Click here to switch to the map view.

The map label for this gene is ubiE [C]

Identifier: 78047160

GI number: 78047160

Start: 1811968

End: 1812963

Strand: Reverse

Name: ubiE [C]

Synonym: XCV1604

Alternate gene names: 78047160

Gene position: 1812963-1811968 (Counterclockwise)

Preceding gene: 78047167

Following gene: 78047159

Centisome position: 35.01

GC content: 67.37

Gene sequence:

>996_bases
ATGGATCTGGAAGACTGGTCGGCCCGCTTGAAGGTATTCGCCGACGCCACCCGAGTCCGCCTGCTGGCCTTGCTGGAGCA
GGAAGAACTCACCGTGGCCGAGCTGTCGGCCATCACCCGGCTGGCGCAGCCGCGGGTGTCCACGCACCTGGCCAAACTCA
AGGAAGCCGGGCTGGTCCGCGACCGCCGCGCCGGGGTATCGGCGTATTACCGCTTCGACGAAGTGTCGCTGGACCCGGCG
CAGCGCGCGCTGTGGCTGGCACTGAGCACCGGCAGCGACGATCCGTTGTTGCGCCAGGATGCCGAGCGCGTGGCCGCGGT
GTTGGCCAACCGTGCCGCGGACCAGAACTGGGCCGATTCGGTGGCCGGCGACATGGAGCGGCATTACTCGCCGGGACGCA
CCTGGGAGGCCCTGGCGCGCACCGCCTTGCCCCTGCTGGAAACCGGCGACGTGCTCGATATCGCGTCCGGCGACGGCGTG
CTGGCCGAACTGGTGGCACCGCATGCCACCCGCTATATCTGCATCGATACCAGCGCGCGCGTGGTTGCGGCCGCCAGCGA
GCGCCTGCGCAAACTACGCAACGTGGAAGTGCGCGAAGGCGATATGCATGCGCTGCCATTCCCCGATGCCAGCTTCGACC
TGGTGGTGCTGATGCACGCACTGACCTACGCGGCCAAACCGGCGCAGGCGGTGGCCGAGTCGGCGCGCGTGCTGCGCCCG
GGCGGCCGCCTGCTGCTGTGCAGCCTGGCCAAGCACGAACACCGCGCCGCGGTGCATGCGTACGGCCACGTCAATCTGGG
GTTTGCTGCCAAGGAGCTGCGCAAGTTCGTTGAAAAAGCCGGGCTGGACGTCTCCAGCCTGGAGACGGTGACACGCGAAA
AACGCCCGCCCCATTTCGAAGTGATCTCGTTGATTGCTGTGAAGCCGGGAATGGGGAATCGGGATTCGGGAATCGCCGAC
CGCAGCGCCGCTGTCTCACGGAGCATCGCATCATGA

Upstream 100 bases:

>100_bases
GCTGGACCCCATTGTAGCGCCAACCATTCGCATGCGTATGTAGTTGACCGCACCTGCCGCCGGCCCGAAAATATCTCCAT
ATCGCGATATAGAGATATTC

Downstream 100 bases:

>100_bases
CGCCTGCAGCACTCCACTCCCCCGTCGCACATGCCCTGCCCTGGCTACGTCCCGAGCGCGCAGCCAAGCTCACCGCCGCG
CTTGCCGAGCGCATCCTCAT

Product: ArsR family transcriptional regulator

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MDLEDWSARLKVFADATRVRLLALLEQEELTVAELSAITRLAQPRVSTHLAKLKEAGLVRDRRAGVSAYYRFDEVSLDPA
QRALWLALSTGSDDPLLRQDAERVAAVLANRAADQNWADSVAGDMERHYSPGRTWEALARTALPLLETGDVLDIASGDGV
LAELVAPHATRYICIDTSARVVAAASERLRKLRNVEVREGDMHALPFPDASFDLVVLMHALTYAAKPAQAVAESARVLRP
GGRLLLCSLAKHEHRAAVHAYGHVNLGFAAKELRKFVEKAGLDVSSLETVTREKRPPHFEVISLIAVKPGMGNRDSGIAD
RSAAVSRSIAS

Sequences:

>Translated_331_residues
MDLEDWSARLKVFADATRVRLLALLEQEELTVAELSAITRLAQPRVSTHLAKLKEAGLVRDRRAGVSAYYRFDEVSLDPA
QRALWLALSTGSDDPLLRQDAERVAAVLANRAADQNWADSVAGDMERHYSPGRTWEALARTALPLLETGDVLDIASGDGV
LAELVAPHATRYICIDTSARVVAAASERLRKLRNVEVREGDMHALPFPDASFDLVVLMHALTYAAKPAQAVAESARVLRP
GGRLLLCSLAKHEHRAAVHAYGHVNLGFAAKELRKFVEKAGLDVSSLETVTREKRPPHFEVISLIAVKPGMGNRDSGIAD
RSAAVSRSIAS
>Mature_331_residues
MDLEDWSARLKVFADATRVRLLALLEQEELTVAELSAITRLAQPRVSTHLAKLKEAGLVRDRRAGVSAYYRFDEVSLDPA
QRALWLALSTGSDDPLLRQDAERVAAVLANRAADQNWADSVAGDMERHYSPGRTWEALARTALPLLETGDVLDIASGDGV
LAELVAPHATRYICIDTSARVVAAASERLRKLRNVEVREGDMHALPFPDASFDLVVLMHALTYAAKPAQAVAESARVLRP
GGRLLLCSLAKHEHRAAVHAYGHVNLGFAAKELRKFVEKAGLDVSSLETVTREKRPPHFEVISLIAVKPGMGNRDSGIAD
RSAAVSRSIAS

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR005149
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08241 Methyltransf_11; PF03551 PadR [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 36046; Mature: 36046

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLEDWSARLKVFADATRVRLLALLEQEELTVAELSAITRLAQPRVSTHLAKLKEAGLVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCH
DRRAGVSAYYRFDEVSLDPAQRALWLALSTGSDDPLLRQDAERVAAVLANRAADQNWADS
HHHCCCHHEEEECCCCCCHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
VAGDMERHYSPGRTWEALARTALPLLETGDVLDIASGDGVLAELVAPHATRYICIDTSAR
HHHHHHHHCCCCCHHHHHHHHHCCHHCCCCEEEECCCCCHHHHHHCCCCCEEEEEECCCH
VVAAASERLRKLRNVEVREGDMHALPFPDASFDLVVLMHALTYAAKPAQAVAESARVLRP
HHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
GGRLLLCSLAKHEHRAAVHAYGHVNLGFAAKELRKFVEKAGLDVSSLETVTREKRPPHFE
CCCEEEEHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHH
VISLIAVKPGMGNRDSGIADRSAAVSRSIAS
HEEEEEECCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MDLEDWSARLKVFADATRVRLLALLEQEELTVAELSAITRLAQPRVSTHLAKLKEAGLVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCH
DRRAGVSAYYRFDEVSLDPAQRALWLALSTGSDDPLLRQDAERVAAVLANRAADQNWADS
HHHCCCHHEEEECCCCCCHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
VAGDMERHYSPGRTWEALARTALPLLETGDVLDIASGDGVLAELVAPHATRYICIDTSAR
HHHHHHHHCCCCCHHHHHHHHHCCHHCCCCEEEECCCCCHHHHHHCCCCCEEEEEECCCH
VVAAASERLRKLRNVEVREGDMHALPFPDASFDLVVLMHALTYAAKPAQAVAESARVLRP
HHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
GGRLLLCSLAKHEHRAAVHAYGHVNLGFAAKELRKFVEKAGLDVSSLETVTREKRPPHFE
CCCEEEEHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHH
VISLIAVKPGMGNRDSGIADRSAAVSRSIAS
HEEEEEECCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2155856 [H]