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The map label for this gene is infC [H]

Identifier: 78048350

GI number: 78048350

Start: 3173989

End: 3174468

Strand: Reverse

Name: infC [H]

Synonym: XCV2794

Alternate gene names: 78048350

Gene position: 3174468-3173989 (Counterclockwise)

Preceding gene: 78048351

Following gene: 78048349

Centisome position: 61.3

GC content: 60.83

Gene sequence:

>480_bases
GTGCCGCGCGTTCGCGTGATCGGCAGTGACGGAGAGATGGTCGGCGTGTTGTCGCGCGACGAAGCGCTCGCCAAGGCCGA
AGAAGAAGGCCTGGATCTGGTCGAAATCCAGCCGCAGGCCGATCCGCCGGTCTGCAAGATCATGGATTTCGGCAAGTTCA
AGTTCGAGCAGCAGAAAAAGGCCAACGAGGCCAAGAAGAAGACCAAGCAGGTCGAGATCAAGGAACTCAAGTTCCGCCCG
GTCACCGACGAGGGCGACTACCAGATCAAGCTGCGCAACATGCGCCGTTTCCTGGAAGAGGGCGACAAGGTCAAGGTCAA
CATCCGCTTCCGTGGCCGTGAAATGAGCCATCAGGAGCTGGGCCGCGAGATGGCGGCGCGGATCGAGGCCGATCTGGGCG
ACGACATCGTCATCGAGTCGCGTCCGCGCCTGGAAGGGCGCCAGATGGTCATGATGATCGCTCCCAAGAAGAAGGTCTGA

Upstream 100 bases:

>100_bases
CCGGTCTGGATGATCCGGATGCGCCGGTTCGATTCCTCTGGGAGATTGCAATATCAGTACCACTGACAACAAACAGAACC
GCAAGAACCAAGAAATCCGT

Downstream 100 bases:

>100_bases
GGATCCGATTCGGCACTGCAACGGGCCCGACAGGTTTGTTGCAGTGCAAGCTCCACGATTTGCAACAATTCCCGGCAACG
GGTAGACTGCGCGGCCCGGT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MPRVRVIGSDGEMVGVLSRDEALAKAEEEGLDLVEIQPQADPPVCKIMDFGKFKFEQQKKANEAKKKTKQVEIKELKFRP
VTDEGDYQIKLRNMRRFLEEGDKVKVNIRFRGREMSHQELGREMAARIEADLGDDIVIESRPRLEGRQMVMMIAPKKKV

Sequences:

>Translated_159_residues
MPRVRVIGSDGEMVGVLSRDEALAKAEEEGLDLVEIQPQADPPVCKIMDFGKFKFEQQKKANEAKKKTKQVEIKELKFRP
VTDEGDYQIKLRNMRRFLEEGDKVKVNIRFRGREMSHQELGREMAARIEADLGDDIVIESRPRLEGRQMVMMIAPKKKV
>Mature_158_residues
PRVRVIGSDGEMVGVLSRDEALAKAEEEGLDLVEIQPQADPPVCKIMDFGKFKFEQQKKANEAKKKTKQVEIKELKFRPV
TDEGDYQIKLRNMRRFLEEGDKVKVNIRFRGREMSHQELGREMAARIEADLGDDIVIESRPRLEGRQMVMMIAPKKKV

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=156, Percent_Identity=59.6153846153846, Blast_Score=181, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 18343; Mature: 18211

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRVRVIGSDGEMVGVLSRDEALAKAEEEGLDLVEIQPQADPPVCKIMDFGKFKFEQQKK
CCCEEEECCCCCEEEEECCCHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCCCHHHHHH
ANEAKKKTKQVEIKELKFRPVTDEGDYQIKLRNMRRFLEEGDKVKVNIRFRGREMSHQEL
HHHHHHHHHCCEEEHEEEEECCCCCCEEEEHHHHHHHHHCCCEEEEEEEECCCCCCHHHH
GREMAARIEADLGDDIVIESRPRLEGRQMVMMIAPKKKV
HHHHHHHHHCCCCCCEEECCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
PRVRVIGSDGEMVGVLSRDEALAKAEEEGLDLVEIQPQADPPVCKIMDFGKFKFEQQKK
CCEEEECCCCCEEEEECCCHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCCCHHHHHH
ANEAKKKTKQVEIKELKFRPVTDEGDYQIKLRNMRRFLEEGDKVKVNIRFRGREMSHQEL
HHHHHHHHHCCEEEHEEEEECCCCCCEEEEHHHHHHHHHCCCEEEEEEEECCCCCCHHHH
GREMAARIEADLGDDIVIESRPRLEGRQMVMMIAPKKKV
HHHHHHHHHCCCCCCEEECCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]