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The map label for this gene is livH [H]

Identifier: 78065485

GI number: 78065485

Start: 938092

End: 939711

Strand: Reverse

Name: livH [H]

Synonym: Bcep18194_A4013

Alternate gene names: 78065485

Gene position: 939711-938092 (Counterclockwise)

Preceding gene: 78065486

Following gene: 78065484

Centisome position: 25.44

GC content: 69.57

Gene sequence:

>1620_bases
ATGCCTACACGCTTTCGCCGAGCCGCCGTCGCGATCGTCGCGTGCGCCGCCCTCGCGGGCGGGCTGCCACGCGCCGCGTT
CGCGCTGACGGCGACCGATACCGCCGCGCTCGCCGGCGACGACTTCGACGCAAAGACGACCGCGATCGAACGGCTCGCCG
CCGACTCCGACCCACGCGCCGTCGCGCTGCTCAATGCGCTGTCGACCGGCGACGCGCTCGCGACCGGTGACGGCCGCCTG
CTGATCCAGACCGGCGACACCGCGCACGATGCGCTCACGCAGGCCACGACGCCGGCCGGCGACGCGCAGCCCGTGATGCT
GAACAACCTGCTGCGCACGAAGATAACTGGTGCGCTGTCGGGGCTCGCGCTCGCGTCGCCCGACGTCGCCGCGCGTCGCG
ACGCGATCGATGCATTGCTGAAATCGCCCGACCCGGCGCTCAAGCCGATGATCGACCGCGCGCGTGCGAAGGAAACCGAT
CCCGCGCTGAAGCGCCGCCTCGACGCACTGTGGGCGATCGCCGCGCTGCACGATGCCGATCCGGCGAAGCGCCTCGAAGC
CGTGCAGGTGGTGGCTGCACGCCGCGACCTCGACATGATCGAACAGTTGCGCCCGCTCGTCGCGAAGAATGCCGACGGCA
GCTACGCGGAACCCGACGCGCGCGTGCGCGCCGCCGCGCAGCAAGGACTCGACGCATTGCACACGCTGCAGCGCCGCGGC
GAGATCGTCGGCACCTTGTTCGCGGGCCTGTCGCTCGGCAGTGTGCTGCTGCTCGCCGCGCTCGGCCTCGCGATCACGTA
CGGGCTGATCGGCGTGATCAACATGGCGCACGGCGAATTCCTGATGATCGGTGCGTACGCAACCTATGTCGTGCAGACGC
TGATCCAGCGCTACGCGCCCGGCGCGTTCGACTGGTATCCGCTCGTCGCGGTGCCGGTGTCGTTCGTGACGGCCGCGCTC
GTCGGCATCGTGCTCGAACGGCTCGTGCTGCGGCACCTGTATGGCCGCCCGCTCGAGACGTTGCTCGCGACGTTCGGCGT
GAGCCTGATCCTGATCCAGGCGACGCGCATGCTGTTCGGCGCGCAGAACGTGCAGGTCGTGAACCCGTCGTGGATGAGCG
GCGGCGTGACCGTGATGCAGAACCTGATCCTGCCGTACAACCGGCTCGCGATCCTCGCGTTCGCACTCGCGGTGGTATTC
GTCGCGTGGGCGGTGCTGACGAAGACGCGGCTCGGCCTGTTCGTGCGCGCCGTCACGCAGAACCGCCGGATGGCCGCCTG
CGTCGGCGTGAAGACCGCGCGCGTCGACGCGTATGCGTTCGCATTCGGCGCGGGCATCGCGGGCCTCGGCGGCTGTGCGC
TGTCGCAGATCGGCAACGTGGGCCCCGACCTTGGCCAGAACTACATCATCGATTCGTTCATGGCGGTCGTGCTCGGCGGT
GTCGGGCAGATCGCCGGCACCGTGCTCGGCGGCTTCGGGCTCGGCCTCGCGAGCAAGGCGATCGAGCCGTTCTGGGGCGC
CGTGCTCGCGAAGATCGCGGTGCTCGTGATGATCGTGCTGTTCATCCAGAAACGTCCGCAGGGCATGTTTGCCCCGAAGG
GCCGCAGTGCGGAGGCTTGA

Upstream 100 bases:

>100_bases
ATGCCGAACCCGATGTGCCGTCCGCGCTTGCCGAGATGAACCGCACGCGCCCGCGCATCGCCGCACGCATCCGCTTCCCC
ACGCCCGACAGGATTTCCCG

Downstream 100 bases:

>100_bases
CGTGACTTCATTCACCCACTCGTTGTCCAATCCGGCCGCCGATGCGCCGAAGCCGGCTGCCGCCGCACGCACGGAAGAGC
GCTTCGCGCTCGGCCTGCCG

Product: branched chain amino acid ABC transporter inner membrane protein

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MPTRFRRAAVAIVACAALAGGLPRAAFALTATDTAALAGDDFDAKTTAIERLAADSDPRAVALLNALSTGDALATGDGRL
LIQTGDTAHDALTQATTPAGDAQPVMLNNLLRTKITGALSGLALASPDVAARRDAIDALLKSPDPALKPMIDRARAKETD
PALKRRLDALWAIAALHDADPAKRLEAVQVVAARRDLDMIEQLRPLVAKNADGSYAEPDARVRAAAQQGLDALHTLQRRG
EIVGTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLIQRYAPGAFDWYPLVAVPVSFVTAAL
VGIVLERLVLRHLYGRPLETLLATFGVSLILIQATRMLFGAQNVQVVNPSWMSGGVTVMQNLILPYNRLAILAFALAVVF
VAWAVLTKTRLGLFVRAVTQNRRMAACVGVKTARVDAYAFAFGAGIAGLGGCALSQIGNVGPDLGQNYIIDSFMAVVLGG
VGQIAGTVLGGFGLGLASKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFAPKGRSAEA

Sequences:

>Translated_539_residues
MPTRFRRAAVAIVACAALAGGLPRAAFALTATDTAALAGDDFDAKTTAIERLAADSDPRAVALLNALSTGDALATGDGRL
LIQTGDTAHDALTQATTPAGDAQPVMLNNLLRTKITGALSGLALASPDVAARRDAIDALLKSPDPALKPMIDRARAKETD
PALKRRLDALWAIAALHDADPAKRLEAVQVVAARRDLDMIEQLRPLVAKNADGSYAEPDARVRAAAQQGLDALHTLQRRG
EIVGTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLIQRYAPGAFDWYPLVAVPVSFVTAAL
VGIVLERLVLRHLYGRPLETLLATFGVSLILIQATRMLFGAQNVQVVNPSWMSGGVTVMQNLILPYNRLAILAFALAVVF
VAWAVLTKTRLGLFVRAVTQNRRMAACVGVKTARVDAYAFAFGAGIAGLGGCALSQIGNVGPDLGQNYIIDSFMAVVLGG
VGQIAGTVLGGFGLGLASKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFAPKGRSAEA
>Mature_538_residues
PTRFRRAAVAIVACAALAGGLPRAAFALTATDTAALAGDDFDAKTTAIERLAADSDPRAVALLNALSTGDALATGDGRLL
IQTGDTAHDALTQATTPAGDAQPVMLNNLLRTKITGALSGLALASPDVAARRDAIDALLKSPDPALKPMIDRARAKETDP
ALKRRLDALWAIAALHDADPAKRLEAVQVVAARRDLDMIEQLRPLVAKNADGSYAEPDARVRAAAQQGLDALHTLQRRGE
IVGTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLIQRYAPGAFDWYPLVAVPVSFVTAALV
GIVLERLVLRHLYGRPLETLLATFGVSLILIQATRMLFGAQNVQVVNPSWMSGGVTVMQNLILPYNRLAILAFALAVVFV
AWAVLTKTRLGLFVRAVTQNRRMAACVGVKTARVDAYAFAFGAGIAGLGGCALSQIGNVGPDLGQNYIIDSFMAVVLGGV
GQIAGTVLGGFGLGLASKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFAPKGRSAEA

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=297, Percent_Identity=29.2929292929293, Blast_Score=93, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 56470; Mature: 56339

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTRFRRAAVAIVACAALAGGLPRAAFALTATDTAALAGDDFDAKTTAIERLAADSDPRA
CCCHHHHHHHHHHHHHHHHCCCCHHHEEEEECCHHHHCCCCCCHHHHHHHHHHCCCCCHH
VALLNALSTGDALATGDGRLLIQTGDTAHDALTQATTPAGDAQPVMLNNLLRTKITGALS
HHHHHHHCCCCEEEECCCEEEEEECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
GLALASPDVAARRDAIDALLKSPDPALKPMIDRARAKETDPALKRRLDALWAIAALHDAD
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
PAKRLEAVQVVAARRDLDMIEQLRPLVAKNADGSYAEPDARVRAAAQQGLDALHTLQRRG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EIVGTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLIQRYAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCC
GAFDWYPLVAVPVSFVTAALVGIVLERLVLRHLYGRPLETLLATFGVSLILIQATRMLFG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
AQNVQVVNPSWMSGGVTVMQNLILPYNRLAILAFALAVVFVAWAVLTKTRLGLFVRAVTQ
CCCCEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NRRMAACVGVKTARVDAYAFAFGAGIAGLGGCALSQIGNVGPDLGQNYIIDSFMAVVLGG
CCCCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
VGQIAGTVLGGFGLGLASKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFAPKGRSAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PTRFRRAAVAIVACAALAGGLPRAAFALTATDTAALAGDDFDAKTTAIERLAADSDPRA
CCHHHHHHHHHHHHHHHHCCCCHHHEEEEECCHHHHCCCCCCHHHHHHHHHHCCCCCHH
VALLNALSTGDALATGDGRLLIQTGDTAHDALTQATTPAGDAQPVMLNNLLRTKITGALS
HHHHHHHCCCCEEEECCCEEEEEECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
GLALASPDVAARRDAIDALLKSPDPALKPMIDRARAKETDPALKRRLDALWAIAALHDAD
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
PAKRLEAVQVVAARRDLDMIEQLRPLVAKNADGSYAEPDARVRAAAQQGLDALHTLQRRG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EIVGTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLIQRYAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCC
GAFDWYPLVAVPVSFVTAALVGIVLERLVLRHLYGRPLETLLATFGVSLILIQATRMLFG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
AQNVQVVNPSWMSGGVTVMQNLILPYNRLAILAFALAVVFVAWAVLTKTRLGLFVRAVTQ
CCCCEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NRRMAACVGVKTARVDAYAFAFGAGIAGLGGCALSQIGNVGPDLGQNYIIDSFMAVVLGG
CCCCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
VGQIAGTVLGGFGLGLASKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFAPKGRSAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]