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The map label for this gene is ttuB [H]

Identifier: 78066497

GI number: 78066497

Start: 2061738

End: 2063018

Strand: Reverse

Name: ttuB [H]

Synonym: Bcep18194_A5028

Alternate gene names: 78066497

Gene position: 2063018-2061738 (Counterclockwise)

Preceding gene: 78066498

Following gene: 78066496

Centisome position: 55.85

GC content: 65.11

Gene sequence:

>1281_bases
ATGGCCAATACTCTCGCTGCCCGCCGCTGGTGGACGATCATGCCGATCGTCTTCATCACGTACAGCCTCGCCTACCTCGA
CCGCGCGAACTACGGGTTCGCGGCCGCGGCCGGCATCAACCAGGACCTCGGGATCAGCAAGGGCCTGTCGTCGCTGATCG
GCGCGCTGTTCTTCCTCGGCTACTTCTTCTTCCAGATTCCCGGCGCGATCTATGCGGAACGCCGCAGCGTGAAGAAGCTC
GTGTTCGTCAGCCTCATCCTGTGGGGCGCCTGCGCGGCGCTCACGGGCGTGGTCAGCAACATCCCGTCGCTGATGGCGAT
CCGCTTCGTGCTCGGCGTCGTCGAGGCGGCCGTGATGCCGGCGATGCTGATCTACATCAGCAACTGGTTCACGAAGAACG
AGCGCTCGCGCGCGAACACGTTCCTGATCCTCGGCAACCCGGTCACCGTTTTGTGGATGTCGATCGTGTCGGGCTATCTG
GTGCACGAATTCGGCTGGCGCCACATGTTCATCGCCGAAGGCGTGCCGGCCGTGCTCTGGGCCGTGTGCTGGTGGTTCCT
CGTGCAGGACAAGCCGGCCGATTCGCCGTGGCTCAATGCGCAGGAAAAGCGTGACCTCGACGCCGCGCTCGCGGCCGAGC
AGGCAACGATCAAGCCCGTGCGCAACTATGGCGAAGCGTTCCGCTCGCCGGCCGTGATCAAGCTGTGCGCACAGTATTTC
TGCTGGAGCATCGGCGTGTACGGCTTCGTGCTGTGGCTGCCGTCGATCGTCAAGAACGGCTCCGACCTCGGGATGGTCGC
GACCGGCTGGCTGTCCGCGCTGCCGTATCTCGCGGCGACGATCGCGATGATTGTCGCGTCGTGGGCGTCCGACAAGGTCG
GTTCGCGGCGCGGTTTCGTGTGGCCGTTCCTGCTGATCGGTGCGGCTGCGTTCGCCGCATCGTACGCACTCGGCTCGTCG
CACTTCTGGATCTCGTATGCGCTGCTGGTCGTGGCTGGCGCCGCGATGTACGCGCCGTACGGCCCGTTCTTCGCGATCGT
GTCGGAACTGCTGCCGAAGAACGTCGCCGGCGGTGCGATGGCACTGATCAACAGCATGGGCGCGCTCGGCTCGTTCGTCG
GCTCGTACTTCGTCGGCTACCTGAACGGTGCGACCGGCTCGCCCGTCGCGTCGTATGCATTCATGAGCGCCGCACTCGTC
GCCGCGGTGATCCTCACGCTGTCCGTCAAACCCCAGGCGCGCGATACGCATCCGCTCGCGACGCCGCTGCAAGGAAAATG
A

Upstream 100 bases:

>100_bases
GATCCAGGTAAGCGCTAAAGCACTAACCTGGATCGACCGCGAAGCATGGGACCAGAGTAAGCGCTAAAGCGCTAACTCTG
GTCGACACGGAGACATTCTG

Downstream 100 bases:

>100_bases
ATCCGATGAAGCCCCGTATCGTCGCGTACAAGCCGCTGCCCGATGACGTCCTCGCGTACCTGCGCGAGCATGCGGACGTC
GTGCAGGCCGACGGCACCGC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MANTLAARRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLGYFFFQIPGAIYAERRSVKKL
VFVSLILWGACAALTGVVSNIPSLMAIRFVLGVVEAAVMPAMLIYISNWFTKNERSRANTFLILGNPVTVLWMSIVSGYL
VHEFGWRHMFIAEGVPAVLWAVCWWFLVQDKPADSPWLNAQEKRDLDAALAAEQATIKPVRNYGEAFRSPAVIKLCAQYF
CWSIGVYGFVLWLPSIVKNGSDLGMVATGWLSALPYLAATIAMIVASWASDKVGSRRGFVWPFLLIGAAAFAASYALGSS
HFWISYALLVVAGAAMYAPYGPFFAIVSELLPKNVAGGAMALINSMGALGSFVGSYFVGYLNGATGSPVASYAFMSAALV
AAVILTLSVKPQARDTHPLATPLQGK

Sequences:

>Translated_426_residues
MANTLAARRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLGYFFFQIPGAIYAERRSVKKL
VFVSLILWGACAALTGVVSNIPSLMAIRFVLGVVEAAVMPAMLIYISNWFTKNERSRANTFLILGNPVTVLWMSIVSGYL
VHEFGWRHMFIAEGVPAVLWAVCWWFLVQDKPADSPWLNAQEKRDLDAALAAEQATIKPVRNYGEAFRSPAVIKLCAQYF
CWSIGVYGFVLWLPSIVKNGSDLGMVATGWLSALPYLAATIAMIVASWASDKVGSRRGFVWPFLLIGAAAFAASYALGSS
HFWISYALLVVAGAAMYAPYGPFFAIVSELLPKNVAGGAMALINSMGALGSFVGSYFVGYLNGATGSPVASYAFMSAALV
AAVILTLSVKPQARDTHPLATPLQGK
>Mature_425_residues
ANTLAARRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLGYFFFQIPGAIYAERRSVKKLV
FVSLILWGACAALTGVVSNIPSLMAIRFVLGVVEAAVMPAMLIYISNWFTKNERSRANTFLILGNPVTVLWMSIVSGYLV
HEFGWRHMFIAEGVPAVLWAVCWWFLVQDKPADSPWLNAQEKRDLDAALAAEQATIKPVRNYGEAFRSPAVIKLCAQYFC
WSIGVYGFVLWLPSIVKNGSDLGMVATGWLSALPYLAATIAMIVASWASDKVGSRRGFVWPFLLIGAAAFAASYALGSSH
FWISYALLVVAGAAMYAPYGPFFAIVSELLPKNVAGGAMALINSMGALGSFVGSYFVGYLNGATGSPVASYAFMSAALVA
AVILTLSVKPQARDTHPLATPLQGK

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9945322, Length=364, Percent_Identity=24.1758241758242, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI6912666, Length=245, Percent_Identity=24.0816326530612, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI9966811, Length=367, Percent_Identity=25.0681198910082, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI21322234, Length=259, Percent_Identity=25.8687258687259, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI154350196, Length=365, Percent_Identity=22.4657534246575, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI87082071, Length=372, Percent_Identity=28.2258064516129, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI87082320, Length=431, Percent_Identity=23.8979118329466, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI2367379, Length=292, Percent_Identity=24.6575342465753, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1789515, Length=420, Percent_Identity=23.5714285714286, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789152, Length=405, Percent_Identity=22.7160493827161, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17552542, Length=317, Percent_Identity=26.4984227129338, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI115533556, Length=363, Percent_Identity=25.8953168044077, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115533554, Length=363, Percent_Identity=25.8953168044077, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560030, Length=282, Percent_Identity=24.113475177305, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193205400, Length=353, Percent_Identity=23.2294617563739, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17535049, Length=431, Percent_Identity=24.8259860788863, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI86561091, Length=334, Percent_Identity=25.4491017964072, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25141318, Length=334, Percent_Identity=25.4491017964072, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25141316, Length=334, Percent_Identity=25.4491017964072, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI32565916, Length=193, Percent_Identity=24.3523316062176, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32565914, Length=193, Percent_Identity=24.3523316062176, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17566884, Length=183, Percent_Identity=25.1366120218579, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25141341, Length=276, Percent_Identity=25.7246376811594, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322612, Length=207, Percent_Identity=25.1207729468599, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321698, Length=327, Percent_Identity=21.7125382262997, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24580790, Length=349, Percent_Identity=25.5014326647564, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI45550460, Length=398, Percent_Identity=24.3718592964824, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24583789, Length=360, Percent_Identity=25, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24655255, Length=360, Percent_Identity=24.7222222222222, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24584153, Length=390, Percent_Identity=22.0512820512821, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24655271, Length=300, Percent_Identity=24.6666666666667, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI20130135, Length=300, Percent_Identity=24.6666666666667, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24654215, Length=262, Percent_Identity=23.6641221374046, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI19922400, Length=262, Percent_Identity=23.6641221374046, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24653727, Length=379, Percent_Identity=25.065963060686, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573299, Length=300, Percent_Identity=22, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24648416, Length=272, Percent_Identity=24.2647058823529, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356189, Length=272, Percent_Identity=24.2647058823529, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24641682, Length=282, Percent_Identity=23.4042553191489, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI62484226, Length=295, Percent_Identity=24.0677966101695, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24639764, Length=299, Percent_Identity=23.4113712374582, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24658674, Length=278, Percent_Identity=21.9424460431655, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573708, Length=264, Percent_Identity=23.1060606060606, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573707, Length=264, Percent_Identity=23.1060606060606, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20129235, Length=388, Percent_Identity=25, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46034; Mature: 45903

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTLAARRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLG
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHH
YFFFQIPGAIYAERRSVKKLVFVSLILWGACAALTGVVSNIPSLMAIRFVLGVVEAAVMP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLIYISNWFTKNERSRANTFLILGNPVTVLWMSIVSGYLVHEFGWRHMFIAEGVPAVLW
HHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEHHCCHHHHHH
AVCWWFLVQDKPADSPWLNAQEKRDLDAALAAEQATIKPVRNYGEAFRSPAVIKLCAQYF
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
CWSIGVYGFVLWLPSIVKNGSDLGMVATGWLSALPYLAATIAMIVASWASDKVGSRRGFV
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
WPFLLIGAAAFAASYALGSSHFWISYALLVVAGAAMYAPYGPFFAIVSELLPKNVAGGAM
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHH
ALINSMGALGSFVGSYFVGYLNGATGSPVASYAFMSAALVAAVILTLSVKPQARDTHPLA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
TPLQGK
CCCCCC
>Mature Secondary Structure 
ANTLAARRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHH
YFFFQIPGAIYAERRSVKKLVFVSLILWGACAALTGVVSNIPSLMAIRFVLGVVEAAVMP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLIYISNWFTKNERSRANTFLILGNPVTVLWMSIVSGYLVHEFGWRHMFIAEGVPAVLW
HHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEHHCCHHHHHH
AVCWWFLVQDKPADSPWLNAQEKRDLDAALAAEQATIKPVRNYGEAFRSPAVIKLCAQYF
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
CWSIGVYGFVLWLPSIVKNGSDLGMVATGWLSALPYLAATIAMIVASWASDKVGSRRGFV
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
WPFLLIGAAAFAASYALGSSHFWISYALLVVAGAAMYAPYGPFFAIVSELLPKNVAGGAM
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHH
ALINSMGALGSFVGSYFVGYLNGATGSPVASYAFMSAALVAAVILTLSVKPQARDTHPLA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
TPLQGK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]