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The map label for this gene is groES

Identifier: 78065428

GI number: 78065428

Start: 877442

End: 877735

Strand: Direct

Name: groES

Synonym: Bcep18194_A3954

Alternate gene names: 78065428

Gene position: 877442-877735 (Clockwise)

Preceding gene: 78065421

Following gene: 78065429

Centisome position: 23.75

GC content: 63.27

Gene sequence:

>294_bases
ATGAACCTTCGTCCTTTGCACGATCGCGTGATCGTCAAGCGCCTGGATCAGGAAACCAAGACCGCCTCGGGCATCGTGAT
CCCCGACGCCGCTGCTGAAAAGCCGGACCAGGGCGAAGTCCTGGCCGTCGGCCCGGGCAAGCGCGACGACAAGGGCGCGC
CGATCGCGCTCGACGTGAAGGTCGGCGATCGCGTCCTGTTCGGCAAGTACGCAGGCCAGACCGTGAAGGTCGACGGCAAC
GAACTGCTGGTCATGCGCGAAGAAGACATCATGGCCGTGGTCAACGCGAAGTAA

Upstream 100 bases:

>100_bases
TTAGCACTCGCTGCACGAGAGTGCTAACAATTCTCTGCCGGGCGATAAGCCGGGCAGATTCCCTAAGCGTTCTTCAATCT
CAGTCAAGAGAGGAGTGAAT

Downstream 100 bases:

>100_bases
GCGTCCACCGACGGTACATATTCCCAAGAATTCAAGGAGTTAGAAGATGGCAGCTAAAGACGTCGTATTCGGCGATTCCG
CCCGTTCGAAGATGGTCGAA

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10 [H]

Number of amino acids: Translated: 97; Mature: 97

Protein sequence:

>97_residues
MNLRPLHDRVIVKRLDQETKTASGIVIPDAAAEKPDQGEVLAVGPGKRDDKGAPIALDVKVGDRVLFGKYAGQTVKVDGN
ELLVMREEDIMAVVNAK

Sequences:

>Translated_97_residues
MNLRPLHDRVIVKRLDQETKTASGIVIPDAAAEKPDQGEVLAVGPGKRDDKGAPIALDVKVGDRVLFGKYAGQTVKVDGN
ELLVMREEDIMAVVNAK
>Mature_97_residues
MNLRPLHDRVIVKRLDQETKTASGIVIPDAAAEKPDQGEVLAVGPGKRDDKGAPIALDVKVGDRVLFGKYAGQTVKVDGN
ELLVMREEDIMAVVNAK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Escherichia coli, GI1790585, Length=97, Percent_Identity=54.639175257732, Blast_Score=98, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17555568, Length=94, Percent_Identity=41.4893617021277, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324594, Length=92, Percent_Identity=42.3913043478261, Blast_Score=79, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356029, Length=91, Percent_Identity=45.0549450549451, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358317, Length=90, Percent_Identity=44.4444444444444, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 10462; Mature: 10462

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRPLHDRVIVKRLDQETKTASGIVIPDAAAEKPDQGEVLAVGPGKRDDKGAPIALDVK
CCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCEEEEEE
VGDRVLFGKYAGQTVKVDGNELLVMREEDIMAVVNAK
ECCEEEEECCCCCEEEECCCEEEEEECCCEEEEEECC
>Mature Secondary Structure
MNLRPLHDRVIVKRLDQETKTASGIVIPDAAAEKPDQGEVLAVGPGKRDDKGAPIALDVK
CCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCEEEEEE
VGDRVLFGKYAGQTVKVDGNELLVMREEDIMAVVNAK
ECCEEEEECCCCCEEEECCCEEEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA