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The map label for this gene is dsbD [H]

Identifier: 78044353

GI number: 78044353

Start: 969504

End: 970691

Strand: Direct

Name: dsbD [H]

Synonym: CHY_1095

Alternate gene names: 78044353

Gene position: 969504-970691 (Clockwise)

Preceding gene: 78043914

Following gene: 78045143

Centisome position: 40.37

GC content: 42.93

Gene sequence:

>1188_bases
ATGGAAAAGAAAAGTACTATTGCTTTAATTGTGGTATTTGTCATTGCCCTTTTAGCCTTTGGAGTGTATTACGCTACTAA
CCGGGAATTAGGCTCGCCGGCTAATAGCGGCAATGTAATTGATCAGTACAATGAGGCTTTAAAAAACCATGAACCTTTTT
TATTAGAGTTTTCCGGGGCAACCTGACCTACCTGTGCGCAAATGGCACCGGTGGTGCAGGAATTAAAGAAAGAATACGAA
GGACGGATGCGGGTAATTGTAGCGGAAGTTAGTCGTCAGGATAGCCAACAGTTAGCAGCAAAATTTGGTATCCAGTACGT
CCCAACGTTTATTGTAGTTGATCAAAACGGGAATATTGTCCCCTGGACTGATGCCCAGGGCAATCAAATGCCGATGTTTG
TTGGCGGGCTTACTAAGGAAGAGTTAAAAGCCCAGATGGATAAAGTGGCTTTAAAGGAAAAAAAAACCCCTGAATTAAAT
GATTCGGGGAAGAAAAAATCTTTTGCCCAAACGCTTGCGGATAAGCTTCCAGGGTTACTGGGGGATTCAAAGCTTTTAGC
GCTTTTTGTTGTTTTTCTTGGGGGGATTGCTACCAGTTTTACCCCTTGTATCTTAGGTATGATTCCGCTTATTATCGGTT
ACACCGGTGGTTATGCCGGGCGGTCACCGGCCAAAGGATTTATTTACTCGCTATTTTTTGTCCTGGGTCTTGCTACGACT
CTTACCCTTTTGGGAGTTGGAATTGGGGTTTTAGGAACTTTTATCAAAAGCCGGTTATTTGCTTTTAATTTTATTCTGGG
GATAGTGGCCATTTTAATGGGATTTGCGGTGATGGGCTTTTATACGATAAATCTTCCTGGCTTAAAAAGGATGCCGGTTA
AGGGCACCGGACTTTTTTCTTCGTATTTAATGGGCTTGTTCTTTGGCTTATCCGCCAGCCCCTGTGCCACGCCGGTTTTA
ATTGTTATTGTAACTTATGCGCTGGCTAAAGCATCGCCTTTATTTGGCGGAGCGCTCCTGTTTTCCTACAGTTTTGGCCA
TGGCCTACCCTTAATCTTAGCCGGTACCTTTTCTGCCTTTTTGGGTAAGATTACTTCCTTAGGACGGTACGGGGAAATAA
TTAATTATATTTTTGGCGGGATACTTGTGTTGTATGGGTTGTACCTTTTGTTTGGAAGATTATTATAG

Upstream 100 bases:

>100_bases
TCCTGTTTAAATAAACAAGTGAAAAATTTTAGTCACAGAAAAAATAAAATATGGTATAATTAAAAAAAGTAAATTAATTA
AATCAATAGGCGGGGTGGAG

Downstream 100 bases:

>100_bases
CAAAATAAGTTCAAAAAGGCCGGAATGGAAATCCGGCCTTTTATGTTTTAGGGGTAGGAAAACTTATTGGTTGGCGTGCT
CTAAAATAATTTTTTCCAGT

Product: thioredoxin domain-containing protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MEKKSTIALIVVFVIALLAFGVYYATNRELGSPANSGNVIDQYNEALKNHEPFLLEFSGATUPTCAQMAPVVQELKKEYE
GRMRVIVAEVSRQDSQQLAAKFGIQYVPTFIVVDQNGNIVPWTDAQGNQMPMFVGGLTKEELKAQMDKVALKEKKTPELN
DSGKKKSFAQTLADKLPGLLGDSKLLALFVVFLGGIATSFTPCILGMIPLIIGYTGGYAGRSPAKGFIYSLFFVLGLATT
LTLLGVGIGVLGTFIKSRLFAFNFILGIVAILMGFAVMGFYTINLPGLKRMPVKGTGLFSSYLMGLFFGLSASPCATPVL
IVIVTYALAKASPLFGGALLFSYSFGHGLPLILAGTFSAFLGKITSLGRYGEIINYIFGGILVLYGLYLLFGRLL

Sequences:

>Translated_395_residues
MEKKSTIALIVVFVIALLAFGVYYATNRELGSPANSGNVIDQYNEALKNHEPFLLEFSGAT*PTCAQMAPVVQELKKEYE
GRMRVIVAEVSRQDSQQLAAKFGIQYVPTFIVVDQNGNIVPWTDAQGNQMPMFVGGLTKEELKAQMDKVALKEKKTPELN
DSGKKKSFAQTLADKLPGLLGDSKLLALFVVFLGGIATSFTPCILGMIPLIIGYTGGYAGRSPAKGFIYSLFFVLGLATT
LTLLGVGIGVLGTFIKSRLFAFNFILGIVAILMGFAVMGFYTINLPGLKRMPVKGTGLFSSYLMGLFFGLSASPCATPVL
IVIVTYALAKASPLFGGALLFSYSFGHGLPLILAGTFSAFLGKITSLGRYGEIINYIFGGILVLYGLYLLFGRLL
>Mature_395_residues
MEKKSTIALIVVFVIALLAFGVYYATNRELGSPANSGNVIDQYNEALKNHEPFLLEFSGAT*PTCAQMAPVVQELKKEYE
GRMRVIVAEVSRQDSQQLAAKFGIQYVPTFIVVDQNGNIVPWTDAQGNQMPMFVGGLTKEELKAQMDKVALKEKKTPELN
DSGKKKSFAQTLADKLPGLLGDSKLLALFVVFLGGIATSFTPCILGMIPLIIGYTGGYAGRSPAKGFIYSLFFVLGLATT
LTLLGVGIGVLGTFIKSRLFAFNFILGIVAILMGFAVMGFYTINLPGLKRMPVKGTGLFSSYLMGLFFGLSASPCATPVL
IVIVTYALAKASPLFGGALLFSYSFGHGLPLILAGTFSAFLGKITSLGRYGEIINYIFGGILVLYGLYLLFGRLL

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=218, Percent_Identity=31.1926605504587, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 42368; Mature: 42368

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKSTIALIVVFVIALLAFGVYYATNRELGSPANSGNVIDQYNEALKNHEPFLLEFSGA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCC
TPTCAQMAPVVQELKKEYEGRMRVIVAEVSRQDSQQLAAKFGIQYVPTFIVVDQNGNIVP
CCHHHHHHHHHHHHHHHHCCHHEEEHHHHHCCHHHHHHHHHCHHEECEEEEEECCCCEEE
WTDAQGNQMPMFVGGLTKEELKAQMDKVALKEKKTPELNDSGKKKSFAQTLADKLPGLLG
CCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCC
DSKLLALFVVFLGGIATSFTPCILGMIPLIIGYTGGYAGRSPAKGFIYSLFFVLGLATTL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TLLGVGIGVLGTFIKSRLFAFNFILGIVAILMGFAVMGFYTINLPGLKRMPVKGTGLFSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHH
YLMGLFFGLSASPCATPVLIVIVTYALAKASPLFGGALLFSYSFGHGLPLILAGTFSAFL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHH
GKITSLGRYGEIINYIFGGILVLYGLYLLFGRLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKKSTIALIVVFVIALLAFGVYYATNRELGSPANSGNVIDQYNEALKNHEPFLLEFSGA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCC
TPTCAQMAPVVQELKKEYEGRMRVIVAEVSRQDSQQLAAKFGIQYVPTFIVVDQNGNIVP
CCHHHHHHHHHHHHHHHHCCHHEEEHHHHHCCHHHHHHHHHCHHEECEEEEEECCCCEEE
WTDAQGNQMPMFVGGLTKEELKAQMDKVALKEKKTPELNDSGKKKSFAQTLADKLPGLLG
CCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCC
DSKLLALFVVFLGGIATSFTPCILGMIPLIIGYTGGYAGRSPAKGFIYSLFFVLGLATTL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TLLGVGIGVLGTFIKSRLFAFNFILGIVAILMGFAVMGFYTINLPGLKRMPVKGTGLFSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHH
YLMGLFFGLSASPCATPVLIVIVTYALAKASPLFGGALLFSYSFGHGLPLILAGTFSAFL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHH
GKITSLGRYGEIINYIFGGILVLYGLYLLFGRLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA