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The map label for this gene is mogA

Identifier: 78065665

GI number: 78065665

Start: 1127198

End: 1127818

Strand: Reverse

Name: mogA

Synonym: Bcep18194_A4193

Alternate gene names: 78065665

Gene position: 1127818-1127198 (Counterclockwise)

Preceding gene: 78065666

Following gene: 78065663

Centisome position: 30.53

GC content: 69.4

Gene sequence:

>621_bases
ATGACGACGACGAAGCGTAACCACCCGGACGAGCTCGTCGTCGGCCTCGTGTCGATCAGCGACCGCGCGAGCACGGGTGT
CTACGAGGACAAAGGCATTCCCGCGCTGCAGGAATGGCTCGCCGGCGCGCTGGTGTCGCCGTGGCGCGCCGAAACGCGCC
TGATCCAGGACGATGCGCCCACGATCTCCGCCACGCTCGCCGAGCTCGTCGACGTCGCGGGATGCGACCTCGTGCTGACG
ACGGGCGGCACGGGCCCCGCGCGCCGCGACGTGACGCCCGAGGCCACGCTGGCCGTGGCGACGAAGGAAATGCCGGGATT
CGGCGAACAGATGCGGCAGATCAGCCTGAATTTCGTGCCGACCGCGATCCTGTCGCGGCAGGTCGCGGTGATCCGCGAGA
CGGCCGACCATGCGGCGCTGATCGTCAACCTGCCAGGCCAGCCGAAGTCGATCCGGGAAACGCTCGAAGGGCTGCGCGAT
GCCGACGGCAAGTCGACCGTGCCCGGCATCTTCGCCGCGGTGCCTTACTGCATCGACCTGATCGGCGGCCCCTACATCGA
GACCGACGCCGCGGTGGTCGCGGCGTTCCGGCCGAAAAGCGCTCAGCGCGCACCGCGCTAA

Upstream 100 bases:

>100_bases
AAGCCGCCGCGCTATTTCCGCGAGCTGTTCCAGTGGATCAAGACCGCCGGCGGCACGTCCAATGCGGACGACGAAGCGGC
GGACGACGCCGGAGACGACC

Downstream 100 bases:

>100_bases
GCGTGTGCCGGCCCGCTCAGGCGGCCGGCGCGGACTCGCCGGCCGAAGCAGACGCGGCCGGAATCAGGAAATGCTCGCGG
TAGTACTTCAGCTCGTCGAT

Product: molybdenum cofactor biosynthesis protein MogA

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MTTTKRNHPDELVVGLVSISDRASTGVYEDKGIPALQEWLAGALVSPWRAETRLIQDDAPTISATLAELVDVAGCDLVLT
TGGTGPARRDVTPEATLAVATKEMPGFGEQMRQISLNFVPTAILSRQVAVIRETADHAALIVNLPGQPKSIRETLEGLRD
ADGKSTVPGIFAAVPYCIDLIGGPYIETDAAVVAAFRPKSAQRAPR

Sequences:

>Translated_206_residues
MTTTKRNHPDELVVGLVSISDRASTGVYEDKGIPALQEWLAGALVSPWRAETRLIQDDAPTISATLAELVDVAGCDLVLT
TGGTGPARRDVTPEATLAVATKEMPGFGEQMRQISLNFVPTAILSRQVAVIRETADHAALIVNLPGQPKSIRETLEGLRD
ADGKSTVPGIFAAVPYCIDLIGGPYIETDAAVVAAFRPKSAQRAPR
>Mature_205_residues
TTTKRNHPDELVVGLVSISDRASTGVYEDKGIPALQEWLAGALVSPWRAETRLIQDDAPTISATLAELVDVAGCDLVLTT
GGTGPARRDVTPEATLAVATKEMPGFGEQMRQISLNFVPTAILSRQVAVIRETADHAALIVNLPGQPKSIRETLEGLRDA
DGKSTVPGIFAAVPYCIDLIGGPYIETDAAVVAAFRPKSAQRAPR

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=180, Percent_Identity=35, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI10880983, Length=180, Percent_Identity=35, Blast_Score=91, Evalue=9e-19,
Organism=Escherichia coli, GI1786190, Length=194, Percent_Identity=71.6494845360825, Blast_Score=279, Evalue=9e-77,
Organism=Caenorhabditis elegans, GI17564954, Length=148, Percent_Identity=37.1621621621622, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI17136978, Length=173, Percent_Identity=30.0578034682081, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24638841, Length=173, Percent_Identity=30.0578034682081, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 21855; Mature: 21724

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTKRNHPDELVVGLVSISDRASTGVYEDKGIPALQEWLAGALVSPWRAETRLIQDDAP
CCCCCCCCCHHHEEEHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHEEECCCCC
TISATLAELVDVAGCDLVLTTGGTGPARRDVTPEATLAVATKEMPGFGEQMRQISLNFVP
HHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHEEEECCCCCCHHHHHHHHHHHHHH
TAILSRQVAVIRETADHAALIVNLPGQPKSIRETLEGLRDADGKSTVPGIFAAVPYCIDL
HHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
IGGPYIETDAAVVAAFRPKSAQRAPR
HCCCCEECCHHEEEEECCCCCCCCCC
>Mature Secondary Structure 
TTTKRNHPDELVVGLVSISDRASTGVYEDKGIPALQEWLAGALVSPWRAETRLIQDDAP
CCCCCCCCHHHEEEHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHEEECCCCC
TISATLAELVDVAGCDLVLTTGGTGPARRDVTPEATLAVATKEMPGFGEQMRQISLNFVP
HHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHEEEECCCCCCHHHHHHHHHHHHHH
TAILSRQVAVIRETADHAALIVNLPGQPKSIRETLEGLRDADGKSTVPGIFAAVPYCIDL
HHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
IGGPYIETDAAVVAAFRPKSAQRAPR
HCCCCEECCHHEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]