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The map label for this gene is rimO [H]

Identifier: 78048443

GI number: 78048443

Start: 3282591

End: 3283967

Strand: Reverse

Name: rimO [H]

Synonym: XCV2887

Alternate gene names: 78048443

Gene position: 3283967-3282591 (Counterclockwise)

Preceding gene: 78048448

Following gene: 78048441

Centisome position: 63.42

GC content: 63.4

Gene sequence:

>1377_bases
ATGTCCCAGCTGAACCCTAAAGTCGGCTTCGTCAGCCTTGGCTGCCCGAAGGCGCTCGTCGATTCCGAACGCATCCTCAC
CCAGCTGCGCGTGGAGGGGTACGACATCGTGCCCAGCTACGACGCTGCCGATGTGGTGGTGGTCAATACCTGCGGCTTCA
TCGATTCGGCAGTGACCGAATCGCTGGACGCGATCGGCGAAGCGATGAACGCCAACGGCAAGGTCATCGTCACCGGCTGC
CTGGGCAAGCGCCCGGAGCAGATTCGTGAGGCGTATCCGCAGGTGCTGGCAGTATCCGGCCCGCAGGACTACCAGAGCGT
CATGGAGGCAGTGCACGCCGCGTTGCCGCCGCGTCACGACCCGTTCGTGGACCTGGTGCCGGACTACGGCATCAAGCTGA
CCCCGCGCCATTACGCTTACTTGAAGATTTCCGAAGGCTGCAATCACCGGTGCAGCTTCTGCATCATTCCCTCGATGCGC
GGCGATCTGGTCTCGCGTCCGGTCGATGAGGTGCTGCGCGAAGCCGAGCGGTTGGTGCGCGGTGGCGTCAAGGAATTGCT
GGTGGTGTCGCAGGACACCTCGGCCTATGGCGTGGACCTGAAGTACGCCGAGCGTCCGTGGCGCGACCGCATGTACCAGA
CCCGCATGAAGGCGCTGTGCGAGGGGTTGTCGGAGCTGGGCGTGTGGACGCGCCTGCATTACGTGTACCCGTATCCGCAC
GTGGACGATGTGATTGGGCTGATGGCCGAAGGCAGGCTGCTGCCGTATCTGGACATCCCGTTCCAGCACGCCAGCCCGCG
CATCCTCAAGTTGATGAAGCGCCCGGGCGCGGTGGAAAAAACCCTGGAGCGCGTGCAGCGCTGGAAGGCGATGTGCCCGG
AGATCACCGTGCGCTCGACCTTCATCGTCGGTTTCCCCGGCGAAACCGATGCCGAATTCGAATCCTTGCTGGACTTCCTG
GATCAGGCGCAGCTGGACCGCGTCGGTGCGTTTGCGTATTCGCCGGTCGATGGCGCCAGCGCCAACGCATTGCCGGATCA
GGTGCCCGAAGAAGTGAAACACGAGCGCCTGGCGCGCTTCATGGCCAAGCAGGCGCAGATCTCTGCGTTGCGCCTGGAAT
CCAAGATCGGCAGCGTGCAGCAGTGCCTGGTGGATGTGATCGAAGACGACATCGCGGTGGCCCGCTCGCGTGCCGATGCG
CCGGAAATCGATGGGCTGGTGCATATCCAGAACGGCGGCGAGCTCGGCTTGAAGGTGGGCGATCTGGTCGATGTGGAAAT
CACCGACAGCGACGAGCACGATCTGTTTGGCGATGCATTGCCGTCTGGCCCCGCGGTGCAGCAGCCAGGGCGGACATTGA
ACCTGCAGATCGTTTAG

Upstream 100 bases:

>100_bases
ACCCCGCTTGCGCGGCATGCGGTTCAGAGCGTCGCCCCCGCGCCGCTATAATTGACCCGCTCAGGCCCCAGGCCGCTCCG
CTTCCCAGGCTCCTGCTTCC

Downstream 100 bases:

>100_bases
CCGCAGCAGGATGCCGGCTGGCCGATGGCGTCGGCGCTCCCGACTGTGCCGAACCGTCGGCGCACATGCCGCGGTGGGCA
CGCCAAGCCGTAGGAGCGTG

Product: ribosomal protein S12 methylthiotransferase

Products: NA

Alternate protein names: S12 MTTase; S12 methylthiotransferase; Ribosome maturation factor RimO [H]

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MSQLNPKVGFVSLGCPKALVDSERILTQLRVEGYDIVPSYDAADVVVVNTCGFIDSAVTESLDAIGEAMNANGKVIVTGC
LGKRPEQIREAYPQVLAVSGPQDYQSVMEAVHAALPPRHDPFVDLVPDYGIKLTPRHYAYLKISEGCNHRCSFCIIPSMR
GDLVSRPVDEVLREAERLVRGGVKELLVVSQDTSAYGVDLKYAERPWRDRMYQTRMKALCEGLSELGVWTRLHYVYPYPH
VDDVIGLMAEGRLLPYLDIPFQHASPRILKLMKRPGAVEKTLERVQRWKAMCPEITVRSTFIVGFPGETDAEFESLLDFL
DQAQLDRVGAFAYSPVDGASANALPDQVPEEVKHERLARFMAKQAQISALRLESKIGSVQQCLVDVIEDDIAVARSRADA
PEIDGLVHIQNGGELGLKVGDLVDVEITDSDEHDLFGDALPSGPAVQQPGRTLNLQIV

Sequences:

>Translated_458_residues
MSQLNPKVGFVSLGCPKALVDSERILTQLRVEGYDIVPSYDAADVVVVNTCGFIDSAVTESLDAIGEAMNANGKVIVTGC
LGKRPEQIREAYPQVLAVSGPQDYQSVMEAVHAALPPRHDPFVDLVPDYGIKLTPRHYAYLKISEGCNHRCSFCIIPSMR
GDLVSRPVDEVLREAERLVRGGVKELLVVSQDTSAYGVDLKYAERPWRDRMYQTRMKALCEGLSELGVWTRLHYVYPYPH
VDDVIGLMAEGRLLPYLDIPFQHASPRILKLMKRPGAVEKTLERVQRWKAMCPEITVRSTFIVGFPGETDAEFESLLDFL
DQAQLDRVGAFAYSPVDGASANALPDQVPEEVKHERLARFMAKQAQISALRLESKIGSVQQCLVDVIEDDIAVARSRADA
PEIDGLVHIQNGGELGLKVGDLVDVEITDSDEHDLFGDALPSGPAVQQPGRTLNLQIV
>Mature_457_residues
SQLNPKVGFVSLGCPKALVDSERILTQLRVEGYDIVPSYDAADVVVVNTCGFIDSAVTESLDAIGEAMNANGKVIVTGCL
GKRPEQIREAYPQVLAVSGPQDYQSVMEAVHAALPPRHDPFVDLVPDYGIKLTPRHYAYLKISEGCNHRCSFCIIPSMRG
DLVSRPVDEVLREAERLVRGGVKELLVVSQDTSAYGVDLKYAERPWRDRMYQTRMKALCEGLSELGVWTRLHYVYPYPHV
DDVIGLMAEGRLLPYLDIPFQHASPRILKLMKRPGAVEKTLERVQRWKAMCPEITVRSTFIVGFPGETDAEFESLLDFLD
QAQLDRVGAFAYSPVDGASANALPDQVPEEVKHERLARFMAKQAQISALRLESKIGSVQQCLVDVIEDDIAVARSRADAP
EIDGLVHIQNGGELGLKVGDLVDVEITDSDEHDLFGDALPSGPAVQQPGRTLNLQIV

Specific function: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 [H]

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=469, Percent_Identity=26.4392324093817, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI28872782, Length=478, Percent_Identity=25.5230125523013, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI28872784, Length=478, Percent_Identity=25.5230125523013, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1787057, Length=434, Percent_Identity=67.0506912442396, Blast_Score=616, Evalue=1e-178,
Organism=Escherichia coli, GI1786882, Length=455, Percent_Identity=27.9120879120879, Blast_Score=159, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17553146, Length=462, Percent_Identity=25.3246753246753, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71996771, Length=253, Percent_Identity=26.0869565217391, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356207, Length=483, Percent_Identity=25.4658385093168, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI19922432, Length=374, Percent_Identity=25.1336898395722, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR012340
- InterPro:   IPR007197
- InterPro:   IPR005840
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 50547; Mature: 50416

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLNPKVGFVSLGCPKALVDSERILTQLRVEGYDIVPSYDAADVVVVNTCGFIDSAVTE
CCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCEEECCCCCCCCEEEEECCCHHHHHHHH
SLDAIGEAMNANGKVIVTGCLGKRPEQIREAYPQVLAVSGPQDYQSVMEAVHAALPPRHD
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCC
PFVDLVPDYGIKLTPRHYAYLKISEGCNHRCSFCIIPSMRGDLVSRPVDEVLREAERLVR
CCEEECCCCCCEECCCEEEEEEECCCCCCCCCEEEECCCCCHHHCCCHHHHHHHHHHHHH
GGVKELLVVSQDTSAYGVDLKYAERPWRDRMYQTRMKALCEGLSELGVWTRLHYVYPYPH
CCHHHEEEEECCCCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCCCC
VDDVIGLMAEGRLLPYLDIPFQHASPRILKLMKRPGAVEKTLERVQRWKAMCPEITVRST
HHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEE
FIVGFPGETDAEFESLLDFLDQAQLDRVGAFAYSPVDGASANALPDQVPEEVKHERLARF
EEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
MAKQAQISALRLESKIGSVQQCLVDVIEDDIAVARSRADAPEIDGLVHIQNGGELGLKVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEC
DLVDVEITDSDEHDLFGDALPSGPAVQQPGRTLNLQIV
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure 
SQLNPKVGFVSLGCPKALVDSERILTQLRVEGYDIVPSYDAADVVVVNTCGFIDSAVTE
CCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCEEECCCCCCCCEEEEECCCHHHHHHHH
SLDAIGEAMNANGKVIVTGCLGKRPEQIREAYPQVLAVSGPQDYQSVMEAVHAALPPRHD
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCC
PFVDLVPDYGIKLTPRHYAYLKISEGCNHRCSFCIIPSMRGDLVSRPVDEVLREAERLVR
CCEEECCCCCCEECCCEEEEEEECCCCCCCCCEEEECCCCCHHHCCCHHHHHHHHHHHHH
GGVKELLVVSQDTSAYGVDLKYAERPWRDRMYQTRMKALCEGLSELGVWTRLHYVYPYPH
CCHHHEEEEECCCCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCCCC
VDDVIGLMAEGRLLPYLDIPFQHASPRILKLMKRPGAVEKTLERVQRWKAMCPEITVRST
HHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEE
FIVGFPGETDAEFESLLDFLDQAQLDRVGAFAYSPVDGASANALPDQVPEEVKHERLARF
EEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
MAKQAQISALRLESKIGSVQQCLVDVIEDDIAVARSRADAPEIDGLVHIQNGGELGLKVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEC
DLVDVEITDSDEHDLFGDALPSGPAVQQPGRTLNLQIV
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA