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The map label for this gene is sigW [H]

Identifier: 78188451

GI number: 78188451

Start: 553311

End: 553871

Strand: Reverse

Name: sigW [H]

Synonym: Cag_0473

Alternate gene names: 78188451

Gene position: 553871-553311 (Counterclockwise)

Preceding gene: 78188452

Following gene: 78188450

Centisome position: 21.53

GC content: 45.1

Gene sequence:

>561_bases
ATGACTCGCAACAACAACAAGGAAGCTGCTTTTAAACGCCTTGTAGAGCAGCACATGGAGATGGTAGTTAACACGTGTTA
CCGTTTTGTGATGAACCGTGAAGATGCCGAGGATATTGCACAGGAGGTGTTTATTGAAATGCATCGCTCGCTTGATAGCT
TTCGCGAAGAGTCGAAGCTTTCAACATGGATTTACCGCATTGCCGTTACCAAATCGCTTGACCATCTTCGTTACATGAAA
CGCAAAAAGCGTTTTAGTTCGTTAAAGCGGCTTATTGGCATGGAGGGTGAGGAGGATCCAACCGAAAACTTGCCCGACGT
TTCGCAAGCAACGCCTCACGAAGTAATGGAGCAAGCGCATCGGGCGGAACTGCTACAACGCGCACTTGATAGCTTACCTG
AAGCGCAAAAAGCCGCCTTACTACTAAGCAAGCAAGATGGTTACGGCAATCAAGAAATTGCTGAAATTCTTGGCACATCA
ATTAGCGCTGTTGAATCGCTGATTCATCGCGCTAAAAAAACTCTCCACAAAAAATTGTATGACAAATACAGCAAAGAATA
A

Upstream 100 bases:

>100_bases
TTTTCGGCTTCCCCATCGTCAAACCCGCAAGAACACAAATCCAAAATTTCCTTCTGCCTCCAACAGCATTGGCAAACCAT
TCTTCACCCTGCAACCTTAC

Downstream 100 bases:

>100_bases
GCGGCAGAATAGTTCCACACAAAAGAATAATAACGCACAAGTTTTTATAAAAGCTATCGTCATAAGAGAAGAACCAATAA
CACTATGAAACAGCATCGTC

Product: sigma-24 (FecI-like)

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MTRNNNKEAAFKRLVEQHMEMVVNTCYRFVMNREDAEDIAQEVFIEMHRSLDSFREESKLSTWIYRIAVTKSLDHLRYMK
RKKRFSSLKRLIGMEGEEDPTENLPDVSQATPHEVMEQAHRAELLQRALDSLPEAQKAALLLSKQDGYGNQEIAEILGTS
ISAVESLIHRAKKTLHKKLYDKYSKE

Sequences:

>Translated_186_residues
MTRNNNKEAAFKRLVEQHMEMVVNTCYRFVMNREDAEDIAQEVFIEMHRSLDSFREESKLSTWIYRIAVTKSLDHLRYMK
RKKRFSSLKRLIGMEGEEDPTENLPDVSQATPHEVMEQAHRAELLQRALDSLPEAQKAALLLSKQDGYGNQEIAEILGTS
ISAVESLIHRAKKTLHKKLYDKYSKE
>Mature_185_residues
TRNNNKEAAFKRLVEQHMEMVVNTCYRFVMNREDAEDIAQEVFIEMHRSLDSFREESKLSTWIYRIAVTKSLDHLRYMKR
KKRFSSLKRLIGMEGEEDPTENLPDVSQATPHEVMEQAHRAELLQRALDSLPEAQKAALLLSKQDGYGNQEIAEILGTSI
SAVESLIHRAKKTLHKKLYDKYSKE

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=171, Percent_Identity=32.1637426900585, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21669; Mature: 21538

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRNNNKEAAFKRLVEQHMEMVVNTCYRFVMNREDAEDIAQEVFIEMHRSLDSFREESKL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
STWIYRIAVTKSLDHLRYMKRKKRFSSLKRLIGMEGEEDPTENLPDVSQATPHEVMEQAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
RAELLQRALDSLPEAQKAALLLSKQDGYGNQEIAEILGTSISAVESLIHRAKKTLHKKLY
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
DKYSKE
HHHCCC
>Mature Secondary Structure 
TRNNNKEAAFKRLVEQHMEMVVNTCYRFVMNREDAEDIAQEVFIEMHRSLDSFREESKL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
STWIYRIAVTKSLDHLRYMKRKKRFSSLKRLIGMEGEEDPTENLPDVSQATPHEVMEQAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
RAELLQRALDSLPEAQKAALLLSKQDGYGNQEIAEILGTSISAVESLIHRAKKTLHKKLY
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
DKYSKE
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]