| Definition | Xanthomonas campestris pv. vesicatoria str. 85-10 chromosome, complete genome. |
|---|---|
| Accession | NC_007508 |
| Length | 5,178,466 |
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The map label for this gene is dfp [H]
Identifier: 78049583
GI number: 78049583
Start: 4624018
End: 4625292
Strand: Reverse
Name: dfp [H]
Synonym: XCV4027
Alternate gene names: 78049583
Gene position: 4625292-4624018 (Counterclockwise)
Preceding gene: 78049589
Following gene: 78049582
Centisome position: 89.32
GC content: 69.88
Gene sequence:
>1275_bases GTGATCGGCTCCACTCAGGCCCGCCCCCTGGACGGACAGCGTTTGCTGCTGTGCGTCGGCGGAGGCATCGCCGCTTACAA ATCGCTCGAACTGGTCCGTCGCCTGCGCGACGCCGGTGCGCAGGTGCAGGTCGCCATGACCGGCGGTGCGCAACAATTCG TCACCCCGCTGAGCTTCCAGGCATTGTCCGGGCAGCCCACCCGCACCACGCTGTGGGACAGCGCCGCCGAGCAGGCGATG GGCCACATCGAACTTGCGCGCTGGGCCGACCGGGTGATCGTTGCCCCGGCGACCGCCGACCTGCTGGCGCGTCTGGCGCA TGGTCTGGCCGACGATCTGGTCACCACGCTGTGCCTGGCCACGACCGCGCCGCTGACCGTGGCGCCGGCCATGAACCACC GCATGTGGCTGCATCCGGCCACCCAGGCCAACATCGCCACCCTGCGTGCGCGGGGGGTGGCGGTGGTGGGCCCTGACGAC GGCCCGCTGGCGGAGGGCGAATCCGGCCCCGGCCGGCTGGCCGAACCGGCCGCGATCCTTGCGGCGCTGGCCGGCGGCGC GGCGGTCGCCAGCGCAGCCCCGGAGGGCACCAAGAGCGTTGCCGCGCCCGTGTTCATCCCCAGCAGCACCCAGCTGGAAG GCCTGCGCATCGTGATCAGCGCCGGCCCCACCTTCGAGGACCTGGACCCGGTGCGCTACGTCGGCAACCGCAGCAGCGGC AAGATGGCCTACGCCCTGGCCGCCGCCGCTGCCAGGCAGGGTGCCGATGTGGTGCTGGTCAGCGGGCCGGTGCATCAGAC CACCCCGGAGGGCGTGCAGCGCATCGACGTGCGCTCGGCCGCGCAGATGCGCGACGCGGTGCTGGGTGCATTCCCGGCCG ACATCTACATCGGCGCTGCCGCCGTGGCCGACTACACCCCCAAGCGGGTGGTGTCGCAAAAGATCAAGAAGACCGGCGAA ACGTTGACCCTGGAGCTGGTACGCACCCCAGACATCCTGTCCGAGGTCGCCGCGCAGACCGGGGCGCTGAAACTGGTGGT CGGTTTTGCTGCCGAAACGCACGATGTGGAGCATTACGCCCGTGGCAAGCTGGCGGCCAAGCGGCTGGACCTGATCATCG CCAACCAGGTGGGGATCGAAGGCGGCGGATTCGAAAGCGACAACAACGCAGCCACGGCCTATTGGCAGGGCGGCGAGCGT GTGTTCCCCAGCAGCAGCAAGACCGAGTTGGCAGACCAACTGCTGGCCCTGATCGCGGAGAGATTGCAGGCATGA
Upstream 100 bases:
>100_bases GCATATGGCGAGATTGCCGGTGCTCATCGCCGACGCCCATCAGGCCAAGCGGAGGCATCGGCTAATCTAGTTGTCCTTGT AACCGTAGGACGACCCCGAC
Downstream 100 bases:
>100_bases GCCCCCCAACCCAGTCCTTGCAGGTGAAGTTGCTCGACCCGCGCTTCGGCGATCTGTGGCCGCTGCCGGCCTACGCCACC GAATCCAGCGCCGGCATGGA
Product: bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase
Products: NA
Alternate protein names: DNA/pantothenate metabolism flavoprotein; Phosphopantothenoylcysteine decarboxylase; PPCDC; CoaC; Phosphopantothenate--cysteine ligase; CoaB; PPC synthetase; PPCS; Phosphopantothenoylcysteine synthase [H]
Number of amino acids: Translated: 424; Mature: 424
Protein sequence:
>424_residues MIGSTQARPLDGQRLLLCVGGGIAAYKSLELVRRLRDAGAQVQVAMTGGAQQFVTPLSFQALSGQPTRTTLWDSAAEQAM GHIELARWADRVIVAPATADLLARLAHGLADDLVTTLCLATTAPLTVAPAMNHRMWLHPATQANIATLRARGVAVVGPDD GPLAEGESGPGRLAEPAAILAALAGGAAVASAAPEGTKSVAAPVFIPSSTQLEGLRIVISAGPTFEDLDPVRYVGNRSSG KMAYALAAAAARQGADVVLVSGPVHQTTPEGVQRIDVRSAAQMRDAVLGAFPADIYIGAAAVADYTPKRVVSQKIKKTGE TLTLELVRTPDILSEVAAQTGALKLVVGFAAETHDVEHYARGKLAAKRLDLIIANQVGIEGGGFESDNNAATAYWQGGER VFPSSSKTELADQLLALIAERLQA
Sequences:
>Translated_424_residues MIGSTQARPLDGQRLLLCVGGGIAAYKSLELVRRLRDAGAQVQVAMTGGAQQFVTPLSFQALSGQPTRTTLWDSAAEQAM GHIELARWADRVIVAPATADLLARLAHGLADDLVTTLCLATTAPLTVAPAMNHRMWLHPATQANIATLRARGVAVVGPDD GPLAEGESGPGRLAEPAAILAALAGGAAVASAAPEGTKSVAAPVFIPSSTQLEGLRIVISAGPTFEDLDPVRYVGNRSSG KMAYALAAAAARQGADVVLVSGPVHQTTPEGVQRIDVRSAAQMRDAVLGAFPADIYIGAAAVADYTPKRVVSQKIKKTGE TLTLELVRTPDILSEVAAQTGALKLVVGFAAETHDVEHYARGKLAAKRLDLIIANQVGIEGGGFESDNNAATAYWQGGER VFPSSSKTELADQLLALIAERLQA >Mature_424_residues MIGSTQARPLDGQRLLLCVGGGIAAYKSLELVRRLRDAGAQVQVAMTGGAQQFVTPLSFQALSGQPTRTTLWDSAAEQAM GHIELARWADRVIVAPATADLLARLAHGLADDLVTTLCLATTAPLTVAPAMNHRMWLHPATQANIATLRARGVAVVGPDD GPLAEGESGPGRLAEPAAILAALAGGAAVASAAPEGTKSVAAPVFIPSSTQLEGLRIVISAGPTFEDLDPVRYVGNRSSG KMAYALAAAAARQGADVVLVSGPVHQTTPEGVQRIDVRSAAQMRDAVLGAFPADIYIGAAAVADYTPKRVVSQKIKKTGE TLTLELVRTPDILSEVAAQTGALKLVVGFAAETHDVEHYARGKLAAKRLDLIIANQVGIEGGGFESDNNAATAYWQGGER VFPSSSKTELADQLLALIAERLQA
Specific function: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine [H]
COG id: COG0452
COG function: function code H; Phosphopantothenoylcysteine synthetase/decarboxylase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the PPC synthetase family [H]
Homologues:
Organism=Homo sapiens, GI71725351, Length=180, Percent_Identity=34.4444444444444, Blast_Score=86, Evalue=7e-17, Organism=Escherichia coli, GI87082301, Length=416, Percent_Identity=51.9230769230769, Blast_Score=367, Evalue=1e-103, Organism=Caenorhabditis elegans, GI17560194, Length=183, Percent_Identity=29.5081967213115, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24657262, Length=181, Percent_Identity=28.7292817679558, Blast_Score=78, Evalue=1e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005252 - InterPro: IPR007085 - InterPro: IPR003382 [H]
Pfam domain/function: PF04127 DFP; PF02441 Flavoprotein [H]
EC number: =4.1.1.36; =6.3.2.5 [H]
Molecular weight: Translated: 44035; Mature: 44035
Theoretical pI: Translated: 6.41; Mature: 6.41
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIGSTQARPLDGQRLLLCVGGGIAAYKSLELVRRLRDAGAQVQVAMTGGAQQFVTPLSFQ CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHCCCCHH ALSGQPTRTTLWDSAAEQAMGHIELARWADRVIVAPATADLLARLAHGLADDLVTTLCLA CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHH TTAPLTVAPAMNHRMWLHPATQANIATLRARGVAVVGPDDGPLAEGESGPGRLAEPAAIL HCCCEEEECCCCCEEEECCCCCCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCCHHHHH AALAGGAAVASAAPEGTKSVAAPVFIPSSTQLEGLRIVISAGPTFEDLDPVRYVGNRSSG HHHHCCHHHHCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHCCCCCC KMAYALAAAAARQGADVVLVSGPVHQTTPEGVQRIDVRSAAQMRDAVLGAFPADIYIGAA CHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHH AVADYTPKRVVSQKIKKTGETLTLELVRTPDILSEVAAQTGALKLVVGFAAETHDVEHYA HHHCCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHH RGKLAAKRLDLIIANQVGIEGGGFESDNNAATAYWQGGERVFPSSSKTELADQLLALIAE HHHHHHHHHHEEEECCCCCCCCCCCCCCCCEEEEECCCCEECCCCCHHHHHHHHHHHHHH RLQA HHCC >Mature Secondary Structure MIGSTQARPLDGQRLLLCVGGGIAAYKSLELVRRLRDAGAQVQVAMTGGAQQFVTPLSFQ CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHCCCCHH ALSGQPTRTTLWDSAAEQAMGHIELARWADRVIVAPATADLLARLAHGLADDLVTTLCLA CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHH TTAPLTVAPAMNHRMWLHPATQANIATLRARGVAVVGPDDGPLAEGESGPGRLAEPAAIL HCCCEEEECCCCCEEEECCCCCCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCCHHHHH AALAGGAAVASAAPEGTKSVAAPVFIPSSTQLEGLRIVISAGPTFEDLDPVRYVGNRSSG HHHHCCHHHHCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHCCCCCC KMAYALAAAAARQGADVVLVSGPVHQTTPEGVQRIDVRSAAQMRDAVLGAFPADIYIGAA CHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHH AVADYTPKRVVSQKIKKTGETLTLELVRTPDILSEVAAQTGALKLVVGFAAETHDVEHYA HHHCCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHH RGKLAAKRLDLIIANQVGIEGGGFESDNNAATAYWQGGERVFPSSSKTELADQLLALIAE HHHHHHHHHHEEEECCCCCCCCCCCCCCCCEEEEECCCCEECCCCCHHHHHHHHHHHHHH RLQA HHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 10952301 [H]