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The map label for this gene is perR [H]

Identifier: 78045079

GI number: 78045079

Start: 1008919

End: 1009320

Strand: Direct

Name: perR [H]

Synonym: CHY_1135

Alternate gene names: 78045079

Gene position: 1008919-1009320 (Clockwise)

Preceding gene: 78043527

Following gene: 78042899

Centisome position: 42.01

GC content: 38.56

Gene sequence:

>402_bases
ATGGCAGCAACCACAAGAATGACCCGACAAAAGAAAGTTATTATTGACATTTTAAAAAATACCAAAAATCATCCAACCGC
CGATTGGATTTACGAACAGGCGCGAAGAATAATTCCCGATATAAGCCTTGGTACCGTTTACCGGAATTTGAGACAATTAA
CCCAATCCGGGGAAATTTTAGAACTGAATTATGGCAGTTCTTACAGCCGTTTTGACGGAAATCCGGTGCCTCATTACCAT
TTTGTATGTGAAAATTGTGGCAGGGTTTACGATGTAGATATGCCCGTCTTAGAGAAGATTGAAAAAGAAGTGGAAAAAAA
GATGGGGTTTTCTGTAAAAAATCATCGTTTAGAATTTTACGGAGTATGCAGTGATTGCCAGCAAAAAGTTAGGGTGGATT
AA

Upstream 100 bases:

>100_bases
AAAACAAGTAATAAACTATTTAAACTACTATGAAAAAATTTTAAAGGGATTATAATAGTAAATAAGAACTATTATCATAA
TTTTTCTTGAGGTGAAACCA

Downstream 100 bases:

>100_bases
ATGAGTAATACCAAACATGCAAAATTATTGGCTTATATTCGCAATTTACCTTCCGGTAGCAAAGTGTCGGTAAGATTGTT
AGCCAAAGAATTAAAGGTTA

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MAATTRMTRQKKVIIDILKNTKNHPTADWIYEQARRIIPDISLGTVYRNLRQLTQSGEILELNYGSSYSRFDGNPVPHYH
FVCENCGRVYDVDMPVLEKIEKEVEKKMGFSVKNHRLEFYGVCSDCQQKVRVD

Sequences:

>Translated_133_residues
MAATTRMTRQKKVIIDILKNTKNHPTADWIYEQARRIIPDISLGTVYRNLRQLTQSGEILELNYGSSYSRFDGNPVPHYH
FVCENCGRVYDVDMPVLEKIEKEVEKKMGFSVKNHRLEFYGVCSDCQQKVRVD
>Mature_132_residues
AATTRMTRQKKVIIDILKNTKNHPTADWIYEQARRIIPDISLGTVYRNLRQLTQSGEILELNYGSSYSRFDGNPVPHYHF
VCENCGRVYDVDMPVLEKIEKEVEKKMGFSVKNHRLEFYGVCSDCQQKVRVD

Specific function: Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=130, Percent_Identity=29.2307692307692, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 15515; Mature: 15384

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATTRMTRQKKVIIDILKNTKNHPTADWIYEQARRIIPDISLGTVYRNLRQLTQSGEIL
CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEE
ELNYGSSYSRFDGNPVPHYHFVCENCGRVYDVDMPVLEKIEKEVEKKMGFSVKNHRLEFY
EECCCCCCCCCCCCCCCHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCEEEE
GVCSDCQQKVRVD
ECCHHHHHHHCCC
>Mature Secondary Structure 
AATTRMTRQKKVIIDILKNTKNHPTADWIYEQARRIIPDISLGTVYRNLRQLTQSGEIL
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEE
ELNYGSSYSRFDGNPVPHYHFVCENCGRVYDVDMPVLEKIEKEVEKKMGFSVKNHRLEFY
EECCCCCCCCCCCCCCCHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCEEEE
GVCSDCQQKVRVD
ECCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202460; 9384377; 9701813; 12100544 [H]