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The map label for this gene is hypB [H]

Identifier: 78188512

GI number: 78188512

Start: 637748

End: 638575

Strand: Reverse

Name: hypB [H]

Synonym: Cag_0534

Alternate gene names: 78188512

Gene position: 638575-637748 (Counterclockwise)

Preceding gene: 78188513

Following gene: 78188511

Centisome position: 24.83

GC content: 47.1

Gene sequence:

>828_bases
ATGTGCGATAGTTGCGGTTGCTCGGGAGATGGTGGTATGGTAATACGAAAACCAAGTCAAGCGGAAGAGCATCATCACGA
ACATGCTCACCATAGTCATCACCATGCAGATCATCACCACTCTCACGAGCATGGAGAGGAGCATAGTCATTCGCATTCTC
ACGAACATAGCCATGCACGTAAAGTGGTGGTTGAGCAAGATGTGTTGTTGAAAAACAATCTGCTTGCTGAGCGTAATCGT
GGTTATTTTGATGCTCGTTCGATTTATGCTATCAATTTGCTGAGTTCGCCGGGTTCGGGGAAAACCTCGTTGTTAGAGCG
GCTGATTCCTGCGCTGCAACAGCATTTTCCCGTTGCTGTTATTGAGGGCGATCAGCAAACCACTAACGATGCTGATCGGC
TCCATGCGCTTGGTATTTCCGCCATTCAAATCAACACAGGCTCTGGCTGCCATCTTGATGCTGATATGGTGAATCGCGCA
ATCAAGCAGCTTGAGCTAAAAGATCATTCCCTGCTTTGCATTGAAAACGTTGGCAATTTAGTGTGCCCTGCCATGTTTGA
CCTTGGCGAAGCGTTGAAAATTGTGGTGATTAGCGTTACCGAAGGGGAGGATAAGCCCTTGAAATATCCCGCAATGTTTC
ATGCGGCTGATGTGTGCATTGTCAATAAAATTGATTTGCTGCCATACGTTGATTTTAATGTGGAGCGTTGCAAGGAGTAT
GCTATGCAGGTGAATCACCATTTGCAATGGTTTGAAGTGTCGGCAAAAAGTGGTGATGGGCTTGCGGCGTTGCAGGAATG
GCTTGAGCATCAGGTTGTGCTCCATTGA

Upstream 100 bases:

>100_bases
CATTGTTTTTGATCCGAAAGAGCGAAATGTTAGTCGGTTTGCATGGGAGCGTGTTTGAATGATATTCCTTTAACCTTCAA
TATTATAAGGATTTACTTTT

Downstream 100 bases:

>100_bases
ACAGGTTTCTGCGTCAGATGCAGCGCCAGCGTTTATTAATTAACGGGATTGTGCAGGGCGTTGGCTTCCGTCCCTTTGTT
TATCGTTTAGCTATTGAGCA

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MCDSCGCSGDGGMVIRKPSQAEEHHHEHAHHSHHHADHHHSHEHGEEHSHSHSHEHSHARKVVVEQDVLLKNNLLAERNR
GYFDARSIYAINLLSSPGSGKTSLLERLIPALQQHFPVAVIEGDQQTTNDADRLHALGISAIQINTGSGCHLDADMVNRA
IKQLELKDHSLLCIENVGNLVCPAMFDLGEALKIVVISVTEGEDKPLKYPAMFHAADVCIVNKIDLLPYVDFNVERCKEY
AMQVNHHLQWFEVSAKSGDGLAALQEWLEHQVVLH

Sequences:

>Translated_275_residues
MCDSCGCSGDGGMVIRKPSQAEEHHHEHAHHSHHHADHHHSHEHGEEHSHSHSHEHSHARKVVVEQDVLLKNNLLAERNR
GYFDARSIYAINLLSSPGSGKTSLLERLIPALQQHFPVAVIEGDQQTTNDADRLHALGISAIQINTGSGCHLDADMVNRA
IKQLELKDHSLLCIENVGNLVCPAMFDLGEALKIVVISVTEGEDKPLKYPAMFHAADVCIVNKIDLLPYVDFNVERCKEY
AMQVNHHLQWFEVSAKSGDGLAALQEWLEHQVVLH
>Mature_275_residues
MCDSCGCSGDGGMVIRKPSQAEEHHHEHAHHSHHHADHHHSHEHGEEHSHSHSHEHSHARKVVVEQDVLLKNNLLAERNR
GYFDARSIYAINLLSSPGSGKTSLLERLIPALQQHFPVAVIEGDQQTTNDADRLHALGISAIQINTGSGCHLDADMVNRA
IKQLELKDHSLLCIENVGNLVCPAMFDLGEALKIVVISVTEGEDKPLKYPAMFHAADVCIVNKIDLLPYVDFNVERCKEY
AMQVNHHLQWFEVSAKSGDGLAALQEWLEHQVVLH

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=292, Percent_Identity=48.2876712328767, Blast_Score=261, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 30661; Mature: 30661

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCDSCGCSGDGGMVIRKPSQAEEHHHEHAHHSHHHADHHHSHEHGEEHSHSHSHEHSHAR
CCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCHHHHHHH
KVVVEQDVLLKNNLLAERNRGYFDARSIYAINLLSSPGSGKTSLLERLIPALQQHFPVAV
HHHHHHHHHHHHCHHHHCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCEEE
IEGDQQTTNDADRLHALGISAIQINTGSGCHLDADMVNRAIKQLELKDHSLLCIENVGNL
EECCCCCCCHHHHHHHHCEEEEEEECCCCCEECHHHHHHHHHHHHCCCCCEEEEHHCCCH
VCPAMFDLGEALKIVVISVTEGEDKPLKYPAMFHAADVCIVNKIDLLPYVDFNVERCKEY
HHHHHHHHCCEEEEEEEEEECCCCCCCCCCHHHHHHCEEEEECCCCCEECCCCHHHHHHH
AMQVNHHLQWFEVSAKSGDGLAALQEWLEHQVVLH
HHHHHCCEEEEEEECCCCCCHHHHHHHHHHCEECC
>Mature Secondary Structure
MCDSCGCSGDGGMVIRKPSQAEEHHHEHAHHSHHHADHHHSHEHGEEHSHSHSHEHSHAR
CCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCHHHHHHH
KVVVEQDVLLKNNLLAERNRGYFDARSIYAINLLSSPGSGKTSLLERLIPALQQHFPVAV
HHHHHHHHHHHHCHHHHCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCEEE
IEGDQQTTNDADRLHALGISAIQINTGSGCHLDADMVNRAIKQLELKDHSLLCIENVGNL
EECCCCCCCHHHHHHHHCEEEEEEECCCCCEECHHHHHHHHHHHHCCCCCEEEEHHCCCH
VCPAMFDLGEALKIVVISVTEGEDKPLKYPAMFHAADVCIVNKIDLLPYVDFNVERCKEY
HHHHHHHHCCEEEEEEEEEECCCCCCCCCCHHHHHHCEEEEECCCCCEECCCCHHHHHHH
AMQVNHHLQWFEVSAKSGDGLAALQEWLEHQVVLH
HHHHHCCEEEEEEECCCCCCHHHHHHHHHHCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]