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The map label for this gene is qor [H]

Identifier: 77465383

GI number: 77465383

Start: 444827

End: 445801

Strand: Reverse

Name: qor [H]

Synonym: RSP_3381

Alternate gene names: 77465383

Gene position: 445801-444827 (Counterclockwise)

Preceding gene: 77465384

Following gene: 77465378

Centisome position: 47.27

GC content: 72.1

Gene sequence:

>975_bases
ATGACCGATCACGCCATCGTTGCGACCCGCCCCGGCGGCCCCGACGTGCTCGAATGGGCCGAGCGCCCCGCCGGGCGGCC
CGGACCGGGCGAGGTGCGCCTGCGCCAGACGGCCGTCGGGCTGAACTTCATCGACTGCTACTTCCGCTCGGGCCTCTATC
CCTGGCCCGCCGATGAGCTGATCCCCGGCGGCGAGGCCGCAGGCGTGGTCGAGGAGCTGGGCGAAGGCGTGAGCGGCTTC
GCGCCCGGCGACAGGGTGGCCTATACGATGCCGAACGGCGCCTGCCGCACGGCTCGGGTCCTGCCCGCCGACCGGCTGGT
CCGGCTGCCCGAGGGCGTGACGGACGAGGTGGCGGCCTCGATCATGCTGAAGGGGCTGACGGCGCAGTACCTGATCCATT
CGAGTTTCCGGGTGGAGGCGGGGCACCATGTCCTCGTCCATGCCGCAGCGGGCGGCGTGGGACAGCTTCTCGGCCAGTGG
CTGAAGGCCAAGGGCGCCATCACCTACGGAACGGTCGGCGGCGCGGCCAAGGCCGAGATGGCGCGCGCCAGCGGCTTCGA
CCATGTGATCGATTACGAGGCCACCGACTTCGCCGAGGCGGTGCGCGAGCTGACCGGCGGGCGCGGCTGCGATGTCGTCT
ATGACTCGGTCGGCCGCACCACCTGGCGCGGGTCGCTGAAGAGCCTGCGGCCGCGCGGCAGCTTCGTCTGTTTCGGCCAG
TCCTCGGGCCCGCTCGACGAGTTCCGCTTCTCCGACCTCGCGGCGGGCAGCTTCACCGCGAACCGGCCCTCGCTCTTCCA
TTACATTGCCACGCGCGACGAGCTCGAGGCGCGGGCGGCCGATCTCTTTGCGCTGGTGGCCGAGGGGCGGATCGTGCCGC
GGATCGGGCAGACCTTCGCGCTGAAGGACACGGCCGAGGCGCACCGCGCGCTGGAGGGTCGCCGCACCACCGGGGCGACC
GTGCTTCTGCCCTGA

Upstream 100 bases:

>100_bases
AGGAGGCCGAGTTCCTCGCGGTGCTGGGCATGGCGGCCCAGACCAACCAGCTCGTGACCGCGCTTCAGGTGCCGGTCGAC
GCGGCCTTTCAGGTGGAAAC

Downstream 100 bases:

>100_bases
AAAAGCCGGGCGGAAGGGTCCGCCCGGCGTCACAGGTTGCCTGGTCGCCCCTGCCGCGGATCTCCGGCGGCAAGGGCCTG
CGGTCAGCGGACGATCTGCA

Product: NAD(P)H -dependent quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTDHAIVATRPGGPDVLEWAERPAGRPGPGEVRLRQTAVGLNFIDCYFRSGLYPWPADELIPGGEAAGVVEELGEGVSGF
APGDRVAYTMPNGACRTARVLPADRLVRLPEGVTDEVAASIMLKGLTAQYLIHSSFRVEAGHHVLVHAAAGGVGQLLGQW
LKAKGAITYGTVGGAAKAEMARASGFDHVIDYEATDFAEAVRELTGGRGCDVVYDSVGRTTWRGSLKSLRPRGSFVCFGQ
SSGPLDEFRFSDLAAGSFTANRPSLFHYIATRDELEARAADLFALVAEGRIVPRIGQTFALKDTAEAHRALEGRRTTGAT
VLLP

Sequences:

>Translated_324_residues
MTDHAIVATRPGGPDVLEWAERPAGRPGPGEVRLRQTAVGLNFIDCYFRSGLYPWPADELIPGGEAAGVVEELGEGVSGF
APGDRVAYTMPNGACRTARVLPADRLVRLPEGVTDEVAASIMLKGLTAQYLIHSSFRVEAGHHVLVHAAAGGVGQLLGQW
LKAKGAITYGTVGGAAKAEMARASGFDHVIDYEATDFAEAVRELTGGRGCDVVYDSVGRTTWRGSLKSLRPRGSFVCFGQ
SSGPLDEFRFSDLAAGSFTANRPSLFHYIATRDELEARAADLFALVAEGRIVPRIGQTFALKDTAEAHRALEGRRTTGAT
VLLP
>Mature_323_residues
TDHAIVATRPGGPDVLEWAERPAGRPGPGEVRLRQTAVGLNFIDCYFRSGLYPWPADELIPGGEAAGVVEELGEGVSGFA
PGDRVAYTMPNGACRTARVLPADRLVRLPEGVTDEVAASIMLKGLTAQYLIHSSFRVEAGHHVLVHAAAGGVGQLLGQWL
KAKGAITYGTVGGAAKAEMARASGFDHVIDYEATDFAEAVRELTGGRGCDVVYDSVGRTTWRGSLKSLRPRGSFVCFGQS
SGPLDEFRFSDLAAGSFTANRPSLFHYIATRDELEARAADLFALVAEGRIVPRIGQTFALKDTAEAHRALEGRRTTGATV
LLP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=31.8327974276527, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI22538446, Length=322, Percent_Identity=31.3664596273292, Blast_Score=134, Evalue=9e-32,
Organism=Homo sapiens, GI22538444, Length=322, Percent_Identity=31.3664596273292, Blast_Score=134, Evalue=9e-32,
Organism=Homo sapiens, GI194239674, Length=319, Percent_Identity=31.6614420062696, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI13236495, Length=319, Percent_Identity=31.6614420062696, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI24308257, Length=348, Percent_Identity=26.4367816091954, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI194239676, Length=319, Percent_Identity=30.0940438871473, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI28557745, Length=284, Percent_Identity=26.7605633802817, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI197927207, Length=191, Percent_Identity=29.3193717277487, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI41872631, Length=249, Percent_Identity=30.9236947791165, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1790485, Length=319, Percent_Identity=43.2601880877743, Blast_Score=241, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI17507255, Length=312, Percent_Identity=27.5641025641026, Blast_Score=100, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6319520, Length=322, Percent_Identity=33.5403726708075, Blast_Score=193, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6324486, Length=282, Percent_Identity=27.3049645390071, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=252, Percent_Identity=25.3968253968254, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319621, Length=282, Percent_Identity=25.886524822695, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34464; Mature: 34333

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01162 QOR_ZETA_CRYSTAL ; PS00211 ABC_TRANSPORTER_1 ; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDHAIVATRPGGPDVLEWAERPAGRPGPGEVRLRQTAVGLNFIDCYFRSGLYPWPADEL
CCCCEEEEECCCCCHHHHHHHCCCCCCCCCCEEEEEHHHCCHHHHHHHHCCCCCCCHHHC
IPGGEAAGVVEELGEGVSGFAPGDRVAYTMPNGACRTARVLPADRLVRLPEGVTDEVAAS
CCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCEEECCHHHHEECCCCCHHHHHHH
IMLKGLTAQYLIHSSFRVEAGHHVLVHAAAGGVGQLLGQWLKAKGAITYGTVGGAAKAEM
HHHHHHHHHHHHHCCEEEECCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCHHHHHH
ARASGFDHVIDYEATDFAEAVRELTGGRGCDVVYDSVGRTTWRGSLKSLRPRGSFVCFGQ
HHHCCCCCEECCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHCHHHHCCCCCCEEEECC
SSGPLDEFRFSDLAAGSFTANRPSLFHYIATRDELEARAADLFALVAEGRIVPRIGQTFA
CCCCHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCEECCCCCEEE
LKDTAEAHRALEGRRTTGATVLLP
ECCHHHHHHHHCCCCCCCCEEEEC
>Mature Secondary Structure 
TDHAIVATRPGGPDVLEWAERPAGRPGPGEVRLRQTAVGLNFIDCYFRSGLYPWPADEL
CCCEEEEECCCCCHHHHHHHCCCCCCCCCCEEEEEHHHCCHHHHHHHHCCCCCCCHHHC
IPGGEAAGVVEELGEGVSGFAPGDRVAYTMPNGACRTARVLPADRLVRLPEGVTDEVAAS
CCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCEEECCHHHHEECCCCCHHHHHHH
IMLKGLTAQYLIHSSFRVEAGHHVLVHAAAGGVGQLLGQWLKAKGAITYGTVGGAAKAEM
HHHHHHHHHHHHHCCEEEECCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCHHHHHH
ARASGFDHVIDYEATDFAEAVRELTGGRGCDVVYDSVGRTTWRGSLKSLRPRGSFVCFGQ
HHHCCCCCEECCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHCHHHHCCCCCCEEEECC
SSGPLDEFRFSDLAAGSFTANRPSLFHYIATRDELEARAADLFALVAEGRIVPRIGQTFA
CCCCHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCEECCCCCEEE
LKDTAEAHRALEGRRTTGATVLLP
ECCHHHHHHHHCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]