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The map label for this gene is hlyB [H]

Identifier: 77459992

GI number: 77459992

Start: 4266550

End: 4268697

Strand: Direct

Name: hlyB [H]

Synonym: Pfl01_3770

Alternate gene names: 77459992

Gene position: 4266550-4268697 (Clockwise)

Preceding gene: 77459989

Following gene: 77459997

Centisome position: 66.27

GC content: 62.99

Gene sequence:

>2148_bases
ATGTCACTCAGACAACTTTCCATCCAATGGAAAATCACCCTGCTCGCCGGGCTCTGCCTGGCCGGTATCGTGACCCTGTT
GGTGGGTCTTTCGCTGTATCGCATGGAGCACAGTTCCGAACTGGTGAAAGCTTCGAGCATGGAAATGCTCACCGAATCGG
CCCAGGCCCGCATCGAATCCCAGGGCGAAGTCCAGGCAGCGGGTATTCGCCAGCAGTTCATGGACGCCTATCAATATGGC
CACGGTTTCTCGCGTCAGGTGCTGTTTCTGCGTGAGCAGGCCGAGAAGCGCTTCCTTGATGCCTTCGACCTGCGCGAGGA
CATGACCCGTCAGGTGAAATCGGCACTGCAGGCCAACCCGGATCTGCTCGGCCTGTCGCTGGTGTTCGAAGCCAATGCGC
TGGACGGCAAGGACGAACTGTTTGCCGGTCAGGCTGAACTGGGCAGCAACGACAAGGGCCGCTTCGCCCTGTACTGGTCG
CAGCCGACCCCGGGCAAAGTGACCTCGATGGCGCTGCCGGAAAGCGACATGGCCGACACCAGCACCGGCCCCAGCGGTCA
GGCCGCCAACGCCTGGTTCACCTGCCCGCGCACCACGCTCAAGCCGTGCGTGATCGAACCCTACTTCTATGTGATCGACG
GGCAAAAGGTGCTGATGACCAGCATCGTGTTCCCGCTGATGGTCAACGGCAAAGTCATCGCCTCGCTGTCGGTGGACATC
AACCTCAACAGCCTGCAAGCGATCAGCCAGAGCGCCAGCAAAAAGCTCTACGACGGCCAGACCGCCGTGAGCATCGTCAG
CCCCGCCGGCCTGCTCGCCGGTTACAGCCCGGACGCCAATAAACTCAGCCAGCGCCTGGATGCCGTGGACACCACCAGCG
GCGCCGAACTGCTGCGTCTGCTCGCCTCGAACCAAACCGTCAGCAGCCTGCACAGCAACGCGCAACTGAAAGTGCTGTCG
CCGTTCCAGCCGATTCCCGGTGGCCCGTCGTGGGGCGTACTGCTCGATGTGCCGGAAAAAGTTTTGGTGGAACGCGCCGA
AGCGCTCAAGCAACAACTGGATGCCAGCAATACTTCGGGCACCCTGATCGAACTGAGCCTCGGCGTGCTTGCCGCGCTGA
TCGGCCTGTTGCTGGTGTGGCTGATGGCCCGCAGCGTGACCAAGCCGATCCTAGGCGTAGCGCACATGCTCGAAGACATC
GCCAGCGGCGAAGGCGACCTGACCCGACGTCTGGCCTACGACAAGAAGGACGAACTCGGTCAACTGGCCGGCTGGTTCAA
CCGCTTCCTCGACAAGCTGCAACCGATCATCGCCGAGGTGAAACGCTCGGTGCAGGATGCGCGCAACACTGCCGATCAGT
CTTCGGCGATTGCCACCCAGACCAGTGCCGGCATGGAACAGCAATACCGTCAGGTCGATCAGGTCGCCACCGCGTCCCAC
GAAATGAGCGCCACCGCCCAGGACGTGGCCCGCAGCGCGGCACAAGCCGCCGAAGCCGCCAAGGACGCCGACCGCGCCAC
CCGTCAGGGCCTGACCGTGATCGACCGCACCACCGCCAGCATCGACACCCTCGCCGCCGACATGAGCGCAGCGATGGTGC
AGGTCGAAGGCCTGGCCGCCAACAGCGAGAAGATCGGTACCGTGCTGGAAACCATCCGCGCCATCGCCGAACAGACCAAC
CTGCTGGCCCTCAACGCCGCCATTGAAGCCGCCCGTGCCGGCGAGGCCGGACGTGGTTTTGCGGTGGTCGCCGACGAAGT
GCGCAACCTCGCCCGCCGCACTCAAGAGTCGGTGGAAGAAACCCGCCAGGTGATCGAGCAATTGCAGAATGGCACCCAGG
ACGTGGTCGGCTCGATGGGCAACAGCCATCGCCAGGCCCAGGGCAGTGTCGAACAGGTGGGTCAAGCGGTTACCGCGCTG
CGCCAGATCGGCGATGCGGTGACGGTGATCAGCGACATGAACCTGCAGATCGCCAGCGCCGCCGAAGAGCAGAGCGCGGT
GGCTGAAGAGATCAACAACAACGTGGCGACGATTCGTGATGTGACGGAGTCGCTGTCGGGGCAGGCGAATGAATCGGCGC
GGGTGAGTCAGTCGCTCAATAGTCTGGCGAATCAGCAGCAGAGTCTGATGGATCAGTTTCGGGTCTAG

Upstream 100 bases:

>100_bases
CATGCGTCAATTCGCCCTATTGCATTGACGCCATAAAGAAAGCCGAAACGCGGCCGTTACAGTGCAAAGTCTCAGATATT
TATCGAATAAGGACGTTTCC

Downstream 100 bases:

>100_bases
GGTTCATCGCAAAGTCCCTGTGGGAGCCCGCCTGGCTGCTCCCACAGGTTTGTGGAATGACGGAAATCAGCGTTTAGGCA
ATTCGATCACCACCTTCAAA

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 715; Mature: 714

Protein sequence:

>715_residues
MSLRQLSIQWKITLLAGLCLAGIVTLLVGLSLYRMEHSSELVKASSMEMLTESAQARIESQGEVQAAGIRQQFMDAYQYG
HGFSRQVLFLREQAEKRFLDAFDLREDMTRQVKSALQANPDLLGLSLVFEANALDGKDELFAGQAELGSNDKGRFALYWS
QPTPGKVTSMALPESDMADTSTGPSGQAANAWFTCPRTTLKPCVIEPYFYVIDGQKVLMTSIVFPLMVNGKVIASLSVDI
NLNSLQAISQSASKKLYDGQTAVSIVSPAGLLAGYSPDANKLSQRLDAVDTTSGAELLRLLASNQTVSSLHSNAQLKVLS
PFQPIPGGPSWGVLLDVPEKVLVERAEALKQQLDASNTSGTLIELSLGVLAALIGLLLVWLMARSVTKPILGVAHMLEDI
ASGEGDLTRRLAYDKKDELGQLAGWFNRFLDKLQPIIAEVKRSVQDARNTADQSSAIATQTSAGMEQQYRQVDQVATASH
EMSATAQDVARSAAQAAEAAKDADRATRQGLTVIDRTTASIDTLAADMSAAMVQVEGLAANSEKIGTVLETIRAIAEQTN
LLALNAAIEAARAGEAGRGFAVVADEVRNLARRTQESVEETRQVIEQLQNGTQDVVGSMGNSHRQAQGSVEQVGQAVTAL
RQIGDAVTVISDMNLQIASAAEEQSAVAEEINNNVATIRDVTESLSGQANESARVSQSLNSLANQQQSLMDQFRV

Sequences:

>Translated_715_residues
MSLRQLSIQWKITLLAGLCLAGIVTLLVGLSLYRMEHSSELVKASSMEMLTESAQARIESQGEVQAAGIRQQFMDAYQYG
HGFSRQVLFLREQAEKRFLDAFDLREDMTRQVKSALQANPDLLGLSLVFEANALDGKDELFAGQAELGSNDKGRFALYWS
QPTPGKVTSMALPESDMADTSTGPSGQAANAWFTCPRTTLKPCVIEPYFYVIDGQKVLMTSIVFPLMVNGKVIASLSVDI
NLNSLQAISQSASKKLYDGQTAVSIVSPAGLLAGYSPDANKLSQRLDAVDTTSGAELLRLLASNQTVSSLHSNAQLKVLS
PFQPIPGGPSWGVLLDVPEKVLVERAEALKQQLDASNTSGTLIELSLGVLAALIGLLLVWLMARSVTKPILGVAHMLEDI
ASGEGDLTRRLAYDKKDELGQLAGWFNRFLDKLQPIIAEVKRSVQDARNTADQSSAIATQTSAGMEQQYRQVDQVATASH
EMSATAQDVARSAAQAAEAAKDADRATRQGLTVIDRTTASIDTLAADMSAAMVQVEGLAANSEKIGTVLETIRAIAEQTN
LLALNAAIEAARAGEAGRGFAVVADEVRNLARRTQESVEETRQVIEQLQNGTQDVVGSMGNSHRQAQGSVEQVGQAVTAL
RQIGDAVTVISDMNLQIASAAEEQSAVAEEINNNVATIRDVTESLSGQANESARVSQSLNSLANQQQSLMDQFRV
>Mature_714_residues
SLRQLSIQWKITLLAGLCLAGIVTLLVGLSLYRMEHSSELVKASSMEMLTESAQARIESQGEVQAAGIRQQFMDAYQYGH
GFSRQVLFLREQAEKRFLDAFDLREDMTRQVKSALQANPDLLGLSLVFEANALDGKDELFAGQAELGSNDKGRFALYWSQ
PTPGKVTSMALPESDMADTSTGPSGQAANAWFTCPRTTLKPCVIEPYFYVIDGQKVLMTSIVFPLMVNGKVIASLSVDIN
LNSLQAISQSASKKLYDGQTAVSIVSPAGLLAGYSPDANKLSQRLDAVDTTSGAELLRLLASNQTVSSLHSNAQLKVLSP
FQPIPGGPSWGVLLDVPEKVLVERAEALKQQLDASNTSGTLIELSLGVLAALIGLLLVWLMARSVTKPILGVAHMLEDIA
SGEGDLTRRLAYDKKDELGQLAGWFNRFLDKLQPIIAEVKRSVQDARNTADQSSAIATQTSAGMEQQYRQVDQVATASHE
MSATAQDVARSAAQAAEAAKDADRATRQGLTVIDRTTASIDTLAADMSAAMVQVEGLAANSEKIGTVLETIRAIAEQTNL
LALNAAIEAARAGEAGRGFAVVADEVRNLARRTQESVEETRQVIEQLQNGTQDVVGSMGNSHRQAQGSVEQVGQAVTALR
QIGDAVTVISDMNLQIASAAEEQSAVAEEINNNVATIRDVTESLSGQANESARVSQSLNSLANQQQSLMDQFRV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=326, Percent_Identity=32.8220858895706, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1788194, Length=348, Percent_Identity=30.4597701149425, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI1787690, Length=438, Percent_Identity=27.1689497716895, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI1788195, Length=302, Percent_Identity=31.7880794701987, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1789453, Length=258, Percent_Identity=31.7829457364341, Blast_Score=102, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 76698; Mature: 76566

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRQLSIQWKITLLAGLCLAGIVTLLVGLSLYRMEHSSELVKASSMEMLTESAQARIES
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QGEVQAAGIRQQFMDAYQYGHGFSRQVLFLREQAEKRFLDAFDLREDMTRQVKSALQANP
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DLLGLSLVFEANALDGKDELFAGQAELGSNDKGRFALYWSQPTPGKVTSMALPESDMADT
CEEEEEEEEECCCCCCCHHHEECCHHCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCC
STGPSGQAANAWFTCPRTTLKPCVIEPYFYVIDGQKVLMTSIVFPLMVNGKVIASLSVDI
CCCCCCCCCCCEEECCCCCCCCEEECCEEEEECCCHHHHHHHHHHHHCCCEEEEEEEEEE
NLNSLQAISQSASKKLYDGQTAVSIVSPAGLLAGYSPDANKLSQRLDAVDTTSGAELLRL
CHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHH
LASNQTVSSLHSNAQLKVLSPFQPIPGGPSWGVLLDVPEKVLVERAEALKQQLDASNTSG
HHCCCHHHHHHCCCEEEEECCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCC
TLIELSLGVLAALIGLLLVWLMARSVTKPILGVAHMLEDIASGEGDLTRRLAYDKKDELG
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHH
QLAGWFNRFLDKLQPIIAEVKRSVQDARNTADQSSAIATQTSAGMEQQYRQVDQVATASH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMSATAQDVARSAAQAAEAAKDADRATRQGLTVIDRTTASIDTLAADMSAAMVQVEGLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCC
NSEKIGTVLETIRAIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLARRTQESVEE
CHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TRQVIEQLQNGTQDVVGSMGNSHRQAQGSVEQVGQAVTALRQIGDAVTVISDMNLQIASA
HHHHHHHHHCCHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHH
AEEQSAVAEEINNNVATIRDVTESLSGQANESARVSQSLNSLANQQQSLMDQFRV
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLRQLSIQWKITLLAGLCLAGIVTLLVGLSLYRMEHSSELVKASSMEMLTESAQARIES
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QGEVQAAGIRQQFMDAYQYGHGFSRQVLFLREQAEKRFLDAFDLREDMTRQVKSALQANP
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DLLGLSLVFEANALDGKDELFAGQAELGSNDKGRFALYWSQPTPGKVTSMALPESDMADT
CEEEEEEEEECCCCCCCHHHEECCHHCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCC
STGPSGQAANAWFTCPRTTLKPCVIEPYFYVIDGQKVLMTSIVFPLMVNGKVIASLSVDI
CCCCCCCCCCCEEECCCCCCCCEEECCEEEEECCCHHHHHHHHHHHHCCCEEEEEEEEEE
NLNSLQAISQSASKKLYDGQTAVSIVSPAGLLAGYSPDANKLSQRLDAVDTTSGAELLRL
CHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHH
LASNQTVSSLHSNAQLKVLSPFQPIPGGPSWGVLLDVPEKVLVERAEALKQQLDASNTSG
HHCCCHHHHHHCCCEEEEECCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCC
TLIELSLGVLAALIGLLLVWLMARSVTKPILGVAHMLEDIASGEGDLTRRLAYDKKDELG
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHH
QLAGWFNRFLDKLQPIIAEVKRSVQDARNTADQSSAIATQTSAGMEQQYRQVDQVATASH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMSATAQDVARSAAQAAEAAKDADRATRQGLTVIDRTTASIDTLAADMSAAMVQVEGLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCC
NSEKIGTVLETIRAIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLARRTQESVEE
CHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TRQVIEQLQNGTQDVVGSMGNSHRQAQGSVEQVGQAVTALRQIGDAVTVISDMNLQIASA
HHHHHHHHHCCHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHH
AEEQSAVAEEINNNVATIRDVTESLSGQANESARVSQSLNSLANQQQSLMDQFRV
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]