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The map label for this gene is xseA

Identifier: 78188299

GI number: 78188299

Start: 356170

End: 357393

Strand: Reverse

Name: xseA

Synonym: Cag_0321

Alternate gene names: 78188299

Gene position: 357393-356170 (Counterclockwise)

Preceding gene: 78188304

Following gene: 78188284

Centisome position: 13.9

GC content: 46.49

Gene sequence:

>1224_bases
ATGGAAGCAATCAATGCAATGGATGCACTTTCCGTTACCGAACTAACGGCTCACATTAAAAGTGAACTGGAATCATTATT
CCCCTTTGTTCGCGTAAGAGGTGAAATTTCAAACTGTAAGCAACATAGTTCAGGACATATTTATCTCACGCTTAAAGATA
GTGGCGCACAATTACCAGCGGTTATTTGGAAAAGCACCGCTTCACTCTTAAGCATACGCCCAAAAGATGGCATGGAGGTT
GTTGCCGAGGGGCGCTTAGAGCTTTATCCACCTTCGGGGCGCTACCAGCTTATTTGCCGCCATGTAGCTCAAGCGGGAGT
AGGGGCATTGCAGCAAGCCTTTGCGGAGTTGGTGCAAAAACTTGCCGCTTTGGGCTATTTCGACGAGAATCGAAAAAAAA
CCTTGCCGACGATACCAACTACCATTGGCATCATTACTTCGCCTACAGGCGCCGTTATTGAAGATATGAGTAAAGTGCTC
GCTCGCCGTTTTCCAGCAGCTCGCATAGCGCTCTATCCCGTTAAAGTGCAAGGCGCAGGTGCGGCAGAAGAAATTGCACA
AGCGTTAGATTTTTTTAACCACACCAAAAAGAAGCAATGGAAACCTCAGGTGATTATTGTGGCGCGAGGTGGTGGCTCAT
TAGAGGATTTGCAACCCTTTAACGAAGAAATTATGGCACACGCCATTTACCGCTCAGCAATTCCAGTGATAAGCGCGGTG
GGGCATGAAACCGATATTACCATTGCCGACATGGTGGCAGATGTGCGTGCAGGCACTCCCTCCATTGCTGCCGAGTTAGT
AGTACCCGATAGCGCACAAGTGCTTCGCGATGTTGAGCAAATGGTTGCATATGCCCAACAGATACTTAATAATAAGATAG
AGGGGGCTGAACGGGAATTGCATTCGTTGTGCAACAGCTACGCCTTTAATCGTCCAATACTAAAAATGCAGCAATGCTAT
GAGAACCTTGATCGCTTTGAGGCAAGCATGATGCGCAGTGTGGAAACTACCTATCGTCAGCAAATACAGCGTTGCACAGC
CTCTATTCAGCAGCTTAATTTGTTGGATTACCACAAAACGCTTGAGCGAGGTTATGCGCTTATTAAAAAGAATGGAAGAT
TTGTTACTTCAGCAAAAGCTTTGCAACCAAATGACACCATTGAGTTACTCTTACACGATGGAGTGCGCAAAGCCTCAGTT
AAGCCTCCTGATGCCTTTGCTTAA

Upstream 100 bases:

>100_bases
TTTTTTCTTTATGTACAACTCCTCTCAAAAAACCTTACAACAAAAATACATACAAGCTTTTTAAAAATAGCAATTGCCTT
TTTTGGGCAAAGAAGGAGCC

Downstream 100 bases:

>100_bases
AGAGTGTGCGAACTAACTCCAAATCTTCGGCGGTATTAACGCCAGGTTGATCATCGTGCGTTACCATACAGCGAATACGG
TAGCCATGCTCAAGTAAGCG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MEAINAMDALSVTELTAHIKSELESLFPFVRVRGEISNCKQHSSGHIYLTLKDSGAQLPAVIWKSTASLLSIRPKDGMEV
VAEGRLELYPPSGRYQLICRHVAQAGVGALQQAFAELVQKLAALGYFDENRKKTLPTIPTTIGIITSPTGAVIEDMSKVL
ARRFPAARIALYPVKVQGAGAAEEIAQALDFFNHTKKKQWKPQVIIVARGGGSLEDLQPFNEEIMAHAIYRSAIPVISAV
GHETDITIADMVADVRAGTPSIAAELVVPDSAQVLRDVEQMVAYAQQILNNKIEGAERELHSLCNSYAFNRPILKMQQCY
ENLDRFEASMMRSVETTYRQQIQRCTASIQQLNLLDYHKTLERGYALIKKNGRFVTSAKALQPNDTIELLLHDGVRKASV
KPPDAFA

Sequences:

>Translated_407_residues
MEAINAMDALSVTELTAHIKSELESLFPFVRVRGEISNCKQHSSGHIYLTLKDSGAQLPAVIWKSTASLLSIRPKDGMEV
VAEGRLELYPPSGRYQLICRHVAQAGVGALQQAFAELVQKLAALGYFDENRKKTLPTIPTTIGIITSPTGAVIEDMSKVL
ARRFPAARIALYPVKVQGAGAAEEIAQALDFFNHTKKKQWKPQVIIVARGGGSLEDLQPFNEEIMAHAIYRSAIPVISAV
GHETDITIADMVADVRAGTPSIAAELVVPDSAQVLRDVEQMVAYAQQILNNKIEGAERELHSLCNSYAFNRPILKMQQCY
ENLDRFEASMMRSVETTYRQQIQRCTASIQQLNLLDYHKTLERGYALIKKNGRFVTSAKALQPNDTIELLLHDGVRKASV
KPPDAFA
>Mature_407_residues
MEAINAMDALSVTELTAHIKSELESLFPFVRVRGEISNCKQHSSGHIYLTLKDSGAQLPAVIWKSTASLLSIRPKDGMEV
VAEGRLELYPPSGRYQLICRHVAQAGVGALQQAFAELVQKLAALGYFDENRKKTLPTIPTTIGIITSPTGAVIEDMSKVL
ARRFPAARIALYPVKVQGAGAAEEIAQALDFFNHTKKKQWKPQVIIVARGGGSLEDLQPFNEEIMAHAIYRSAIPVISAV
GHETDITIADMVADVRAGTPSIAAELVVPDSAQVLRDVEQMVAYAQQILNNKIEGAERELHSLCNSYAFNRPILKMQQCY
ENLDRFEASMMRSVETTYRQQIQRCTASIQQLNLLDYHKTLERGYALIKKNGRFVTSAKALQPNDTIELLLHDGVRKASV
KPPDAFA

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=397, Percent_Identity=35.264483627204, Blast_Score=230, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 44909; Mature: 44909

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAINAMDALSVTELTAHIKSELESLFPFVRVRGEISNCKQHSSGHIYLTLKDSGAQLPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEECCCCCCCHH
VIWKSTASLLSIRPKDGMEVVAEGRLELYPPSGRYQLICRHVAQAGVGALQQAFAELVQK
HHHHHHHHHHEECCCCCCHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAALGYFDENRKKTLPTIPTTIGIITSPTGAVIEDMSKVLARRFPAARIALYPVKVQGAG
HHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCC
AAEEIAQALDFFNHTKKKQWKPQVIIVARGGGSLEDLQPFNEEIMAHAIYRSAIPVISAV
CHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHC
GHETDITIADMVADVRAGTPSIAAELVVPDSAQVLRDVEQMVAYAQQILNNKIEGAEREL
CCCCCCHHHHHHHHHHCCCCHHEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
HSLCNSYAFNRPILKMQQCYENLDRFEASMMRSVETTYRQQIQRCTASIQQLNLLDYHKT
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGYALIKKNGRFVTSAKALQPNDTIELLLHDGVRKASVKPPDAFA
HHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHCCCHHCCCCCCCCCC
>Mature Secondary Structure
MEAINAMDALSVTELTAHIKSELESLFPFVRVRGEISNCKQHSSGHIYLTLKDSGAQLPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEECCCCCCCHH
VIWKSTASLLSIRPKDGMEVVAEGRLELYPPSGRYQLICRHVAQAGVGALQQAFAELVQK
HHHHHHHHHHEECCCCCCHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAALGYFDENRKKTLPTIPTTIGIITSPTGAVIEDMSKVLARRFPAARIALYPVKVQGAG
HHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCC
AAEEIAQALDFFNHTKKKQWKPQVIIVARGGGSLEDLQPFNEEIMAHAIYRSAIPVISAV
CHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHC
GHETDITIADMVADVRAGTPSIAAELVVPDSAQVLRDVEQMVAYAQQILNNKIEGAEREL
CCCCCCHHHHHHHHHHCCCCHHEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
HSLCNSYAFNRPILKMQQCYENLDRFEASMMRSVETTYRQQIQRCTASIQQLNLLDYHKT
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGYALIKKNGRFVTSAKALQPNDTIELLLHDGVRKASVKPPDAFA
HHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]