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The map label for this gene is ggt [H]

Identifier: 77465278

GI number: 77465278

Start: 330105

End: 331892

Strand: Reverse

Name: ggt [H]

Synonym: RSP_3272

Alternate gene names: 77465278

Gene position: 331892-330105 (Counterclockwise)

Preceding gene: 77465279

Following gene: 77465271

Centisome position: 35.19

GC content: 72.15

Gene sequence:

>1788_bases
ATGCCCATGGTCCGCACGCTCGCCCTGTTCCTCGCCTCGGCCCTGCCCGCCTTCGCGCAACAGGCCAGCGACACGCTGGC
CCCCGAGGCGCCCACCGCGCCCGCGGCCTTCGGCAGCCTCTCGCCCGCAGCCGCCGCGGCGATGGAGACGCGCGACTCGG
GACGGCCCGTCGAGGCGGAGGACTGGATGGTGGTGGCTGCGAACCCGCTCGCCGTCGAGGCCGGAGCCGAGATCCTGCGC
AGCGGCGGCAGCGCGGCCGATGCCATGGTCGCCGTCCAGACCGTGCTGGGGCTGGTCGAGCCGCAATCCTCGGGGCTCGG
CGGCGGCGCCTTCCTCGTCTGGTTCGATGCGGCGACCGGCGCCGTCACCACGCTCGATGCGCGCGAGACCGCGCCGCGGG
CCGCGACCCCCCGGCTCTTCCAGACGCCCGAGGGCGAGCCGCTGGAATTCCTCGACGCGGTGGTGGGCGGCCGGTCCGTG
GGCACCCCCGGCACGCCGCTTCTGCTCGAGGAGGCGCACCGGCGCTGGGGCAGGTCCGGCTGGTCCGACCTCTTCGATCC
GGCCATCCGTCTGGCCGAGGAGGGCTTTGCGGTCTCGCCGCGTCTCGCGGGGCTCGTGGCCGAGGATCCCGAGGGGCTCT
CGCGCTTTCCCGCCACCGCCGCCTATTTCCTGCCCGAGGGCCAGCCGCTGAAGGCCGGAGCCCTCCTGAAGAACCCCGAC
TATGCCGAGACCCTTCGCCGTCTGGCGGCCGAAGGCGCGGATGCGTTCTACCGCGGCCCCATCGCCGAGGAGATCGTGGC
CACCGTCCGCGGCGCCGAGGGCAATCCGGGCGTGCTCGCGCTCGAGGATCTGGCCGCCTACCGCGTGGTGGAGCGTCCGC
CCGTCTGCGCCGACTACCGCGGCGCCGAGATCTGCGGCATGGGTCCGCCCTCGTCGGGAGCGCTGACCGTGGGGCTGATC
CTCGGCGCGCTCGAGCCCTACGATCTGGCCGCCCTCGGGCCCGAGAATGCCGAAAGCTGGCGCCTGATCGGCGATGCGAC
CCGCCTCGCCTTCGCCGACCGCGGCCGATACATGGCCGACAGAGATTTCGTGCCGGTGCCCGTCGAGGGGCTGCTCGATC
CCGCCTATCTCGCCGCCCGGGCCGAGCTTCTGCGCGGAGACGATGCGTTGCCCGAGGTGGCGGCCGGCACGCCCGAATGG
GATCACGCGGGGCTCCTCGCCCCCGACGAGAGCCTCGAATTGCCCTCGACCTCGCATATCTCCATCGTGGATGCGGCGGG
CAACGTGCTCTCGATGACGACGACCATCGAGAACGGCTTCGGCTCGCGGCTGATGACGAACGGGTTCCTCCTGAACAACG
AACTCACCGACTTCTCCTTCCGCACCCATGCGGAGGGCTGGCCCATCGCGAACCGGGTGGAGCCCGGCAAGCGCCCGCGC
TCGTCGATGGCGCCCACCATCGTACTCCGCGACGGCAAGCCCGTGCTGGCGGTGGGCAGCCCCGGCGGCTCCACGATCAT
CGGCTATGTGGCACAGGCGCTGATCGCCCATCTCGACTGGGGCATGGATGTGCAGCAGGCGGTGGCCATGCCGCATCTCG
TGAACACTTTCGGCCCGTTCCAGATCGAGGCCGGCACCCGCGCCGAAGCGCTGAGCCAGCCGCTCGCCGATCTGGGTTAT
GACGTGAAGCCGGTGGACCTGACCTCCGGCCTCCATGCGATCTCGCTGGGCGAGAGGTTGCAGGGCGGCGCCGATCCCCG
CCGCGAGGGAATCGCGCTGGGCGAGTGA

Upstream 100 bases:

>100_bases
TCCGCTCGGGCTGGCGCATCCGGCCCTGAGCGCGGGACAGGCGTCGGTTGCGCTTGACCCGGCCTCTGCACGGGCCAGTT
GATAGGGTCTAGGAAAGGAG

Downstream 100 bases:

>100_bases
CCCGCCCGCCCGCGAAACGTGATCCTGCAAAAGCCGAGGCCGGGCGGATGCCGCCCGGCCCTTCGTCAAAAGCCCTCAGG
CCGCGCGATGCAGCCGGTCG

Product: gamma-glutamyltransferase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 595; Mature: 594

Protein sequence:

>595_residues
MPMVRTLALFLASALPAFAQQASDTLAPEAPTAPAAFGSLSPAAAAAMETRDSGRPVEAEDWMVVAANPLAVEAGAEILR
SGGSAADAMVAVQTVLGLVEPQSSGLGGGAFLVWFDAATGAVTTLDARETAPRAATPRLFQTPEGEPLEFLDAVVGGRSV
GTPGTPLLLEEAHRRWGRSGWSDLFDPAIRLAEEGFAVSPRLAGLVAEDPEGLSRFPATAAYFLPEGQPLKAGALLKNPD
YAETLRRLAAEGADAFYRGPIAEEIVATVRGAEGNPGVLALEDLAAYRVVERPPVCADYRGAEICGMGPPSSGALTVGLI
LGALEPYDLAALGPENAESWRLIGDATRLAFADRGRYMADRDFVPVPVEGLLDPAYLAARAELLRGDDALPEVAAGTPEW
DHAGLLAPDESLELPSTSHISIVDAAGNVLSMTTTIENGFGSRLMTNGFLLNNELTDFSFRTHAEGWPIANRVEPGKRPR
SSMAPTIVLRDGKPVLAVGSPGGSTIIGYVAQALIAHLDWGMDVQQAVAMPHLVNTFGPFQIEAGTRAEALSQPLADLGY
DVKPVDLTSGLHAISLGERLQGGADPRREGIALGE

Sequences:

>Translated_595_residues
MPMVRTLALFLASALPAFAQQASDTLAPEAPTAPAAFGSLSPAAAAAMETRDSGRPVEAEDWMVVAANPLAVEAGAEILR
SGGSAADAMVAVQTVLGLVEPQSSGLGGGAFLVWFDAATGAVTTLDARETAPRAATPRLFQTPEGEPLEFLDAVVGGRSV
GTPGTPLLLEEAHRRWGRSGWSDLFDPAIRLAEEGFAVSPRLAGLVAEDPEGLSRFPATAAYFLPEGQPLKAGALLKNPD
YAETLRRLAAEGADAFYRGPIAEEIVATVRGAEGNPGVLALEDLAAYRVVERPPVCADYRGAEICGMGPPSSGALTVGLI
LGALEPYDLAALGPENAESWRLIGDATRLAFADRGRYMADRDFVPVPVEGLLDPAYLAARAELLRGDDALPEVAAGTPEW
DHAGLLAPDESLELPSTSHISIVDAAGNVLSMTTTIENGFGSRLMTNGFLLNNELTDFSFRTHAEGWPIANRVEPGKRPR
SSMAPTIVLRDGKPVLAVGSPGGSTIIGYVAQALIAHLDWGMDVQQAVAMPHLVNTFGPFQIEAGTRAEALSQPLADLGY
DVKPVDLTSGLHAISLGERLQGGADPRREGIALGE
>Mature_594_residues
PMVRTLALFLASALPAFAQQASDTLAPEAPTAPAAFGSLSPAAAAAMETRDSGRPVEAEDWMVVAANPLAVEAGAEILRS
GGSAADAMVAVQTVLGLVEPQSSGLGGGAFLVWFDAATGAVTTLDARETAPRAATPRLFQTPEGEPLEFLDAVVGGRSVG
TPGTPLLLEEAHRRWGRSGWSDLFDPAIRLAEEGFAVSPRLAGLVAEDPEGLSRFPATAAYFLPEGQPLKAGALLKNPDY
AETLRRLAAEGADAFYRGPIAEEIVATVRGAEGNPGVLALEDLAAYRVVERPPVCADYRGAEICGMGPPSSGALTVGLIL
GALEPYDLAALGPENAESWRLIGDATRLAFADRGRYMADRDFVPVPVEGLLDPAYLAARAELLRGDDALPEVAAGTPEWD
HAGLLAPDESLELPSTSHISIVDAAGNVLSMTTTIENGFGSRLMTNGFLLNNELTDFSFRTHAEGWPIANRVEPGKRPRS
SMAPTIVLRDGKPVLAVGSPGGSTIIGYVAQALIAHLDWGMDVQQAVAMPHLVNTFGPFQIEAGTRAEALSQPLADLGYD
VKPVDLTSGLHAISLGERLQGGADPRREGIALGE

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=482, Percent_Identity=34.0248962655602, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI73915090, Length=482, Percent_Identity=34.0248962655602, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI73915096, Length=482, Percent_Identity=34.0248962655602, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI73915094, Length=482, Percent_Identity=34.0248962655602, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI113429324, Length=483, Percent_Identity=33.1262939958592, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI113429326, Length=488, Percent_Identity=32.5819672131148, Blast_Score=196, Evalue=8e-50,
Organism=Homo sapiens, GI109148539, Length=546, Percent_Identity=31.5018315018315, Blast_Score=153, Evalue=5e-37,
Organism=Homo sapiens, GI153266885, Length=535, Percent_Identity=28.9719626168224, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI153266901, Length=536, Percent_Identity=28.9179104477612, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI153266907, Length=534, Percent_Identity=26.9662921348315, Blast_Score=123, Evalue=6e-28,
Organism=Homo sapiens, GI30581157, Length=171, Percent_Identity=35.0877192982456, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI30581155, Length=171, Percent_Identity=35.0877192982456, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI218505805, Length=131, Percent_Identity=38.9312977099237, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789856, Length=552, Percent_Identity=36.0507246376812, Blast_Score=303, Evalue=3e-83,
Organism=Caenorhabditis elegans, GI72000294, Length=505, Percent_Identity=31.6831683168317, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI212646519, Length=505, Percent_Identity=31.6831683168317, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17542894, Length=551, Percent_Identity=30.3085299455535, Blast_Score=195, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI193208247, Length=564, Percent_Identity=29.6099290780142, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI193208245, Length=565, Percent_Identity=29.5575221238938, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17506189, Length=552, Percent_Identity=29.7101449275362, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17564448, Length=429, Percent_Identity=24.9417249417249, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI72001497, Length=411, Percent_Identity=24.5742092457421, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI72001495, Length=387, Percent_Identity=24.2894056847545, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323330, Length=525, Percent_Identity=28.3809523809524, Blast_Score=140, Evalue=8e-34,
Organism=Drosophila melanogaster, GI161077496, Length=499, Percent_Identity=31.062124248497, Blast_Score=187, Evalue=3e-47,
Organism=Drosophila melanogaster, GI18859893, Length=556, Percent_Identity=30.9352517985612, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24642670, Length=546, Percent_Identity=27.6556776556777, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24642666, Length=546, Percent_Identity=27.6556776556777, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI45551474, Length=546, Percent_Identity=27.6556776556777, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI161077880, Length=546, Percent_Identity=27.6556776556777, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI161077878, Length=546, Percent_Identity=27.6556776556777, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI18859741, Length=474, Percent_Identity=26.5822784810127, Blast_Score=113, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 62168; Mature: 62037

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMVRTLALFLASALPAFAQQASDTLAPEAPTAPAAFGSLSPAAAAAMETRDSGRPVEAE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
DWMVVAANPLAVEAGAEILRSGGSAADAMVAVQTVLGLVEPQSSGLGGGAFLVWFDAATG
CEEEEECCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCC
AVTTLDARETAPRAATPRLFQTPEGEPLEFLDAVVGGRSVGTPGTPLLLEEAHRRWGRSG
CEEEECCHHCCCCCCCCCCEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
WSDLFDPAIRLAEEGFAVSPRLAGLVAEDPEGLSRFPATAAYFLPEGQPLKAGALLKNPD
HHHHHHHHHHHHHCCCEECCHHHCEECCCCHHHHHCCCCEEEECCCCCCCCCCCEECCCC
YAETLRRLAAEGADAFYRGPIAEEIVATVRGAEGNPGVLALEDLAAYRVVERPPVCADYR
HHHHHHHHHHCCCCHHHCCCHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCC
GAEICGMGPPSSGALTVGLILGALEPYDLAALGPENAESWRLIGDATRLAFADRGRYMAD
CCEEECCCCCCCCCEEHHHHHHCCCCCCEEECCCCCCCCEEEEHHHHHHHHHHCCCEECC
RDFVPVPVEGLLDPAYLAARAELLRGDDALPEVAAGTPEWDHAGLLAPDESLELPSTSHI
CCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCE
SIVDAAGNVLSMTTTIENGFGSRLMTNGFLLNNELTDFSFRTHAEGWPIANRVEPGKRPR
EEEECCCCEEEEEEECCCCCCCHHHHCCEEECCCCCCCEEEECCCCCCCCCCCCCCCCCC
SSMAPTIVLRDGKPVLAVGSPGGSTIIGYVAQALIAHLDWGMDVQQAVAMPHLVNTFGPF
CCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCE
QIEAGTRAEALSQPLADLGYDVKPVDLTSGLHAISLGERLQGGADPRREGIALGE
EECCCCHHHHHHCCHHHCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHCCCCCCC
>Mature Secondary Structure 
PMVRTLALFLASALPAFAQQASDTLAPEAPTAPAAFGSLSPAAAAAMETRDSGRPVEAE
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
DWMVVAANPLAVEAGAEILRSGGSAADAMVAVQTVLGLVEPQSSGLGGGAFLVWFDAATG
CEEEEECCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCC
AVTTLDARETAPRAATPRLFQTPEGEPLEFLDAVVGGRSVGTPGTPLLLEEAHRRWGRSG
CEEEECCHHCCCCCCCCCCEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
WSDLFDPAIRLAEEGFAVSPRLAGLVAEDPEGLSRFPATAAYFLPEGQPLKAGALLKNPD
HHHHHHHHHHHHHCCCEECCHHHCEECCCCHHHHHCCCCEEEECCCCCCCCCCCEECCCC
YAETLRRLAAEGADAFYRGPIAEEIVATVRGAEGNPGVLALEDLAAYRVVERPPVCADYR
HHHHHHHHHHCCCCHHHCCCHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCC
GAEICGMGPPSSGALTVGLILGALEPYDLAALGPENAESWRLIGDATRLAFADRGRYMAD
CCEEECCCCCCCCCEEHHHHHHCCCCCCEEECCCCCCCCEEEEHHHHHHHHHHCCCEECC
RDFVPVPVEGLLDPAYLAARAELLRGDDALPEVAAGTPEWDHAGLLAPDESLELPSTSHI
CCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCE
SIVDAAGNVLSMTTTIENGFGSRLMTNGFLLNNELTDFSFRTHAEGWPIANRVEPGKRPR
EEEECCCCEEEEEEECCCCCCCHHHHCCEEECCCCCCCEEEECCCCCCCCCCCCCCCCCC
SSMAPTIVLRDGKPVLAVGSPGGSTIIGYVAQALIAHLDWGMDVQQAVAMPHLVNTFGPF
CCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCE
QIEAGTRAEALSQPLADLGYDVKPVDLTSGLHAISLGERLQGGADPRREGIALGE
EECCCCHHHHHHCCHHHCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA