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The map label for this gene is apaH

Identifier: 78065442

GI number: 78065442

Start: 889267

End: 890106

Strand: Reverse

Name: apaH

Synonym: Bcep18194_A3968

Alternate gene names: 78065442

Gene position: 890106-889267 (Counterclockwise)

Preceding gene: 78065447

Following gene: 78065433

Centisome position: 24.1

GC content: 70.48

Gene sequence:

>840_bases
ATGACCCGCACCCCCATCGCAATCGGCGACATCCAGGGCTGTCATTCCGCTCTCCAGTCGCTGCTCGACAAGCTGTCCCC
GCCCGCCGACACGCCGCTGTGGATCGCCGGCGACGTCGTCAACCGCGGCCCGGACTCCCTCGCCGCGCTGCGTGCGCTCG
TCGACCTCGGCCCGCGCGCGACCGTCGTGCTCGGCAATCACGACCTGCACCTGCTCGCGGTCTCCGCCGGCCTGCGCACC
GAGCGCCCGGGCGACACCATCGGCGAGATCCTCGATGCACCCGACGCCGATGCGCTGCTCGACTGGGTCCGCCACCGGCC
GTTTGTCCATGCGGAGAACGGGATGCTGCTGGTGCATGCGGGCGTGCTGCCGCAGTGGGATGCGACGCTCGTGCTGGAGC
TCGCCGACGAACTCCAGCGCGCGTTGCGCGCGCCCGACTGGCGCGACACGCTGCAGAAGCTGTACGGCAACGAGCCGAAT
CAATGGAGCCCGGATCTGAAGAAACGCGACCGGATGCGCGTCGCGTTCAACGCATTCACGCGTGTGCGCTTCTGCACGCC
CGACGGTGCGATGGAATTCAAGGCGAACGGCGGCCCCGACAGCGCGCCGCCCGGCTACCTGCCGTGGTTCGACGTACCGG
GGCGCCGCACGGAGGACGTGACGGTCGTGTTCGGCCACTGGGCCGCGCTCGGCCTGATGGTGCGCGAGAACGTGGTCGCG
CTCGATTCGGGATGTGTGTGGGGGAACCAGTTGTCGGCCGTGCGGCTGACGGCCGATCCGGCGCAGCGCACGGTCACGCA
GGTGCAGTGCGACGCGTGCCGCGCGCCGGGAGGAGAGTGA

Upstream 100 bases:

>100_bases
CAAATCAATACGTTAAAATTCCCCGAATACGCTCGCAGTTGCGTTGCAGCGATCGCATCCTTTTTCGACCCGCGTCAGGA
TTTGTAACAACCTACCTCTC

Downstream 100 bases:

>100_bases
TTAAGCGCTGATTCGCGGGGCCGGGAAGCGCGTCAACCCTCGCGCCCCGGCACGGGCGCATCGGCCGCCTCGCCGCCTGC
CGCTCCGGCGCCAACCTCGG

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MTRTPIAIGDIQGCHSALQSLLDKLSPPADTPLWIAGDVVNRGPDSLAALRALVDLGPRATVVLGNHDLHLLAVSAGLRT
ERPGDTIGEILDAPDADALLDWVRHRPFVHAENGMLLVHAGVLPQWDATLVLELADELQRALRAPDWRDTLQKLYGNEPN
QWSPDLKKRDRMRVAFNAFTRVRFCTPDGAMEFKANGGPDSAPPGYLPWFDVPGRRTEDVTVVFGHWAALGLMVRENVVA
LDSGCVWGNQLSAVRLTADPAQRTVTQVQCDACRAPGGE

Sequences:

>Translated_279_residues
MTRTPIAIGDIQGCHSALQSLLDKLSPPADTPLWIAGDVVNRGPDSLAALRALVDLGPRATVVLGNHDLHLLAVSAGLRT
ERPGDTIGEILDAPDADALLDWVRHRPFVHAENGMLLVHAGVLPQWDATLVLELADELQRALRAPDWRDTLQKLYGNEPN
QWSPDLKKRDRMRVAFNAFTRVRFCTPDGAMEFKANGGPDSAPPGYLPWFDVPGRRTEDVTVVFGHWAALGLMVRENVVA
LDSGCVWGNQLSAVRLTADPAQRTVTQVQCDACRAPGGE
>Mature_278_residues
TRTPIAIGDIQGCHSALQSLLDKLSPPADTPLWIAGDVVNRGPDSLAALRALVDLGPRATVVLGNHDLHLLAVSAGLRTE
RPGDTIGEILDAPDADALLDWVRHRPFVHAENGMLLVHAGVLPQWDATLVLELADELQRALRAPDWRDTLQKLYGNEPNQ
WSPDLKKRDRMRVAFNAFTRVRFCTPDGAMEFKANGGPDSAPPGYLPWFDVPGRRTEDVTVVFGHWAALGLMVRENVVAL
DSGCVWGNQLSAVRLTADPAQRTVTQVQCDACRAPGGE

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=253, Percent_Identity=43.8735177865613, Blast_Score=223, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 30382; Mature: 30251

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTPIAIGDIQGCHSALQSLLDKLSPPADTPLWIAGDVVNRGPDSLAALRALVDLGPRA
CCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCEEEECCHHCCCCHHHHHHHHHHHCCCCE
TVVLGNHDLHLLAVSAGLRTERPGDTIGEILDAPDADALLDWVRHRPFVHAENGMLLVHA
EEEECCCCEEEEEEECCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCEEECCCEEEEEE
GVLPQWDATLVLELADELQRALRAPDWRDTLQKLYGNEPNQWSPDLKKRDRMRVAFNAFT
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEHHE
RVRFCTPDGAMEFKANGGPDSAPPGYLPWFDVPGRRTEDVTVVFGHWAALGLMVRENVVA
EEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHCCEEE
LDSGCVWGNQLSAVRLTADPAQRTVTQVQCDACRAPGGE
EECCCEECCCCCEEEEECCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TRTPIAIGDIQGCHSALQSLLDKLSPPADTPLWIAGDVVNRGPDSLAALRALVDLGPRA
CCCCEEECCHHHHHHHHHHHHHHHCCCCCCCEEEECCHHCCCCHHHHHHHHHHHCCCCE
TVVLGNHDLHLLAVSAGLRTERPGDTIGEILDAPDADALLDWVRHRPFVHAENGMLLVHA
EEEECCCCEEEEEEECCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCEEECCCEEEEEE
GVLPQWDATLVLELADELQRALRAPDWRDTLQKLYGNEPNQWSPDLKKRDRMRVAFNAFT
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEHHE
RVRFCTPDGAMEFKANGGPDSAPPGYLPWFDVPGRRTEDVTVVFGHWAALGLMVRENVVA
EEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHCCEEE
LDSGCVWGNQLSAVRLTADPAQRTVTQVQCDACRAPGGE
EECCCEECCCCCEEEEECCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA