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The map label for this gene is mmlH [H]

Identifier: 78065510

GI number: 78065510

Start: 963181

End: 964503

Strand: Direct

Name: mmlH [H]

Synonym: Bcep18194_A4038

Alternate gene names: 78065510

Gene position: 963181-964503 (Clockwise)

Preceding gene: 78065506

Following gene: 78065511

Centisome position: 26.07

GC content: 70.14

Gene sequence:

>1323_bases
ATGTTCAAGGCGATCGACGCGCCGGCGGCCGGCGCGAAGCCGCGGCGCACGCCGCTCACGCGCGAGCAGGTCAAGGGCTT
CTGGGCCGTGTACGCGGGCTGGGTGCTCGACGGCGTGGATTCGGTGATCTACGCGCTGGTGCTGATTCCCGCGTTGACCG
AGCTGCTGCCGGCGTCCGGCATCGCGGCGACGCCCGCGAATCTCGGGATGTACGGCTCGATCCTGTTCGCGCTGTTCCTG
ATCGGCTGGGGGCTGTCGTTCATCTGGGGGCCGCTCGCCGACCGCTTCGGCCGCGTTCGTACGCTCGCCGCGAGCATCCT
GATCTACTCGGTGTTCACCGGCGCGGCCGCATTCGTGCACGACGTGTGGGCACTGGCCGCGTGCCGGCTGATCGCCGGGA
TCGGTGTCGGCGGCGAATGGGCGCTGGCGGGCACCTACGTCGCCGAGAGCTGGCCGGAAGACCGTCGCAAGATGGGCGCC
GGCTACCTGCAGACGGGCTACTACTTCGGCTTCTTCATCGCGGCGTGCCTGAACTACACGATCGGTGCGACCTACGGCTG
GCGCGCGATGTTCCTGTGCGGGCTCGCGCCGGCGCTGCTCGCGGTGTTCACCGTGATGCGCGTGAAGGAGCCCGGCCAGT
GGCGCCGGCATGACGCACGCGACGGCGACGTGGCCGACGCACGACGCGCCCATCCGATGCGCGAGATCTTCGCGCCGGCC
TTCCTGCGCCGCACGGTGACGAGCGCGAGCCTCGTCGGCGTCGCGATCGTCGGGCTGTGGGCCGGCTCCGTCTACGAGGC
GAGTGCGGTCAGCACGCTGGCGGCGCGCGCGGGCATCGATCACATCGGCGCGATGCGGCTGGCATCGATCGGCGCGGCGA
TCCTGTCGTGCGCGACGATCGCCGGCTGCCTGGTTGCGCCCTGGCTGTCCGAACGGCTCGGCCGCCGCACTGCGCTCGGC
GTGTATTTCGCGGGCATGGCCGCATCGATCGTGTTTGCGTTCGGCTGGGCGTTCTACCAGCCGAACGGGCTCGCGGCGTT
CATGGTGTCGCTCGCGTTCCTCGGTTTCTTCGGCGGCAATTTCGCGATCTTCTCGCTGTGGCTGCCCGAGCAGTACCCGA
CGCGCGTGCGGGCCACCGCGTTCGCGTTCAACGCGTCGGTCGGCCGCTTCATCGGCGCGGGCGTGAACTTCCTGCTCGGC
GCCGCGATACACGGTTACGGATCGCTCGGCGTGCCGGTCGCATGGACCGCGGCCGTGTTCGGGCTCGGCATCCTGATCCT
GCCGTTCGCGGTCGAAACCCGCCACCAGACGCTGCCCGAATGA

Upstream 100 bases:

>100_bases
TCGATGGTGTTTCTATACTCGTCTCACAAAAGAGCCAGCCTCCCGGCCATCCCGGACCGGACGCGGCAAAAGCGCCGGCC
TCGCCGGCAAGGAGACGAAG

Downstream 100 bases:

>100_bases
GCGGCACGCCGCGATCGTTCGGCAACAAGCCACACCCAGTCATCAATATCAGGAGTCCGGAATGCAGGCATTACAAGGAA
TCAGGGTCGTCGATCTGAGC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MFKAIDAPAAGAKPRRTPLTREQVKGFWAVYAGWVLDGVDSVIYALVLIPALTELLPASGIAATPANLGMYGSILFALFL
IGWGLSFIWGPLADRFGRVRTLAASILIYSVFTGAAAFVHDVWALAACRLIAGIGVGGEWALAGTYVAESWPEDRRKMGA
GYLQTGYYFGFFIAACLNYTIGATYGWRAMFLCGLAPALLAVFTVMRVKEPGQWRRHDARDGDVADARRAHPMREIFAPA
FLRRTVTSASLVGVAIVGLWAGSVYEASAVSTLAARAGIDHIGAMRLASIGAAILSCATIAGCLVAPWLSERLGRRTALG
VYFAGMAASIVFAFGWAFYQPNGLAAFMVSLAFLGFFGGNFAIFSLWLPEQYPTRVRATAFAFNASVGRFIGAGVNFLLG
AAIHGYGSLGVPVAWTAAVFGLGILILPFAVETRHQTLPE

Sequences:

>Translated_440_residues
MFKAIDAPAAGAKPRRTPLTREQVKGFWAVYAGWVLDGVDSVIYALVLIPALTELLPASGIAATPANLGMYGSILFALFL
IGWGLSFIWGPLADRFGRVRTLAASILIYSVFTGAAAFVHDVWALAACRLIAGIGVGGEWALAGTYVAESWPEDRRKMGA
GYLQTGYYFGFFIAACLNYTIGATYGWRAMFLCGLAPALLAVFTVMRVKEPGQWRRHDARDGDVADARRAHPMREIFAPA
FLRRTVTSASLVGVAIVGLWAGSVYEASAVSTLAARAGIDHIGAMRLASIGAAILSCATIAGCLVAPWLSERLGRRTALG
VYFAGMAASIVFAFGWAFYQPNGLAAFMVSLAFLGFFGGNFAIFSLWLPEQYPTRVRATAFAFNASVGRFIGAGVNFLLG
AAIHGYGSLGVPVAWTAAVFGLGILILPFAVETRHQTLPE
>Mature_440_residues
MFKAIDAPAAGAKPRRTPLTREQVKGFWAVYAGWVLDGVDSVIYALVLIPALTELLPASGIAATPANLGMYGSILFALFL
IGWGLSFIWGPLADRFGRVRTLAASILIYSVFTGAAAFVHDVWALAACRLIAGIGVGGEWALAGTYVAESWPEDRRKMGA
GYLQTGYYFGFFIAACLNYTIGATYGWRAMFLCGLAPALLAVFTVMRVKEPGQWRRHDARDGDVADARRAHPMREIFAPA
FLRRTVTSASLVGVAIVGLWAGSVYEASAVSTLAARAGIDHIGAMRLASIGAAILSCATIAGCLVAPWLSERLGRRTALG
VYFAGMAASIVFAFGWAFYQPNGLAAFMVSLAFLGFFGGNFAIFSLWLPEQYPTRVRATAFAFNASVGRFIGAGVNFLLG
AAIHGYGSLGVPVAWTAAVFGLGILILPFAVETRHQTLPE

Specific function: Probable uptake of 4-methylmuconolactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI216548223, Length=134, Percent_Identity=31.3432835820896, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI87082404, Length=424, Percent_Identity=25, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI87082231, Length=211, Percent_Identity=31.7535545023697, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1786229, Length=421, Percent_Identity=24.2280285035629, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790550, Length=324, Percent_Identity=26.2345679012346, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46892; Mature: 46892

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9461415 [H]