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The map label for this gene is asnC [H]

Identifier: 78047215

GI number: 78047215

Start: 1867132

End: 1868526

Strand: Reverse

Name: asnC [H]

Synonym: XCV1659

Alternate gene names: 78047215

Gene position: 1868526-1867132 (Counterclockwise)

Preceding gene: 78047223

Following gene: 78047214

Centisome position: 36.08

GC content: 62.72

Gene sequence:

>1395_bases
ATGACGGTGGTCAGCGTTGAACATGCGCTTGCGGGAAAGCTCCCGGAAGGCGGCGAAGTCACGGTACGGGGGTGGGTGCG
CACCTTGCGCGGATCTGCCGGACTGGCCTTCATCAACGTGACCGACGGCTCGTGCTTCGCTCCGATCCAGGTGGTGGCCA
ACGACACGCTGCCCAATTTCGACGAGATCAAGCGGCTGACCAGCGGCTGCTCGCTGATCGCCAAGGGCGTACTCGTCAAG
TCGCAGGGCAAGGGCCAGTCGTTCGAGATCCAGGCCAGCGGCGTGGAGATCGTCGGTTGGGTCGAAGACCCGTTGACGTA
CCCAATCCAGCCCAAGCCGATGACGCCGGAATTCCTGCGTGAAGTGGCGCATCTGCGCCCGCGCACCAACCTGTTCGGTG
CGGTGACCCGCATCCGCAACTGCTTGGCGCAGGCGGTGCACCGCTTCTTCCATCAGAACGGATTCAACTGGATCAGCACG
CCGATCATCACCACCTCCGATGCCGAAGGTGCCGGGCAGATGTTCCGCGTCTCCACGCTGGACATGGTCAACCTGCCACG
CGATGCCAGCGGCAATGTGGATTTCAGCCGTGATTTCTTCGGCAAGGAAACCTTTCTGACCGTGTCCGGCCAGCTCAACG
TGGAGGCTTACTGCCTGGCGCTGAGCAAGGTCTACACCTTCGGCCCGACCTTCCGTGCCGAGAACAGCCACACCACGCGC
CATCTGGCCGAGTTCTGGATGATCGAGCCGGAAATCGCCTTTGCCGATCTTGCCGAAGACGCACGCCTGGCTGAGCAGTT
CCTCAAATACCTGTTCCGCGCGGTGCTCGATGAGCGTGGCGACGACCTGGCGTTCCTGGCCGAGCGCGTGGACAAGAACG
CAATCACCAAGCTCGAAGCGTTCATCAATGCACCGTTCGAGCAGATCGACTACACAGAGGCGGTAAAGCTGCTGCAGAAC
TCCGGCAAGAAGTTCGATTTCCCGGTGGAATGGGGCCTGGACCTGCAGACCGAGCACGAGCGCTGGCTCACCGAAGAACA
CATCGGCCGCCCGGTGGTGGTGACCAATTACCCCGAGCACATCAAGGCGTTCTACATGCGCTTGAACGATGACGGCAAGA
CCGTTGCGGCGATGGACGTGCTGGCGCCGGGCATCGGCGAAATCATCGGCGGCAGCCAGCGTGAAGAACGCCTGGACGTG
CTGGACGCGCGCATGGCGCAGTTCGGCCTGGATAAGGAGCACTACAGCTGGTATCGCGATTTCCGTCGCTACGGCTCGGT
GCCGCATGCCGGCTTCGGCCTGGGCTTCGAGCGGCTGGTGGTGTACGTGTGCGGGTTGAGCAACATCCGCGACGCGATCC
CCTACCCGCGTGCGCCAGGCAGCGCGGAGTTCTGA

Upstream 100 bases:

>100_bases
ACAAGCGCCGCCGTCGGCACGCGGTTCAGATGCTCGCGCCGGCGCGGCCGCAGCCAGTAAACTCGCAGGCCATTCAAGGT
CGCTACGGCGAGGAACAGTC

Downstream 100 bases:

>100_bases
GGTGAGCTTGCCGGCCGCCGTCCCCCTGCTGCAATCGCTGGCCTTCTGGCTAGCGGCGATCATGGCCGGGCTGACGGCGG
TACGGAGCGTGTTGCTGGCG

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MTVVSVEHALAGKLPEGGEVTVRGWVRTLRGSAGLAFINVTDGSCFAPIQVVANDTLPNFDEIKRLTSGCSLIAKGVLVK
SQGKGQSFEIQASGVEIVGWVEDPLTYPIQPKPMTPEFLREVAHLRPRTNLFGAVTRIRNCLAQAVHRFFHQNGFNWIST
PIITTSDAEGAGQMFRVSTLDMVNLPRDASGNVDFSRDFFGKETFLTVSGQLNVEAYCLALSKVYTFGPTFRAENSHTTR
HLAEFWMIEPEIAFADLAEDARLAEQFLKYLFRAVLDERGDDLAFLAERVDKNAITKLEAFINAPFEQIDYTEAVKLLQN
SGKKFDFPVEWGLDLQTEHERWLTEEHIGRPVVVTNYPEHIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDV
LDARMAQFGLDKEHYSWYRDFRRYGSVPHAGFGLGFERLVVYVCGLSNIRDAIPYPRAPGSAEF

Sequences:

>Translated_464_residues
MTVVSVEHALAGKLPEGGEVTVRGWVRTLRGSAGLAFINVTDGSCFAPIQVVANDTLPNFDEIKRLTSGCSLIAKGVLVK
SQGKGQSFEIQASGVEIVGWVEDPLTYPIQPKPMTPEFLREVAHLRPRTNLFGAVTRIRNCLAQAVHRFFHQNGFNWIST
PIITTSDAEGAGQMFRVSTLDMVNLPRDASGNVDFSRDFFGKETFLTVSGQLNVEAYCLALSKVYTFGPTFRAENSHTTR
HLAEFWMIEPEIAFADLAEDARLAEQFLKYLFRAVLDERGDDLAFLAERVDKNAITKLEAFINAPFEQIDYTEAVKLLQN
SGKKFDFPVEWGLDLQTEHERWLTEEHIGRPVVVTNYPEHIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDV
LDARMAQFGLDKEHYSWYRDFRRYGSVPHAGFGLGFERLVVYVCGLSNIRDAIPYPRAPGSAEF
>Mature_463_residues
TVVSVEHALAGKLPEGGEVTVRGWVRTLRGSAGLAFINVTDGSCFAPIQVVANDTLPNFDEIKRLTSGCSLIAKGVLVKS
QGKGQSFEIQASGVEIVGWVEDPLTYPIQPKPMTPEFLREVAHLRPRTNLFGAVTRIRNCLAQAVHRFFHQNGFNWISTP
IITTSDAEGAGQMFRVSTLDMVNLPRDASGNVDFSRDFFGKETFLTVSGQLNVEAYCLALSKVYTFGPTFRAENSHTTRH
LAEFWMIEPEIAFADLAEDARLAEQFLKYLFRAVLDERGDDLAFLAERVDKNAITKLEAFINAPFEQIDYTEAVKLLQNS
GKKFDFPVEWGLDLQTEHERWLTEEHIGRPVVVTNYPEHIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVL
DARMAQFGLDKEHYSWYRDFRRYGSVPHAGFGLGFERLVVYVCGLSNIRDAIPYPRAPGSAEF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=463, Percent_Identity=42.3326133909287, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI4758762, Length=455, Percent_Identity=27.6923076923077, Blast_Score=165, Evalue=9e-41,
Organism=Homo sapiens, GI45439306, Length=350, Percent_Identity=29.1428571428571, Blast_Score=122, Evalue=6e-28,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=67.381974248927, Blast_Score=668, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17556372, Length=425, Percent_Identity=32.4705882352941, Blast_Score=208, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI71984122, Length=461, Percent_Identity=30.58568329718, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17551876, Length=341, Percent_Identity=28.7390029325513, Blast_Score=109, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319872, Length=474, Percent_Identity=36.9198312236287, Blast_Score=292, Evalue=7e-80,
Organism=Saccharomyces cerevisiae, GI6321807, Length=461, Percent_Identity=31.236442516269, Blast_Score=208, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6323011, Length=348, Percent_Identity=28.735632183908, Blast_Score=110, Evalue=4e-25,
Organism=Drosophila melanogaster, GI19922416, Length=452, Percent_Identity=35.6194690265487, Blast_Score=276, Evalue=3e-74,
Organism=Drosophila melanogaster, GI19921528, Length=452, Percent_Identity=29.646017699115, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI17136276, Length=487, Percent_Identity=26.8993839835729, Blast_Score=113, Evalue=3e-25,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 51927; Mature: 51795

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVVSVEHALAGKLPEGGEVTVRGWVRTLRGSAGLAFINVTDGSCFAPIQVVANDTLPNF
CEEEEECHHHHCCCCCCCCEEHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCCCH
DEIKRLTSGCSLIAKGVLVKSQGKGQSFEIQASGVEIVGWVEDPLTYPIQPKPMTPEFLR
HHHHHHHHHHHHHHHCCEEECCCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCCHHHHH
EVAHLRPRTNLFGAVTRIRNCLAQAVHRFFHQNGFNWISTPIITTSDAEGAGQMFRVSTL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEECCCCCCCCEEEEEEE
DMVNLPRDASGNVDFSRDFFGKETFLTVSGQLNVEAYCLALSKVYTFGPTFRAENSHTTR
HHCCCCCCCCCCCCCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEECCCCCHHH
HLAEFWMIEPEIAFADLAEDARLAEQFLKYLFRAVLDERGDDLAFLAERVDKNAITKLEA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHH
FINAPFEQIDYTEAVKLLQNSGKKFDFPVEWGLDLQTEHERWLTEEHIGRPVVVTNYPEH
HHCCCHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCHHH
IKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARMAQFGLDKEHYSWYRD
HHHHHHEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
FRRYGSVPHAGFGLGFERLVVYVCGLSNIRDAIPYPRAPGSAEF
HHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TVVSVEHALAGKLPEGGEVTVRGWVRTLRGSAGLAFINVTDGSCFAPIQVVANDTLPNF
EEEEECHHHHCCCCCCCCEEHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCCCH
DEIKRLTSGCSLIAKGVLVKSQGKGQSFEIQASGVEIVGWVEDPLTYPIQPKPMTPEFLR
HHHHHHHHHHHHHHHCCEEECCCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCCHHHHH
EVAHLRPRTNLFGAVTRIRNCLAQAVHRFFHQNGFNWISTPIITTSDAEGAGQMFRVSTL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEECCCCCCCCEEEEEEE
DMVNLPRDASGNVDFSRDFFGKETFLTVSGQLNVEAYCLALSKVYTFGPTFRAENSHTTR
HHCCCCCCCCCCCCCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEECCCCCHHH
HLAEFWMIEPEIAFADLAEDARLAEQFLKYLFRAVLDERGDDLAFLAERVDKNAITKLEA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHH
FINAPFEQIDYTEAVKLLQNSGKKFDFPVEWGLDLQTEHERWLTEEHIGRPVVVTNYPEH
HHCCCHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCHHH
IKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARMAQFGLDKEHYSWYRD
HHHHHHEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
FRRYGSVPHAGFGLGFERLVVYVCGLSNIRDAIPYPRAPGSAEF
HHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]