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The map label for this gene is zraR [H]

Identifier: 77461804

GI number: 77461804

Start: 6254065

End: 6255591

Strand: Reverse

Name: zraR [H]

Synonym: Pfl01_5583

Alternate gene names: 77461804

Gene position: 6255591-6254065 (Counterclockwise)

Preceding gene: 77461805

Following gene: 77461803

Centisome position: 97.16

GC content: 64.77

Gene sequence:

>1527_bases
ATGTTCACTCAAGTGCCGCAGCCACTGCTCTATGCCGAAGCCTTGCTGGCGCAGTTCGCCAGCCTGTCGCGCGCGGCGGA
CGGTGCTGCGCTGCTGGGTGACTTCGTGCGCGGTCTGGCCGGGCTGAGCGGTTGCGAACTGACGCAGCTGTACTTGCTGG
ACGCCACGCACACGTCGCTGGGAATGAACGCCGAATGCCTCGACGGTGTGCTGCAACCGCGCAGCGCGGCGAGCCTGCCG
GCGGACTACAACGGCGAGCAACTGTTGCAGTTCGCCCTGTGCCAGAACCGCGTGGTGAGCTTCGACGACCTGGGCGGCAG
CCTGCACGAAACCAGTTTTCTGCCGGCGTCGTCCACGCCGTGGCAGTCGCTGTTGTGCGTGCCGCTGGTCAATCAGCAGA
AGGCCGTCGAAGGCCTTCTGCTGTGCGCAAGCCGTCGCCACATCGACCTGCAAGGCTTCGCCGATTCCCTCGGCCAGCTC
GGCTCGTTCGTGCTTGGTCAGCTGCATCTGCTGCAGCGTCTGCGCCAGCCAGTGGATGCGGCCGCGCCGGTCGTGCGCAG
CCTGCCGAGTGCCAGTGGCTATGGCCTGATCGGCAAGAGCGCGGCGATGCGCCAGACCTACTCGCTGATCAGCAAAGTCC
TGCACAGCCCGTACACCGTGCTGTTGCGTGGCGAGACCGGCACCGGCAAGGAAGTGGTCGCGCGGGCGATCCACGATTGC
GGCCCGCGCCGGTCCCAGGCGTTCATCGTGCAGAACTGCGCGGCGTTCCCGGAAAACCTGCTGGAAAGCGAGCTGTTCGG
CTACCGCAAAGGTGCGTTCACCGGCGCCGATCGCGACCGCGCCGGGCTGTTCGACGCGGCCAACGGCGGCACTCTGTTGC
TCGATGAAATCGGCGACATGCCGCTGTCGCTGCAAGCCAAATTGCTGCGTGTATTGCAGGAAGGCGAGATCCGTCCGCTG
GGTTCCAACGACACCCACAAGATCGACGTGCGAATTATCGCTGCGACGCACCGCGATCTGTCGGTGCTGGTCAGCGAAGG
CAAATTCCGTGAGGACCTGTACTACCGCCTCGCGCAATTTCCGATCGAGTTGCCGGCCCTGCGTCAGCGTGAAGGCGACA
TCCTCGACCTCGCCAAACACTTCGCCGACAAGGCCTGCACTTTCCTGCAACGTGATCCGGTGCGCTGGTCGGACGCAGCG
CTGGAACACCTGTCCGGTTACACCTTCCCCGGCAACGTGCGTGAACTCAAAGGTCTGGTCGAACGCGCGGTGCTGTTGTG
CGAGGGCGGCGAGTTGCTGGCCGAACATTTCTCGCTGCGCCTGGAATCGGCGCCAGCGCCGGAAGACCACTGCGGCCTCA
ATCTGCGCGAACGACTGGAAGCGGTCGAACGCAATCTGTTGCTCGATTGCCTGCGCAAGAACGACGGCAACCAGACGCTC
GCCGCCCGGGAACTGGGCTTGCCGCGCCGCACGCTGCTGTACCGGCTCGGCCGCTTGAACATCAATCTGGGTGATTTCGA
TGGGTAG

Upstream 100 bases:

>100_bases
TTGCTCGACGCCATGGCCACCGGTGAAAGCCTCAAGCGCGTGCATGCGACGCTCGACGGTGAAGCCAGCGTGACCTGCGA
GTTCGCCTGAGGTGAGTGTG

Downstream 100 bases:

>100_bases
GCGAAAGTCCGTCGGATTCACCTCGAACACCTATTTCAGCGCCGCCCGCAAGGGTCGGCGCTTTGTGCTTTGTCTACACC
TGGAGACCCTCTGATGTCTG

Product: Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MFTQVPQPLLYAEALLAQFASLSRAADGAALLGDFVRGLAGLSGCELTQLYLLDATHTSLGMNAECLDGVLQPRSAASLP
ADYNGEQLLQFALCQNRVVSFDDLGGSLHETSFLPASSTPWQSLLCVPLVNQQKAVEGLLLCASRRHIDLQGFADSLGQL
GSFVLGQLHLLQRLRQPVDAAAPVVRSLPSASGYGLIGKSAAMRQTYSLISKVLHSPYTVLLRGETGTGKEVVARAIHDC
GPRRSQAFIVQNCAAFPENLLESELFGYRKGAFTGADRDRAGLFDAANGGTLLLDEIGDMPLSLQAKLLRVLQEGEIRPL
GSNDTHKIDVRIIAATHRDLSVLVSEGKFREDLYYRLAQFPIELPALRQREGDILDLAKHFADKACTFLQRDPVRWSDAA
LEHLSGYTFPGNVRELKGLVERAVLLCEGGELLAEHFSLRLESAPAPEDHCGLNLRERLEAVERNLLLDCLRKNDGNQTL
AARELGLPRRTLLYRLGRLNINLGDFDG

Sequences:

>Translated_508_residues
MFTQVPQPLLYAEALLAQFASLSRAADGAALLGDFVRGLAGLSGCELTQLYLLDATHTSLGMNAECLDGVLQPRSAASLP
ADYNGEQLLQFALCQNRVVSFDDLGGSLHETSFLPASSTPWQSLLCVPLVNQQKAVEGLLLCASRRHIDLQGFADSLGQL
GSFVLGQLHLLQRLRQPVDAAAPVVRSLPSASGYGLIGKSAAMRQTYSLISKVLHSPYTVLLRGETGTGKEVVARAIHDC
GPRRSQAFIVQNCAAFPENLLESELFGYRKGAFTGADRDRAGLFDAANGGTLLLDEIGDMPLSLQAKLLRVLQEGEIRPL
GSNDTHKIDVRIIAATHRDLSVLVSEGKFREDLYYRLAQFPIELPALRQREGDILDLAKHFADKACTFLQRDPVRWSDAA
LEHLSGYTFPGNVRELKGLVERAVLLCEGGELLAEHFSLRLESAPAPEDHCGLNLRERLEAVERNLLLDCLRKNDGNQTL
AARELGLPRRTLLYRLGRLNINLGDFDG
>Mature_508_residues
MFTQVPQPLLYAEALLAQFASLSRAADGAALLGDFVRGLAGLSGCELTQLYLLDATHTSLGMNAECLDGVLQPRSAASLP
ADYNGEQLLQFALCQNRVVSFDDLGGSLHETSFLPASSTPWQSLLCVPLVNQQKAVEGLLLCASRRHIDLQGFADSLGQL
GSFVLGQLHLLQRLRQPVDAAAPVVRSLPSASGYGLIGKSAAMRQTYSLISKVLHSPYTVLLRGETGTGKEVVARAIHDC
GPRRSQAFIVQNCAAFPENLLESELFGYRKGAFTGADRDRAGLFDAANGGTLLLDEIGDMPLSLQAKLLRVLQEGEIRPL
GSNDTHKIDVRIIAATHRDLSVLVSEGKFREDLYYRLAQFPIELPALRQREGDILDLAKHFADKACTFLQRDPVRWSDAA
LEHLSGYTFPGNVRELKGLVERAVLLCEGGELLAEHFSLRLESAPAPEDHCGLNLRERLEAVERNLLLDCLRKNDGNQTL
AARELGLPRRTLLYRLGRLNINLGDFDG

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG3604

COG function: function code KT; Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=413, Percent_Identity=41.4043583535109, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1788550, Length=331, Percent_Identity=45.0151057401813, Blast_Score=269, Evalue=2e-73,
Organism=Escherichia coli, GI87082117, Length=322, Percent_Identity=46.8944099378882, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1789087, Length=315, Percent_Identity=46.984126984127, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1788905, Length=294, Percent_Identity=45.9183673469388, Blast_Score=233, Evalue=3e-62,
Organism=Escherichia coli, GI1789233, Length=316, Percent_Identity=43.3544303797468, Blast_Score=232, Evalue=5e-62,
Organism=Escherichia coli, GI87082152, Length=320, Percent_Identity=44.6875, Blast_Score=231, Evalue=7e-62,
Organism=Escherichia coli, GI1790299, Length=330, Percent_Identity=40, Blast_Score=222, Evalue=6e-59,
Organism=Escherichia coli, GI1786524, Length=325, Percent_Identity=40.9230769230769, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI87081872, Length=306, Percent_Identity=38.562091503268, Blast_Score=188, Evalue=7e-49,
Organism=Escherichia coli, GI1787583, Length=294, Percent_Identity=36.0544217687075, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789828, Length=248, Percent_Identity=38.3064516129032, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI87081858, Length=295, Percent_Identity=31.1864406779661, Blast_Score=125, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 55487; Mature: 55487

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTQVPQPLLYAEALLAQFASLSRAADGAALLGDFVRGLAGLSGCELTQLYLLDATHTSL
CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCC
GMNAECLDGVLQPRSAASLPADYNGEQLLQFALCQNRVVSFDDLGGSLHETSFLPASSTP
CCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCCHHHCCCCCCCCCC
WQSLLCVPLVNQQKAVEGLLLCASRRHIDLQGFADSLGQLGSFVLGQLHLLQRLRQPVDA
HHHEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AAPVVRSLPSASGYGLIGKSAAMRQTYSLISKVLHSPYTVLLRGETGTGKEVVARAIHDC
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHC
GPRRSQAFIVQNCAAFPENLLESELFGYRKGAFTGADRDRAGLFDAANGGTLLLDEIGDM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEHHHCCC
PLSLQAKLLRVLQEGEIRPLGSNDTHKIDVRIIAATHRDLSVLVSEGKFREDLYYRLAQF
CHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHCCCHHHHHHHHHHHC
PIELPALRQREGDILDLAKHFADKACTFLQRDPVRWSDAALEHLSGYTFPGNVRELKGLV
CCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHH
ERAVLLCEGGELLAEHFSLRLESAPAPEDHCGLNLRERLEAVERNLLLDCLRKNDGNQTL
HHHHHHCCCHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCH
AARELGLPRRTLLYRLGRLNINLGDFDG
HHHHHCCCHHHHHHHHHCCEECCCCCCC
>Mature Secondary Structure
MFTQVPQPLLYAEALLAQFASLSRAADGAALLGDFVRGLAGLSGCELTQLYLLDATHTSL
CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCC
GMNAECLDGVLQPRSAASLPADYNGEQLLQFALCQNRVVSFDDLGGSLHETSFLPASSTP
CCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCCHHHCCCCCCCCCC
WQSLLCVPLVNQQKAVEGLLLCASRRHIDLQGFADSLGQLGSFVLGQLHLLQRLRQPVDA
HHHEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AAPVVRSLPSASGYGLIGKSAAMRQTYSLISKVLHSPYTVLLRGETGTGKEVVARAIHDC
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHC
GPRRSQAFIVQNCAAFPENLLESELFGYRKGAFTGADRDRAGLFDAANGGTLLLDEIGDM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEHHHCCC
PLSLQAKLLRVLQEGEIRPLGSNDTHKIDVRIIAATHRDLSVLVSEGKFREDLYYRLAQF
CHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHCCCHHHHHHHHHHHC
PIELPALRQREGDILDLAKHFADKACTFLQRDPVRWSDAALEHLSGYTFPGNVRELKGLV
CCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHH
ERAVLLCEGGELLAEHFSLRLESAPAPEDHCGLNLRERLEAVERNLLLDCLRKNDGNQTL
HHHHHHCCCHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCH
AARELGLPRRTLLYRLGRLNINLGDFDG
HHHHHCCCHHHHHHHHHCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]