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The map label for this gene is sotB [H]

Identifier: 77459914

GI number: 77459914

Start: 4177935

End: 4179227

Strand: Direct

Name: sotB [H]

Synonym: Pfl01_3692

Alternate gene names: 77459914

Gene position: 4177935-4179227 (Clockwise)

Preceding gene: 77459911

Following gene: 77459921

Centisome position: 64.89

GC content: 62.88

Gene sequence:

>1293_bases
ATGTTCGGAACCCTAACCTGTTTTTCCCGAATGTGCAGCGCCCTACCCTATGGCCTTCGTCTCCTTTGGCAAAATGGAAA
TCCGCCCATGAACGATGCGCCACTCACTTCCCCCACGCTCGCTGGCACAGTCGAGCCCGCGGAACGATTACCGCTGGGTG
CATTGCTTGCACTGGCCACCGCCGGGTTCATCACCGTGCTGACCGAGGCAATGCCCGCCGGCCTGCTGCCACAGATGAGC
GCGGGGCTTGATGTCTCTCAAGCCCTGATCGGGCAACTGGTCACGCTGTACGCCATTGGTTCGATGCTGGCGGCGATTCC
GCTCACCATTGCCACACGGGGCTGGCGTCGGCGCCCGCTGTTGCTGGCGGCCATTAGCGGGTTTGCCATCGCCAACAGCA
TCACTGCGTTGTCCGAGCTGTACTGGCTGACCCTGATTGCACGCTTGATCGCAGGCGTGTTCGCGGGGCTGCTCTGGGCT
TTGCTGGCGGGGTACGCGAGCCGGATGGTCACACCTCACTTGCAAGGCAGGGCGATTACGGTGGCCATGCTCGGGGCGCC
GCTTGCGCTGTCGCTGGGCATTCCGGCCGGGACGCTGCTGGGCACGGCAGTCGGCTGGCGCCTGAGCTTCGCGATCATGA
CCGGGCTGACCGTGCTGCTGGTGATCTGGGTGCGTTGGCAAGTACCGGACTTCGCCGGTGAACGCGCCGGAAAGCGCCTG
CCACTGCGTCAGGTGTTTACCTTGCCGGGCGTGCGATCCGTGTTGTTTGTGACTTTGTCCTACGTCGTCGCGCACAACCT
TCTGTACACCTATATCGCGCCATTTCTGGAGCCATCGGGACTTGGCGCAGAAATCGACCGGGTGTTGTTGGTGTTTGGCC
TGGCATCGGTATTGAGCCTGTGGATTGTCGGCAGCCTGATTGATCGCTGGCTGCGTCAATTGGTTCTGGTCAGTGCCGCG
CTGTTCCTGCTGTCGGCGATAGCATTGGGCCTGTGGCGCGAATCGCCGGGTGTGGTCTACACCGCCACCGCCGTCTGGGG
TCTCGCGTTCGGCGCGATGCCCTCACTGTTGCAGACGGCCCTGGCGAAAACCGCCAGGGAGGCTGCCGATACCGCGCAAT
CGATGCTGGTGACCCTGTGGAATGTCGGCATTGCCGGCGGCGGGCTTGCGGGAGGCCTGTTGCTGAACAATCTGGGCGTC
GGGAGTTACCCGTGGCTGGTCGCAGGTCTGTTGCTGCTGACTCTGAATGCGACCGTCAATGCCCGAAGTCATGGCTTCCC
GAACGCGGGATAA

Upstream 100 bases:

>100_bases
GTCTCAGTAAAACTGCGGGTTTCCGCCACCTGCACGAACACCGAAATACTGCCCAGGCTGTCCATTCATCCCTCCCTGAT
TCACGACATTCTTGTCCGAG

Downstream 100 bases:

>100_bases
CGCGCATAAAAAAGCCCCGGATTTTCATCCGGGGCTCGGGTCTTGCAGCTCAGCCAGGCATCAGAAACGCTTGATGTCGG
CTTCGGCTTCCAGCTGCTTG

Product: general substrate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MFGTLTCFSRMCSALPYGLRLLWQNGNPPMNDAPLTSPTLAGTVEPAERLPLGALLALATAGFITVLTEAMPAGLLPQMS
AGLDVSQALIGQLVTLYAIGSMLAAIPLTIATRGWRRRPLLLAAISGFAIANSITALSELYWLTLIARLIAGVFAGLLWA
LLAGYASRMVTPHLQGRAITVAMLGAPLALSLGIPAGTLLGTAVGWRLSFAIMTGLTVLLVIWVRWQVPDFAGERAGKRL
PLRQVFTLPGVRSVLFVTLSYVVAHNLLYTYIAPFLEPSGLGAEIDRVLLVFGLASVLSLWIVGSLIDRWLRQLVLVSAA
LFLLSAIALGLWRESPGVVYTATAVWGLAFGAMPSLLQTALAKTAREAADTAQSMLVTLWNVGIAGGGLAGGLLLNNLGV
GSYPWLVAGLLLLTLNATVNARSHGFPNAG

Sequences:

>Translated_430_residues
MFGTLTCFSRMCSALPYGLRLLWQNGNPPMNDAPLTSPTLAGTVEPAERLPLGALLALATAGFITVLTEAMPAGLLPQMS
AGLDVSQALIGQLVTLYAIGSMLAAIPLTIATRGWRRRPLLLAAISGFAIANSITALSELYWLTLIARLIAGVFAGLLWA
LLAGYASRMVTPHLQGRAITVAMLGAPLALSLGIPAGTLLGTAVGWRLSFAIMTGLTVLLVIWVRWQVPDFAGERAGKRL
PLRQVFTLPGVRSVLFVTLSYVVAHNLLYTYIAPFLEPSGLGAEIDRVLLVFGLASVLSLWIVGSLIDRWLRQLVLVSAA
LFLLSAIALGLWRESPGVVYTATAVWGLAFGAMPSLLQTALAKTAREAADTAQSMLVTLWNVGIAGGGLAGGLLLNNLGV
GSYPWLVAGLLLLTLNATVNARSHGFPNAG
>Mature_430_residues
MFGTLTCFSRMCSALPYGLRLLWQNGNPPMNDAPLTSPTLAGTVEPAERLPLGALLALATAGFITVLTEAMPAGLLPQMS
AGLDVSQALIGQLVTLYAIGSMLAAIPLTIATRGWRRRPLLLAAISGFAIANSITALSELYWLTLIARLIAGVFAGLLWA
LLAGYASRMVTPHLQGRAITVAMLGAPLALSLGIPAGTLLGTAVGWRLSFAIMTGLTVLLVIWVRWQVPDFAGERAGKRL
PLRQVFTLPGVRSVLFVTLSYVVAHNLLYTYIAPFLEPSGLGAEIDRVLLVFGLASVLSLWIVGSLIDRWLRQLVLVSAA
LFLLSAIALGLWRESPGVVYTATAVWGLAFGAMPSLLQTALAKTAREAADTAQSMLVTLWNVGIAGGGLAGGLLLNNLGV
GSYPWLVAGLLLLTLNATVNARSHGFPNAG

Specific function: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites [H]

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family [H]

Homologues:

Organism=Escherichia coli, GI145693198, Length=360, Percent_Identity=27.2222222222222, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787947, Length=329, Percent_Identity=30.3951367781155, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1787808, Length=345, Percent_Identity=28.4057971014493, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786595, Length=356, Percent_Identity=23.0337078651685, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45270; Mature: 45270

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGTLTCFSRMCSALPYGLRLLWQNGNPPMNDAPLTSPTLAGTVEPAERLPLGALLALAT
CCCHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHH
AGFITVLTEAMPAGLLPQMSAGLDVSQALIGQLVTLYAIGSMLAAIPLTIATRGWRRRPL
HHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
LLAAISGFAIANSITALSELYWLTLIARLIAGVFAGLLWALLAGYASRMVTPHLQGRAIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VAMLGAPLALSLGIPAGTLLGTAVGWRLSFAIMTGLTVLLVIWVRWQVPDFAGERAGKRL
EEEECCCHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCC
PLRQVFTLPGVRSVLFVTLSYVVAHNLLYTYIAPFLEPSGLGAEIDRVLLVFGLASVLSL
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
WIVGSLIDRWLRQLVLVSAALFLLSAIALGLWRESPGVVYTATAVWGLAFGAMPSLLQTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHH
LAKTAREAADTAQSMLVTLWNVGIAGGGLAGGLLLNNLGVGSYPWLVAGLLLLTLNATVN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
ARSHGFPNAG
CCCCCCCCCC
>Mature Secondary Structure
MFGTLTCFSRMCSALPYGLRLLWQNGNPPMNDAPLTSPTLAGTVEPAERLPLGALLALAT
CCCHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHH
AGFITVLTEAMPAGLLPQMSAGLDVSQALIGQLVTLYAIGSMLAAIPLTIATRGWRRRPL
HHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
LLAAISGFAIANSITALSELYWLTLIARLIAGVFAGLLWALLAGYASRMVTPHLQGRAIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VAMLGAPLALSLGIPAGTLLGTAVGWRLSFAIMTGLTVLLVIWVRWQVPDFAGERAGKRL
EEEECCCHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCC
PLRQVFTLPGVRSVLFVTLSYVVAHNLLYTYIAPFLEPSGLGAEIDRVLLVFGLASVLSL
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
WIVGSLIDRWLRQLVLVSAALFLLSAIALGLWRESPGVVYTATAVWGLAFGAMPSLLQTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHH
LAKTAREAADTAQSMLVTLWNVGIAGGGLAGGLLLNNLGVGSYPWLVAGLLLLTLNATVN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
ARSHGFPNAG
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]