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The map label for this gene is ampC [H]

Identifier: 77459945

GI number: 77459945

Start: 4209023

End: 4210189

Strand: Direct

Name: ampC [H]

Synonym: Pfl01_3723

Alternate gene names: 77459945

Gene position: 4209023-4210189 (Clockwise)

Preceding gene: 77459943

Following gene: 77459947

Centisome position: 65.37

GC content: 59.98

Gene sequence:

>1167_bases
ATGTCTTCGACCAACCTGAGAAAACTCAAGTCCTACAGCGCTTTCGGACTTTTCTTCAGCGCCGCCACCTGTCTGGCAGC
CCCACAAACCGACGATCAGTTACAGGCGCTGGTCAAGGCCACCGTGACCCCGGTCATGCAGCAACAGGACATCGCGGGAC
TGGCCGTAGCCGTGACCGTCAATGGCAAGGCGCATTACTTTAACTACGGTGTCGCCGACAAAAGCACCGGGCAGGCAGTG
AGTGAAAACACCCTGTTCGAAATCGGCTCGGTAAGCAAAACCTTCACCGCGATCCTCGCCGCCTACGCCCAGGCCAGCGG
CAAACTGCAACTCTCCGACAAGGCCAGCCAGCACTGGCCCGAACTGAAAGGCAGCGCCTTCGACCACATCAGCCTGCTGC
AACTGGGCACGTACAGCGCCGGGGGGCTGCCGCTGCAATTCCCGGATGCTGCGGATTCTGCCGACAAGATGCTCGGCTAT
TACCAACAGTGGAAACCGACGTATCCGGCCGGCAGCCATCGCTTGTATTCCAACCCGAGCATCGGCCTGTTCGGCTACCT
GGCCGCAAAAAGCCTCGGTCAGCCGTTCAATCAGGTCATGACCGAAACCCTGCTGCCGAAACTCGGGCTCAAGCACACCT
TCCTGTCGGTGCCCGCGTCTGAACAAAAGCTCTACGCCCAAGGCTATGACAAGAACAACAAACCGATTCGAGTCAGCCCC
GGCGCCCTCGATTCCGAAGCCTACGGCGTGAAAACCAGCGCCGCCGACCTGCTGCAATACGTCCAGGCCAACCTCGACAC
CGCCAAACTCGAAACGCCTCTGCAAAAAGCCATCGCCCTCACCCACACCGGATACTACACCGTCGGCGACATGACCCAGG
GCCTGGGCTGGGAACGCTACGCCTACCCGATCAGCCTCGACCGCCTGCTGGACGGCAACTCGACGCCAATGGCCATGGAG
GCGCACAAGGTCAAATGGCTGAATCCGCCACAGCCTGAACCGGCGAACGTGCTGCTGAACAAGACCGGTTCCACCGGGGG
TTACGGCGCCTACGTCGCATTCGTGCCGTCGAAGAAAGTCGGGATCGTGATTCTGGCGAACCGCAATTATCCGAATGGAG
AGCGGGTGAAGATTGCGCACAGGATTCTGGGGGAATTGACCCGGTAA

Upstream 100 bases:

>100_bases
GGACTGCCTAGATTTGGCGGCGCCGATCAGCAGCCCAATGAAAAAACGCTCGCAGTGTAGCGGGATAACACCATCAACAC
TCATGGAGAGTGGTTCAAAC

Downstream 100 bases:

>100_bases
TCACGCCATAAAAAACGGGCGACCTGAGAAGGTCGCCCGTTTTTCTTTGGGAGGTTGAAAACTACGCCTGTAGCTTCCAA
CCCAGTACATCCATCAGATC

Product: beta-lactamase

Products: NA

Alternate protein names: Cephalosporinase [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSSTNLRKLKSYSAFGLFFSAATCLAAPQTDDQLQALVKATVTPVMQQQDIAGLAVAVTVNGKAHYFNYGVADKSTGQAV
SENTLFEIGSVSKTFTAILAAYAQASGKLQLSDKASQHWPELKGSAFDHISLLQLGTYSAGGLPLQFPDAADSADKMLGY
YQQWKPTYPAGSHRLYSNPSIGLFGYLAAKSLGQPFNQVMTETLLPKLGLKHTFLSVPASEQKLYAQGYDKNNKPIRVSP
GALDSEAYGVKTSAADLLQYVQANLDTAKLETPLQKAIALTHTGYYTVGDMTQGLGWERYAYPISLDRLLDGNSTPMAME
AHKVKWLNPPQPEPANVLLNKTGSTGGYGAYVAFVPSKKVGIVILANRNYPNGERVKIAHRILGELTR

Sequences:

>Translated_388_residues
MSSTNLRKLKSYSAFGLFFSAATCLAAPQTDDQLQALVKATVTPVMQQQDIAGLAVAVTVNGKAHYFNYGVADKSTGQAV
SENTLFEIGSVSKTFTAILAAYAQASGKLQLSDKASQHWPELKGSAFDHISLLQLGTYSAGGLPLQFPDAADSADKMLGY
YQQWKPTYPAGSHRLYSNPSIGLFGYLAAKSLGQPFNQVMTETLLPKLGLKHTFLSVPASEQKLYAQGYDKNNKPIRVSP
GALDSEAYGVKTSAADLLQYVQANLDTAKLETPLQKAIALTHTGYYTVGDMTQGLGWERYAYPISLDRLLDGNSTPMAME
AHKVKWLNPPQPEPANVLLNKTGSTGGYGAYVAFVPSKKVGIVILANRNYPNGERVKIAHRILGELTR
>Mature_387_residues
SSTNLRKLKSYSAFGLFFSAATCLAAPQTDDQLQALVKATVTPVMQQQDIAGLAVAVTVNGKAHYFNYGVADKSTGQAVS
ENTLFEIGSVSKTFTAILAAYAQASGKLQLSDKASQHWPELKGSAFDHISLLQLGTYSAGGLPLQFPDAADSADKMLGYY
QQWKPTYPAGSHRLYSNPSIGLFGYLAAKSLGQPFNQVMTETLLPKLGLKHTFLSVPASEQKLYAQGYDKNNKPIRVSPG
ALDSEAYGVKTSAADLLQYVQANLDTAKLETPLQKAIALTHTGYYTVGDMTQGLGWERYAYPISLDRLLDGNSTPMAMEA
HKVKWLNPPQPEPANVLLNKTGSTGGYGAYVAFVPSKKVGIVILANRNYPNGERVKIAHRILGELTR

Specific function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-C beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=371, Percent_Identity=46.900269541779, Blast_Score=351, Evalue=5e-98,
Organism=Escherichia coli, GI1786574, Length=375, Percent_Identity=21.8666666666667, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001586
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 41922; Mature: 41791

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS00336 BETA_LACTAMASE_C

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTNLRKLKSYSAFGLFFSAATCLAAPQTDDQLQALVKATVTPVMQQQDIAGLAVAVTV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
NGKAHYFNYGVADKSTGQAVSENTLFEIGSVSKTFTAILAAYAQASGKLQLSDKASQHWP
CCCEEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCEEECCCHHHCCC
ELKGSAFDHISLLQLGTYSAGGLPLQFPDAADSADKMLGYYQQWKPTYPAGSHRLYSNPS
CCCCCCCCCEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCC
IGLFGYLAAKSLGQPFNQVMTETLLPKLGLKHTFLSVPASEQKLYAQGYDKNNKPIRVSP
CCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHEECCCCCCCCCEEECC
GALDSEAYGVKTSAADLLQYVQANLDTAKLETPLQKAIALTHTGYYTVGDMTQGLGWERY
CCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCHHHCCCCCEE
AYPISLDRLLDGNSTPMAMEAHKVKWLNPPQPEPANVLLNKTGSTGGYGAYVAFVPSKKV
ECCEEHHHHCCCCCCCEEEECCEEECCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCE
GIVILANRNYPNGERVKIAHRILGELTR
EEEEEECCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSTNLRKLKSYSAFGLFFSAATCLAAPQTDDQLQALVKATVTPVMQQQDIAGLAVAVTV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
NGKAHYFNYGVADKSTGQAVSENTLFEIGSVSKTFTAILAAYAQASGKLQLSDKASQHWP
CCCEEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCEEECCCHHHCCC
ELKGSAFDHISLLQLGTYSAGGLPLQFPDAADSADKMLGYYQQWKPTYPAGSHRLYSNPS
CCCCCCCCCEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCC
IGLFGYLAAKSLGQPFNQVMTETLLPKLGLKHTFLSVPASEQKLYAQGYDKNNKPIRVSP
CCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHEECCCCCCCCCEEECC
GALDSEAYGVKTSAADLLQYVQANLDTAKLETPLQKAIALTHTGYYTVGDMTQGLGWERY
CCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCHHHCCCCCEE
AYPISLDRLLDGNSTPMAMEAHKVKWLNPPQPEPANVLLNKTGSTGGYGAYVAFVPSKKV
ECCEEHHHHCCCCCCCEEEECCEEECCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCE
GIVILANRNYPNGERVKIAHRILGELTR
EEEEEECCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA