVLKMLSLKNGNKGVAAEQMSLILGENFVLSFQEGLAGDP
FDPVRERLRAGRGKIRSLGADYLVYSLIDAIIDNYFVILESLAERIERLEEELVANPVRETVGRLHILKREVIFLRKSIW
PLREVISGLERRESSLVREETAIYLRDVYDHTVQIIDTVETFRDILSGLLDIYLSTLSNRTNEVMKVLTIIATLFMPLTF
IAGLYGMNFHYMPELNWRWGYPAVLILMLLVIGGMLVFFRRKKWI
>Mature_364_residues
PGGANATPMRNKLVTKRSAKAGLPPGTLVHIGERHREAARVSIIAYDEKGVYEQASDDLAACFPLRNQPEVSWINVEGIH
SIELLQKLGECYGIHPLVLEDILNTDQRPKREDYGAYLFIVLKMLSLKNGNKGVAAEQMSLILGENFVLSFQEGLAGDPF
DPVRERLRAGRGKIRSLGADYLVYSLIDAIIDNYFVILESLAERIERLEEELVANPVRETVGRLHILKREVIFLRKSIWP
LREVISGLERRESSLVREETAIYLRDVYDHTVQIIDTVETFRDILSGLLDIYLSTLSNRTNEVMKVLTIIATLFMPLTFI
AGLYGMNFHYMPELNWRWGYPAVLILMLLVIGGMLVFFRRKKWI

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI1787604, Length=205, Percent_Identity=24.390243902439, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI2367297, Length=138, Percent_Identity=28.9855072463768, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 41574; Mature: 41443

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGGANATPMRNKLVTKRSAKAGLPPGTLVHIGERHREAARVSIIAYDEKGVYEQASDDL
CCCCCCCCCHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHEEEEEEECCCCCHHHHCCCH
AACFPLRNQPEVSWINVEGIHSIELLQKLGECYGIHPLVLEDILNTDQRPKREDYGAYLF
HHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHH
IVLKMLSLKNGNKGVAAEQMSLILGENFVLSFQEGLAGDPFDPVRERLRAGRGKIRSLGA
HHHHHHHCCCCCCCCHHHHHHHHHCCCHHEEHHHCCCCCCCHHHHHHHHHCCHHHHHHHH
DYLVYSLIDAIIDNYFVILESLAERIERLEEELVANPVRETVGRLHILKREVIFLRKSIW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLREVISGLERRESSLVREETAIYLRDVYDHTVQIIDTVETFRDILSGLLDIYLSTLSNR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TNEVMKVLTIIATLFMPLTFIAGLYGMNFHYMPELNWRWGYPAVLILMLLVIGGMLVFFR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RKKWI
HHCCC
>Mature Secondary Structure 
PGGANATPMRNKLVTKRSAKAGLPPGTLVHIGERHREAARVSIIAYDEKGVYEQASDDL
CCCCCCCCHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHEEEEEEECCCCCHHHHCCCH
AACFPLRNQPEVSWINVEGIHSIELLQKLGECYGIHPLVLEDILNTDQRPKREDYGAYLF
HHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHH
IVLKMLSLKNGNKGVAAEQMSLILGENFVLSFQEGLAGDPFDPVRERLRAGRGKIRSLGA
HHHHHHHCCCCCCCCHHHHHHHHHCCCHHEEHHHCCCCCCCHHHHHHHHHCCHHHHHHHH
DYLVYSLIDAIIDNYFVILESLAERIERLEEELVANPVRETVGRLHILKREVIFLRKSIW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLREVISGLERRESSLVREETAIYLRDVYDHTVQIIDTVETFRDILSGLLDIYLSTLSNR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TNEVMKVLTIIATLFMPLTFIAGLYGMNFHYMPELNWRWGYPAVLILMLLVIGGMLVFFR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RKKWI
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]