Click here to switch to the map view.

The map label for this gene is acoC [H]

Identifier: 78066607

GI number: 78066607

Start: 2183217

End: 2184332

Strand: Reverse

Name: acoC [H]

Synonym: Bcep18194_A5138

Alternate gene names: 78066607

Gene position: 2184332-2183217 (Counterclockwise)

Preceding gene: 78066608

Following gene: 78066606

Centisome position: 59.13

GC content: 69.35

Gene sequence:

>1116_bases
ATGTCGATTCACATGATCACGATGCCCAAGTGGGGGCTGTCGATGGAGCAGGGGCAGGTCAACGGCTGGTTGAAGGCCCT
CGGCGAACGCGTGACGAAGGGCGATGAAGTGCTCGACGTCGAGACCGACAAGATCTCGTCGGGCGTCGAATGCGCGTTCG
ACGGCACGCTGCGCCGGCAGGTCGCGCAGGAAGGCGAGACGCTGCCGGTCGGCGCGCTGCTCGGCGTCGTCGCGGCCGCC
GATGCGAGCGATGCCGACATCGATGCGGCGATTGCCGATTTCCAGCGCGATTTCGTACCGAGCGCGGCTTCCGACGAAGC
CGCGGGCCCGCAGCCCGAGAAGGCGCAGATCGGCGGCCGAACCGTGCGCTTCCTGAAGCTCGGCGACGGCAGCGGCACGC
CCGCCGTGCTGATCCACGGCTTCGGCGGCGACCTCAACAACTGGTTGTTCAATCACGCGGATCTCGCGGCGCACCGGCCG
GTGTGGGCGCTCGACCTGCCCGGTCACGGCGAGTCGGGCAAGGCGGTCGAGACGGGCAGCCTCGATGAACTGGCCGACGC
GGTGCTTGCGCTGCTCGATGCGAAGGGCATCGACCACGCCCACCTGATCGGCCATTCGATGGGCGGCGCGGTCGCGATGG
CGGCGGCCGAGCGCGCGCCGCAACGTGTCGCGTCGCTGACGCTGATCGCAAGCGCCGGGCTCGGCACCGACATCAACCGC
GCTTACATCGACGGCTTCGTCGCCGGCAACAGCCGCAACACGCTGAAGCCGCACCTCGGCGCGCTGTTCGCGGACAACGC
GCTGGTCACGCGGCAGCTCGTCGAGGATCTCGTCAAGTACAAGCGGCTCGAAGGTGTGCAGGCCGCGCTCGAAAAGATCG
CGAATGCCGCGTTCGACGGCGCCGCACAGCGGCGCGTGTTCCGCGACCGGCTCGCGACGCTTGCGCCGCGCACGCTCGTG
ATCTGGGGCGAGCGCGACCAGGTGATCCCGGCGCAGCACGCGCAGGGTCTGCCTGACGGCGTGCGTGCCGAGGTGATCGC
CGGCAGCGGGCACATGGTGCAGATGGAGGCCGCCGCCGACGTGAACCGCCTGATCGTCGCGTTTCTCGGAGACTGA

Upstream 100 bases:

>100_bases
CCGCATACGCCTGCGCCGTTCGCGAGCGTGCTGGAAGACCTGTATATCCCGTCCGCCGATGCGATTGCGCAGGCGGTCCT
GAAGACGAGGAGCTGACACG

Downstream 100 bases:

>100_bases
CGATGGCCGCCGCGCTCGAACGACCCAGCCTCACGGCGCTCGGCCAGCCGGGCGCGAGAAGCCGCGACAAGCTCGCGCGC
ATTCCGGTGCGCGTCGAGCC

Product: branched-chain alpha-keto acid dehydrogenase subunit E2

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSIHMITMPKWGLSMEQGQVNGWLKALGERVTKGDEVLDVETDKISSGVECAFDGTLRRQVAQEGETLPVGALLGVVAAA
DASDADIDAAIADFQRDFVPSAASDEAAGPQPEKAQIGGRTVRFLKLGDGSGTPAVLIHGFGGDLNNWLFNHADLAAHRP
VWALDLPGHGESGKAVETGSLDELADAVLALLDAKGIDHAHLIGHSMGGAVAMAAAERAPQRVASLTLIASAGLGTDINR
AYIDGFVAGNSRNTLKPHLGALFADNALVTRQLVEDLVKYKRLEGVQAALEKIANAAFDGAAQRRVFRDRLATLAPRTLV
IWGERDQVIPAQHAQGLPDGVRAEVIAGSGHMVQMEAAADVNRLIVAFLGD

Sequences:

>Translated_371_residues
MSIHMITMPKWGLSMEQGQVNGWLKALGERVTKGDEVLDVETDKISSGVECAFDGTLRRQVAQEGETLPVGALLGVVAAA
DASDADIDAAIADFQRDFVPSAASDEAAGPQPEKAQIGGRTVRFLKLGDGSGTPAVLIHGFGGDLNNWLFNHADLAAHRP
VWALDLPGHGESGKAVETGSLDELADAVLALLDAKGIDHAHLIGHSMGGAVAMAAAERAPQRVASLTLIASAGLGTDINR
AYIDGFVAGNSRNTLKPHLGALFADNALVTRQLVEDLVKYKRLEGVQAALEKIANAAFDGAAQRRVFRDRLATLAPRTLV
IWGERDQVIPAQHAQGLPDGVRAEVIAGSGHMVQMEAAADVNRLIVAFLGD
>Mature_370_residues
SIHMITMPKWGLSMEQGQVNGWLKALGERVTKGDEVLDVETDKISSGVECAFDGTLRRQVAQEGETLPVGALLGVVAAAD
ASDADIDAAIADFQRDFVPSAASDEAAGPQPEKAQIGGRTVRFLKLGDGSGTPAVLIHGFGGDLNNWLFNHADLAAHRPV
WALDLPGHGESGKAVETGSLDELADAVLALLDAKGIDHAHLIGHSMGGAVAMAAAERAPQRVASLTLIASAGLGTDINRA
YIDGFVAGNSRNTLKPHLGALFADNALVTRQLVEDLVKYKRLEGVQAALEKIANAAFDGAAQRRVFRDRLATLAPRTLVI
WGERDQVIPAQHAQGLPDGVRAEVIAGSGHMVQMEAAADVNRLIVAFLGD

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI50658087, Length=106, Percent_Identity=33.9622641509434, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87081721, Length=296, Percent_Identity=26.6891891891892, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 38999; Mature: 38867

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIHMITMPKWGLSMEQGQVNGWLKALGERVTKGDEVLDVETDKISSGVECAFDGTLRRQ
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCEEEECHHHHHH
VAQEGETLPVGALLGVVAAADASDADIDAAIADFQRDFVPSAASDEAAGPQPEKAQIGGR
HHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCC
TVRFLKLGDGSGTPAVLIHGFGGDLNNWLFNHADLAAHRPVWALDLPGHGESGKAVETGS
EEEEEEECCCCCCCEEEEECCCCCHHHHHHCCCHHHHCCCEEEEECCCCCCCCCEEECCC
LDELADAVLALLDAKGIDHAHLIGHSMGGAVAMAAAERAPQRVASLTLIASAGLGTDINR
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCH
AYIDGFVAGNSRNTLKPHLGALFADNALVTRQLVEDLVKYKRLEGVQAALEKIANAAFDG
HHHEEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
AAQRRVFRDRLATLAPRTLVIWGERDQVIPAQHAQGLPDGVRAEVIAGSGHMVQMEAAAD
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHCCCCCCCEEEEEECCCCEEEEHHHCC
VNRLIVAFLGD
CCCEEEEEECC
>Mature Secondary Structure 
SIHMITMPKWGLSMEQGQVNGWLKALGERVTKGDEVLDVETDKISSGVECAFDGTLRRQ
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCEEEECHHHHHH
VAQEGETLPVGALLGVVAAADASDADIDAAIADFQRDFVPSAASDEAAGPQPEKAQIGGR
HHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCC
TVRFLKLGDGSGTPAVLIHGFGGDLNNWLFNHADLAAHRPVWALDLPGHGESGKAVETGS
EEEEEEECCCCCCCEEEEECCCCCHHHHHHCCCHHHHCCCEEEEECCCCCCCCCEEECCC
LDELADAVLALLDAKGIDHAHLIGHSMGGAVAMAAAERAPQRVASLTLIASAGLGTDINR
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCH
AYIDGFVAGNSRNTLKPHLGALFADNALVTRQLVEDLVKYKRLEGVQAALEKIANAAFDG
HHHEEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
AAQRRVFRDRLATLAPRTLVIWGERDQVIPAQHAQGLPDGVRAEVIAGSGHMVQMEAAAD
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHCCCCCCCEEEEEECCCCEEEEHHHCC
VNRLIVAFLGD
CCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7813883 [H]