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The map label for this gene is ubiB [C]

Identifier: 78042754

GI number: 78042754

Start: 1103112

End: 1104695

Strand: Direct

Name: ubiB [C]

Synonym: CHY_1237

Alternate gene names: 78042754

Gene position: 1103112-1104695 (Clockwise)

Preceding gene: 78044663

Following gene: 78043445

Centisome position: 45.93

GC content: 34.47

Gene sequence:

>1584_bases
ATGCAAGAATCCCAAAGGCTTGGAGAAATTCTTCGGGTTTTAAGTAAATATGGGCTAACGGTCCTGAAAAACAAGTTACA
AAAACAAGTTGTATTAACGGATTCCCAGATCCTACAACTCTTCACCGATTTAGGCCCTACGTTTATAAAATTTGGGCAGT
TTTTAAGTACGCGCCCTGACCTGGTAGACGAAAGGTTTATAACAGTACTTCGTAATTTACAGGATAACGTACCAGCGGTT
TCCTTTACGGTGTGCAAAAAATTTATTGAAGAAACTTTTGCGGTAAACTACTTTACTAACTTTAAGGAAATTGACCCCCG
ACCTATAGCCAGTGCATCAATTGCTCAGGTTTATTTCGGAATTTTAAAAAGTGGGGAAAAAGTTGTTCTTAAAATTAAAA
GACCAGATATAGAAGAAACTATAAAAACCGATTTGGAAGTTATCAAAAAGTATTTACTACCACAATTAAGAGCTTTAGGA
TTTATTTCCCATTTCGATTTGAACAAGATTTTCAATCTATTTGAAATCAAACTTAAAGAAGAATTAGATTTTTTAAACGA
ACTGCAAAACTTAAAAATTTTTCACAGGGCTCTTAAAAATTATGAAGACCTGATAATTCCGAAAGCATTTAAGGAATTAT
CGGGACGGAATGTTTTAGTAATGGAGTACGTGGACGGCAATCTTTTAAAAAATTTTTTAGAGCAAAAGGTATATTACCCA
ACCTTAGGAGAGAAGCTAATCCATAACTTTTGCCGTCTTTTATTTTGGGAAAGGATATTTCATGCAGACCCTCATCCGGG
TAATATTATTTTTACCAAAAATAAAAAGCTTTGCTTTTTGGACTTGGGTGCCGTTGGCTTTGTAGACCAGAGAACCGTTG
AAATCCTGGCCGAACTATTTATTTATTTATGTGAAAAAAATTTAAATGGAGTAATTAATTTAATTTTTCGCCTGGGACAA
TACCGGGGAGAAATTGATGAGTTTACTTTTTACCAGGAAATGTACAAGTTACTTGAACTCGTTTCGGAAGTGGGTAAGGG
TGAGGTCTTGGCGGGAAAGCTAATTCTTGATATTATTAAAATTAGTATCAAGTATGGTATTAATTTGCCGGTAAATCTTG
TTTATATCGGTAAAGCTGCGTTAACTCTGGAAAGTACTGCTATTTCCCTGGGAACACGTTTTAATTTTTTTGAAATCGCT
AAAAAATATGGCGAAGAAACTTTAATAAAAACTACCTTAAACACATTGGCACCGTCCGATATAGCTTTAAATTTATACAG
GTACTTGGAAATTAAGGGAAAATTACCGTTGCTTTTCTTTTCAATCTTAAAAAAGTTTGATGAGGGAACCTTCCAGGTAA
TTTTTCGGCATGCCGGATTAGAAATCTTCATCAAAGCTTTGGACAGGACTTCAATGAGAATTACTTTTGGGTTAATAATT
TCTTCATTACTTATTGCTTCAGGTTTAATTGTAGCTGCCGATGGCCGGCTTTTGCAAACTTTAGGGACTGCCACCTACAT
ATTATCAATACTTGCCGCCGGTTATTTAATTTATTTAATTTTTAAGTCAGGAAAATGGCATTAA

Upstream 100 bases:

>100_bases
ACCGGTGGATTTAGATATTCGCCTGAGGAAAACCCGAGGAATGTAGAAAAATAATTAGGGAAAACTATTACTGTTTAAAA
AAAACAACGGGCTGATTGAC

Downstream 100 bases:

>100_bases
ACGAAGGGGGAGATTTATGAGTTCCGAAGTTTATTTTGTGAATGTGCGTGCCCAGAAAGGAGCAAGTTTACTGGAAAAAC
TGGAACGCTTGATTGACCGG

Product: ABC1 family protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MQESQRLGEILRVLSKYGLTVLKNKLQKQVVLTDSQILQLFTDLGPTFIKFGQFLSTRPDLVDERFITVLRNLQDNVPAV
SFTVCKKFIEETFAVNYFTNFKEIDPRPIASASIAQVYFGILKSGEKVVLKIKRPDIEETIKTDLEVIKKYLLPQLRALG
FISHFDLNKIFNLFEIKLKEELDFLNELQNLKIFHRALKNYEDLIIPKAFKELSGRNVLVMEYVDGNLLKNFLEQKVYYP
TLGEKLIHNFCRLLFWERIFHADPHPGNIIFTKNKKLCFLDLGAVGFVDQRTVEILAELFIYLCEKNLNGVINLIFRLGQ
YRGEIDEFTFYQEMYKLLELVSEVGKGEVLAGKLILDIIKISIKYGINLPVNLVYIGKAALTLESTAISLGTRFNFFEIA
KKYGEETLIKTTLNTLAPSDIALNLYRYLEIKGKLPLLFFSILKKFDEGTFQVIFRHAGLEIFIKALDRTSMRITFGLII
SSLLIASGLIVAADGRLLQTLGTATYILSILAAGYLIYLIFKSGKWH

Sequences:

>Translated_527_residues
MQESQRLGEILRVLSKYGLTVLKNKLQKQVVLTDSQILQLFTDLGPTFIKFGQFLSTRPDLVDERFITVLRNLQDNVPAV
SFTVCKKFIEETFAVNYFTNFKEIDPRPIASASIAQVYFGILKSGEKVVLKIKRPDIEETIKTDLEVIKKYLLPQLRALG
FISHFDLNKIFNLFEIKLKEELDFLNELQNLKIFHRALKNYEDLIIPKAFKELSGRNVLVMEYVDGNLLKNFLEQKVYYP
TLGEKLIHNFCRLLFWERIFHADPHPGNIIFTKNKKLCFLDLGAVGFVDQRTVEILAELFIYLCEKNLNGVINLIFRLGQ
YRGEIDEFTFYQEMYKLLELVSEVGKGEVLAGKLILDIIKISIKYGINLPVNLVYIGKAALTLESTAISLGTRFNFFEIA
KKYGEETLIKTTLNTLAPSDIALNLYRYLEIKGKLPLLFFSILKKFDEGTFQVIFRHAGLEIFIKALDRTSMRITFGLII
SSLLIASGLIVAADGRLLQTLGTATYILSILAAGYLIYLIFKSGKWH
>Mature_527_residues
MQESQRLGEILRVLSKYGLTVLKNKLQKQVVLTDSQILQLFTDLGPTFIKFGQFLSTRPDLVDERFITVLRNLQDNVPAV
SFTVCKKFIEETFAVNYFTNFKEIDPRPIASASIAQVYFGILKSGEKVVLKIKRPDIEETIKTDLEVIKKYLLPQLRALG
FISHFDLNKIFNLFEIKLKEELDFLNELQNLKIFHRALKNYEDLIIPKAFKELSGRNVLVMEYVDGNLLKNFLEQKVYYP
TLGEKLIHNFCRLLFWERIFHADPHPGNIIFTKNKKLCFLDLGAVGFVDQRTVEILAELFIYLCEKNLNGVINLIFRLGQ
YRGEIDEFTFYQEMYKLLELVSEVGKGEVLAGKLILDIIKISIKYGINLPVNLVYIGKAALTLESTAISLGTRFNFFEIA
KKYGEETLIKTTLNTLAPSDIALNLYRYLEIKGKLPLLFFSILKKFDEGTFQVIFRHAGLEIFIKALDRTSMRITFGLII
SSLLIASGLIVAADGRLLQTLGTATYILSILAAGYLIYLIFKSGKWH

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=237, Percent_Identity=27.8481012658228, Blast_Score=106, Evalue=7e-23,
Organism=Homo sapiens, GI41393593, Length=263, Percent_Identity=26.2357414448669, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI217035081, Length=183, Percent_Identity=27.8688524590164, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI2367309, Length=419, Percent_Identity=29.5942720763723, Blast_Score=137, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17559152, Length=298, Percent_Identity=24.496644295302, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI32565180, Length=256, Percent_Identity=25, Blast_Score=86, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6325148, Length=256, Percent_Identity=28.90625, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6321319, Length=314, Percent_Identity=26.1146496815287, Blast_Score=90, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6323282, Length=308, Percent_Identity=23.3766233766234, Blast_Score=73, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24662575, Length=235, Percent_Identity=29.3617021276596, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI22024280, Length=241, Percent_Identity=26.9709543568465, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI18859849, Length=280, Percent_Identity=21.4285714285714, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 60400; Mature: 60400

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQESQRLGEILRVLSKYGLTVLKNKLQKQVVLTDSQILQLFTDLGPTFIKFGQFLSTRPD
CCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHCCCCC
LVDERFITVLRNLQDNVPAVSFTVCKKFIEETFAVNYFTNFKEIDPRPIASASIAQVYFG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
ILKSGEKVVLKIKRPDIEETIKTDLEVIKKYLLPQLRALGFISHFDLNKIFNLFEIKLKE
HHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ELDFLNELQNLKIFHRALKNYEDLIIPKAFKELSGRNVLVMEYVDGNLLKNFLEQKVYYP
HHHHHHHHHHHHHHHHHHHCHHHHHCHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCC
TLGEKLIHNFCRLLFWERIFHADPHPGNIIFTKNKKLCFLDLGAVGFVDQRTVEILAELF
CHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHH
IYLCEKNLNGVINLIFRLGQYRGEIDEFTFYQEMYKLLELVSEVGKGEVLAGKLILDIIK
HHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ISIKYGINLPVNLVYIGKAALTLESTAISLGTRFNFFEIAKKYGEETLIKTTLNTLAPSD
HHHHCCCCCCEEEEEECCCCEEEHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCCH
IALNLYRYLEIKGKLPLLFFSILKKFDEGTFQVIFRHAGLEIFIKALDRTSMRITFGLII
HHHHHHHHHEECCCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHH
SSLLIASGLIVAADGRLLQTLGTATYILSILAAGYLIYLIFKSGKWH
HHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQESQRLGEILRVLSKYGLTVLKNKLQKQVVLTDSQILQLFTDLGPTFIKFGQFLSTRPD
CCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHCCCCC
LVDERFITVLRNLQDNVPAVSFTVCKKFIEETFAVNYFTNFKEIDPRPIASASIAQVYFG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
ILKSGEKVVLKIKRPDIEETIKTDLEVIKKYLLPQLRALGFISHFDLNKIFNLFEIKLKE
HHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ELDFLNELQNLKIFHRALKNYEDLIIPKAFKELSGRNVLVMEYVDGNLLKNFLEQKVYYP
HHHHHHHHHHHHHHHHHHHCHHHHHCHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCC
TLGEKLIHNFCRLLFWERIFHADPHPGNIIFTKNKKLCFLDLGAVGFVDQRTVEILAELF
CHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHH
IYLCEKNLNGVINLIFRLGQYRGEIDEFTFYQEMYKLLELVSEVGKGEVLAGKLILDIIK
HHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ISIKYGINLPVNLVYIGKAALTLESTAISLGTRFNFFEIAKKYGEETLIKTTLNTLAPSD
HHHHCCCCCCEEEEEECCCCEEEHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCCH
IALNLYRYLEIKGKLPLLFFSILKKFDEGTFQVIFRHAGLEIFIKALDRTSMRITFGLII
HHHHHHHHHEECCCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHH
SSLLIASGLIVAADGRLLQTLGTATYILSILAAGYLIYLIFKSGKWH
HHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA