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The map label for this gene is tadA [H]

Identifier: 78188173

GI number: 78188173

Start: 217771

End: 218232

Strand: Reverse

Name: tadA [H]

Synonym: Cag_0190

Alternate gene names: 78188173

Gene position: 218232-217771 (Counterclockwise)

Preceding gene: 78188179

Following gene: 78188170

Centisome position: 8.48

GC content: 46.32

Gene sequence:

>462_bases
ATGATTGATTTCAACACCTTTATGAGTGCCGCCTTACGTGAAGCCATTAAAGCCTACGAGCAACGCGAAGTACCCGTTGG
GGCTGTAGTGCTGGATAGCAACGGGCACATTATTGGCAGAGGGCACAATCAAGTAGAAACTTTGCACGATGCCACGGCTC
ACGCCGAAATGATTGCCCTTACCGCCGCAATGGCAACACTTGGCAACAAATATCTTGACGATTGCACCTTGGCGGTTACT
ATGGAACCATGCCCCATGTGTGCAGGGGCAATTGTTAATGCAAAAGTGGGACGGGTAATTTTTGGTGCCTACGATTCTAA
AATGGGGGCATGTGGCACAGTACTCAATATTACAGGCAACCGAGTATTAAACCATCAACCTGAAGTGTTTGGCGGAATTA
TGGAACACAAATGCCAAGAGCTTTTGCAAAGCTTTTTTAAATCGTTACGACAGCAAAAGTAA

Upstream 100 bases:

>100_bases
CTGTAAACAACCGCAAAAAACGTATGTTGGGTATTGTGAAAAATAAAGCTTTGTTTTTTCAAGCAACAAGCACATTCCGC
ACCAACTAAAGAAATGCCGC

Downstream 100 bases:

>100_bases
TTCTACATTATTATCCATCATCCCGTAAAATGGTGCGTAACGAGTTGGCTAAATGTGCCACAATATCTTGCGCCACCCCA
CTACTTGCGGAAGGTTGCTG

Product: cytosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MIDFNTFMSAALREAIKAYEQREVPVGAVVLDSNGHIIGRGHNQVETLHDATAHAEMIALTAAMATLGNKYLDDCTLAVT
MEPCPMCAGAIVNAKVGRVIFGAYDSKMGACGTVLNITGNRVLNHQPEVFGGIMEHKCQELLQSFFKSLRQQK

Sequences:

>Translated_153_residues
MIDFNTFMSAALREAIKAYEQREVPVGAVVLDSNGHIIGRGHNQVETLHDATAHAEMIALTAAMATLGNKYLDDCTLAVT
MEPCPMCAGAIVNAKVGRVIFGAYDSKMGACGTVLNITGNRVLNHQPEVFGGIMEHKCQELLQSFFKSLRQQK
>Mature_153_residues
MIDFNTFMSAALREAIKAYEQREVPVGAVVLDSNGHIIGRGHNQVETLHDATAHAEMIALTAAMATLGNKYLDDCTLAVT
MEPCPMCAGAIVNAKVGRVIFGAYDSKMGACGTVLNITGNRVLNHQPEVFGGIMEHKCQELLQSFFKSLRQQK

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=149, Percent_Identity=32.8859060402685, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI145693172, Length=146, Percent_Identity=44.5205479452055, Blast_Score=134, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17541138, Length=146, Percent_Identity=32.1917808219178, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17554608, Length=98, Percent_Identity=39.7959183673469, Blast_Score=72, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17555996, Length=97, Percent_Identity=40.2061855670103, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322425, Length=115, Percent_Identity=33.9130434782609, Blast_Score=69, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6325319, Length=143, Percent_Identity=30.0699300699301, Blast_Score=64, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21355527, Length=147, Percent_Identity=34.0136054421769, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16596; Mature: 16596

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFNTFMSAALREAIKAYEQREVPVGAVVLDSNGHIIGRGHNQVETLHDATAHAEMIAL
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHH
TAAMATLGNKYLDDCTLAVTMEPCPMCAGAIVNAKVGRVIFGAYDSKMGACGTVLNITGN
HHHHHHHCCHHHCCEEEEEEECCCCCHHHHHHHHHHCEEEEECCCCCCCCCCEEEECCCC
RVLNHQPEVFGGIMEHKCQELLQSFFKSLRQQK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDFNTFMSAALREAIKAYEQREVPVGAVVLDSNGHIIGRGHNQVETLHDATAHAEMIAL
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHH
TAAMATLGNKYLDDCTLAVTMEPCPMCAGAIVNAKVGRVIFGAYDSKMGACGTVLNITGN
HHHHHHHCCHHHCCEEEEEEECCCCCHHHHHHHHHHCEEEEECCCCCCCCCCEEEECCCC
RVLNHQPEVFGGIMEHKCQELLQSFFKSLRQQK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]