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The map label for this gene is dnaX [H]

Identifier: 78066597

GI number: 78066597

Start: 2170627

End: 2173002

Strand: Reverse

Name: dnaX [H]

Synonym: Bcep18194_A5128

Alternate gene names: 78066597

Gene position: 2173002-2170627 (Counterclockwise)

Preceding gene: 78066606

Following gene: 78066596

Centisome position: 58.82

GC content: 70.24

Gene sequence:

>2376_bases
ATGACCTATCAAGTTCTCGCACGCAAGTGGCGTCCGAAGGATTTCGCTTCGCTCGTCGGCCAGGAGCACGTCGTCAGGGC
GCTTACGCACGCGCTCGACGGCGGGCGTCTCCATCACGCCTATCTGTTTACCGGAACCCGCGGTGTCGGCAAGACGACGC
TGTCGCGGATCTTCGCCAAGGCACTCAACTGTGAAACCGGCGTCACGTCGCAGCCGTGCGGCGTGTGTCGAGCCTGTCGC
GAGATCGACGAAGGGCGTTTCGTCGATTACGTCGAGATGGATGCCGCGAGCAACCGCGGCGTCGATGAAATGGCCGCGCT
GCTCGAGCGCGCGGTGTACGCGCCCGTCGATGCGCGCTTCAAGGTCTACATGATCGACGAAGTGCACATGCTGACGAATC
ACGCGTTCAACGCGATGCTGAAGACGCTCGAAGAGCCGCCGCCGCACGTCAAGTTCATCCTCGCGACGACCGATCCGCAG
AAAATTCCCGTCACCGTGCTGTCGCGCTGCCTGCAGTTCAACCTGAAGCAGATGCCGGCCGGGCACATCGTGTCGCATCT
CGAACGGATCCTCGGCGAAGAGCAGATCACGTTCGAGCCGCAGGCACTGCGCCTGCTCGCGCGCGCTGCGCAGGGCAGCA
TGCGCGATGCGCTGTCGCTCACCGACCAGGCGATCGCCTATTCGGCGAACGAGGTGACCGAGTCGGCCGTGTCGGGCATG
CTCGGCGCGCTCGACCAGACTTACATGGTGCGTCTGCTCGACGCGCTTGCCGCAGGCGGCGGCCCGGAAATCCTCGCGAT
TGCCGACGAGATGTCGCTGCGCAGCCTGTCGTTCTCGACCGCGCTTCAGGATCTCGCGAGCCTGCTGCACCGGATCGCGT
GGGCGCAGTTCGCGCCGGGCTCGGTGCTCGACGAATGGCCCGAAGCAGGCGACCTGCGCCGCTTCGCCGACACGTTAAGC
CCCGAGCAGGTCCAGTTGTTCTATCAGATCGCGACGGTCGGTCGCGCCGAGCTCGGCCTGGCGCCGGACGAGTACGCCGG
TTTCACGATGACGCTGCTGCGGATGCTCGCGTTCGAGCCGGCGGTTGCTGCCGGCAGTGCGACGGGCGGCCAGCCGTCCG
TGCCGCGTGCGGTGCCGGGCCCGCGCGTCGCGGCAGCATCGGTTGCGGCGGCGAAGCCGGCATCGGCTGCACCTGCCGAA
GCAGTGCGGCAGCAGGCCGTTGCACCGGCAGCGCCCGCGGTACCCGCGGCACCGGTTGTGCATACAGCGCCGGTGCAGTC
CGGCGACGAAACGGACCGGCCGGCCGTAAAGCCGGCTGCCGTCCAGGCCGCCGCGCCGGCCCCGGTTGACGCGCCAGTCA
TCGAAACGCCGCAGCCGCAGACGGCTGCAGCACCGCAAGCGGAGCCGGCCGGCGATACCCCGGCGCCTGTCCGCAAGGAG
CCCGAGTCGCCTGCCGTCGTTGAGCAGCGAAGCGACGAGCCGGCTGCGCCGTCCGAACCGACGCCGCGCGCTGCGCCGCC
TGAGCCCGCTGCACGTCCGGCGGCGCGTTCCGGAGGCGCTGCCGCCGCGCTCGACGTGTTGCGCAATGCGGGGATGCGCG
TGTCGTCCGACCGCGGGCGCGCAGGTGCCGCCCCAGCCGCTAAACCGGCAGCCCAGCCGGCTGCCGAGAAACCGGTCGCA
CCGCGTCCCGCTGCCGTACAGGTGCCGACGCCGCGCGCCGCGGCCCGTGCGCCGCAGGCAGCCGATTCGCGTCAGGCCTC
GCCGCCGTGGGAAGACATCCCGCCCGACGACTACGTGCCCCTCAGCGCCGACGAAATGTTCGGCGGCCCGCCCGACGATG
GCTTCGTGCCGGTGTTCGACAGCGGCCCCGACGATGTGCGCGTGACGCCGAGGCCGGCGGAAACCCGTCCGTCCGCACCG
GTCGACACGCGTCCGTTGCCGCCCGCGATCGCACTCGATCCGGTCGGCTTCGACGGCGAATGGCCGGCACTGGCTGCACG
GCTGCCGCTCAAGGGCGTCGCGTACCAGCTTGCGTTCAACAGCGAACTGACGGCCGTCGATGCGACGACGTTGAAACTTT
CCGTGCCGGTGCCGCAATATGCGGACGCCGCGCAGGTGGCGAAGCTGAAGGCCGCGCTGGCCGATGCGCTCGGCAAGCCG
GTCGAGGTGGCCGTCGAAGTCGGGCCCGCACGGCGTACGGCGGCGGCGCTCGATGCGGCCGCGCGCGCGGCACGCCAGCG
CGAGGCCGAGCAGGAGATTCACGGCGATCCGTTCGTCCAGCAGCTCGTGCGCGATTTCGGTGCGCGCATCGTCGAGGGTT
CGGTGCGCCCGCTTGCCGACGCGGCGCCGGACGGCCCGCCGCCGACGCTGCATTGA

Upstream 100 bases:

>100_bases
TTTTTATTTCCGCATCACTCTCCGTTTTGCCTGCCCGTTGCCTGTCTTCCGCACCGTTTCGCGTGTCGGCGCGACGCAGC
GTTACTGATACAATTTCCCG

Downstream 100 bases:

>100_bases
ACTGACCGCCCCGCGACAGGCACAATCACGCCCACACATTGGCCGGCACGCGCCGCGTGCCGGTTTTCACACGATCAAGA
AGGAGTATTCCCATGTTGAA

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 791; Mature: 790

Protein sequence:

>791_residues
MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR
EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ
KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM
LGALDQTYMVRLLDALAAGGGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEWPEAGDLRRFADTLS
PEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEPAVAAGSATGGQPSVPRAVPGPRVAAASVAAAKPASAAPAE
AVRQQAVAPAAPAVPAAPVVHTAPVQSGDETDRPAVKPAAVQAAAPAPVDAPVIETPQPQTAAAPQAEPAGDTPAPVRKE
PESPAVVEQRSDEPAAPSEPTPRAAPPEPAARPAARSGGAAAALDVLRNAGMRVSSDRGRAGAAPAAKPAAQPAAEKPVA
PRPAAVQVPTPRAAARAPQAADSRQASPPWEDIPPDDYVPLSADEMFGGPPDDGFVPVFDSGPDDVRVTPRPAETRPSAP
VDTRPLPPAIALDPVGFDGEWPALAARLPLKGVAYQLAFNSELTAVDATTLKLSVPVPQYADAAQVAKLKAALADALGKP
VEVAVEVGPARRTAAALDAAARAARQREAEQEIHGDPFVQQLVRDFGARIVEGSVRPLADAAPDGPPPTLH

Sequences:

>Translated_791_residues
MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR
EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ
KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM
LGALDQTYMVRLLDALAAGGGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEWPEAGDLRRFADTLS
PEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEPAVAAGSATGGQPSVPRAVPGPRVAAASVAAAKPASAAPAE
AVRQQAVAPAAPAVPAAPVVHTAPVQSGDETDRPAVKPAAVQAAAPAPVDAPVIETPQPQTAAAPQAEPAGDTPAPVRKE
PESPAVVEQRSDEPAAPSEPTPRAAPPEPAARPAARSGGAAAALDVLRNAGMRVSSDRGRAGAAPAAKPAAQPAAEKPVA
PRPAAVQVPTPRAAARAPQAADSRQASPPWEDIPPDDYVPLSADEMFGGPPDDGFVPVFDSGPDDVRVTPRPAETRPSAP
VDTRPLPPAIALDPVGFDGEWPALAARLPLKGVAYQLAFNSELTAVDATTLKLSVPVPQYADAAQVAKLKAALADALGKP
VEVAVEVGPARRTAAALDAAARAARQREAEQEIHGDPFVQQLVRDFGARIVEGSVRPLADAAPDGPPPTLH
>Mature_790_residues
TYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACRE
IDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQK
IPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGML
GALDQTYMVRLLDALAAGGGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEWPEAGDLRRFADTLSP
EQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEPAVAAGSATGGQPSVPRAVPGPRVAAASVAAAKPASAAPAEA
VRQQAVAPAAPAVPAAPVVHTAPVQSGDETDRPAVKPAAVQAAAPAPVDAPVIETPQPQTAAAPQAEPAGDTPAPVRKEP
ESPAVVEQRSDEPAAPSEPTPRAAPPEPAARPAARSGGAAAALDVLRNAGMRVSSDRGRAGAAPAAKPAAQPAAEKPVAP
RPAAVQVPTPRAAARAPQAADSRQASPPWEDIPPDDYVPLSADEMFGGPPDDGFVPVFDSGPDDVRVTPRPAETRPSAPV
DTRPLPPAIALDPVGFDGEWPALAARLPLKGVAYQLAFNSELTAVDATTLKLSVPVPQYADAAQVAKLKAALADALGKPV
EVAVEVGPARRTAAALDAAARAARQREAEQEIHGDPFVQQLVRDFGARIVEGSVRPLADAAPDGPPPTLH

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=327, Percent_Identity=23.5474006116208, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI194306571, Length=325, Percent_Identity=23.0769230769231, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI194306567, Length=325, Percent_Identity=23.0769230769231, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1786676, Length=361, Percent_Identity=55.9556786703601, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1787341, Length=183, Percent_Identity=31.1475409836066, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787119, Length=303, Percent_Identity=28.0528052805281, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71986063, Length=245, Percent_Identity=26.530612244898, Blast_Score=69, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6324039, Length=245, Percent_Identity=26.1224489795918, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI18859927, Length=295, Percent_Identity=21.6949152542373, Blast_Score=74, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19921076, Length=304, Percent_Identity=23.6842105263158, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 82978; Mature: 82846

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAK
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHH
ALNCETGVTSQPCGVCRACREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARF
HHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCE
KVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQMPA
EEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCH
GHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM
HHHHHHHHHHHCCCCEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGALDQTYMVRLLDALAAGGGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPG
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SVLDEWPEAGDLRRFADTLSPEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEP
HHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHCHHHCCCCCHHHCHHHHHHHHHHHHCC
AVAAGSATGGQPSVPRAVPGPRVAAASVAAAKPASAAPAEAVRQQAVAPAAPAVPAAPVV
CHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCE
HTAPVQSGDETDRPAVKPAAVQAAAPAPVDAPVIETPQPQTAAAPQAEPAGDTPAPVRKE
EECCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PESPAVVEQRSDEPAAPSEPTPRAAPPEPAARPAARSGGAAAALDVLRNAGMRVSSDRGR
CCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCC
AGAAPAAKPAAQPAAEKPVAPRPAAVQVPTPRAAARAPQAADSRQASPPWEDIPPDDYVP
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
LSADEMFGGPPDDGFVPVFDSGPDDVRVTPRPAETRPSAPVDTRPLPPAIALDPVGFDGE
CCHHHHCCCCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCC
WPALAARLPLKGVAYQLAFNSELTAVDATTLKLSVPVPQYADAAQVAKLKAALADALGKP
CCHHHHHCCCCCEEEEEEECCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCC
VEVAVEVGPARRTAAALDAAARAARQREAEQEIHGDPFVQQLVRDFGARIVEGSVRPLAD
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHH
AAPDGPPPTLH
CCCCCCCCCCC
>Mature Secondary Structure 
TYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAK
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHH
ALNCETGVTSQPCGVCRACREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARF
HHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCE
KVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQMPA
EEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCH
GHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM
HHHHHHHHHHHCCCCEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGALDQTYMVRLLDALAAGGGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPG
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SVLDEWPEAGDLRRFADTLSPEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEP
HHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHCHHHCCCCCHHHCHHHHHHHHHHHHCC
AVAAGSATGGQPSVPRAVPGPRVAAASVAAAKPASAAPAEAVRQQAVAPAAPAVPAAPVV
CHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCE
HTAPVQSGDETDRPAVKPAAVQAAAPAPVDAPVIETPQPQTAAAPQAEPAGDTPAPVRKE
EECCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PESPAVVEQRSDEPAAPSEPTPRAAPPEPAARPAARSGGAAAALDVLRNAGMRVSSDRGR
CCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCC
AGAAPAAKPAAQPAAEKPVAPRPAAVQVPTPRAAARAPQAADSRQASPPWEDIPPDDYVP
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
LSADEMFGGPPDDGFVPVFDSGPDDVRVTPRPAETRPSAPVDTRPLPPAIALDPVGFDGE
CCHHHHCCCCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCC
WPALAARLPLKGVAYQLAFNSELTAVDATTLKLSVPVPQYADAAQVAKLKAALADALGKP
CCHHHHHCCCCCEEEEEEECCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCC
VEVAVEVGPARRTAAALDAAARAARQREAEQEIHGDPFVQQLVRDFGARIVEGSVRPLAD
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHH
AAPDGPPPTLH
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]