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The map label for this gene is hypA [H]

Identifier: 78188514

GI number: 78188514

Start: 640287

End: 640703

Strand: Reverse

Name: hypA [H]

Synonym: Cag_0536

Alternate gene names: 78188514

Gene position: 640703-640287 (Counterclockwise)

Preceding gene: 78188515

Following gene: 78188513

Centisome position: 24.91

GC content: 41.97

Gene sequence:

>417_bases
ATGTTAATAAGTGGTATAAGAATTGCTCAATGCCTCTTATTAGTCAACAATTGTAAATATTCCCCTGCCAATACCATGCA
CGAAATGAGCATTGCACTCTCTATTGTAGAGGCTGTAGAAGAGCAAGCCCGAAAAGAGGGTGCTCAAAAAATTATTGCTC
TTGAATTAGTGGTGGGTAAGCTTGCAGCCATTCAAGTTGAATCGCTCACTTTTTGCTTTGCAGCCGCCGCAAAAGGTACG
CTTGCAGAACATGCTGCATTGATAATTGAAGAGCCTGAAGGTATTGGAAAATGCGAAGAGTGCGGAAAAGAGTTTCCCGT
GAATTTTTATTATGCTGAATGCCCGCAATGTCGGTCGCTACGCATCAACATTGTTTCGGGTGAAGAGTTTCGGATTAAAG
CAATGGAGATTTGTTGA

Upstream 100 bases:

>100_bases
AACCAACGTCACCTATCAACAGCAAAGGGCATTGCCCATTTTTCACCACCCCGCCATTTTAAAAAGCGGGGTGTTTTTTT
GTACGTCCCTTTATTTCTTT

Downstream 100 bases:

>100_bases
TTATGGATTATGAATTATGGATTTTTGATCGTTGTTTTAAACTTGGATTTGTATAAATAATCTACAGAAACATTCATAAT
TCATAATTCACCATTTATCA

Product: hydrogenase expression/synthesis, HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MLISGIRIAQCLLLVNNCKYSPANTMHEMSIALSIVEAVEEQARKEGAQKIIALELVVGKLAAIQVESLTFCFAAAAKGT
LAEHAALIIEEPEGIGKCEECGKEFPVNFYYAECPQCRSLRINIVSGEEFRIKAMEIC

Sequences:

>Translated_138_residues
MLISGIRIAQCLLLVNNCKYSPANTMHEMSIALSIVEAVEEQARKEGAQKIIALELVVGKLAAIQVESLTFCFAAAAKGT
LAEHAALIIEEPEGIGKCEECGKEFPVNFYYAECPQCRSLRINIVSGEEFRIKAMEIC
>Mature_138_residues
MLISGIRIAQCLLLVNNCKYSPANTMHEMSIALSIVEAVEEQARKEGAQKIIALELVVGKLAAIQVESLTFCFAAAAKGT
LAEHAALIIEEPEGIGKCEECGKEFPVNFYYAECPQCRSLRINIVSGEEFRIKAMEIC

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

Organism=Escherichia coli, GI1789081, Length=113, Percent_Identity=31.858407079646, Blast_Score=70, Evalue=5e-14,
Organism=Escherichia coli, GI1789365, Length=112, Percent_Identity=26.7857142857143, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR020538 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 15095; Mature: 15095

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
5.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
8.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLISGIRIAQCLLLVNNCKYSPANTMHEMSIALSIVEAVEEQARKEGAQKIIALELVVGK
CCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAIQVESLTFCFAAAAKGTLAEHAALIIEEPEGIGKCEECGKEFPVNFYYAECPQCRSL
HHHEEHHHHHHHHHHHHCCCHHHHEEEEEECCCCCCCHHHCCCCCCCEEEECCCCCCCCE
RINIVSGEEFRIKAMEIC
EEEEECCCCEEEEEEECC
>Mature Secondary Structure
MLISGIRIAQCLLLVNNCKYSPANTMHEMSIALSIVEAVEEQARKEGAQKIIALELVVGK
CCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAIQVESLTFCFAAAAKGTLAEHAALIIEEPEGIGKCEECGKEFPVNFYYAECPQCRSL
HHHEEHHHHHHHHHHHHCCCHHHHEEEEEECCCCCCCHHHCCCCCCCEEEECCCCCCCCE
RINIVSGEEFRIKAMEIC
EEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA