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The map label for this gene is hgdA [H]

Identifier: 78043095

GI number: 78043095

Start: 1053400

End: 1054608

Strand: Direct

Name: hgdA [H]

Synonym: CHY_1184

Alternate gene names: 78043095

Gene position: 1053400-1054608 (Clockwise)

Preceding gene: 78044667

Following gene: 78045224

Centisome position: 43.86

GC content: 31.02

Gene sequence:

>1209_bases
ATGGATAAACCTGAAAAAATAAATAAACTTATAAATTTTGGACTTACTACTGCTTATTACTATGTAAGCATTTTTAAAGA
TAAAAGGGGACCCAATTCTTTACATTATCTAACTAAATACTGTATAAAAAGTATAAAAGATTCATTAGAAAATCCTCAAA
ATTCTGCCTGGGTAAACATTTTTTCACCCTGTGAGTTTTTAATTGCTCTGGATATAAAGCCCTTATTTATTGAAGCATAT
TCTTCTTTTATGTCAGGTTTTTTTATTGAAGATTATCTTATTGATACTGCCGAATCCAGGGGGATAGCAAATACTTTATG
CAGTTATCATAAAACTTTTATCGGTGCCAATGAGCTTAAAATTCTTAAAAAGCCTGAATTTATGCTAACTACTTCCAGCA
TTTGTGATGCAAACGTACCTACCTTCAGGTATCTTTCTAAAAAACAAAACGTTCCCTTATATATTATCGATGTGCCTTAT
AAGTACTCTAAAGAAGCCGTAGCCTATGTAAAAAACCAGCTTATAGAAATGGTGGAAAATCTTGAAGAAGTTTTTAAGAG
AAAGCTTGATCTTGATAAATTAAGGGAAGTTGTAAAAATTGAAAATAAGACAAGAACCCTCATAAATAAGTATTTAAATT
ATTTAAAAGAAAAAACCCTTTTGGTTCCCATGACTTTTGAAATGTATATGCTTTTTGCATCACATATATTTATTGGGAGC
AAAGAGATGTTAAAGTTTTATGAAATGCTGCTTGACGATATAAAAAATGCTCCCCCAAGAAGTGGAAAAAGTATATTTTT
TGTCCACCTTCTCCCTATATTTGAGAAAAATTTTCAAGATTATTTTAATTTTAGTAATAAATTTCATATTGCTGGAAGTG
ATTTAAATTTTGATTATCTTGACGAAATTGACGAAAAGGACCCTTTTCGCGGAATTGCTGAAAAACTTATTTTAAATACT
TTCAATGGTGAAATGGAGAGAAAAGTTACCAGAATTAGAGAATTAATTGAAAAGATAAAACCAGACGGAATAATACAGTT
TTGCCACCTTGGCTGCAAGCAGTCCATAGGTGGAACATTTATCATTAAAGATCTTGCAACAAAAATGGGTATCCCATTTC
TTTATTTAGATGGCGACTGTGTAGATAAAAGAAATAACCAGGTGGGGCAGAACAGGACAAGGCTGGAAGCTTTTCTTGAA
ATGCTTTAG

Upstream 100 bases:

>100_bases
AAGCCCGGGAACGGATAAATTGGCGAAAAAAACTTGGAGATAAGAGGCAGTGATGAAAATGGATGTAGTTAGGTTTTACA
GCAATATTATTAAAAGAAAT

Downstream 100 bases:

>100_bases
TAATGCCCGTAGGGGGTGAAAACTTGGTAGGTTACGTTTGTAAATATACTCCGGTGGAAATTATCGAAGCCTTTGGAGAA
AAACCGGTAAGGATTGAATC

Product: putative (R)-2-hydroxyglutaryl-CoA dehydratase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MDKPEKINKLINFGLTTAYYYVSIFKDKRGPNSLHYLTKYCIKSIKDSLENPQNSAWVNIFSPCEFLIALDIKPLFIEAY
SSFMSGFFIEDYLIDTAESRGIANTLCSYHKTFIGANELKILKKPEFMLTTSSICDANVPTFRYLSKKQNVPLYIIDVPY
KYSKEAVAYVKNQLIEMVENLEEVFKRKLDLDKLREVVKIENKTRTLINKYLNYLKEKTLLVPMTFEMYMLFASHIFIGS
KEMLKFYEMLLDDIKNAPPRSGKSIFFVHLLPIFEKNFQDYFNFSNKFHIAGSDLNFDYLDEIDEKDPFRGIAEKLILNT
FNGEMERKVTRIRELIEKIKPDGIIQFCHLGCKQSIGGTFIIKDLATKMGIPFLYLDGDCVDKRNNQVGQNRTRLEAFLE
ML

Sequences:

>Translated_402_residues
MDKPEKINKLINFGLTTAYYYVSIFKDKRGPNSLHYLTKYCIKSIKDSLENPQNSAWVNIFSPCEFLIALDIKPLFIEAY
SSFMSGFFIEDYLIDTAESRGIANTLCSYHKTFIGANELKILKKPEFMLTTSSICDANVPTFRYLSKKQNVPLYIIDVPY
KYSKEAVAYVKNQLIEMVENLEEVFKRKLDLDKLREVVKIENKTRTLINKYLNYLKEKTLLVPMTFEMYMLFASHIFIGS
KEMLKFYEMLLDDIKNAPPRSGKSIFFVHLLPIFEKNFQDYFNFSNKFHIAGSDLNFDYLDEIDEKDPFRGIAEKLILNT
FNGEMERKVTRIRELIEKIKPDGIIQFCHLGCKQSIGGTFIIKDLATKMGIPFLYLDGDCVDKRNNQVGQNRTRLEAFLE
ML
>Mature_402_residues
MDKPEKINKLINFGLTTAYYYVSIFKDKRGPNSLHYLTKYCIKSIKDSLENPQNSAWVNIFSPCEFLIALDIKPLFIEAY
SSFMSGFFIEDYLIDTAESRGIANTLCSYHKTFIGANELKILKKPEFMLTTSSICDANVPTFRYLSKKQNVPLYIIDVPY
KYSKEAVAYVKNQLIEMVENLEEVFKRKLDLDKLREVVKIENKTRTLINKYLNYLKEKTLLVPMTFEMYMLFASHIFIGS
KEMLKFYEMLLDDIKNAPPRSGKSIFFVHLLPIFEKNFQDYFNFSNKFHIAGSDLNFDYLDEIDEKDPFRGIAEKLILNT
FNGEMERKVTRIRELIEKIKPDGIIQFCHLGCKQSIGGTFIIKDLATKMGIPFLYLDGDCVDKRNNQVGQNRTRLEAFLE
ML

Specific function: Catalyzes the reversible dehydration of 2- hydroxyglutaryl-CoA to glutaconyl-CoA. This is a key step in the fermentation of glutamate. It is activated by hgdC [H]

COG id: COG1775

COG function: function code E; Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010327 [H]

Pfam domain/function: PF06050 HGD-D [H]

EC number: NA

Molecular weight: Translated: 46862; Mature: 46862

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKPEKINKLINFGLTTAYYYVSIFKDKRGPNSLHYLTKYCIKSIKDSLENPQNSAWVNI
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEE
FSPCEFLIALDIKPLFIEAYSSFMSGFFIEDYLIDTAESRGIANTLCSYHKTFIGANELK
ECHHEEEHEECCHHHHHHHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHHHHHCCCCHHH
ILKKPEFMLTTSSICDANVPTFRYLSKKQNVPLYIIDVPYKYSKEAVAYVKNQLIEMVEN
EEECCCEEEEEHHHCCCCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
LEEVFKRKLDLDKLREVVKIENKTRTLINKYLNYLKEKTLLVPMTFEMYMLFASHIFIGS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCC
KEMLKFYEMLLDDIKNAPPRSGKSIFFVHLLPIFEKNFQDYFNFSNKFHIAGSDLNFDYL
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
DEIDEKDPFRGIAEKLILNTFNGEMERKVTRIRELIEKIKPDGIIQFCHLGCKQSIGGTF
HHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEE
IIKDLATKMGIPFLYLDGDCVDKRNNQVGQNRTRLEAFLEML
HHHHHHHHHCCCEEEECCCHHCCCCCCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MDKPEKINKLINFGLTTAYYYVSIFKDKRGPNSLHYLTKYCIKSIKDSLENPQNSAWVNI
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEE
FSPCEFLIALDIKPLFIEAYSSFMSGFFIEDYLIDTAESRGIANTLCSYHKTFIGANELK
ECHHEEEHEECCHHHHHHHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHHHHHCCCCHHH
ILKKPEFMLTTSSICDANVPTFRYLSKKQNVPLYIIDVPYKYSKEAVAYVKNQLIEMVEN
EEECCCEEEEEHHHCCCCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
LEEVFKRKLDLDKLREVVKIENKTRTLINKYLNYLKEKTLLVPMTFEMYMLFASHIFIGS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCC
KEMLKFYEMLLDDIKNAPPRSGKSIFFVHLLPIFEKNFQDYFNFSNKFHIAGSDLNFDYL
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
DEIDEKDPFRGIAEKLILNTFNGEMERKVTRIRELIEKIKPDGIIQFCHLGCKQSIGGTF
HHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEE
IIKDLATKMGIPFLYLDGDCVDKRNNQVGQNRTRLEAFLEML
HHHHHHHHHCCCEEEECCCHHCCCCCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2659350; 3691501; 8365476; 11106419 [H]