Click here to switch to the map view.

The map label for this gene is hupA [H]

Identifier: 77461821

GI number: 77461821

Start: 6273921

End: 6274196

Strand: Reverse

Name: hupA [H]

Synonym: Pfl01_5600

Alternate gene names: 77461821

Gene position: 6274196-6273921 (Counterclockwise)

Preceding gene: 77461822

Following gene: 77461817

Centisome position: 97.45

GC content: 58.33

Gene sequence:

>276_bases
ATGCGTAAACCAGAACTCGCCGCTGCAATCGCTGAAAAAGCGGATCTGACCAAAGAGCAGGCCAACCGCGTTCTCAACGC
CGTTCTCGAAGAAATCACCGGCGCCCTGCACCGCAAGGACAGCGTCACGCTGGTGGGCTTCGGCACCTTCCTGCAACGCC
ACCGCGGTGCCCGCACCGGCAAAAACCCGCAAACCGGTGAACCGGTGAAGATCAAGGCCAGCAACACCGTTGCGTTCAAG
CCAGGCAAATCGTTGAAAGACAGCGTTAATCCGTAA

Upstream 100 bases:

>100_bases
CTCCCGTCTGCCGCAGAGTAGAGCCTGCGGCGCCTTGGGCGCTGTTCCAACGAGAACAGCACGGACATAACAACAAAAAA
CCGTCAAAGGGGCTTCACTA

Downstream 100 bases:

>100_bases
TCGCGGCGAATGCCCGGTCAGCTGGGCGCGCTGCATGAAAAATGGGCATACCGATTGCGGTCGGATGCCCATTTTTTTGG
CTGATGGCGAGCCGAGCTGG

Product: nucleoid protein HU subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 91; Mature: 91

Protein sequence:

>91_residues
MRKPELAAAIAEKADLTKEQANRVLNAVLEEITGALHRKDSVTLVGFGTFLQRHRGARTGKNPQTGEPVKIKASNTVAFK
PGKSLKDSVNP

Sequences:

>Translated_91_residues
MRKPELAAAIAEKADLTKEQANRVLNAVLEEITGALHRKDSVTLVGFGTFLQRHRGARTGKNPQTGEPVKIKASNTVAFK
PGKSLKDSVNP
>Mature_91_residues
MRKPELAAAIAEKADLTKEQANRVLNAVLEEITGALHRKDSVTLVGFGTFLQRHRGARTGKNPQTGEPVKIKASNTVAFK
PGKSLKDSVNP

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=53.9325842696629, Blast_Score=93, Evalue=3e-21,
Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=47.7777777777778, Blast_Score=90, Evalue=3e-20,
Organism=Escherichia coli, GI1788005, Length=89, Percent_Identity=38.2022471910112, Blast_Score=67, Evalue=3e-13,

Paralogues:

None

Copy number: 1380 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9820; Mature: 9820

Theoretical pI: Translated: 10.95; Mature: 10.95

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKPELAAAIAEKADLTKEQANRVLNAVLEEITGALHRKDSVTLVGFGTFLQRHRGARTG
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCC
KNPQTGEPVKIKASNTVAFKPGKSLKDSVNP
CCCCCCCCEEEECCCEEEECCCCCCCCCCCC
>Mature Secondary Structure
MRKPELAAAIAEKADLTKEQANRVLNAVLEEITGALHRKDSVTLVGFGTFLQRHRGARTG
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCC
KNPQTGEPVKIKASNTVAFKPGKSLKDSVNP
CCCCCCCCEEEECCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]