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The map label for this gene is oprD [H]

Identifier: 77459840

GI number: 77459840

Start: 4089800

End: 4091125

Strand: Direct

Name: oprD [H]

Synonym: Pfl01_3618

Alternate gene names: 77459840

Gene position: 4089800-4091125 (Clockwise)

Preceding gene: 77459839

Following gene: 77459846

Centisome position: 63.52

GC content: 59.5

Gene sequence:

>1326_bases
ATGGTTAACAACACAAAAATGTCGATGGCTGCTCTGGCAGTGGTTGTCGGCGCCGGGCCGTCCACGGTGTTTGCAGAAGA
AAAACCCGAAGGGTTTATCGAAGGCAGCAGCCTGACGGTGCTCAACCGTAACCTCTATTTCAACCGTGACCACCGCAACG
GCCAATCCAGTCCCACGGGCAATGGTTATTCCGAAGCCTGGGCCCACGGCATCATCGGCAAGTTCGAATCCGGTTTCACC
CAGGGCACCGTCGGGGTCGGGGTGGACGCGTTTGCGATGATCGGTCTGAAGCTCGACACCGGTGACGGCCGCAACGGCGG
CCGCAGTTCGTTCGATGTATTGCCGGTCAACAGTGACGGAGAAGCACGGGACGAATACACCAAGGTCGGCGGTGCCGCCA
AAGTGCGGGCCTTCGATACGGTGGTGAAAGTCGGTGATGTGTTCCCGGCCAACCCGGTGGTCGCGGCAGGCGATTCGCGA
TTGCTGCCGGAAAGTTTTCGCGGTGTGACGGCGACCAACACCAGCATCGAAGGTCTGTCGATTCAGGGCGGCCGGTTGCA
TGCGATGAGTCAACCGGTGTCCAGCGACCTGCGCGAGAACTTCGCGACCTTCTATGCCGGCCCGGTCAATTCGCCGTGGA
TCGCTTACGGCGGCGGCGATTACGCGCTGAACAAAAACCTCAGTTTCAGCCTGTATTCCAGTCGCCTGAAAGACGCCTGG
AACCAGTACTACGCCGGCACCGCCTGGACGTATCCGCTGTCGGATGACCTGTCGCTGTTCGGCGGCCTGAACTACTACAA
GGCGATCGACGAAGGCAAACAATTGCTCGGCGAGTTCGACAACAACATCTGGAGCGGCCGCGTCGGCGTGAAACTCGGCG
CCCACTCCGTCGCCATTTCCCACCAGCGCAACAACGGCAACGACGACTTCGATTACCTGCGTCAGTCCGACTCGATCTTC
CTCGACAACTCGATTCAGTACAGCGACTTCAACTCGCCGAAAGAACGTTCGTGGATGGTGCGCTACGACCTCGACATGAC
CACCTATGGCGTGCCGGGCCTGTCGTTCATGAGCCGTTATGCACGCGGCACTGACGCTGACTATTCCAACGCCAACGCCG
TGTACATGCGCCGCGATGCCGAGGGCAATCCGCTGACTGACCAGAAGCGTTGGGAGCGTGATATCGAAGTCAAATACGTG
GTGCAAAGCGGTTCGATGAAGGATCTGTCGCTGCGTCTGCGCCAGGCCACTACCCGCGCCACCGCGTTCGAATCGGATCT
GGATGAAGTGCGGGTGATCGTTGAATACCCGCTGGCGATTCTCTGA

Upstream 100 bases:

>100_bases
CGATGTCACCCGGCGACTCTCCCGGCGGGCCCTTGCCCGTTCGAACAATAAAACCCACGCCGAAGCTCGTTCCCGTTCTG
CCGAACCCAAGGAGTGATTG

Downstream 100 bases:

>100_bases
GTTTCACGAGCAATGCCCATTCACCTTTAGAAGCTCCTTGCTCCTTTGGTAAGAGGTGAATCTTTGGCGTCCTTCGGGGC
GCCTTTTTTATGGATGAAAA

Product: outer membrane porin

Products: NA

Alternate protein names: Imipenem/basic amino acid-specific outer membrane pore; Outer membrane protein D2 [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MVNNTKMSMAALAVVVGAGPSTVFAEEKPEGFIEGSSLTVLNRNLYFNRDHRNGQSSPTGNGYSEAWAHGIIGKFESGFT
QGTVGVGVDAFAMIGLKLDTGDGRNGGRSSFDVLPVNSDGEARDEYTKVGGAAKVRAFDTVVKVGDVFPANPVVAAGDSR
LLPESFRGVTATNTSIEGLSIQGGRLHAMSQPVSSDLRENFATFYAGPVNSPWIAYGGGDYALNKNLSFSLYSSRLKDAW
NQYYAGTAWTYPLSDDLSLFGGLNYYKAIDEGKQLLGEFDNNIWSGRVGVKLGAHSVAISHQRNNGNDDFDYLRQSDSIF
LDNSIQYSDFNSPKERSWMVRYDLDMTTYGVPGLSFMSRYARGTDADYSNANAVYMRRDAEGNPLTDQKRWERDIEVKYV
VQSGSMKDLSLRLRQATTRATAFESDLDEVRVIVEYPLAIL

Sequences:

>Translated_441_residues
MVNNTKMSMAALAVVVGAGPSTVFAEEKPEGFIEGSSLTVLNRNLYFNRDHRNGQSSPTGNGYSEAWAHGIIGKFESGFT
QGTVGVGVDAFAMIGLKLDTGDGRNGGRSSFDVLPVNSDGEARDEYTKVGGAAKVRAFDTVVKVGDVFPANPVVAAGDSR
LLPESFRGVTATNTSIEGLSIQGGRLHAMSQPVSSDLRENFATFYAGPVNSPWIAYGGGDYALNKNLSFSLYSSRLKDAW
NQYYAGTAWTYPLSDDLSLFGGLNYYKAIDEGKQLLGEFDNNIWSGRVGVKLGAHSVAISHQRNNGNDDFDYLRQSDSIF
LDNSIQYSDFNSPKERSWMVRYDLDMTTYGVPGLSFMSRYARGTDADYSNANAVYMRRDAEGNPLTDQKRWERDIEVKYV
VQSGSMKDLSLRLRQATTRATAFESDLDEVRVIVEYPLAIL
>Mature_441_residues
MVNNTKMSMAALAVVVGAGPSTVFAEEKPEGFIEGSSLTVLNRNLYFNRDHRNGQSSPTGNGYSEAWAHGIIGKFESGFT
QGTVGVGVDAFAMIGLKLDTGDGRNGGRSSFDVLPVNSDGEARDEYTKVGGAAKVRAFDTVVKVGDVFPANPVVAAGDSR
LLPESFRGVTATNTSIEGLSIQGGRLHAMSQPVSSDLRENFATFYAGPVNSPWIAYGGGDYALNKNLSFSLYSSRLKDAW
NQYYAGTAWTYPLSDDLSLFGGLNYYKAIDEGKQLLGEFDNNIWSGRVGVKLGAHSVAISHQRNNGNDDFDYLRQSDSIF
LDNSIQYSDFNSPKERSWMVRYDLDMTTYGVPGLSFMSRYARGTDADYSNANAVYMRRDAEGNPLTDQKRWERDIEVKYV
VQSGSMKDLSLRLRQATTRATAFESDLDEVRVIVEYPLAIL

Specific function: Porin with a specificity for basic amino acids. Also possesses serine protease activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oprD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005318 [H]

Pfam domain/function: PF03573 OprD [H]

EC number: NA

Molecular weight: Translated: 48320; Mature: 48320

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNNTKMSMAALAVVVGAGPSTVFAEEKPEGFIEGSSLTVLNRNLYFNRDHRNGQSSPTG
CCCCCHHHHEEEEEEECCCCCCEEECCCCCCEEECCEEEEEECCEEEECCCCCCCCCCCC
NGYSEAWAHGIIGKFESGFTQGTVGVGVDAFAMIGLKLDTGDGRNGGRSSFDVLPVNSDG
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEEECCCC
EARDEYTKVGGAAKVRAFDTVVKVGDVFPANPVVAAGDSRLLPESFRGVTATNTSIEGLS
CCHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHCCEEECCCCCCEEE
IQGGRLHAMSQPVSSDLRENFATFYAGPVNSPWIAYGGGDYALNKNLSFSLYSSRLKDAW
ECCCEEEECCCCHHHHHHHHHHHEEECCCCCCEEEECCCCEEECCCCEEHHHHHHHHHHH
NQYYAGTAWTYPLSDDLSLFGGLNYYKAIDEGKQLLGEFDNNIWSGRVGVKLGAHSVAIS
HHHCCCCEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCEECCEEEEEECCEEEEEE
HQRNNGNDDFDYLRQSDSIFLDNSIQYSDFNSPKERSWMVRYDLDMTTYGVPGLSFMSRY
ECCCCCCCHHHHHHCCCCEEEECCEEECCCCCCCCCCEEEEEECCEEECCCCCHHHHHHH
ARGTDADYSNANAVYMRRDAEGNPLTDQKRWERDIEVKYVVQSGSMKDLSLRLRQATTRA
HCCCCCCCCCCCEEEEEECCCCCCCCCHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHH
TAFESDLDEVRVIVEYPLAIL
HHHHCCHHHHEEHEECCHHCC
>Mature Secondary Structure
MVNNTKMSMAALAVVVGAGPSTVFAEEKPEGFIEGSSLTVLNRNLYFNRDHRNGQSSPTG
CCCCCHHHHEEEEEEECCCCCCEEECCCCCCEEECCEEEEEECCEEEECCCCCCCCCCCC
NGYSEAWAHGIIGKFESGFTQGTVGVGVDAFAMIGLKLDTGDGRNGGRSSFDVLPVNSDG
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEEECCCC
EARDEYTKVGGAAKVRAFDTVVKVGDVFPANPVVAAGDSRLLPESFRGVTATNTSIEGLS
CCHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHCCEEECCCCCCEEE
IQGGRLHAMSQPVSSDLRENFATFYAGPVNSPWIAYGGGDYALNKNLSFSLYSSRLKDAW
ECCCEEEECCCCHHHHHHHHHHHEEECCCCCCEEEECCCCEEECCCCEEHHHHHHHHHHH
NQYYAGTAWTYPLSDDLSLFGGLNYYKAIDEGKQLLGEFDNNIWSGRVGVKLGAHSVAIS
HHHCCCCEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCEECCEEEEEECCEEEEEE
HQRNNGNDDFDYLRQSDSIFLDNSIQYSDFNSPKERSWMVRYDLDMTTYGVPGLSFMSRY
ECCCCCCCHHHHHHCCCCEEEECCEEECCCCCCCCCCEEEEEECCEEECCCCCHHHHHHH
ARGTDADYSNANAVYMRRDAEGNPLTDQKRWERDIEVKYVVQSGSMKDLSLRLRQATTRA
HCCCCCCCCCCCEEEEEECCCCCCCCCHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHH
TAFESDLDEVRVIVEYPLAIL
HHHHCCHHHHEEHEECCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339257; 1427017; 10984043; 8012497; 2118530; 8843159; 9636669 [H]