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The map label for this gene is exbB [H]

Identifier: 78065214

GI number: 78065214

Start: 627904

End: 628572

Strand: Direct

Name: exbB [H]

Synonym: Bcep18194_A3738

Alternate gene names: 78065214

Gene position: 627904-628572 (Clockwise)

Preceding gene: 78065213

Following gene: 78065215

Centisome position: 17.0

GC content: 71.9

Gene sequence:

>669_bases
ATGGCGATACCCACCGGCGTTGTCCACTACCTCGAAAGCGGCGATGCGATCACGCATGCCGTCGCCTATGTGCTGCTGGC
GATGTCCATCGCCAGCTGGTGCTTCCTCTTCATGAAAGCCTGGCTCCTGGTCCGCGCGAAGCGGCAGGGGCCGCGCGCGC
TCGCCGCGTTCTGGCGCGCGCCGTCGCTCGACGCGGGCATTGCCGCGCTCGCCGGCGCCGATCGCGAGCGCGTGTTCGTG
CCGCTCGCCGAAGCCGCCCGCGATGCGGCCGACGATCACGACCCGGCCGCGCTGGCCGCGCGTGTCGACCGCAGCGAACG
CGTGCTGCGCGCGCTGCGGCACGCGATGCTGCGCTCGCAGCGGCGCCTCGAATTCGGCCAGGTGCTGCTCGCGTCGATCG
GCAGCACCGCGCCGTTCGTCGGGCTGCTGGGCACCGTGTGGGGCATCTACCACGCGCTCGGCAGCATCGCCGCGAGCGGG
CAGGCGCAGATCGAGAACGTCGCGGGGCCGGTCGGCGAGGCGCTGATCATGACCGCGTTCGGGCTCGTCGTCGCGATTCC
CGCGGTGCTGGCCTACAACATCCTCGGGCGGCTCGTGCGGCAGCTCGCCGAGGAGCTCGACGGCTTTGCGCGCGACCTGC
ACGTGTTCGTGTGCGCGCAGGAAGCCTGA

Upstream 100 bases:

>100_bases
AGGCGCGTTGCGCGCGGTCCACTTCCTGTCGGCGCGCGGCGCCGGCCTGTTCGACATGCAGGACGTGCTCGGCCTGCGCT
GACCCCACGGGGAAACTCCG

Downstream 100 bases:

>100_bases
CGCACCCATTCCGGAGAAGCGGCCATGGCATTCGGCGGACTCGAGCACCACAAGACGTCCGCGCCGATGGCGGAGATCAA
CATGACTCCGCTGATCGACG

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MAIPTGVVHYLESGDAITHAVAYVLLAMSIASWCFLFMKAWLLVRAKRQGPRALAAFWRAPSLDAGIAALAGADRERVFV
PLAEAARDAADDHDPAALAARVDRSERVLRALRHAMLRSQRRLEFGQVLLASIGSTAPFVGLLGTVWGIYHALGSIAASG
QAQIENVAGPVGEALIMTAFGLVVAIPAVLAYNILGRLVRQLAEELDGFARDLHVFVCAQEA

Sequences:

>Translated_222_residues
MAIPTGVVHYLESGDAITHAVAYVLLAMSIASWCFLFMKAWLLVRAKRQGPRALAAFWRAPSLDAGIAALAGADRERVFV
PLAEAARDAADDHDPAALAARVDRSERVLRALRHAMLRSQRRLEFGQVLLASIGSTAPFVGLLGTVWGIYHALGSIAASG
QAQIENVAGPVGEALIMTAFGLVVAIPAVLAYNILGRLVRQLAEELDGFARDLHVFVCAQEA
>Mature_221_residues
AIPTGVVHYLESGDAITHAVAYVLLAMSIASWCFLFMKAWLLVRAKRQGPRALAAFWRAPSLDAGIAALAGADRERVFVP
LAEAARDAADDHDPAALAARVDRSERVLRALRHAMLRSQRRLEFGQVLLASIGSTAPFVGLLGTVWGIYHALGSIAASGQ
AQIENVAGPVGEALIMTAFGLVVAIPAVLAYNILGRLVRQLAEELDGFARDLHVFVCAQEA

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=200, Percent_Identity=34.5, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1789381, Length=191, Percent_Identity=33.5078534031414, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 23707; Mature: 23576

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIPTGVVHYLESGDAITHAVAYVLLAMSIASWCFLFMKAWLLVRAKRQGPRALAAFWRA
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
PSLDAGIAALAGADRERVFVPLAEAARDAADDHDPAALAARVDRSERVLRALRHAMLRSQ
CCCCHHHHHHHCCCCCCEEEEHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHH
RRLEFGQVLLASIGSTAPFVGLLGTVWGIYHALGSIAASGQAQIENVAGPVGEALIMTAF
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHH
GLVVAIPAVLAYNILGRLVRQLAEELDGFARDLHVFVCAQEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure 
AIPTGVVHYLESGDAITHAVAYVLLAMSIASWCFLFMKAWLLVRAKRQGPRALAAFWRA
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
PSLDAGIAALAGADRERVFVPLAEAARDAADDHDPAALAARVDRSERVLRALRHAMLRSQ
CCCCHHHHHHHCCCCCCEEEEHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHH
RRLEFGQVLLASIGSTAPFVGLLGTVWGIYHALGSIAASGQAQIENVAGPVGEALIMTAF
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHH
GLVVAIPAVLAYNILGRLVRQLAEELDGFARDLHVFVCAQEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]