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The map label for this gene is flhF [H]

Identifier: 78042670

GI number: 78042670

Start: 891967

End: 893019

Strand: Direct

Name: flhF [H]

Synonym: CHY_1010

Alternate gene names: 78042670

Gene position: 891967-893019 (Clockwise)

Preceding gene: 78044126

Following gene: 78045153

Centisome position: 37.14

GC content: 44.44

Gene sequence:

>1053_bases
GTGAAGATCAAAAAGTATACGGCCAGAGATATGGCGGAAGCCCTCCAGATGATCAAATTTGATTTAGGACCGGAAGCAAT
GATTTTGGAGAGCCGAAAAGTTCGACAGCCCGGTATTCTCGGGTTTTTTAAACCGCCCGTTTTGGAGGTGTTGGCAGCGG
TTGATGAAGCGGCAAAACCCAGAAAAGACGTGGCTAAAGAAACTTTTGAAGTTAAAAAGGATTTGGCCGAATTAAAATTA
ATGGTTAAGGATTTAGCGCGGGTAACCGGGACCGAAACGGGTAATTTTGCCCGCTGGCAGGAACGCCTTTTAAAACTTGA
ACTGGCACCGGATATTGTGGAGCAGATTTTGCTGGAACTGCAGGATTTTTTGGAAGAAGTGGCGCCGGAGGAAACTTCCG
GAGTGGAGCGGGTAAAAGAGTATTTAATAAATTTAATTAAACCCTATTATGAAAACATCCAGGACTTTCCCTTAAAAGCA
TTAATTGGTCCGACCGGTGTGGGAAAAACAACAACCCTGGCCAAGATTGCCGGACGTTTGGCAATTCATGAAGAAAAACC
AATACGGTTCATTACCCTGGATACCTTTCGCGTGGGGGCAGTCGAGCAGCTCAAGATTTACGGCAAGTACCTCGGTACAA
CGGTTAAAGTTGCCGGCTCACCGATGGAGCTTTGGCGGGCGGTGCAAAAGCAAAATGAGGGAGAAACTATTTTTATTGAC
ACCGCTGGCCGGCCATCCAAAAAGCAAAACCAAATTCAGGAACTGGCCGGTTTTTTGGAAGCGGTTAAAAAGGAAAAAGA
CATTTATCTGGTGATAAGCGCTACCGTCAAACCCGAAGATGCGGAAAAAATCGCTAAAGACTTTTCCCCTTGCGGTTTTA
ATAAATTTATCGTAACCAAAATAGATGAAACCGATAAATTTGGAGTATTGATTAATTTAATCGTTAAATTTAAAAAGCCA
ATCGTTTACTTGGGCGTTGGGCAAAATGTTCCCGATGACTTAATATCTGCTACCCCGGAGCTTATCGTCGAGCAGGTGTG
GAAGGGGTGGTAG

Upstream 100 bases:

>100_bases
GACGGCTACTTGACCGTTTTTATCCGCAGGCGATTTTGCTGGGCATTAATGAAATTCCACCGGATGTTGAGGTAGAAATT
TTAGGGACGGTGAATTAGCG

Downstream 100 bases:

>100_bases
GAGATGTACCGGCAGGCGGTGGGATTAATTAAAGGTAATAAAGGTAATAAAGGGGAAGCAAAAGAAAATGCTACTCTGCA
GCGGATAATTGCGGTAACCA

Product: flagellar biosynthesis regulator FlhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKIKKYTARDMAEALQMIKFDLGPEAMILESRKVRQPGILGFFKPPVLEVLAAVDEAAKPRKDVAKETFEVKKDLAELKL
MVKDLARVTGTETGNFARWQERLLKLELAPDIVEQILLELQDFLEEVAPEETSGVERVKEYLINLIKPYYENIQDFPLKA
LIGPTGVGKTTTLAKIAGRLAIHEEKPIRFITLDTFRVGAVEQLKIYGKYLGTTVKVAGSPMELWRAVQKQNEGETIFID
TAGRPSKKQNQIQELAGFLEAVKKEKDIYLVISATVKPEDAEKIAKDFSPCGFNKFIVTKIDETDKFGVLINLIVKFKKP
IVYLGVGQNVPDDLISATPELIVEQVWKGW

Sequences:

>Translated_350_residues
MKIKKYTARDMAEALQMIKFDLGPEAMILESRKVRQPGILGFFKPPVLEVLAAVDEAAKPRKDVAKETFEVKKDLAELKL
MVKDLARVTGTETGNFARWQERLLKLELAPDIVEQILLELQDFLEEVAPEETSGVERVKEYLINLIKPYYENIQDFPLKA
LIGPTGVGKTTTLAKIAGRLAIHEEKPIRFITLDTFRVGAVEQLKIYGKYLGTTVKVAGSPMELWRAVQKQNEGETIFID
TAGRPSKKQNQIQELAGFLEAVKKEKDIYLVISATVKPEDAEKIAKDFSPCGFNKFIVTKIDETDKFGVLINLIVKFKKP
IVYLGVGQNVPDDLISATPELIVEQVWKGW
>Mature_350_residues
MKIKKYTARDMAEALQMIKFDLGPEAMILESRKVRQPGILGFFKPPVLEVLAAVDEAAKPRKDVAKETFEVKKDLAELKL
MVKDLARVTGTETGNFARWQERLLKLELAPDIVEQILLELQDFLEEVAPEETSGVERVKEYLINLIKPYYENIQDFPLKA
LIGPTGVGKTTTLAKIAGRLAIHEEKPIRFITLDTFRVGAVEQLKIYGKYLGTTVKVAGSPMELWRAVQKQNEGETIFID
TAGRPSKKQNQIQELAGFLEAVKKEKDIYLVISATVKPEDAEKIAKDFSPCGFNKFIVTKIDETDKFGVLINLIVKFKKP
IVYLGVGQNVPDDLISATPELIVEQVWKGW

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum [H]

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=186, Percent_Identity=30.1075268817204, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1789874, Length=184, Percent_Identity=33.1521739130435, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6325345, Length=186, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17647949, Length=210, Percent_Identity=29.0476190476191, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000897
- InterPro:   IPR020006 [H]

Pfam domain/function: PF00448 SRP54 [H]

EC number: NA

Molecular weight: Translated: 39391; Mature: 39391

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKKYTARDMAEALQMIKFDLGPEAMILESRKVRQPGILGFFKPPVLEVLAAVDEAAKP
CCCCHHHHHHHHHHHHHHHHCCCCCCEEECCHHCCCCCCCCCCCHHHHHHHHHHHHHCCC
RKDVAKETFEVKKDLAELKLMVKDLARVTGTETGNFARWQERLLKLELAPDIVEQILLEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
QDFLEEVAPEETSGVERVKEYLINLIKPYYENIQDFPLKALIGPTGVGKTTTLAKIAGRL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCHHCCCHHHHCCCCCCCCHHHHHHHHHHH
AIHEEKPIRFITLDTFRVGAVEQLKIYGKYLGTTVKVAGSPMELWRAVQKQNEGETIFID
HEECCCCEEEEEECCEECCHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHCCCCCEEEEE
TAGRPSKKQNQIQELAGFLEAVKKEKDIYLVISATVKPEDAEKIAKDFSPCGFNKFIVTK
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCEEEEE
IDETDKFGVLINLIVKFKKPIVYLGVGQNVPDDLISATPELIVEQVWKGW
CCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MKIKKYTARDMAEALQMIKFDLGPEAMILESRKVRQPGILGFFKPPVLEVLAAVDEAAKP
CCCCHHHHHHHHHHHHHHHHCCCCCCEEECCHHCCCCCCCCCCCHHHHHHHHHHHHHCCC
RKDVAKETFEVKKDLAELKLMVKDLARVTGTETGNFARWQERLLKLELAPDIVEQILLEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
QDFLEEVAPEETSGVERVKEYLINLIKPYYENIQDFPLKALIGPTGVGKTTTLAKIAGRL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCHHCCCHHHHCCCCCCCCHHHHHHHHHHH
AIHEEKPIRFITLDTFRVGAVEQLKIYGKYLGTTVKVAGSPMELWRAVQKQNEGETIFID
HEECCCCEEEEEECCEECCHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHCCCCCEEEEE
TAGRPSKKQNQIQELAGFLEAVKKEKDIYLVISATVKPEDAEKIAKDFSPCGFNKFIVTK
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCEEEEE
IDETDKFGVLINLIVKFKKPIVYLGVGQNVPDDLISATPELIVEQVWKGW
CCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1447978; 9384377 [H]