Click here to switch to the map view.

The map label for this gene is hbpA [H]

Identifier: 78044807

GI number: 78044807

Start: 1001280

End: 1002881

Strand: Direct

Name: hbpA [H]

Synonym: CHY_1128

Alternate gene names: 78044807

Gene position: 1001280-1002881 (Clockwise)

Preceding gene: 78044045

Following gene: 78044226

Centisome position: 41.69

GC content: 42.7

Gene sequence:

>1602_bases
TTGCGGAAAATTAAGGTAGTATCCTTTTTGGTTCTCTTAGCTTTTGTATTTACTTTAACTGCTTGCGGGGGAAATACGGC
TAAAAATGAAACTAAAGAAACAAAAGAAAAAGTATTTGTTTTTGCCAAATCCGGTGATCCGGTAGGCCTGGATCCAGCAA
ACGTTACCGATGGGGAGTCAATTTATGTAACCCAGCAAATATTTGAAACCCTGGTGAAATATAAGGATGACAATACCGAA
GTGGTTCCCGGGCTTGCCGAGTCCTGGGAAACTTCTAAAGACGGGCTTACCTGGACTTTTCATCTCCGGAAAGGCGTAAA
GTTCCACGATGGCACACCGTTTAATGCGGAAGCGGTGAAATTTAATTTTGACCGCTGGATGAATAAAAACAATCCTTACC
ATCACGGAGAGTTTGAGTATTACGGTTACATGTTTGGTGGTTATCCTGGAGTGATTAAGGAGGTTAAGGTGGTTGATGAA
TATACCGTCCAAATTACTTTAAAAACTCCTTTAGCTCCCTTCTTATCCAACCTGGCAATGCCCAGTTTTGCTATTTCCAG
TCCTGAAGCTATTAAAAAATATGGGCAGGATTACTTTAAACATCCGGTGGGTACCGGTCCATTTAAATTTGTCGAATGGA
AAAAAGATGACCGGGTGGTTTTAGAGCGGTTTGATGAATACTGGGGAGGAAAAGCCAACTTTGCCAAGGTTATTTTCCGT
ACAATTCCCGACAATTCGGCCCGACTCATGGAATTAAAGTCGGGTAATGTGGATGCAATAACTGACATAAATCCTGATGA
TGTGGAGGCGGTTAAAAATGACCCCAACCTGCAGTTACTGTTACGACCTTCTATGAACGTTGGGTACCTTGCGATGAACA
CTGAAAAGAAACCTTTTGATAATGTTAAAGTTAGACAGGCAATTAACTATGCTATTAATAAAAAAGCGTTAGTGGATGCT
TTTTACGGCGGTCTTGCCAAGCCCGCCAAGAACCCCTTGCCACCGTCCCTTTGGGGTTATAACGATGAAATTCAAGACTA
CGAATATGATCCGGCCAAGGCCAAAGCTCTGTTAGCGGAAGCGGGATATCCCAATGGCTTTACCACCACCTTATGGGCAA
TGCCGGTGGCAAGACCTTACATGCCGCAACCGAAACAAATAGCAGAAGCAATTCAAAAAGACTTAGAGGCGGTTGGAATT
AAAGCAAAAATTGTAACTTATGACTGGGCTACTTACTTAAAGAAAGGTGAAAATGGGGAGCATGACTTATATCTCCTGGG
TTGGACCGGCGACAACGGCGACCCCGATAACTTCCTTTATGTATTGCTGGATAAAGACAATGCCAAGAAAGGTTCTGCTT
CCAACGTTGCTTTCTATAAAAATGATAAAGTTCATGAATTATTAATAAAGGCCCAGCAGGAAAGTGACCAGACCAAGCGT
GCCGAGTACTACAAAGAAGCTCAAGTAATTATTCATAATGATGCTCCTTGGGTTCCCCTGGTTCACTCAACGCCACCGGT
GGCAGCCAGGAAATCGGTTAAAAACTGGATACCTCATCCCACCGGTAGTGAATGTTTCTTTAAAGTTGATAAAGAAGAGT
AA

Upstream 100 bases:

>100_bases
CCATTTGTATAGCGGGGAGGTGAAAAAGGGGATATAGAATATTTTTATAGAGTTTTAGCAAATGCATAAGAAAATAAGCA
AAATGGAGGAGGGAAAAGTT

Downstream 100 bases:

>100_bases
CACGGGTTATAAAGAAGGGGGTAAATAACCCCCTTCTTTTAAAAATGGAGGTATACTGTGTATGGCCAACTATATAGTGA
GAAGATTATTACAACTGATT

Product: oligopeptide/dipeptide ABC transporter peptide-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MRKIKVVSFLVLLAFVFTLTACGGNTAKNETKETKEKVFVFAKSGDPVGLDPANVTDGESIYVTQQIFETLVKYKDDNTE
VVPGLAESWETSKDGLTWTFHLRKGVKFHDGTPFNAEAVKFNFDRWMNKNNPYHHGEFEYYGYMFGGYPGVIKEVKVVDE
YTVQITLKTPLAPFLSNLAMPSFAISSPEAIKKYGQDYFKHPVGTGPFKFVEWKKDDRVVLERFDEYWGGKANFAKVIFR
TIPDNSARLMELKSGNVDAITDINPDDVEAVKNDPNLQLLLRPSMNVGYLAMNTEKKPFDNVKVRQAINYAINKKALVDA
FYGGLAKPAKNPLPPSLWGYNDEIQDYEYDPAKAKALLAEAGYPNGFTTTLWAMPVARPYMPQPKQIAEAIQKDLEAVGI
KAKIVTYDWATYLKKGENGEHDLYLLGWTGDNGDPDNFLYVLLDKDNAKKGSASNVAFYKNDKVHELLIKAQQESDQTKR
AEYYKEAQVIIHNDAPWVPLVHSTPPVAARKSVKNWIPHPTGSECFFKVDKEE

Sequences:

>Translated_533_residues
MRKIKVVSFLVLLAFVFTLTACGGNTAKNETKETKEKVFVFAKSGDPVGLDPANVTDGESIYVTQQIFETLVKYKDDNTE
VVPGLAESWETSKDGLTWTFHLRKGVKFHDGTPFNAEAVKFNFDRWMNKNNPYHHGEFEYYGYMFGGYPGVIKEVKVVDE
YTVQITLKTPLAPFLSNLAMPSFAISSPEAIKKYGQDYFKHPVGTGPFKFVEWKKDDRVVLERFDEYWGGKANFAKVIFR
TIPDNSARLMELKSGNVDAITDINPDDVEAVKNDPNLQLLLRPSMNVGYLAMNTEKKPFDNVKVRQAINYAINKKALVDA
FYGGLAKPAKNPLPPSLWGYNDEIQDYEYDPAKAKALLAEAGYPNGFTTTLWAMPVARPYMPQPKQIAEAIQKDLEAVGI
KAKIVTYDWATYLKKGENGEHDLYLLGWTGDNGDPDNFLYVLLDKDNAKKGSASNVAFYKNDKVHELLIKAQQESDQTKR
AEYYKEAQVIIHNDAPWVPLVHSTPPVAARKSVKNWIPHPTGSECFFKVDKEE
>Mature_533_residues
MRKIKVVSFLVLLAFVFTLTACGGNTAKNETKETKEKVFVFAKSGDPVGLDPANVTDGESIYVTQQIFETLVKYKDDNTE
VVPGLAESWETSKDGLTWTFHLRKGVKFHDGTPFNAEAVKFNFDRWMNKNNPYHHGEFEYYGYMFGGYPGVIKEVKVVDE
YTVQITLKTPLAPFLSNLAMPSFAISSPEAIKKYGQDYFKHPVGTGPFKFVEWKKDDRVVLERFDEYWGGKANFAKVIFR
TIPDNSARLMELKSGNVDAITDINPDDVEAVKNDPNLQLLLRPSMNVGYLAMNTEKKPFDNVKVRQAINYAINKKALVDA
FYGGLAKPAKNPLPPSLWGYNDEIQDYEYDPAKAKALLAEAGYPNGFTTTLWAMPVARPYMPQPKQIAEAIQKDLEAVGI
KAKIVTYDWATYLKKGENGEHDLYLLGWTGDNGDPDNFLYVLLDKDNAKKGSASNVAFYKNDKVHELLIKAQQESDQTKR
AEYYKEAQVIIHNDAPWVPLVHSTPPVAARKSVKNWIPHPTGSECFFKVDKEE

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=514, Percent_Identity=44.9416342412451, Blast_Score=438, Evalue=1e-124,
Organism=Escherichia coli, GI1787052, Length=511, Percent_Identity=35.0293542074364, Blast_Score=277, Evalue=1e-75,
Organism=Escherichia coli, GI1787551, Length=551, Percent_Identity=32.1234119782214, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1787762, Length=498, Percent_Identity=31.9277108433735, Blast_Score=241, Evalue=9e-65,
Organism=Escherichia coli, GI1789887, Length=510, Percent_Identity=29.8039215686275, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1787495, Length=545, Percent_Identity=25.8715596330275, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1789397, Length=491, Percent_Identity=27.2912423625255, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI87081878, Length=525, Percent_Identity=25.9047619047619, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI87082063, Length=292, Percent_Identity=24.6575342465753, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60155; Mature: 60155

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIKVVSFLVLLAFVFTLTACGGNTAKNETKETKEKVFVFAKSGDPVGLDPANVTDGES
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCEEEEEEECCCCCCCCCCCCCCCCCE
IYVTQQIFETLVKYKDDNTEVVPGLAESWETSKDGLTWTFHLRKGVKFHDGTPFNAEAVK
EEEHHHHHHHHHHCCCCCCEECCCCHHHCCCCCCCEEEEEEECCCCEECCCCCCCCEEEE
FNFDRWMNKNNPYHHGEFEYYGYMFGGYPGVIKEVKVVDEYTVQITLKTPLAPFLSNLAM
EEHHHHCCCCCCCCCCCEEEEEEEECCCCCHHHHEEEEEEEEEEEEECCCHHHHHHHHCC
PSFAISSPEAIKKYGQDYFKHPVGTGPFKFVEWKKDDRVVLERFDEYWGGKANFAKVIFR
CCEECCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHH
TIPDNSARLMELKSGNVDAITDINPDDVEAVKNDPNLQLLLRPSMNVGYLAMNTEKKPFD
HCCCCCCEEEEECCCCEEEEECCCCHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCC
NVKVRQAINYAINKKALVDAFYGGLAKPAKNPLPPSLWGYNDEIQDYEYDPAKAKALLAE
CHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AGYPNGFTTTLWAMPVARPYMPQPKQIAEAIQKDLEAVGIKAKIVTYDWATYLKKGENGE
CCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEEHHHHHHCCCCCC
HDLYLLGWTGDNGDPDNFLYVLLDKDNAKKGSASNVAFYKNDKVHELLIKAQQESDQTKR
CEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCHHHH
AEYYKEAQVIIHNDAPWVPLVHSTPPVAARKSVKNWIPHPTGSECFFKVDKEE
HHHHCCCEEEEECCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEECCCC
>Mature Secondary Structure
MRKIKVVSFLVLLAFVFTLTACGGNTAKNETKETKEKVFVFAKSGDPVGLDPANVTDGES
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCEEEEEEECCCCCCCCCCCCCCCCCE
IYVTQQIFETLVKYKDDNTEVVPGLAESWETSKDGLTWTFHLRKGVKFHDGTPFNAEAVK
EEEHHHHHHHHHHCCCCCCEECCCCHHHCCCCCCCEEEEEEECCCCEECCCCCCCCEEEE
FNFDRWMNKNNPYHHGEFEYYGYMFGGYPGVIKEVKVVDEYTVQITLKTPLAPFLSNLAM
EEHHHHCCCCCCCCCCCEEEEEEEECCCCCHHHHEEEEEEEEEEEEECCCHHHHHHHHCC
PSFAISSPEAIKKYGQDYFKHPVGTGPFKFVEWKKDDRVVLERFDEYWGGKANFAKVIFR
CCEECCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHH
TIPDNSARLMELKSGNVDAITDINPDDVEAVKNDPNLQLLLRPSMNVGYLAMNTEKKPFD
HCCCCCCEEEEECCCCEEEEECCCCHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCC
NVKVRQAINYAINKKALVDAFYGGLAKPAKNPLPPSLWGYNDEIQDYEYDPAKAKALLAE
CHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AGYPNGFTTTLWAMPVARPYMPQPKQIAEAIQKDLEAVGIKAKIVTYDWATYLKKGENGE
CCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEEHHHHHHCCCCCC
HDLYLLGWTGDNGDPDNFLYVLLDKDNAKKGSASNVAFYKNDKVHELLIKAQQESDQTKR
CEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCHHHH
AEYYKEAQVIIHNDAPWVPLVHSTPPVAARKSVKNWIPHPTGSECFFKVDKEE
HHHHCCCEEEEECCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]