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The map label for this gene is exuR [H]

Identifier: 77461679

GI number: 77461679

Start: 6125156

End: 6125863

Strand: Reverse

Name: exuR [H]

Synonym: Pfl01_5458

Alternate gene names: 77461679

Gene position: 6125863-6125156 (Counterclockwise)

Preceding gene: 77461685

Following gene: 77461678

Centisome position: 95.15

GC content: 65.11

Gene sequence:

>708_bases
ATGAACTCGATCTCCCGCGCCGTACCCGAAGTGGCGCTGCAAGCGATCCGCAAACTGATTACCGAGCAGGGCTTCGGCCC
CGGCGATGCGTTGCCCTCGCAACGGGATCTGGCGGTTCAGCTGGGCGTCAGCCGCGCTTCGTTGCGTGAGGCGTTGTCGT
CATTGAGCGCGCTGGGTGTGGTCAGCATCCAGCCGGGCAAAGGCGTGTTCGTGCAGGCACCGGTGGAGCTGCCGCGTGGC
GAGGGCGCGCCGGCCTGGCCGTTTGCCGCCCAGGCTTCGCCGCTGGAAATCTTTCAGTTGCGCTATGCGCTGGAAGGGTT
TGCGGCCGGTCTGGCGGCGGTGACGCTGAGCACGTTTGATCTGGACGAACTGGAAGACAACGTTGCCGCCATGCGCGAGC
AACTGCGCGTCGGTGACTTCGAGGCAGCGGCGAAACTGGATTTCGAATTCCACCGGCGGATCCTGCTGGCCAGCGGCAAT
CAGGCGATGCTGAGCATCCTCACCGCCAGCGCCGACATCTTTCTGGAGAGCCAGAAACTACCGTTCATCCGCGCCGAGCG
GGCCATGGAAACCTGGCAGGAACACCGCAAGATCCTTCGCGCACTGGCCCGTCGGGCGTCAGCCGCTGCACAGAAAGCCA
TGCAGGAGCACGTGCGCAACGCGGCCCTGCGTACCGGAATTTCCTTCATCGCCCCCGCCAGCGCGTGA

Upstream 100 bases:

>100_bases
CATCGGCTTGCGCCGCCGAACCCCGCTGGGGCACGACTTGCCTGATCCTTCGAATAGCATTACAACTGGCCGCACCTTGG
CCTGGTCCGTCTGGAAAACC

Downstream 100 bases:

>100_bases
CTTGAGCTATACCCAAACTCATCGAGTGCCATAGCAAGACTCAATCATCTGCGGCTTCCTGAACAAGGGAAGGGCGGCTA
TGATGGGCCACGTTTTTTTG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MNSISRAVPEVALQAIRKLITEQGFGPGDALPSQRDLAVQLGVSRASLREALSSLSALGVVSIQPGKGVFVQAPVELPRG
EGAPAWPFAAQASPLEIFQLRYALEGFAAGLAAVTLSTFDLDELEDNVAAMREQLRVGDFEAAAKLDFEFHRRILLASGN
QAMLSILTASADIFLESQKLPFIRAERAMETWQEHRKILRALARRASAAAQKAMQEHVRNAALRTGISFIAPASA

Sequences:

>Translated_235_residues
MNSISRAVPEVALQAIRKLITEQGFGPGDALPSQRDLAVQLGVSRASLREALSSLSALGVVSIQPGKGVFVQAPVELPRG
EGAPAWPFAAQASPLEIFQLRYALEGFAAGLAAVTLSTFDLDELEDNVAAMREQLRVGDFEAAAKLDFEFHRRILLASGN
QAMLSILTASADIFLESQKLPFIRAERAMETWQEHRKILRALARRASAAAQKAMQEHVRNAALRTGISFIAPASA
>Mature_235_residues
MNSISRAVPEVALQAIRKLITEQGFGPGDALPSQRDLAVQLGVSRASLREALSSLSALGVVSIQPGKGVFVQAPVELPRG
EGAPAWPFAAQASPLEIFQLRYALEGFAAGLAAVTLSTFDLDELEDNVAAMREQLRVGDFEAAAKLDFEFHRRILLASGN
QAMLSILTASADIFLESQKLPFIRAERAMETWQEHRKILRALARRASAAAQKAMQEHVRNAALRTGISFIAPASA

Specific function: Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the exuT, uxaCA and uxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082208, Length=211, Percent_Identity=29.3838862559242, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1789353, Length=228, Percent_Identity=28.5087719298246, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790780, Length=223, Percent_Identity=27.8026905829596, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1786303, Length=164, Percent_Identity=31.0975609756098, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790032, Length=220, Percent_Identity=28.1818181818182, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25331; Mature: 25331

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS50949 HTH_GNTR ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSISRAVPEVALQAIRKLITEQGFGPGDALPSQRDLAVQLGVSRASLREALSSLSALGV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCE
VSIQPGKGVFVQAPVELPRGEGAPAWPFAAQASPLEIFQLRYALEGFAAGLAAVTLSTFD
EEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LDELEDNVAAMREQLRVGDFEAAAKLDFEFHRRILLASGNQAMLSILTASADIFLESQKL
HHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHEEEEECCCHHHHHHHHHHHHHEEECCCC
PFIRAERAMETWQEHRKILRALARRASAAAQKAMQEHVRNAALRTGISFIAPASA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCC
>Mature Secondary Structure
MNSISRAVPEVALQAIRKLITEQGFGPGDALPSQRDLAVQLGVSRASLREALSSLSALGV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCE
VSIQPGKGVFVQAPVELPRGEGAPAWPFAAQASPLEIFQLRYALEGFAAGLAAVTLSTFD
EEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LDELEDNVAAMREQLRVGDFEAAAKLDFEFHRRILLASGNQAMLSILTASADIFLESQKL
HHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHEEEEECCCHHHHHHHHHHHHHEEECCCC
PFIRAERAMETWQEHRKILRALARRASAAAQKAMQEHVRNAALRTGISFIAPASA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA