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The map label for this gene is maiA [H]

Identifier: 78067609

GI number: 78067609

Start: 3283012

End: 3283656

Strand: Reverse

Name: maiA [H]

Synonym: Bcep18194_A6140

Alternate gene names: 78067609

Gene position: 3283656-3283012 (Counterclockwise)

Preceding gene: 78067612

Following gene: 78067607

Centisome position: 88.89

GC content: 64.5

Gene sequence:

>645_bases
ATGAAGCTTTACAGCTATTTCCGCAGTTCCGCGTCGTATCGCGTGCGGATCGCCCTGAACCTGAAGCAGCTGCCGTTCGA
CTATGTCCCCGTGCACATGCTGCGCGACGGCGGCGAGCAACTGAAGGACGCGTACCGCGCGCTGAATCCGGATGCGGTCG
TGCCGACACTGATCGACGGCGACGCGACGCTGCAGCAGTCGCTCGCGATCATCGAATATCTCGAGGAAACCCATCCGGAA
CCGGCGTTGCTGCCGAAGCAGCCGGTCGATCGCGCGTATGTGCGCGCGGTCGCGCTGCAGATCGCGTGCGAAATCCATCC
GCTCGACAACCTGCGCGTGCTGAAGTACCTGAAGCACACGCTGCAGGTGCCCGAGGAGGCGAAGAACGCGTGGTACCGGC
ACTGGATCGAGGCGGGCTTCGACACGCTCGAGACGCGTCTCGCGAGCGATCCGCGCACCGGCAAGCTGTGCTTCGGCGAC
ACGCCGACGCTCGCCGACATATGCCTCGTGCCGCAGGTGTTCAATGCGAACCGCTTCTCGATCGACACGACGCGCTATCC
GACGATCCAGCGGATCGTCGACCATGCGTCGACGCTCGATGCGTTCAAGGCCGCCGAACCCGGCGTGCAGCCCGACGCCG
AATGA

Upstream 100 bases:

>100_bases
GCGCGGCGCGGCGCGCTACACTCTGGTTCCCGGCGGTGCGCGCGCCGGCTGCGCCGCGCCCGTGCCGTCGCCGGCCGAAT
ACGACTACGAGAGACATCCC

Downstream 100 bases:

>100_bases
TCGCGGCGCGCCCGGGACTTGCATGACCGGGCGCGCATGAAAAAGGGCGCCCGAAGGCGCCCTGTGCGATGCGTGCCGGC
GGTGTTCAGCCGAGCAGCGC

Product: maleylacetoacetate isomerase

Products: NA

Alternate protein names: MAAI [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MKLYSYFRSSASYRVRIALNLKQLPFDYVPVHMLRDGGEQLKDAYRALNPDAVVPTLIDGDATLQQSLAIIEYLEETHPE
PALLPKQPVDRAYVRAVALQIACEIHPLDNLRVLKYLKHTLQVPEEAKNAWYRHWIEAGFDTLETRLASDPRTGKLCFGD
TPTLADICLVPQVFNANRFSIDTTRYPTIQRIVDHASTLDAFKAAEPGVQPDAE

Sequences:

>Translated_214_residues
MKLYSYFRSSASYRVRIALNLKQLPFDYVPVHMLRDGGEQLKDAYRALNPDAVVPTLIDGDATLQQSLAIIEYLEETHPE
PALLPKQPVDRAYVRAVALQIACEIHPLDNLRVLKYLKHTLQVPEEAKNAWYRHWIEAGFDTLETRLASDPRTGKLCFGD
TPTLADICLVPQVFNANRFSIDTTRYPTIQRIVDHASTLDAFKAAEPGVQPDAE
>Mature_214_residues
MKLYSYFRSSASYRVRIALNLKQLPFDYVPVHMLRDGGEQLKDAYRALNPDAVVPTLIDGDATLQQSLAIIEYLEETHPE
PALLPKQPVDRAYVRAVALQIACEIHPLDNLRVLKYLKHTLQVPEEAKNAWYRHWIEAGFDTLETRLASDPRTGKLCFGD
TPTLADICLVPQVFNANRFSIDTTRYPTIQRIVDHASTLDAFKAAEPGVQPDAE

Specific function: Forms An Equimolar Complex With The RNA Polymerase Holoenzyme (Rnap) But Not With The Core Enzyme. It Is Synthesized Predominantly When Cells Are Exposed To Amino Acid Starvation, At Which Time It Accounts For Over 50% Of The Total Protein Synthesized. It

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI22202624, Length=211, Percent_Identity=51.6587677725119, Blast_Score=196, Evalue=1e-50,
Organism=Homo sapiens, GI22202622, Length=160, Percent_Identity=51.25, Blast_Score=137, Evalue=8e-33,
Organism=Homo sapiens, GI194440732, Length=211, Percent_Identity=40.2843601895735, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17551302, Length=212, Percent_Identity=42.9245283018868, Blast_Score=161, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17510461, Length=211, Percent_Identity=39.8104265402844, Blast_Score=148, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17556142, Length=212, Percent_Identity=41.0377358490566, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24645375, Length=212, Percent_Identity=48.5849056603774, Blast_Score=188, Evalue=2e-48,
Organism=Drosophila melanogaster, GI21355859, Length=212, Percent_Identity=48.5849056603774, Blast_Score=188, Evalue=3e-48,
Organism=Drosophila melanogaster, GI45553325, Length=212, Percent_Identity=48.5849056603774, Blast_Score=188, Evalue=3e-48,
Organism=Drosophila melanogaster, GI21355857, Length=213, Percent_Identity=46.4788732394366, Blast_Score=177, Evalue=4e-45,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1982 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR005955
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =5.2.1.2 [H]

Molecular weight: Translated: 24205; Mature: 24205

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYSYFRSSASYRVRIALNLKQLPFDYVPVHMLRDGGEQLKDAYRALNPDAVVPTLIDG
CCHHHHHHCCCCEEEEEEEEHHHCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEECC
DATLQQSLAIIEYLEETHPEPALLPKQPVDRAYVRAVALQIACEIHPLDNLRVLKYLKHT
CHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHH
LQVPEEAKNAWYRHWIEAGFDTLETRLASDPRTGKLCFGDTPTLADICLVPQVFNANRFS
HCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCEE
IDTTRYPTIQRIVDHASTLDAFKAAEPGVQPDAE
ECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKLYSYFRSSASYRVRIALNLKQLPFDYVPVHMLRDGGEQLKDAYRALNPDAVVPTLIDG
CCHHHHHHCCCCEEEEEEEEHHHCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEECC
DATLQQSLAIIEYLEETHPEPALLPKQPVDRAYVRAVALQIACEIHPLDNLRVLKYLKHT
CHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHH
LQVPEEAKNAWYRHWIEAGFDTLETRLASDPRTGKLCFGDTPTLADICLVPQVFNANRFS
HCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCEE
IDTTRYPTIQRIVDHASTLDAFKAAEPGVQPDAE
ECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]