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The map label for this gene is ybdL [H]

Identifier: 78067022

GI number: 78067022

Start: 2651141

End: 2652313

Strand: Direct

Name: ybdL [H]

Synonym: Bcep18194_A5553

Alternate gene names: 78067022

Gene position: 2651141-2652313 (Clockwise)

Preceding gene: 78067021

Following gene: 78067024

Centisome position: 71.77

GC content: 64.36

Gene sequence:

>1173_bases
ATGAACGCTCCTTCAGACATGCCAACGACTCCCGTTTTCCCCTCGCGCCTGCCGAACGTCGGCACGACGATCTTCACGGT
CATGAGCGCGCTTGCCGCAGAAAAAGGCGCGGTGAACCTCGGCCAGGGCTTTCCGGATTTCGACTGCGATCCGCGCATCG
TCGATGCGGTTGCCACGGCGATGCGCAACGGGCACAACCAGTATCCGCCGATGGCCGGTGTCGCGCCGCTACGGGACGCG
ATCGCAGACAAGATCGCGCAGGTCTACGGCCGGCGTTACGATCCGGCCACCGAAATCACCGTCACGGCCGGCGCGACGCA
GGCATTGCTGACCGCGATCATGTGCACGGTGCATCCGGGTGATGAAGTGATCGTCGTCGAGCCGACCTACGACAGCTACC
TGCCGTCGATCGAACTCGCGGGCGGCAAGCCCGTGTTCGTCACGCTGGAAGCGCCCGACTACGCGATCCCGTTCGACCGT
CTGGCGGCCGCAATCACGCCGAAAACGCGCATGATCCTGATCAACACACCGCATAACCCGACGGGTACCGTGTGGCGCGA
GGCGGACATGCGCAAGCTCGAGGAGATCGTGCGCGGCACCAACGTGCTGATCCTGTCCGACGAGGTCTACGAGCACATGG
TCTATGACGGCGCGCGCCACGAGAGCGTCGCGCGCTATCCGGAACTCGCCGCGCGCAGCTTCATCGTGTCGAGCTTCGGC
AAGACCTATCACGTGACGGGCTGGAAGGTCGGCTATGTCGCGGCGCCTGCCGCGCTGACCGCGGAATTCCGCAAGGTCCA
CCAGTTCAACGTGTTCACGGTGAACACGCCGATGCAGATCGGGCTCGCCGACTATCTGCGCGACCCGGCGCCGTACCTGA
CGCTTGCCGACTTCTACCAGAAGAAGCGCGACTTCTTCCGGGCCGGCCTCGAGCGCACGCGCTTCAAGTTGCTGCCCTGC
ACGGGCACATACTTCCAGTGCGTCGATTATTCGGCGATCAGCGACCAGCCGGAAGCGGAATTCTCGAAGTGGCTCACGTC
GGAGATTGGCGTGGCCGCCATTCCGGTGTCGGCGTTCTATCACGAGCCGCACGAATCGGGCGTCGTCCGATTCTGCTTCG
CGAAGCAGGAAAGCACGCTCGCGTCCGCGCTCGAGCGGCTCGCCCGCCTGTAA

Upstream 100 bases:

>100_bases
CGGCTTCCGGATCGCGCAACCCGCACCGTTTGCCGAGGCCTGCGCGCTCGACGCCACGCCGGCCTGACGCACGCACCACC
ACCCGATTTCGACCGTATCG

Downstream 100 bases:

>100_bases
GACCCGCACGGGCGGCCGCACGCCGCCCTGCGGGAATCGCGCTTACGAGCGCGCGACGCTCGTCGCGTCGATATACGCCT
TGCGCTCGGCCGCCACGCGC

Product: putative aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MNAPSDMPTTPVFPSRLPNVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVATAMRNGHNQYPPMAGVAPLRDA
IADKIAQVYGRRYDPATEITVTAGATQALLTAIMCTVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYAIPFDR
LAAAITPKTRMILINTPHNPTGTVWREADMRKLEEIVRGTNVLILSDEVYEHMVYDGARHESVARYPELAARSFIVSSFG
KTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPMQIGLADYLRDPAPYLTLADFYQKKRDFFRAGLERTRFKLLPC
TGTYFQCVDYSAISDQPEAEFSKWLTSEIGVAAIPVSAFYHEPHESGVVRFCFAKQESTLASALERLARL

Sequences:

>Translated_390_residues
MNAPSDMPTTPVFPSRLPNVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVATAMRNGHNQYPPMAGVAPLRDA
IADKIAQVYGRRYDPATEITVTAGATQALLTAIMCTVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYAIPFDR
LAAAITPKTRMILINTPHNPTGTVWREADMRKLEEIVRGTNVLILSDEVYEHMVYDGARHESVARYPELAARSFIVSSFG
KTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPMQIGLADYLRDPAPYLTLADFYQKKRDFFRAGLERTRFKLLPC
TGTYFQCVDYSAISDQPEAEFSKWLTSEIGVAAIPVSAFYHEPHESGVVRFCFAKQESTLASALERLARL
>Mature_390_residues
MNAPSDMPTTPVFPSRLPNVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVATAMRNGHNQYPPMAGVAPLRDA
IADKIAQVYGRRYDPATEITVTAGATQALLTAIMCTVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYAIPFDR
LAAAITPKTRMILINTPHNPTGTVWREADMRKLEEIVRGTNVLILSDEVYEHMVYDGARHESVARYPELAARSFIVSSFG
KTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPMQIGLADYLRDPAPYLTLADFYQKKRDFFRAGLERTRFKLLPC
TGTYFQCVDYSAISDQPEAEFSKWLTSEIGVAAIPVSAFYHEPHESGVVRFCFAKQESTLASALERLARL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=409, Percent_Identity=33.9853300733496, Blast_Score=231, Evalue=8e-61,
Organism=Homo sapiens, GI169881279, Length=409, Percent_Identity=33.9853300733496, Blast_Score=231, Evalue=8e-61,
Organism=Homo sapiens, GI56713254, Length=401, Percent_Identity=33.4164588528678, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI56713256, Length=401, Percent_Identity=33.4164588528678, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI169881281, Length=408, Percent_Identity=29.656862745098, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI4507369, Length=216, Percent_Identity=27.3148148148148, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1786816, Length=386, Percent_Identity=50.7772020725389, Blast_Score=401, Evalue=1e-113,
Organism=Escherichia coli, GI1788722, Length=379, Percent_Identity=25.8575197889182, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1788627, Length=188, Percent_Identity=32.4468085106383, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787710, Length=297, Percent_Identity=28.956228956229, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71994472, Length=404, Percent_Identity=34.9009900990099, Blast_Score=228, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI71994476, Length=404, Percent_Identity=35.1485148514851, Blast_Score=228, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI17567369, Length=406, Percent_Identity=31.5270935960591, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17567663, Length=203, Percent_Identity=25.615763546798, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=397, Percent_Identity=32.7455919395466, Blast_Score=195, Evalue=1e-50,
Organism=Drosophila melanogaster, GI28573069, Length=411, Percent_Identity=35.5231143552311, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24646114, Length=411, Percent_Identity=35.5231143552311, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI28573067, Length=411, Percent_Identity=35.5231143552311, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI28573065, Length=411, Percent_Identity=35.5231143552311, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI18859735, Length=207, Percent_Identity=28.5024154589372, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42998; Mature: 42998

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPSDMPTTPVFPSRLPNVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVATA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
MRNGHNQYPPMAGVAPLRDAIADKIAQVYGRRYDPATEITVTAGATQALLTAIMCTVHPG
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHEECCC
DEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYAIPFDRLAAAITPKTRMILINTPHNP
CCEEEECCCHHHHCCCEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEEEEECCCCC
TGTVWREADMRKLEEIVRGTNVLILSDEVYEHMVYDGARHESVARYPELAARSFIVSSFG
CCCEECHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
KTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPMQIGLADYLRDPAPYLTLADFYQ
CEEEECCEEEEHEECCHHHHHHHHHHHEEEEEEECCCHHHCHHHHHCCCCCCHHHHHHHH
KKRDFFRAGLERTRFKLLPCTGTYFQCVDYSAISDQPEAEFSKWLTSEIGVAAIPVSAFY
HHHHHHHHHHHHCCEEEEECCCCHHHHCCCHHCCCCCHHHHHHHHHHCCCEEEEEHHHHH
HEPHESGVVRFCFAKQESTLASALERLARL
CCCCCCCEEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNAPSDMPTTPVFPSRLPNVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVATA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
MRNGHNQYPPMAGVAPLRDAIADKIAQVYGRRYDPATEITVTAGATQALLTAIMCTVHPG
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHEECCC
DEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYAIPFDRLAAAITPKTRMILINTPHNP
CCEEEECCCHHHHCCCEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEEEEECCCCC
TGTVWREADMRKLEEIVRGTNVLILSDEVYEHMVYDGARHESVARYPELAARSFIVSSFG
CCCEECHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
KTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPMQIGLADYLRDPAPYLTLADFYQ
CEEEECCEEEEHEECCHHHHHHHHHHHEEEEEEECCCHHHCHHHHHCCCCCCHHHHHHHH
KKRDFFRAGLERTRFKLLPCTGTYFQCVDYSAISDQPEAEFSKWLTSEIGVAAIPVSAFY
HHHHHHHHHHHHCCEEEEECCCCHHHHCCCHHCCCCCHHHHHHHHHHCCCEEEEEHHHHH
HEPHESGVVRFCFAKQESTLASALERLARL
CCCCCCCEEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]