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The map label for this gene is 77461920

Identifier: 77461920

GI number: 77461920

Start: 6389822

End: 6391138

Strand: Reverse

Name: 77461920

Synonym: Pfl01_5700

Alternate gene names: NA

Gene position: 6391138-6389822 (Counterclockwise)

Preceding gene: 77461922

Following gene: 77461919

Centisome position: 99.27

GC content: 48.82

Gene sequence:

>1317_bases
ATGTCGATACGTCATGCCTCGCCGCTAAACAGCATTGCGGTTGCCGTACTGCTAAGTGCAGGAACTTTGATGTCGGTGTC
GCCGTTTGCGCACGCGCAAAACGGTGCGACCGCTACAGTAGGCGCTGTAGTAGGCGACACAGCAATTCGGCCATTCAAAG
TCGAGATTCCGGAAGATGCGATAATTGATCTTAAGAAACGCGTCCTGGCCACTCGCTGGCCAGATCCGGAAACCGTAAAA
GATCAGTCACAAGGCGTCCAACAAGATAAGCTAAAGGCTTTGGTTGATTATTGGGGTAAAGATTACGACTGGCATAAAGT
CCAAAACAAGCTAAACGCACTTCCCATGTATATCACGCGGATTGACGGAGTGGATATCCAGTTCATCCATGTCAAATCTA
AACATCCTAACGCTTTACCGTTGCTATTGACCCATGGGTGGCCAGGTTCGATCCTGGAATTCACCAAATCGATCGCACCT
CTTACAGATCCGACTTCCTACGGTGGGCGTGCAGAAGATGCCTTTGATGTAATAATTCCTTCAATGCCAGGATATGGCTT
TTCACAACGCCCTACTGAGGGTGGTTGGGGGCCAGAGCGGATGGGGGCGGCATGGGATGTGCTGATGAAGCGTTTGGGTT
ATAAAAACTATGTTTCTCAGGGAGGGGATTGGGGCTCTGTAGTGGCGGATGCAATGGGACGCCAAGCTCCTTCGGGGTTG
CGAGCAATCCATGTAAATATGCCAGCCACCGTTCCACCTGAGATCGCGCGGGCAATCAATGACGGGACACCTCCTCCTGC
AGGAATCACTCCGGAAGAAAAGGCAGCTTACCAGTCCCTAAAAGATTTCTTCGGTAAGAATGCTGCTTACGGTTCTATGA
TGAGCACACGCCCGCAAACAGTTGGATATGCATTGAGCGACTCCCCTGCAGGGCTCGCCGCCTGGATCTTTGATAAATTT
AATCAGTGGACTTACAGCGGCGGCGATGCGGAAAAGTCATTGAGTAAGGACGAGATGCTGGACGATATCTCTCTGTATTG
GCTTACTAATAGTGCTGTTTCATCTGCACGTCTATACTGGGAAAACAATAATAATAATTTCAATTCTGTCGAGCAAAAAA
CACGCGAAATTAAGGTTCCAGTAGCGGTTACTGTTTTTCCGGGTGAAATCTATCAGGCACCGAAGACCTGGGCTGAACGA
GCTTACCCAACGCTAAAATATTACAATGTTGTTAATAAAGGCGGGCATTTTGCAGCCTGGGAAGAGCCAGAGCTTTTTGC
TTCTGAGCTGCGTAAAGCTTTCAAACCATATAGATAA

Upstream 100 bases:

>100_bases
GTGCAAGCTGATACCTTGGTGTAATACCTAAGGTGAAACAGGGAAGTAGACTTCAAGGGCAACTCAAACCACAGAAAAGA
AACAAAAAAGGATAATCGTT

Downstream 100 bases:

>100_bases
TTATAGCTAGTTGATTCATGCCTTTTGTATAATTTTTCGTTTGCTTTGACGATTGATCTATCATGAGGCATGACTCTATT
GTTTAATTATCGCCGTATAA

Product: epoxide hydrolase-like protein

Products: NA

Alternate protein names: Epoxide hydratase [H]

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MSIRHASPLNSIAVAVLLSAGTLMSVSPFAHAQNGATATVGAVVGDTAIRPFKVEIPEDAIIDLKKRVLATRWPDPETVK
DQSQGVQQDKLKALVDYWGKDYDWHKVQNKLNALPMYITRIDGVDIQFIHVKSKHPNALPLLLTHGWPGSILEFTKSIAP
LTDPTSYGGRAEDAFDVIIPSMPGYGFSQRPTEGGWGPERMGAAWDVLMKRLGYKNYVSQGGDWGSVVADAMGRQAPSGL
RAIHVNMPATVPPEIARAINDGTPPPAGITPEEKAAYQSLKDFFGKNAAYGSMMSTRPQTVGYALSDSPAGLAAWIFDKF
NQWTYSGGDAEKSLSKDEMLDDISLYWLTNSAVSSARLYWENNNNNFNSVEQKTREIKVPVAVTVFPGEIYQAPKTWAER
AYPTLKYYNVVNKGGHFAAWEEPELFASELRKAFKPYR

Sequences:

>Translated_438_residues
MSIRHASPLNSIAVAVLLSAGTLMSVSPFAHAQNGATATVGAVVGDTAIRPFKVEIPEDAIIDLKKRVLATRWPDPETVK
DQSQGVQQDKLKALVDYWGKDYDWHKVQNKLNALPMYITRIDGVDIQFIHVKSKHPNALPLLLTHGWPGSILEFTKSIAP
LTDPTSYGGRAEDAFDVIIPSMPGYGFSQRPTEGGWGPERMGAAWDVLMKRLGYKNYVSQGGDWGSVVADAMGRQAPSGL
RAIHVNMPATVPPEIARAINDGTPPPAGITPEEKAAYQSLKDFFGKNAAYGSMMSTRPQTVGYALSDSPAGLAAWIFDKF
NQWTYSGGDAEKSLSKDEMLDDISLYWLTNSAVSSARLYWENNNNNFNSVEQKTREIKVPVAVTVFPGEIYQAPKTWAER
AYPTLKYYNVVNKGGHFAAWEEPELFASELRKAFKPYR
>Mature_437_residues
SIRHASPLNSIAVAVLLSAGTLMSVSPFAHAQNGATATVGAVVGDTAIRPFKVEIPEDAIIDLKKRVLATRWPDPETVKD
QSQGVQQDKLKALVDYWGKDYDWHKVQNKLNALPMYITRIDGVDIQFIHVKSKHPNALPLLLTHGWPGSILEFTKSIAPL
TDPTSYGGRAEDAFDVIIPSMPGYGFSQRPTEGGWGPERMGAAWDVLMKRLGYKNYVSQGGDWGSVVADAMGRQAPSGLR
AIHVNMPATVPPEIARAINDGTPPPAGITPEEKAAYQSLKDFFGKNAAYGSMMSTRPQTVGYALSDSPAGLAAWIFDKFN
QWTYSGGDAEKSLSKDEMLDDISLYWLTNSAVSSARLYWENNNNNFNSVEQKTREIKVPVAVTVFPGEIYQAPKTWAERA
YPTLKYYNVVNKGGHFAAWEEPELFASELRKAFKPYR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

Organism=Homo sapiens, GI4503583, Length=415, Percent_Identity=36.3855421686747, Blast_Score=282, Evalue=4e-76,
Organism=Homo sapiens, GI209862837, Length=415, Percent_Identity=36.3855421686747, Blast_Score=282, Evalue=4e-76,
Organism=Caenorhabditis elegans, GI17564944, Length=443, Percent_Identity=32.5056433408578, Blast_Score=224, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI193207462, Length=410, Percent_Identity=26.8292682926829, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24655327, Length=413, Percent_Identity=32.2033898305085, Blast_Score=195, Evalue=5e-50,
Organism=Drosophila melanogaster, GI20130139, Length=409, Percent_Identity=30.8068459657702, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI19922580, Length=406, Percent_Identity=30.5418719211823, Blast_Score=190, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 48259; Mature: 48128

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRHASPLNSIAVAVLLSAGTLMSVSPFAHAQNGATATVGAVVGDTAIRPFKVEIPEDA
CCCCCCCCHHHHHHHHHHHCCCCEECCCCHHCCCCCCEEHHHHHCCCCCCCEEEECCCHH
IIDLKKRVLATRWPDPETVKDQSQGVQQDKLKALVDYWGKDYDWHKVQNKLNALPMYITR
HHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEE
IDGVDIQFIHVKSKHPNALPLLLTHGWPGSILEFTKSIAPLTDPTSYGGRAEDAFDVIIP
ECCCEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEC
SMPGYGFSQRPTEGGWGPERMGAAWDVLMKRLGYKNYVSQGGDWGSVVADAMGRQAPSGL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHCCCCCCCC
RAIHVNMPATVPPEIARAINDGTPPPAGITPEEKAAYQSLKDFFGKNAAYGSMMSTRPQT
EEEEECCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCC
VGYALSDSPAGLAAWIFDKFNQWTYSGGDAEKSLSKDEMLDDISLYWLTNSAVSSARLYW
CEEEECCCCCHHHHHHHHHHCCCEECCCCHHHHCCHHHHHHCEEEEEEECCCCCCEEEEE
ENNNNNFNSVEQKTREIKVPVAVTVFPGEIYQAPKTWAERAYPTLKYYNVVNKGGHFAAW
ECCCCCCHHHHHHHHEEECCEEEEEECHHHHHCCHHHHHHCCCCEEEHHHHCCCCCCCCC
EEPELFASELRKAFKPYR
CCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SIRHASPLNSIAVAVLLSAGTLMSVSPFAHAQNGATATVGAVVGDTAIRPFKVEIPEDA
CCCCCCCHHHHHHHHHHHCCCCEECCCCHHCCCCCCEEHHHHHCCCCCCCEEEECCCHH
IIDLKKRVLATRWPDPETVKDQSQGVQQDKLKALVDYWGKDYDWHKVQNKLNALPMYITR
HHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEE
IDGVDIQFIHVKSKHPNALPLLLTHGWPGSILEFTKSIAPLTDPTSYGGRAEDAFDVIIP
ECCCEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEC
SMPGYGFSQRPTEGGWGPERMGAAWDVLMKRLGYKNYVSQGGDWGSVVADAMGRQAPSGL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHCCCCCCCC
RAIHVNMPATVPPEIARAINDGTPPPAGITPEEKAAYQSLKDFFGKNAAYGSMMSTRPQT
EEEEECCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCC
VGYALSDSPAGLAAWIFDKFNQWTYSGGDAEKSLSKDEMLDDISLYWLTNSAVSSARLYW
CEEEECCCCCHHHHHHHHHHCCCEECCCCHHHHCCHHHHHHCEEEEEEECCCCCCEEEEE
ENNNNNFNSVEQKTREIKVPVAVTVFPGEIYQAPKTWAERAYPTLKYYNVVNKGGHFAAW
ECCCCCCHHHHHHHHEEECCEEEEEECHHHHHCCHHHHHHCCCCEEEHHHHCCCCCCCCC
EEPELFASELRKAFKPYR
CCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226695 [H]