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The map label for this gene is nuoA [H]

Identifier: 78048409

GI number: 78048409

Start: 3246310

End: 3246711

Strand: Reverse

Name: nuoA [H]

Synonym: XCV2853

Alternate gene names: 78048409

Gene position: 3246711-3246310 (Counterclockwise)

Preceding gene: 78048410

Following gene: 78048408

Centisome position: 62.7

GC content: 58.71

Gene sequence:

>402_bases
ATGCCGGCACGCGGCGCGTGCGGGCAGAGGCAAGAGAGAATCGCTGTGCTGGCCGAATATTTGCCGAGTCTGCTGTTTCT
GATCGTCGCCACCGGTATCGGCATCGTGCTGATGTTGGTCGGTCGATTCCTCGGTCCGCGTAGCCCGGACCCGCGCAAGC
TCTCTCCTTACGAGTGCGGCTTCGAAGCCTTCGAAGACGCGCGCATGAAGTTCGATGTGCGCTACTACCTGATCGCGATC
CAGTTCATCGTGTTCGATCTGGAAATCATCTTCATCGTGCCGTGGACGCAGGTGTTCATGGAGATCGGCGCACGTTCGCT
GGTCACCATGGGGCTGTTCGTCGGCATGTTGTTCCTCGGCTTTATCTACGTGTGGAAGAAGGGAGCGCTGGAATGGGAGT
GA

Upstream 100 bases:

>100_bases
AGCGACTTAGGTCGTAGGGGTTCGAGTCCCCTCTTGGGCACCATTGTTTGGCTGCAGTTCCTGCGCATCGCTTGTCGCGC
GCGGGGTCTGCCTATACCCC

Downstream 100 bases:

>100_bases
TTCAGACCCTGGATAGTCTGATGACCAACCCGATGCCGGAAGGCCGGGTGGAAGACATCCTGCGCCCGGAAGGCGAAAAC
CCGTTGCTCGAAAAGGGCTA

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MPARGACGQRQERIAVLAEYLPSLLFLIVATGIGIVLMLVGRFLGPRSPDPRKLSPYECGFEAFEDARMKFDVRYYLIAI
QFIVFDLEIIFIVPWTQVFMEIGARSLVTMGLFVGMLFLGFIYVWKKGALEWE

Sequences:

>Translated_133_residues
MPARGACGQRQERIAVLAEYLPSLLFLIVATGIGIVLMLVGRFLGPRSPDPRKLSPYECGFEAFEDARMKFDVRYYLIAI
QFIVFDLEIIFIVPWTQVFMEIGARSLVTMGLFVGMLFLGFIYVWKKGALEWE
>Mature_132_residues
PARGACGQRQERIAVLAEYLPSLLFLIVATGIGIVLMLVGRFLGPRSPDPRKLSPYECGFEAFEDARMKFDVRYYLIAIQ
FIVFDLEIIFIVPWTQVFMEIGARSLVTMGLFVGMLFLGFIYVWKKGALEWE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=117, Percent_Identity=32.4786324786325, Blast_Score=80, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 15191; Mature: 15060

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARGACGQRQERIAVLAEYLPSLLFLIVATGIGIVLMLVGRFLGPRSPDPRKLSPYECG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCC
FEAFEDARMKFDVRYYLIAIQFIVFDLEIIFIVPWTQVFMEIGARSLVTMGLFVGMLFLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
FIYVWKKGALEWE
HHHHHHCCCCCCC
>Mature Secondary Structure 
PARGACGQRQERIAVLAEYLPSLLFLIVATGIGIVLMLVGRFLGPRSPDPRKLSPYECG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCC
FEAFEDARMKFDVRYYLIAIQFIVFDLEIIFIVPWTQVFMEIGARSLVTMGLFVGMLFLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
FIYVWKKGALEWE
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA