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The map label for this gene is yafC [C]

Identifier: 77459989

GI number: 77459989

Start: 4261888

End: 4262823

Strand: Direct

Name: yafC [C]

Synonym: Pfl01_3767

Alternate gene names: 77459989

Gene position: 4261888-4262823 (Clockwise)

Preceding gene: 77459985

Following gene: 77459992

Centisome position: 66.19

GC content: 64.32

Gene sequence:

>936_bases
ATGCACGGGCTCAACGAACTGGGATTCAAGGCGCTAAGGCTGTTTGTGGCCGTGCTCGATCACGGCAGCTTTTCCGAAGT
CGCCCGCCGCGAGGGCGTGGCGCCCTCCTCGATTTCCCGGCAGATCCAGTTGATGGAGCAAGCGCTGAACCAGCAATTGC
TCTACCGCCACACCCGCGCGGTGACGCCGACCGAAGCCGGGCGCATGCTCGGCCACCACGCGCGGCTGGTGCTGGTGCAA
CTGGAAGAAGCCGAACAGGCGTTGCAGGAACAGCAAAGCGAACCGACCGGTCTGGTGCGGATAAACGCCCCGGTGGTGTT
CGGCCAGCGCCACCTGACGCCATGGCTGGGCCGTTTGTGCGAGCGCTATCCGAAGCTGCAACTGGATATCCAGCAGACCG
ACCACTACATCGATCCGCTGCAGGAAGGCGCCGACCTGCTGTTTCGCATCGGCCCGCTGCACGACTCAAGCATGCAGGCG
CGGATCCTCGCGCCGCACCGCTTTCAAGTCGCGGCCAGCCCGGCGTATCTCAAGCGCTATGGCACGCCACAGCATCCCGA
CGACCTCGCCCGCCACCAGTGTCTGGCCTACAAGGGTGCGACCGGCCAGCAACGCTGGTTCTTCCGTCAGGATCAGGGCG
AGTGGGCGCCGTATGCAGTCAAGGGCCCGATCACCGGCAACCACGCGGACACGTTGACTCAGGCCGCTGTGCAAGGGCTG
GGGCTGGTGATGTTTCCGTCATGGCTGATCGGCGAGGCGGTGCGTGAGGGCACGCTGGTGCCGGTGCTGGGGGAGTATCA
GGTGTCGAACAGCGTGGAGCCGCAGCAGATTGCGGTGCTGTGGCCGGGGAGCCGGCGGTTGTCGGTGAAGGTGCGGACGG
TGATTGATTTCTTCATTGAGTGTTTTGGCGAGGTTCCTTATTGGGATCGTCCCTGA

Upstream 100 bases:

>100_bases
CTGAAGGAAACGATGGCGCGGATTATCGGCTGGCGCAGCTGTGCGATAAATGGGAGCATCCGGACAACACTTTTGCGCAA
TTCGCACAGCAGGACAGACG

Downstream 100 bases:

>100_bases
AGATCAAAAGCCCCCTCACCCTAGCCCTCTCCCGGAGGGAGAGGGAACCGAACGGGGGATATTCGAGAGATACGCCGACA
TGAGCGATCGGCTGTGAATC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MHGLNELGFKALRLFVAVLDHGSFSEVARREGVAPSSISRQIQLMEQALNQQLLYRHTRAVTPTEAGRMLGHHARLVLVQ
LEEAEQALQEQQSEPTGLVRINAPVVFGQRHLTPWLGRLCERYPKLQLDIQQTDHYIDPLQEGADLLFRIGPLHDSSMQA
RILAPHRFQVAASPAYLKRYGTPQHPDDLARHQCLAYKGATGQQRWFFRQDQGEWAPYAVKGPITGNHADTLTQAAVQGL
GLVMFPSWLIGEAVREGTLVPVLGEYQVSNSVEPQQIAVLWPGSRRLSVKVRTVIDFFIECFGEVPYWDRP

Sequences:

>Translated_311_residues
MHGLNELGFKALRLFVAVLDHGSFSEVARREGVAPSSISRQIQLMEQALNQQLLYRHTRAVTPTEAGRMLGHHARLVLVQ
LEEAEQALQEQQSEPTGLVRINAPVVFGQRHLTPWLGRLCERYPKLQLDIQQTDHYIDPLQEGADLLFRIGPLHDSSMQA
RILAPHRFQVAASPAYLKRYGTPQHPDDLARHQCLAYKGATGQQRWFFRQDQGEWAPYAVKGPITGNHADTLTQAAVQGL
GLVMFPSWLIGEAVREGTLVPVLGEYQVSNSVEPQQIAVLWPGSRRLSVKVRTVIDFFIECFGEVPYWDRP
>Mature_311_residues
MHGLNELGFKALRLFVAVLDHGSFSEVARREGVAPSSISRQIQLMEQALNQQLLYRHTRAVTPTEAGRMLGHHARLVLVQ
LEEAEQALQEQQSEPTGLVRINAPVVFGQRHLTPWLGRLCERYPKLQLDIQQTDHYIDPLQEGADLLFRIGPLHDSSMQA
RILAPHRFQVAASPAYLKRYGTPQHPDDLARHQCLAYKGATGQQRWFFRQDQGEWAPYAVKGPITGNHADTLTQAAVQGL
GLVMFPSWLIGEAVREGTLVPVLGEYQVSNSVEPQQIAVLWPGSRRLSVKVRTVIDFFIECFGEVPYWDRP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=299, Percent_Identity=31.1036789297659, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI87081978, Length=296, Percent_Identity=32.7702702702703, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI145693193, Length=302, Percent_Identity=31.4569536423841, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789440, Length=292, Percent_Identity=29.4520547945205, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789639, Length=298, Percent_Identity=28.8590604026846, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787128, Length=285, Percent_Identity=29.1228070175439, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1787589, Length=260, Percent_Identity=29.6153846153846, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1788297, Length=121, Percent_Identity=35.5371900826446, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789173, Length=263, Percent_Identity=25.4752851711027, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788706, Length=274, Percent_Identity=23.3576642335766, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786448, Length=264, Percent_Identity=25.7575757575758, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790011, Length=266, Percent_Identity=20.6766917293233, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787601, Length=172, Percent_Identity=26.1627906976744, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35067; Mature: 35067

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGLNELGFKALRLFVAVLDHGSFSEVARREGVAPSSISRQIQLMEQALNQQLLYRHTRA
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
VTPTEAGRMLGHHARLVLVQLEEAEQALQEQQSEPTGLVRINAPVVFGQRHLTPWLGRLC
CCCHHHHHHHCCCEEEEEEEHHHHHHHHHHHCCCCCEEEEECCCEEECCCCCCHHHHHHH
ERYPKLQLDIQQTDHYIDPLQEGADLLFRIGPLHDSSMQARILAPHRFQVAASPAYLKRY
HHCCCEEEEHHHHHHHHCHHHHCCCEEEEECCCCCCCCCEEEECCCEEEEECCHHHHHHC
GTPQHPDDLARHQCLAYKGATGQQRWFFRQDQGEWAPYAVKGPITGNHADTLTQAAVQGL
CCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHC
GLVMFPSWLIGEAVREGTLVPVLGEYQVSNSVEPQQIAVLWPGSRRLSVKVRTVIDFFIE
CHHHHHHHHHHHHHHCCCEEEEECCEECCCCCCCCEEEEECCCCCEEEEHHHHHHHHHHH
CFGEVPYWDRP
HHCCCCCCCCC
>Mature Secondary Structure
MHGLNELGFKALRLFVAVLDHGSFSEVARREGVAPSSISRQIQLMEQALNQQLLYRHTRA
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
VTPTEAGRMLGHHARLVLVQLEEAEQALQEQQSEPTGLVRINAPVVFGQRHLTPWLGRLC
CCCHHHHHHHCCCEEEEEEEHHHHHHHHHHHCCCCCEEEEECCCEEECCCCCCHHHHHHH
ERYPKLQLDIQQTDHYIDPLQEGADLLFRIGPLHDSSMQARILAPHRFQVAASPAYLKRY
HHCCCEEEEHHHHHHHHCHHHHCCCEEEEECCCCCCCCCEEEECCCEEEEECCHHHHHHC
GTPQHPDDLARHQCLAYKGATGQQRWFFRQDQGEWAPYAVKGPITGNHADTLTQAAVQGL
CCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHC
GLVMFPSWLIGEAVREGTLVPVLGEYQVSNSVEPQQIAVLWPGSRRLSVKVRTVIDFFIE
CHHHHHHHHHHHHHHCCCEEEEECCEECCCCCCCCEEEEECCCCCEEEEHHHHHHHHHHH
CFGEVPYWDRP
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]