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The map label for this gene is yjcC [H]

Identifier: 77747706

GI number: 77747706

Start: 1870904

End: 1872472

Strand: Reverse

Name: yjcC [H]

Synonym: PD1617

Alternate gene names: 77747706

Gene position: 1872472-1870904 (Counterclockwise)

Preceding gene: 28199496

Following gene: 28199493

Centisome position: 74.31

GC content: 51.63

Gene sequence:

>1569_bases
TTGAAACGTTGTTGGACTCTTATCGTCGGTGCCACGCTTTGCATAGCGTGTCTTTCTGTTTCAATTGCATTGACTGATGG
CTACGTTTGGGTGACGACGCAGCGTCACGAACAACAGCGCCTGCGCGACTTGGCGCAGCAAATGGGTCAACGGGTGGATC
GCGCCGTTTCCGAATCATTGCTGCTCCTGTCAGACATGGATCATGCGCACTTGGCCCCGTGTTCTCCAGAACACATCGCA
CGGATGCGTGCATTGGTGCTGGCTACCCGCTACATCACAGAACTTGACTATGCCCCGACTCAGAAACTGAGCTGTACATC
GTGGGGGCCGTTTGATGGTGCATTCAAGCAGACGTTGACCAGCGATACCAGAAACGATGGCCTTGAATTGGTGAAGCGGG
TGTCTTTACCGCTGAACCCTGAGCAGCGCCTGCTGGGCTTGCATCATGGTGACTACCATGCACTGATGAAGCTCAGCACC
TTTATGGATTTTCCAATTCCACCCGGTGTGGAATTGGCACTGGCCACTATGGATGGGGTACTGTTGCTGAGCACTGGTTC
TCATGTGAAAGAACTGTTTAGTAACCCTGTGAATCAATCAGCGAGTGATCCTTCGCATGATGTGGTCGCAGCCCGCATTC
AAAACCCTCATCATGATTGGCAGATCGCTGTCATTGAACCAATCCAACAGCTTGTGGGTGCGGTACATCGCAAAGAGTGG
CTGGCCATCCCGGTTGCCTTATTGGTTTCATTGAGTGTCAGCGGCTTAGCCATCCTGTATTTGCGCCGGCGGCGCGCTCC
GTTGGCCCGGTTGCGTCAGGCCATCCAGCGATGTGAATTCTTTGTCTGCTATCAGCCGATTGTTTCACTGAGTGATGGGC
GTTGCGTCGGTGCAGAAGCATTGGTGCGTTGGCGCCAGCAAGACGGCACATTGATCTTGCCGGACCAATTCATTCCACTG
GCCGAGCGGAGTGGTTTAATTCTTCCCATTACCGATCAAGTCATCGCAGCGTCCATGCGTGAATTAGGACCATTACTGGT
GGCTGATCGTTCGTTGCACATTGCGATTAATGTTTCAGTGAAGGACATTGAATCAGGACGCTTACTGGATGTATTGGCGC
TTGCTTTACAAGACACTGGCCTATACAGAAAACAACTGTGGATCGAGGCGACTGAGCGCAGTTTCATGGATGCACGTGCC
GCACGCGAGCATATCGTGCGGCTACGAGAGGCTGGATATGCTGTAGTGATTGATGATTTTGGGACTGGTTATTCAAATTT
GCAGTATTTGCAGCAACTGCCATTAGACGCTTTGAAGATTGATAAATCCTTCATTGATACGGTTGGTCGCGATGTCACTA
ACACAGCGGTTGCTTCGCACATCATCGACATTGCTAAGGAATTGGGCATGCGTACCATTGCTGAAGGTGTGGAGCGTGAG
GAACAACTCGTCTATCTACGTGCCCGTGGTGTGGATATGGCTCAAGGCTGGTTGTTCTCATCTCCGTTAAGCGTCGCTGA
GTTCGTTGACTATCTTTCCCACAATCGCAGTATGCATCCCGATGACTGA

Upstream 100 bases:

>100_bases
ATTCCGTTGTTGTGATGCCAAGTAGAAAGAACATGGAAAATAGTGTTGATCAATATTTCGAGTCTTTGGACTCCCATTGT
TCTCATTTCGTGACTCCCGC

Downstream 100 bases:

>100_bases
GGTATTTTGTGCTTGTGGCATGGCTCCTTGGACGAGGTGTGCGACTTTTTGAAGTTGCTGTATGGATGGTACGGAGCAGC
GTTGGTGTGGTGGCGATAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MKRCWTLIVGATLCIACLSVSIALTDGYVWVTTQRHEQQRLRDLAQQMGQRVDRAVSESLLLLSDMDHAHLAPCSPEHIA
RMRALVLATRYITELDYAPTQKLSCTSWGPFDGAFKQTLTSDTRNDGLELVKRVSLPLNPEQRLLGLHHGDYHALMKLST
FMDFPIPPGVELALATMDGVLLLSTGSHVKELFSNPVNQSASDPSHDVVAARIQNPHHDWQIAVIEPIQQLVGAVHRKEW
LAIPVALLVSLSVSGLAILYLRRRRAPLARLRQAIQRCEFFVCYQPIVSLSDGRCVGAEALVRWRQQDGTLILPDQFIPL
AERSGLILPITDQVIAASMRELGPLLVADRSLHIAINVSVKDIESGRLLDVLALALQDTGLYRKQLWIEATERSFMDARA
AREHIVRLREAGYAVVIDDFGTGYSNLQYLQQLPLDALKIDKSFIDTVGRDVTNTAVASHIIDIAKELGMRTIAEGVERE
EQLVYLRARGVDMAQGWLFSSPLSVAEFVDYLSHNRSMHPDD

Sequences:

>Translated_522_residues
MKRCWTLIVGATLCIACLSVSIALTDGYVWVTTQRHEQQRLRDLAQQMGQRVDRAVSESLLLLSDMDHAHLAPCSPEHIA
RMRALVLATRYITELDYAPTQKLSCTSWGPFDGAFKQTLTSDTRNDGLELVKRVSLPLNPEQRLLGLHHGDYHALMKLST
FMDFPIPPGVELALATMDGVLLLSTGSHVKELFSNPVNQSASDPSHDVVAARIQNPHHDWQIAVIEPIQQLVGAVHRKEW
LAIPVALLVSLSVSGLAILYLRRRRAPLARLRQAIQRCEFFVCYQPIVSLSDGRCVGAEALVRWRQQDGTLILPDQFIPL
AERSGLILPITDQVIAASMRELGPLLVADRSLHIAINVSVKDIESGRLLDVLALALQDTGLYRKQLWIEATERSFMDARA
AREHIVRLREAGYAVVIDDFGTGYSNLQYLQQLPLDALKIDKSFIDTVGRDVTNTAVASHIIDIAKELGMRTIAEGVERE
EQLVYLRARGVDMAQGWLFSSPLSVAEFVDYLSHNRSMHPDD
>Mature_522_residues
MKRCWTLIVGATLCIACLSVSIALTDGYVWVTTQRHEQQRLRDLAQQMGQRVDRAVSESLLLLSDMDHAHLAPCSPEHIA
RMRALVLATRYITELDYAPTQKLSCTSWGPFDGAFKQTLTSDTRNDGLELVKRVSLPLNPEQRLLGLHHGDYHALMKLST
FMDFPIPPGVELALATMDGVLLLSTGSHVKELFSNPVNQSASDPSHDVVAARIQNPHHDWQIAVIEPIQQLVGAVHRKEW
LAIPVALLVSLSVSGLAILYLRRRRAPLARLRQAIQRCEFFVCYQPIVSLSDGRCVGAEALVRWRQQDGTLILPDQFIPL
AERSGLILPITDQVIAASMRELGPLLVADRSLHIAINVSVKDIESGRLLDVLALALQDTGLYRKQLWIEATERSFMDARA
AREHIVRLREAGYAVVIDDFGTGYSNLQYLQQLPLDALKIDKSFIDTVGRDVTNTAVASHIIDIAKELGMRTIAEGVERE
EQLVYLRARGVDMAQGWLFSSPLSVAEFVDYLSHNRSMHPDD

Specific function: Overexpression reduces biofilm formation [H]

COG id: COG4943

COG function: function code T; Predicted signal transduction protein containing sensor and EAL domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=519, Percent_Identity=28.9017341040462, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI87081743, Length=516, Percent_Identity=29.0697674418605, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI87081845, Length=266, Percent_Identity=35.7142857142857, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1788502, Length=267, Percent_Identity=35.2059925093633, Blast_Score=156, Evalue=4e-39,
Organism=Escherichia coli, GI87081980, Length=244, Percent_Identity=36.0655737704918, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI1786507, Length=240, Percent_Identity=36.25, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI87081921, Length=249, Percent_Identity=34.5381526104418, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1787541, Length=239, Percent_Identity=31.3807531380753, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI226510982, Length=243, Percent_Identity=36.2139917695473, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787055, Length=244, Percent_Identity=33.6065573770492, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788849, Length=243, Percent_Identity=30.4526748971193, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87082096, Length=241, Percent_Identity=25.3112033195021, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 58249; Mature: 58249

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRCWTLIVGATLCIACLSVSIALTDGYVWVTTQRHEQQRLRDLAQQMGQRVDRAVSESL
CCHHHHHHHHHHHHHHHHHHHEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLSDMDHAHLAPCSPEHIARMRALVLATRYITELDYAPTQKLSCTSWGPFDGAFKQTLT
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
SDTRNDGLELVKRVSLPLNPEQRLLGLHHGDYHALMKLSTFMDFPIPPGVELALATMDGV
CCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCE
LLLSTGSHVKELFSNPVNQSASDPSHDVVAARIQNPHHDWQIAVIEPIQQLVGAVHRKEW
EEEECCHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHH
LAIPVALLVSLSVSGLAILYLRRRRAPLARLRQAIQRCEFFVCYQPIVSLSDGRCVGAEA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEHHHHCCCCCCEECHHH
LVRWRQQDGTLILPDQFIPLAERSGLILPITDQVIAASMRELGPLLVADRSLHIAINVSV
HHHHHHCCCCEECCCCCCCHHCCCCEEEEEHHHHHHHHHHHCCCEEEECCEEEEEEEEEE
KDIESGRLLDVLALALQDTGLYRKQLWIEATERSFMDARAAREHIVRLREAGYAVVIDDF
EECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
GTGYSNLQYLQQLPLDALKIDKSFIDTVGRDVTNTAVASHIIDIAKELGMRTIAEGVERE
CCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCHH
EQLVYLRARGVDMAQGWLFSSPLSVAEFVDYLSHNRSMHPDD
HHEEEEEECCCCHHCCCCCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKRCWTLIVGATLCIACLSVSIALTDGYVWVTTQRHEQQRLRDLAQQMGQRVDRAVSESL
CCHHHHHHHHHHHHHHHHHHHEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLSDMDHAHLAPCSPEHIARMRALVLATRYITELDYAPTQKLSCTSWGPFDGAFKQTLT
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
SDTRNDGLELVKRVSLPLNPEQRLLGLHHGDYHALMKLSTFMDFPIPPGVELALATMDGV
CCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCE
LLLSTGSHVKELFSNPVNQSASDPSHDVVAARIQNPHHDWQIAVIEPIQQLVGAVHRKEW
EEEECCHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHH
LAIPVALLVSLSVSGLAILYLRRRRAPLARLRQAIQRCEFFVCYQPIVSLSDGRCVGAEA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEHHHHCCCCCCEECHHH
LVRWRQQDGTLILPDQFIPLAERSGLILPITDQVIAASMRELGPLLVADRSLHIAINVSV
HHHHHHCCCCEECCCCCCCHHCCCCEEEEEHHHHHHHHHHHCCCEEEECCEEEEEEEEEE
KDIESGRLLDVLALALQDTGLYRKQLWIEATERSFMDARAAREHIVRLREAGYAVVIDDF
EECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
GTGYSNLQYLQQLPLDALKIDKSFIDTVGRDVTNTAVASHIIDIAKELGMRTIAEGVERE
CCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCHH
EQLVYLRARGVDMAQGWLFSSPLSVAEFVDYLSHNRSMHPDD
HHEEEEEECCCCHHCCCCCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]