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The map label for this gene is yafC [H]

Identifier: 78047094

GI number: 78047094

Start: 1735053

End: 1736087

Strand: Reverse

Name: yafC [H]

Synonym: XCV1538

Alternate gene names: 78047094

Gene position: 1736087-1735053 (Counterclockwise)

Preceding gene: 78047100

Following gene: 78047083

Centisome position: 33.53

GC content: 62.32

Gene sequence:

>1035_bases
ATGACTCATGATCTCAACGACACCTTGATCTTCGTCAAGGTGGTCGAACAAGGCAGCTTCATCGCCGCCGCCAATGCGCT
TGGCCTGCCCAAGACCACCGTCAGCCGCAAGGTGCAGGAACTGGAAACCCGGTTGGGTGCGCGCCTGTTGCATCGAACCA
CCCGCCGCATCGGCCTGACCGAAGCCGGCTCGGTGTACCACGAACATTGCCAGCGCATCGCGCGCGAACTGGAAGAAGCC
GAAAGCGCGGTGGGACAGCTGCAATCGGGCCCGCGTGGCTGGCTGCGTTTTACCGTGCCGTATTCGCTGGGCATTACCTG
GATCGCGCCGTTGCTGGGCGAATTCCACGCGCAATACCCGGAAATCCAGCTGGACATGCATCTGGGCAACGAGAAGCTGG
ACCTGATCGGCGGTGAAGCCGATCTGGCATTGCGCGTTGGCGCGCTGCCCGACTCCAATCTGGTGGCGCGCAAGCTCGGC
AGCCTGCGCACCCAGGTGTTCGCCAGCCCCTCCTACATCGAACGCTATGGCGAGCCGCTGCATCCGGACGAATTGCAATT
CCATCGCACGCTCGCCTTGCGCAAGAACCGCAACGTGCACAACAACCGCTTTTTCTGGTCGCTCAGCGACGGCAGCGATG
TACGCGATTTCCCGGTCAATCCGCTGATGGTGGCCAACGATCCGGCCGCGCTCAACGGTGCGGTGTTGTGCGGCGAAGGC
CTGTTGCTGACTGGCGATGTGATGGCCAAACCGTTCGTGCAATCGGGCCTGGTGCGTCGCGTACTGGCCGGTTGGACCGG
GCCTGAGGTGGACTTCAACGCGGTGTTCGCCGGCGGCCGATTGGTGTCGCCGAAAGTGCGGGCGTTCGTGGACTTTTTGG
TGACGCGCATGAATTTCGATGCGGATTACATGATGGCGCAGTGCCCTGCCCGCCTGGCCGCACAAAAGGCCGACAACGAT
GCGAAAGTCGAAGTGGGCGCAGACGCGGAGTTGCGTGCCGAAGGCAAGCGAATCTTGGAAAACGTCACGGCGTAG

Upstream 100 bases:

>100_bases
CGCATAAGTTAGGCTTCAAAGCAGCACTTGATTAGTCCGGATTTAGGGGAATAATCGTCCCGCAAGCGGTCTAATCCCTC
CTGACCCCGGAAGGCATCCC

Downstream 100 bases:

>100_bases
TGCCGGATCGACTGCGCCGGCGGTGGTTGCCGTCTGGCGCAGTCCATAAGTTCATCGATGCAACCCAGTGAATGCATCTC
TGTCACCACACGCGTACAGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTHDLNDTLIFVKVVEQGSFIAAANALGLPKTTVSRKVQELETRLGARLLHRTTRRIGLTEAGSVYHEHCQRIARELEEA
ESAVGQLQSGPRGWLRFTVPYSLGITWIAPLLGEFHAQYPEIQLDMHLGNEKLDLIGGEADLALRVGALPDSNLVARKLG
SLRTQVFASPSYIERYGEPLHPDELQFHRTLALRKNRNVHNNRFFWSLSDGSDVRDFPVNPLMVANDPAALNGAVLCGEG
LLLTGDVMAKPFVQSGLVRRVLAGWTGPEVDFNAVFAGGRLVSPKVRAFVDFLVTRMNFDADYMMAQCPARLAAQKADND
AKVEVGADAELRAEGKRILENVTA

Sequences:

>Translated_344_residues
MTHDLNDTLIFVKVVEQGSFIAAANALGLPKTTVSRKVQELETRLGARLLHRTTRRIGLTEAGSVYHEHCQRIARELEEA
ESAVGQLQSGPRGWLRFTVPYSLGITWIAPLLGEFHAQYPEIQLDMHLGNEKLDLIGGEADLALRVGALPDSNLVARKLG
SLRTQVFASPSYIERYGEPLHPDELQFHRTLALRKNRNVHNNRFFWSLSDGSDVRDFPVNPLMVANDPAALNGAVLCGEG
LLLTGDVMAKPFVQSGLVRRVLAGWTGPEVDFNAVFAGGRLVSPKVRAFVDFLVTRMNFDADYMMAQCPARLAAQKADND
AKVEVGADAELRAEGKRILENVTA
>Mature_343_residues
THDLNDTLIFVKVVEQGSFIAAANALGLPKTTVSRKVQELETRLGARLLHRTTRRIGLTEAGSVYHEHCQRIARELEEAE
SAVGQLQSGPRGWLRFTVPYSLGITWIAPLLGEFHAQYPEIQLDMHLGNEKLDLIGGEADLALRVGALPDSNLVARKLGS
LRTQVFASPSYIERYGEPLHPDELQFHRTLALRKNRNVHNNRFFWSLSDGSDVRDFPVNPLMVANDPAALNGAVLCGEGL
LLTGDVMAKPFVQSGLVRRVLAGWTGPEVDFNAVFAGGRLVSPKVRAFVDFLVTRMNFDADYMMAQCPARLAAQKADNDA
KVEVGADAELRAEGKRILENVTA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=285, Percent_Identity=36.140350877193, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=30.7958477508651, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1789639, Length=232, Percent_Identity=34.4827586206897, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1789440, Length=289, Percent_Identity=29.0657439446367, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1787128, Length=296, Percent_Identity=26.3513513513513, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87081978, Length=299, Percent_Identity=29.0969899665552, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787589, Length=292, Percent_Identity=26.027397260274, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI157672245, Length=125, Percent_Identity=35.2, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1789173, Length=280, Percent_Identity=26.7857142857143, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786448, Length=162, Percent_Identity=30.8641975308642, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787601, Length=120, Percent_Identity=29.1666666666667, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788297, Length=140, Percent_Identity=32.8571428571429, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788748, Length=127, Percent_Identity=33.0708661417323, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787879, Length=160, Percent_Identity=31.875, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788706, Length=174, Percent_Identity=28.735632183908, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37893; Mature: 37762

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHDLNDTLIFVKVVEQGSFIAAANALGLPKTTVSRKVQELETRLGARLLHRTTRRIGLT
CCCCCCCCEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EAGSVYHEHCQRIARELEEAESAVGQLQSGPRGWLRFTVPYSLGITWIAPLLGEFHAQYP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHCCHHHHHHHHHHHHCCCC
EIQLDMHLGNEKLDLIGGEADLALRVGALPDSNLVARKLGSLRTQVFASPSYIERYGEPL
CEEEEEECCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCC
HPDELQFHRTLALRKNRNVHNNRFFWSLSDGSDVRDFPVNPLMVANDPAALNGAVLCGEG
CCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCCCHHCCEEEECCC
LLLTGDVMAKPFVQSGLVRRVLAGWTGPEVDFNAVFAGGRLVSPKVRAFVDFLVTRMNFD
EEEECHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEECCHHHHHHHHHHHHHHCCC
ADYMMAQCPARLAAQKADNDAKVEVGADAELRAEGKRILENVTA
HHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
THDLNDTLIFVKVVEQGSFIAAANALGLPKTTVSRKVQELETRLGARLLHRTTRRIGLT
CCCCCCCEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EAGSVYHEHCQRIARELEEAESAVGQLQSGPRGWLRFTVPYSLGITWIAPLLGEFHAQYP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHCCHHHHHHHHHHHHCCCC
EIQLDMHLGNEKLDLIGGEADLALRVGALPDSNLVARKLGSLRTQVFASPSYIERYGEPL
CEEEEEECCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCC
HPDELQFHRTLALRKNRNVHNNRFFWSLSDGSDVRDFPVNPLMVANDPAALNGAVLCGEG
CCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCCCHHCCEEEECCC
LLLTGDVMAKPFVQSGLVRRVLAGWTGPEVDFNAVFAGGRLVSPKVRAFVDFLVTRMNFD
EEEECHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEECCHHHHHHHHHHHHHHCCC
ADYMMAQCPARLAAQKADNDAKVEVGADAELRAEGKRILENVTA
HHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]