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The map label for this gene is tsx [H]

Identifier: 77459979

GI number: 77459979

Start: 4255409

End: 4256368

Strand: Direct

Name: tsx [H]

Synonym: Pfl01_3757

Alternate gene names: 77459979

Gene position: 4255409-4256368 (Clockwise)

Preceding gene: 77459975

Following gene: 77459980

Centisome position: 66.09

GC content: 60.31

Gene sequence:

>960_bases
ATGCACGCTTTTTCCTGCCACCGCCTTCGCGGTGCGCGCACTTTTGCTGTTTCCCTGCTACTGGCCGGCGTTACCGGAGT
TCTCAGCCACACCGCGCTGGCGCAACCGGTCTTGCCCGATGAATCCGCCCAAGGTGAAGCCCTCAGCCCCGAAGCCAGCC
CGCCGAAAAAAGGCGCGTACCTGTCGGACTGGTACAACCAGGATCTGATGCTGATCGGCAGCAAGGACATCAGTTTCGGT
CCGCAACCGGCCGACGACATCTACCTCGAATACGAGTACTTCGGGCGCAAGGGTCCGTTCGAGCTGTACGGCTACATCGA
CATTCCGAAGATCTTCAACATCGGCAACAGCCACGACAAAGGCGTGTGGGACCATGGCTCGCCGGTGTTCATGGAGCACG
AACCGCGCATCTCCATCGACTACCTCGCCGGGCGCAGCCTGGCCATCGGGCCGTTCAAGGAATGGTACGTGGCGTTCGAC
TGGATCTACGATCACGGCAGCCGCAAAGAGAACCGCGCCAACACGCTGTACAGCGGCTTGGGCACCGACATCGACACCCA
TTCAAGGGTCAATCTGTCGGCCAACCTGTACGGACGCTACCAGTGGGAAAACTACGGGGCCAGCAACGAGTATTCGTGGG
ACGGCTACCGCGCGCAGCTCAAGTACATCGTGCCGATCGACAAATTCAGCAATGGCGCCTCGCTGACCTACATCGGCTTC
ACCAACTTCGATTTCGGCTCGGACCTGCACAAGGACAACCCGGCGCGCACTGCCAATGCCACGGTGGCGACCAACGTCTT
GCTGTACTCGTTCACACACCTGCGTTTCACCCTGGTCGGCCGTTATTTCCACAACGGCGGCAACTGGGAGGACGGCAGCG
AGCTGAACTTCGGCGACGGCAACTTTCGCGCGCGCTCAAACGGCTGGGGTTACTACGCCGGCGTCGGTTATCAATTCTGA

Upstream 100 bases:

>100_bases
CGGCTTGTGCAAACGTTTGCGAGTCGCTGTTGACCGCATTTTCGTTACAAAACCGTACAGGCCCGTGATTCCGGGCCTTG
ATCCGCAAAAAGGACTTTGA

Downstream 100 bases:

>100_bases
ATCAAGGAGCAACCATGAAAGCAATGACGCGTGTATCACTGGCCGCTGCCGCCCTGCTCTCTTCCACCGCATGGGCGGCC
GAGGCACCGATTCAGCCGAA

Product: nucleoside-specific channel-forming protein, Tsx

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MHAFSCHRLRGARTFAVSLLLAGVTGVLSHTALAQPVLPDESAQGEALSPEASPPKKGAYLSDWYNQDLMLIGSKDISFG
PQPADDIYLEYEYFGRKGPFELYGYIDIPKIFNIGNSHDKGVWDHGSPVFMEHEPRISIDYLAGRSLAIGPFKEWYVAFD
WIYDHGSRKENRANTLYSGLGTDIDTHSRVNLSANLYGRYQWENYGASNEYSWDGYRAQLKYIVPIDKFSNGASLTYIGF
TNFDFGSDLHKDNPARTANATVATNVLLYSFTHLRFTLVGRYFHNGGNWEDGSELNFGDGNFRARSNGWGYYAGVGYQF

Sequences:

>Translated_319_residues
MHAFSCHRLRGARTFAVSLLLAGVTGVLSHTALAQPVLPDESAQGEALSPEASPPKKGAYLSDWYNQDLMLIGSKDISFG
PQPADDIYLEYEYFGRKGPFELYGYIDIPKIFNIGNSHDKGVWDHGSPVFMEHEPRISIDYLAGRSLAIGPFKEWYVAFD
WIYDHGSRKENRANTLYSGLGTDIDTHSRVNLSANLYGRYQWENYGASNEYSWDGYRAQLKYIVPIDKFSNGASLTYIGF
TNFDFGSDLHKDNPARTANATVATNVLLYSFTHLRFTLVGRYFHNGGNWEDGSELNFGDGNFRARSNGWGYYAGVGYQF
>Mature_319_residues
MHAFSCHRLRGARTFAVSLLLAGVTGVLSHTALAQPVLPDESAQGEALSPEASPPKKGAYLSDWYNQDLMLIGSKDISFG
PQPADDIYLEYEYFGRKGPFELYGYIDIPKIFNIGNSHDKGVWDHGSPVFMEHEPRISIDYLAGRSLAIGPFKEWYVAFD
WIYDHGSRKENRANTLYSGLGTDIDTHSRVNLSANLYGRYQWENYGASNEYSWDGYRAQLKYIVPIDKFSNGASLTYIGF
TNFDFGSDLHKDNPARTANATVATNVLLYSFTHLRFTLVGRYFHNGGNWEDGSELNFGDGNFRARSNGWGYYAGVGYQF

Specific function: Constitutes the receptor for colicin K and phage T6, and functions as substrate-specific channel for nucleosides and deoxynucleosides [H]

COG id: COG3248

COG function: function code M; Nucleoside-binding outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786612, Length=280, Percent_Identity=51.0714285714286, Blast_Score=282, Evalue=2e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003055
- InterPro:   IPR018013 [H]

Pfam domain/function: PF03502 Channel_Tsx [H]

EC number: NA

Molecular weight: Translated: 35870; Mature: 35870

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAFSCHRLRGARTFAVSLLLAGVTGVLSHTALAQPVLPDESAQGEALSPEASPPKKGAY
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
LSDWYNQDLMLIGSKDISFGPQPADDIYLEYEYFGRKGPFELYGYIDIPKIFNIGNSHDK
HHHHCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEECHHHCCCCCCCCC
GVWDHGSPVFMEHEPRISIDYLAGRSLAIGPFKEWYVAFDWIYDHGSRKENRANTLYSGL
CCCCCCCEEEEECCCCEEEEEECCCEEEECCCHHHEEEEEEEECCCCCCCCHHHHHHHHC
GTDIDTHSRVNLSANLYGRYQWENYGASNEYSWDGYRAQLKYIVPIDKFSNGASLTYIGF
CCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCEEEEEEEEEEECCCCCCCEEEEEEE
TNFDFGSDLHKDNPARTANATVATNVLLYSFTHLRFTLVGRYFHNGGNWEDGSELNFGDG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEHHHCCCCCCCCCCEECCCCC
NFRARSNGWGYYAGVGYQF
CEEECCCCCEEEEECCCCC
>Mature Secondary Structure
MHAFSCHRLRGARTFAVSLLLAGVTGVLSHTALAQPVLPDESAQGEALSPEASPPKKGAY
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
LSDWYNQDLMLIGSKDISFGPQPADDIYLEYEYFGRKGPFELYGYIDIPKIFNIGNSHDK
HHHHCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEECHHHCCCCCCCCC
GVWDHGSPVFMEHEPRISIDYLAGRSLAIGPFKEWYVAFDWIYDHGSRKENRANTLYSGL
CCCCCCCEEEEECCCCEEEEEECCCEEEECCCHHHEEEEEEEECCCCCCCCHHHHHHHHC
GTDIDTHSRVNLSANLYGRYQWENYGASNEYSWDGYRAQLKYIVPIDKFSNGASLTYIGF
CCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCEEEEEEEEEEECCCCCCCEEEEEEE
TNFDFGSDLHKDNPARTANATVATNVLLYSFTHLRFTLVGRYFHNGGNWEDGSELNFGDG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEHHHCCCCCCCCCCEECCCCC
NFRARSNGWGYYAGVGYQF
CEEECCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]