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The map label for this gene is nuoE [H]

Identifier: 77459828

GI number: 77459828

Start: 4075923

End: 4076420

Strand: Direct

Name: nuoE [H]

Synonym: Pfl01_3606

Alternate gene names: 77459828

Gene position: 4075923-4076420 (Clockwise)

Preceding gene: 77459827

Following gene: 77459829

Centisome position: 63.31

GC content: 62.25

Gene sequence:

>498_bases
ATGAACAGCACGCTTATCCAGACAGACCGTTTCACCTTGAGTGAAACCGAGCGCTCGGCCATCGAGCACGAGCTGCATCA
CTACGAAGACCCGCGCGCGGCGTCGATCGAAGCCTTGAAGATCGTCCAGAAGGAACGCGGCTGGGTGCCGGACGGCGCTC
TGTACGCCATCGGCGAGATCCTCGGCATCCCGGCCAGCGACGTTGAAGGCGTGGCCACGTTCTATAGCCAGATCTTCCGT
CAGCCGGTCGGCCGTCACATCATTCGCGTCTGCGACAGCATGGTCTGCTACATCGGTGGCCACGAGTCGGTGGTCAGCGA
AATCCAGAACAACCTGGGTATCGGCCTGGGTCAGACCACCGCCGACGGTCGCTTCACCCTGCTGCCGGTCTGCTGCCTCG
GCAACTGCGACAAGGCACCGGCGCTGATGATCGATGACGACACCTTTGGCGATGTCCAGCCTGCCGGCGTCGCCAAACTG
CTCGAGGGCTACGTATGA

Upstream 100 bases:

>100_bases
TGCAGCAGATCCCTTCGGTGATCAAAGGCAGCATGGTCGCGGACCTGATTGCGTACCTGGGTAGTATCGACTTCGTTATG
GCCGACGTGGACCGCTAAGC

Downstream 100 bases:

>100_bases
CCCTGACTTCTTTCGGTCCGGCCAACCGCATCCAGCGTTCGGCCGAGACTCACCCGCTGACCTGGCGCCTGCGTGACGAC
GGCGAAGCCGTGTGGCTCGA

Product: NADH dehydrogenase subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MNSTLIQTDRFTLSETERSAIEHELHHYEDPRAASIEALKIVQKERGWVPDGALYAIGEILGIPASDVEGVATFYSQIFR
QPVGRHIIRVCDSMVCYIGGHESVVSEIQNNLGIGLGQTTADGRFTLLPVCCLGNCDKAPALMIDDDTFGDVQPAGVAKL
LEGYV

Sequences:

>Translated_165_residues
MNSTLIQTDRFTLSETERSAIEHELHHYEDPRAASIEALKIVQKERGWVPDGALYAIGEILGIPASDVEGVATFYSQIFR
QPVGRHIIRVCDSMVCYIGGHESVVSEIQNNLGIGLGQTTADGRFTLLPVCCLGNCDKAPALMIDDDTFGDVQPAGVAKL
LEGYV
>Mature_165_residues
MNSTLIQTDRFTLSETERSAIEHELHHYEDPRAASIEALKIVQKERGWVPDGALYAIGEILGIPASDVEGVATFYSQIFR
QPVGRHIIRVCDSMVCYIGGHESVVSEIQNNLGIGLGQTTADGRFTLLPVCCLGNCDKAPALMIDDDTFGDVQPAGVAKL
LEGYV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=154, Percent_Identity=33.7662337662338, Blast_Score=106, Evalue=1e-23,
Organism=Escherichia coli, GI1788621, Length=158, Percent_Identity=68.9873417721519, Blast_Score=242, Evalue=8e-66,
Organism=Caenorhabditis elegans, GI17561328, Length=153, Percent_Identity=37.2549019607843, Blast_Score=116, Evalue=6e-27,
Organism=Drosophila melanogaster, GI18859877, Length=153, Percent_Identity=34.640522875817, Blast_Score=109, Evalue=9e-25,
Organism=Drosophila melanogaster, GI21355353, Length=164, Percent_Identity=29.2682926829268, Blast_Score=90, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 17950; Mature: 17950

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSTLIQTDRFTLSETERSAIEHELHHYEDPRAASIEALKIVQKERGWVPDGALYAIGEI
CCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LGIPASDVEGVATFYSQIFRQPVGRHIIRVCDSMVCYIGGHESVVSEIQNNLGIGLGQTT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCC
ADGRFTLLPVCCLGNCDKAPALMIDDDTFGDVQPAGVAKLLEGYV
CCCCEEEEHEECCCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNSTLIQTDRFTLSETERSAIEHELHHYEDPRAASIEALKIVQKERGWVPDGALYAIGEI
CCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LGIPASDVEGVATFYSQIFRQPVGRHIIRVCDSMVCYIGGHESVVSEIQNNLGIGLGQTT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCC
ADGRFTLLPVCCLGNCDKAPALMIDDDTFGDVQPAGVAKLLEGYV
CCCCEEEEHEECCCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]