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The map label for this gene is pgl [H]

Identifier: 78065541

GI number: 78065541

Start: 995488

End: 996168

Strand: Reverse

Name: pgl [H]

Synonym: Bcep18194_A4069

Alternate gene names: 78065541

Gene position: 996168-995488 (Counterclockwise)

Preceding gene: 78065542

Following gene: 78065540

Centisome position: 26.97

GC content: 70.34

Gene sequence:

>681_bases
GTGATCGAGATTCACGCTTTCGACACCCAGGAAGCGCAAAGCGAAGCGCTCGCGCGCGCCGTCGGCGATGCGCTGCGCGC
CGCGCTCGCCGGCCCCGCGCGCCCGACGCTCGCGGTGTCGGGCGGCACGAGCCCGCGCCCGTTCCTGCAAACGCTGTCGC
ACACGGCGCTCGACTGGGCCGGCGTCGACGTGACGCTGGTCGACGACCGCTGGGTGCCGGAGGACGATGCAGCCAGCAAC
GCGCACCTCGTGCGCGACACGCTGCTGCAGCATGCAGCCGCCCCTGCCCGCTTCCTGCCGCTCGTCGATACGCGCGCCGC
GCTCGACGCGCACGTCGCCGCGCTGAACGCGAACGCCGACTACCGCGTGCCGACCGTCGCCGTGCTCGGCATGGGCGAGG
ACGGCCATACCGCGTCGATCTTCGCCGATGCGCCCGAATGGGATCACGCGATCGCGACGCCCGAGCGTTTCGTCGCCGTC
CATCCCGGCGTCGCGCCGCATGCGCGCGTGAGCTTCTCGCTCGATGCGCTCAAGCGCATTGACCGGCTGTTCCTGCTGAT
CGCGGGCAACGCGAAGCGCGCGGTGCTCGACGCCGCAGCCGCATCGTTGCAGAAGAACGCGATTTCCCAACTGGCCAACG
ACAAGGGGACCCAGCTCGATGTCTACTGGTGCGCAAAGTAA

Upstream 100 bases:

>100_bases
GAAGAGAACTGATGCAAACCGTTGCCGCGCACGCCACCGTACGCGGCAACGTGCCCCGCGATTCGTACGATTTGAACAGA
CAAAGCAGTCCGGAGGAGAT

Downstream 100 bases:

>100_bases
GGCGGCCGTCGCAGGCCAGCATGCCGACGGCCCGCGCCTGCTCGCGGACGTCGGCGGCACCAACGCGCGCTTCGCGCTGG
AAACCGGCCCGGGCGACATC

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MIEIHAFDTQEAQSEALARAVGDALRAALAGPARPTLAVSGGTSPRPFLQTLSHTALDWAGVDVTLVDDRWVPEDDAASN
AHLVRDTLLQHAAAPARFLPLVDTRAALDAHVAALNANADYRVPTVAVLGMGEDGHTASIFADAPEWDHAIATPERFVAV
HPGVAPHARVSFSLDALKRIDRLFLLIAGNAKRAVLDAAAASLQKNAISQLANDKGTQLDVYWCAK

Sequences:

>Translated_226_residues
MIEIHAFDTQEAQSEALARAVGDALRAALAGPARPTLAVSGGTSPRPFLQTLSHTALDWAGVDVTLVDDRWVPEDDAASN
AHLVRDTLLQHAAAPARFLPLVDTRAALDAHVAALNANADYRVPTVAVLGMGEDGHTASIFADAPEWDHAIATPERFVAV
HPGVAPHARVSFSLDALKRIDRLFLLIAGNAKRAVLDAAAASLQKNAISQLANDKGTQLDVYWCAK
>Mature_226_residues
MIEIHAFDTQEAQSEALARAVGDALRAALAGPARPTLAVSGGTSPRPFLQTLSHTALDWAGVDVTLVDDRWVPEDDAASN
AHLVRDTLLQHAAAPARFLPLVDTRAALDAHVAALNANADYRVPTVAVLGMGEDGHTASIFADAPEWDHAIATPERFVAV
HPGVAPHARVSFSLDALKRIDRLFLLIAGNAKRAVLDAAAASLQKNAISQLANDKGTQLDVYWCAK

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=174, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 23957; Mature: 23957

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEIHAFDTQEAQSEALARAVGDALRAALAGPARPTLAVSGGTSPRPFLQTLSHTALDWA
CEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHEEC
GVDVTLVDDRWVPEDDAASNAHLVRDTLLQHAAAPARFLPLVDTRAALDAHVAALNANAD
CCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHEEEEECCCC
YRVPTVAVLGMGEDGHTASIFADAPEWDHAIATPERFVAVHPGVAPHARVSFSLDALKRI
CCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCEEEECHHHHHHH
DRLFLLIAGNAKRAVLDAAAASLQKNAISQLANDKGTQLDVYWCAK
HHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
>Mature Secondary Structure
MIEIHAFDTQEAQSEALARAVGDALRAALAGPARPTLAVSGGTSPRPFLQTLSHTALDWA
CEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHEEC
GVDVTLVDDRWVPEDDAASNAHLVRDTLLQHAAAPARFLPLVDTRAALDAHVAALNANAD
CCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHEEEEECCCC
YRVPTVAVLGMGEDGHTASIFADAPEWDHAIATPERFVAVHPGVAPHARVSFSLDALKRI
CCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCEEEECHHHHHHH
DRLFLLIAGNAKRAVLDAAAASLQKNAISQLANDKGTQLDVYWCAK
HHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]