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The map label for this gene is frr

Identifier: 78188304

GI number: 78188304

Start: 364260

End: 364820

Strand: Reverse

Name: frr

Synonym: Cag_0326

Alternate gene names: 78188304

Gene position: 364820-364260 (Counterclockwise)

Preceding gene: 78188305

Following gene: 78188299

Centisome position: 14.18

GC content: 42.25

Gene sequence:

>561_bases
ATGAGCGTCAAAGATGTTGCTCAAAAAATTGAGCCAAAAATGAAGAAATGCCTTGAGGCATTTCAACACGAAATTACTAC
CATTCGAACAGGCAAAGCCACCACAACCTTGCTTGACCGCGTTAAAGTTGAAGCGTATGGGCAACAAATGCCACTCAAAC
AGGTGGGTAATGTAAGCGTGCAAGATGCCCACACGTTGATGGTGCAAGTGTGGGATAAATCTATGGTATCGGCTACTGAA
AAAGCTATTCGCGATGCCAACCTTGGCTTAAATCCTGCGGCTGAAGGGCAAAGCATTCGCGTGAGCATTCCCCCGCTTAC
CGAAGAGCGTCGTAAAGAGTTTGTGAAGCTCACTAAAAAATTTGGTGAGGACTCAAAAGTTTCGTTACGCAATCTTCGCC
GCGATATGATTCAAGACATTGAAAAGCTTGAAAAAGCTAAAGCCGTTAGCGAAGATGAAAAAAACAAAGGCAAAAAAGAT
GCTGATGATTTGCTCCATAAGTATGAAAAGCTGCTTATGGATATGATTACTGCTAAAGAAAAAGAGATTATGGCTGTTTA
A

Upstream 100 bases:

>100_bases
GGTCGTGTTGAACGCTTTAACAAGCGCTTTGCTAAAAAAGCACAAGCTTAAGAATGTAGTGGCGCTTTTCTAAGCAATCA
TCAAACCTATCAAGCAAGTT

Downstream 100 bases:

>100_bases
GCTTTTTTTTCGCCAAGCTCGTTTTACAAGAAAAGCCGGATGTTCTCCGGCTTTTTGCGTTTTTGGGGGGAAATAAAGAA
CCCCGCCTCAAGAGGCGGGG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSVKDVAQKIEPKMKKCLEAFQHEITTIRTGKATTTLLDRVKVEAYGQQMPLKQVGNVSVQDAHTLMVQVWDKSMVSATE
KAIRDANLGLNPAAEGQSIRVSIPPLTEERRKEFVKLTKKFGEDSKVSLRNLRRDMIQDIEKLEKAKAVSEDEKNKGKKD
ADDLLHKYEKLLMDMITAKEKEIMAV

Sequences:

>Translated_186_residues
MSVKDVAQKIEPKMKKCLEAFQHEITTIRTGKATTTLLDRVKVEAYGQQMPLKQVGNVSVQDAHTLMVQVWDKSMVSATE
KAIRDANLGLNPAAEGQSIRVSIPPLTEERRKEFVKLTKKFGEDSKVSLRNLRRDMIQDIEKLEKAKAVSEDEKNKGKKD
ADDLLHKYEKLLMDMITAKEKEIMAV
>Mature_185_residues
SVKDVAQKIEPKMKKCLEAFQHEITTIRTGKATTTLLDRVKVEAYGQQMPLKQVGNVSVQDAHTLMVQVWDKSMVSATEK
AIRDANLGLNPAAEGQSIRVSIPPLTEERRKEFVKLTKKFGEDSKVSLRNLRRDMIQDIEKLEKAKAVSEDEKNKGKKDA
DDLLHKYEKLLMDMITAKEKEIMAV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=150, Percent_Identity=32.6666666666667, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI291042689, Length=117, Percent_Identity=35.8974358974359, Blast_Score=64, Evalue=6e-11,
Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=42.3076923076923, Blast_Score=156, Evalue=1e-39,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_CHLCH (Q3ATS6)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_378642.1
- ProteinModelPortal:   Q3ATS6
- SMR:   Q3ATS6
- STRING:   Q3ATS6
- GeneID:   3748046
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_0326
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   CEATTIR
- ProtClustDB:   PRK00083
- BioCyc:   CCHL340177:CAG_0326-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 21097; Mature: 20966

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKDVAQKIEPKMKKCLEAFQHEITTIRTGKATTTLLDRVKVEAYGQQMPLKQVGNVSV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCH
QDAHTLMVQVWDKSMVSATEKAIRDANLGLNPAAEGQSIRVSIPPLTEERRKEFVKLTKK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
FGEDSKVSLRNLRRDMIQDIEKLEKAKAVSEDEKNKGKKDADDLLHKYEKLLMDMITAKE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
KEIMAV
HHHHCC
>Mature Secondary Structure 
SVKDVAQKIEPKMKKCLEAFQHEITTIRTGKATTTLLDRVKVEAYGQQMPLKQVGNVSV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCH
QDAHTLMVQVWDKSMVSATEKAIRDANLGLNPAAEGQSIRVSIPPLTEERRKEFVKLTKK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
FGEDSKVSLRNLRRDMIQDIEKLEKAKAVSEDEKNKGKKDADDLLHKYEKLLMDMITAKE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
KEIMAV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA